Andrea M Haqq

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. ncbi request reprint Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome
    Andrea M Haqq
    Division of Endocrinology, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:174-8. 2003
  2. pmc Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones
    Andrea M Haqq
    Department of Pediatrics, Division of Pediatric Endocrinology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Endocrinol (Oxf) 67:944-51. 2007
  3. ncbi request reprint The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design
    Andrea M Haqq
    Sarah W Stedman Nutrition and Metabolism Center, Duke University, Durham, NC 27705, USA
    Contemp Clin Trials 26:616-25. 2005
  4. ncbi request reprint Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome
    Andrea M Haqq
    Division of Endocrinology, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:3573-6. 2003
  5. ncbi request reprint Effects of growth hormone on pulmonary function, sleep quality, behavior, cognition, growth velocity, body composition, and resting energy expenditure in Prader-Willi syndrome
    Andrea M Haqq
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:2206-12. 2003
  6. pmc Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development
    Andrea M Haqq
    Department of Pediatrics, Division of Pediatric Endocrinology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Endocrinol (Oxf) 69:911-20. 2008
  7. pmc The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain
    Lillian F Lien
    Department of Medicine, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    OMICS 13:21-35. 2009
  8. pmc A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    Christopher B Newgard
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Cell Metab 9:311-26. 2009
  9. pmc The metabolic phenotype of Prader-Willi syndrome (PWS) in childhood: heightened insulin sensitivity relative to body mass index
    Andrea M Haqq
    Division of Pediatric Endocrinology, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Clin Endocrinol Metab 96:E225-32. 2011
  10. pmc Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone
    Krystal A Irizarry
    Division of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC, USA
    Clin Endocrinol (Oxf) 83:797-805. 2015

Research Grants

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Serum ghrelin levels are inversely correlated with body mass index, age, and insulin concentrations in normal children and are markedly increased in Prader-Willi syndrome
    Andrea M Haqq
    Division of Endocrinology, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:174-8. 2003
    ..Elevation of serum ghrelin levels to the degree documented in this study may play a role as an orexigenic factor driving the insatiable appetite and obesity found in PWS...
  2. pmc Altered distribution of adiponectin isoforms in children with Prader-Willi syndrome (PWS): association with insulin sensitivity and circulating satiety peptide hormones
    Andrea M Haqq
    Department of Pediatrics, Division of Pediatric Endocrinology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Endocrinol (Oxf) 67:944-51. 2007
    ..We hypothesized that this increased insulin sensitivity is mediated by increased levels of total and high molecular weight adiponectin and associated with changes in levels of satiety hormones...
  3. ncbi request reprint The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design
    Andrea M Haqq
    Sarah W Stedman Nutrition and Metabolism Center, Duke University, Durham, NC 27705, USA
    Contemp Clin Trials 26:616-25. 2005
    ..Results from this study will expand our knowledge of the biology of obesity and weight regulation and may lead to targeted strategies for its treatment and control...
  4. ncbi request reprint Circulating ghrelin levels are suppressed by meals and octreotide therapy in children with Prader-Willi syndrome
    Andrea M Haqq
    Division of Endocrinology, Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:3573-6. 2003
    ..Further investigation is warranted to determine whether long-term octreotide treatment causes sustained ghrelin suppression, changes eating behavior, and induces weight loss in this population...
  5. ncbi request reprint Effects of growth hormone on pulmonary function, sleep quality, behavior, cognition, growth velocity, body composition, and resting energy expenditure in Prader-Willi syndrome
    Andrea M Haqq
    Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Clin Endocrinol Metab 88:2206-12. 2003
    ..GH intervention improved body composition and REE and may contribute to better sleep quality and pulmonary function. GH administration did not impact fasting ghrelin concentration...
  6. pmc Ghrelin concentrations in Prader-Willi syndrome (PWS) infants and children: changes during development
    Andrea M Haqq
    Department of Pediatrics, Division of Pediatric Endocrinology, Duke University Medical Center, Durham, NC 27710, USA
    Clin Endocrinol (Oxf) 69:911-20. 2008
    ..This progressive weight gain is associated with hyperghrelinaemia and increased insulin sensitivity. The role of ghrelin excess in the pathogenesis of obesity is unclear...
  7. pmc The STEDMAN project: biophysical, biochemical and metabolic effects of a behavioral weight loss intervention during weight loss, maintenance, and regain
    Lillian F Lien
    Department of Medicine, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
    OMICS 13:21-35. 2009
    ..These findings provide evidence for sustained benefits of weight loss in obese humans and insights into mechanisms...
  8. pmc A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
    Christopher B Newgard
    Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27710, USA
    Cell Metab 9:311-26. 2009
    ..Our findings show that in the context of a dietary pattern that includes high fat consumption, BCAA contributes to development of obesity-associated insulin resistance...
  9. pmc The metabolic phenotype of Prader-Willi syndrome (PWS) in childhood: heightened insulin sensitivity relative to body mass index
    Andrea M Haqq
    Division of Pediatric Endocrinology, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    J Clin Endocrinol Metab 96:E225-32. 2011
    ..We hypothesized that metabolic profiles of children with PWS are comparable with those of LC, but different from those of OCs...
  10. pmc Metabolic profiling in Prader-Willi syndrome and nonsyndromic obesity: sex differences and the role of growth hormone
    Krystal A Irizarry
    Division of Pediatric Endocrinology and Diabetes, Duke University Medical Center, Durham, NC, USA
    Clin Endocrinol (Oxf) 83:797-805. 2015
    ..To identify metabolic factors controlling appetite and insulin sensitivity in PWS and assess effects of GH treatment...
  11. doi request reprint Macronutrient Regulation of Ghrelin and Peptide YY in Pediatric Obesity and Prader-Willi Syndrome
    Pinar Gumus Balikcioglu
    Division of Pediatric Endocrinology and Diabetes P G B, M F, Duke University Medical Center, Durham, North Carolina 27710 Advanced Analytics M B, SAS Institute Inc, Cary, North Carolina 27513 Duke Molecular Physiology Institute M J M, M F, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710 Knight Cardiovascular Institute J Q P, Oregon Health and Science University, Portland, Oregon 97239 and Department of Medicine D B and Division of Pediatric Endocrinology and Diabetes A M H, University of Alberta, Edmonton, AB T6G 2R3 Canada
    J Clin Endocrinol Metab 100:3822-31. 2015
    ..The roles of macronutrients and GH in the regulation of food intake in pediatric obesity and Prader-Willi Syndrome (PWS) are poorly understood...
  12. doi request reprint Serum ghrelin concentrations are increased in children with growth hormone insensitivity and decrease during long-term insulinlike growth factor-I treatment
    Aysin Uckun-Kitapci
    Department of Pediatrics, Division of Endocrinology, The University of North Carolina at Chapel Hill, NC, USA
    J Investig Med 56:26-31. 2008
    ....
  13. pmc A case of female epispadias
    Julierut Tantibhedhyangkul
    Division of Reproductive Endocrinology and Fertility, Duke University Medical Center, Durham, North Carolina, USA
    Fertil Steril 90:2017.e1-3. 2008
    ..To present a case of unrecognized female epispadias...
  14. pmc Effects of higher dietary protein intake on energy balance and metabolic control in children with long-chain 3-hydroxy acyl-CoA dehydrogenase (LCHAD) or trifunctional protein (TFP) deficiency
    Melanie B Gillingham
    The Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA
    Mol Genet Metab 90:64-9. 2007
    ..Long-term studies are needed to determine whether higher protein diets will reduce the risk of overweight and obesity in children with LCHAD or TFP deficiency...
  15. doi request reprint Do surrogate markers for adiposity relate to cytokines in adolescents?
    Daniela A Rubin
    Department of Kinesiology, California State University Fullerton, Fullerton, CA 92834 3599, USA
    J Investig Med 56:786-92. 2008
    ..To determine the associations between field-collected surrogates of adiposity and concentrations of resistin, tumor necrosis factor alpha (TNF-alpha), interleukin-6 (IL-6), and adiponectin in youth...
  16. pmc The association between insulin resistance and cytokines in adolescents: the role of weight status and exercise
    Daniela A Rubin
    Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Metabolism 57:683-90. 2008
    ..Increased adiposity, resulting in reduced adiponectin and increased resistin and TNF-alpha, may link these cytokines with IR in adolescents...
  17. ncbi request reprint Poverty, obesity, and malnutrition: an international perspective recognizing the paradox
    Sherry A Tanumihardjo
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Am Diet Assoc 107:1966-72. 2007
    ..Informing current practitioners, educators, and policymakers and passing this information on to future generations of nutrition students is of paramount importance...

Research Grants1

  1. Developmental, nutritional and hormonal reg. of Ghrelin
    Andrea Haqq; Fiscal Year: 2008
    ..Our studies should provide novel insights into the role of ghrelin and other hormones and adipocytokines in the regulation of body weight in both children with Prader-willi syndrome and normal children. ..