Megan E B Clowse
Affiliation: Duke University Medical Center
- Racial and Ethnic Disparities in the Pregnancies of Women With Systemic Lupus ErythematosusMegan E B Clowse
Duke University, Durham, North Carolina
Arthritis Care Res (Hoboken) 68:1567-72. 2016....
- Pregnancy Outcomes in Subjects Exposed to Certolizumab PegolMegan E B Clowse
From Duke University Medical Center, Durham Union Chimique Belge UCB Pharma, Raleigh, North Carolina Atlanta Gastroenterology Associates, Atlanta, Georgia Baylor Research Institute and Baylor University Medical Center, Dallas, Texas University of California San Francisco UCSF Center for Colitis and Crohn s Disease, San Francisco, California, USA Department of Rheumatology, Immunology and Allergology, Inselspital, University of Bern, Bern, Switzerland UCB Pharma, Brussels, Belgium M E Clowse, MD, Duke University Medical Center D C Wolf, MD, Atlanta Gastroenterology Associates F Förger, MD, Department of Rheumatology and Immunology and Allergology, Inselspital, University of Bern J J Cush, MD, Baylor Research Institute and Baylor University Medical Center A Golembesky, PhD, UCB Pharma L Shaughnessy, PhD, UCB Pharma D De Cuyper, MD, UCB Pharma U Mahadevan, MD, UCSF Center for Colitis and Crohn s Disease
J Rheumatol 42:2270-8. 2015..To provide information on pregnancy outcomes in women receiving certolizumab pegol (CZP)...
- The use of anti-TNFα medications for rheumatologic disease in pregnancyMegan Eb Clowse
Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
Int J Womens Health 2:199-209. 2010..Prior to using these medications during pregnancy, the risks and benefits of these drugs, other treatment options, and the ongoing inflammatory condition all must be carefully weighed by both doctor and patient...
- Predictors of preterm birth in patients with mild systemic lupus erythematosusMegan E B Clowse
Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Ann Rheum Dis 72:1536-9. 2013..Biomarkers that would identify at-risk pregnancies could allow interventions to prevent preterm birth...
- Pregnancy outcomes among patients with vasculitisMegan E B Clowse
Duke University Medical Center, Durham, NC 27710, USA
Arthritis Care Res (Hoboken) 65:1370-4. 2013..Pregnancy outcomes of patients with vasculitis are unknown, but are of great concern to patients and physicians. Through an online survey, this study assessed pregnancy outcomes among patients with vasculitis...
- A national study of the complications of lupus in pregnancyMegan E B Clowse
Department of Medicine, Division of Rheumatology and Immunology, Duke University School of Medicine, Durham, NC 27710, USA
Am J Obstet Gynecol 199:127.e1-6. 2008..This study was undertaken to determine the risk of rare complications during pregnancy for women with systemic lupus erythematosus...
- Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's)Megan E B Clowse
Duke University Medical Center, Durham, North Carolina, USA
Arthritis Care Res (Hoboken) 63:1777-81. 2011..In this study, we assessed the rate of diminished ovarian reserve in women with GPA who received CYC versus methotrexate (MTX)...
- The clinical utility of measuring complement and anti-dsDNA antibodies during pregnancy in patients with systemic lupus erythematosusMegan E B Clowse
Division of Rheumatology, Duke University Medical Center, Durham, North Carolina, USA
J Rheumatol 38:1012-6. 2011..The importance of low complement and anti-dsDNA during pregnancy in patients with systemic lupus erythematosus (SLE) is poorly defined. We investigated the effect of these laboratory tests and clinical SLE activity on pregnancy outcomes...
- Hydroxychloroquine in lupus pregnancyMegan E B Clowse
Duke University Medical Center, Durham, North Carolina 27710, USA
Arthritis Rheum 54:3640-7. 2006..The purpose of this study was to examine lupus activity and pregnancy outcomes in women with SLE treated or not treated with HCQ during pregnancy...
- Lupus activity in pregnancyMegan E B Clowse
Division of Rheumatology and Immunology, Duke University Medical Center, Box 3535 Trent Drive, Durham, NC 27710, USA
Rheum Dis Clin North Am 33:237-52, v. 2007..Fortunately, the majority of pregnancies in women with SLE are successful. However, the interaction between pregnancy and SLE activity can lead to complications for both mother and baby...
- Managing contraception and pregnancy in the rheumatologic diseasesMegan E B Clowse
Department of Rheumatology and Immunology Duke University Health System, Durham, UK
Best Pract Res Clin Rheumatol 24:373-85. 2010..The expected post-partum arthritis flare may be avoided by restarting medications soon after delivery. Judicious use of medication and close observation may be the keys to successful pregnancy in women with rheumatologic disease...
- Ovarian preservation by GnRH agonists during chemotherapy: a meta-analysisMegan E B Clowse
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
J Womens Health (Larchmt) 18:311-9. 2009..We performed a systematic review of studies examining whether a GnRHa administered during chemotherapy is protective of ovarian function and fertility...
- Early risk factors for pregnancy loss in lupusMegan E B Clowse
Department of Medicine, Division of Rheumatology, Duke University Medical Center, Durham, NC 27110, USA
Obstet Gynecol 107:293-9. 2006..To identify early risk factors for pregnancy loss in lupus pregnancies...
- Depressive symptoms and associated factors in systemic lupus erythematosusDavid E Karol
Duke University Medical Center, Durham, NC
Psychosomatics 54:443-50. 2013..Depressive symptoms affect anywhere from 11% to 71% of patients with systemic lupus erythematosus (SLE), which may be related to SLE disease activity, other clinical variables, or sociodemographic factors...
- Maternal autoantibody levels in congenital heart block and potential prophylaxis with antiinflammatory agentsRobert D Tunks
Division of Pediatric Cardiology, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA
Am J Obstet Gynecol 208:64.e1-7. 2013..The importance of maternal autoantibody levels in congenital heart block and elucidation of maternal factors that may reduce disease burden require further clarification...
- Effects of infertility, pregnancy loss, and patient concerns on family size of women with rheumatoid arthritis and systemic lupus erythematosusMegan E B Clowse
Duke University Medical Center, Durham, North Carolina, USA
Arthritis Care Res (Hoboken) 64:668-74. 2012..We sought to determine the roles of infertility, pregnancy loss, and personal choice on family size in women with these diseases...
- The management of rheumatic diseases in pregnancyK Mitchell
Division of Rheumatology and Immunology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA
Scand J Rheumatol 39:99-108. 2010..Therefore, continued immunosuppression with the least risky medications will allow for the most optimal pregnancy outcomes...
- Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results from the Phase 3, Randomized, Double-blind, Placebo-controlled Trials, EMBODY™ 1 and EMBODY™ 2Megan E B Clowse
Duke University Medical Center, Durham, USA
Arthritis Rheumatol . 2016..5-39.8%). No new safety signals were identified. Conclusions Treatment with epratuzumab+ST did not result in improvements in response rates over placebo+ST. This article is protected by copyright. All rights reserved...
- Late ovarian hyperstimulation syndrome after controlled ovarian stimulation in a woman with systemic lupus erythematosus and lupus nephritisJohn R Crochet
Division of Reproductive Endocrinology and Fertility, Department of Obstetrics and Gynecology, Duke University Hospital, Durham, North Carolina, USA
Fertil Steril 95:1786.e13-6. 2011..To report a case of late ovarian hyperstimulation syndrome (OHSS) in a woman with lupus nephritis undergoing controlled ovarian stimulation and in vitro fertilization (IVF) with subsequent transfer into a gestational surrogate...
- Digital necrosis related to carboplatin and gemcitabine therapy in systemic sclerosisMegan E B Clowse
Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
J Rheumatol 30:1341-3. 2003..This case illustrates the risk of severe digital ischemia and digital loss in patients with scleroderma during chemotherapy with carboplatin and gemcitabine...
- The impact of increased lupus activity on obstetric outcomesMegan E B Clowse
Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Arthritis Rheum 52:514-21. 2005..Systemic lupus erythematosus is associated with multiple adverse pregnancy outcomes. We examined the impact of disease activity on spontaneous abortions, perinatal mortality, preterm delivery, and birth weight...