James Z Appel

Summary

Affiliation: Duke University Medical Center
Country: USA

Publications

  1. pmc Characterization of the innate immune response to chronic aspiration in a novel rodent model
    James Z Appel
    Transplant Immunobiology Laboratory, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Respir Res 8:87. 2007
  2. ncbi Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1049-57. 2006
  3. ncbi Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation
    Matthew G Hartwig
    Department of Surgery, Duke University, Durham, NC, USA
    J Thorac Cardiovasc Surg 131:209-17. 2006
  4. ncbi Antireflux surgery in the setting of lung transplantation: strategies for treating gastroesophageal reflux disease in a high-risk population
    Matthew G Hartwig
    Division of Thoracic Surgery, Duke University Medical Center, Department of Surgery, Box 3864, Durham, NC 27710, USA
    Thorac Surg Clin 15:417-27. 2005
  5. doi Rabbit anti-thymocyte globulin induction therapy does not prolong survival after lung transplantation
    Matthew G Hartwig
    Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Heart Lung Transplant 27:547-53. 2008
  6. ncbi Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation
    Matthew G Hartwig
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transplantation 80:320-5. 2005
  7. ncbi Improved results treating lung allograft failure with venovenous extracorporeal membrane oxygenation
    Matthew G Hartwig
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 80:1872-9; discussion 1879-80. 2005
  8. ncbi Utility of peritransplant and rescue intravenous immunoglobulin and extracorporeal immunoadsorption in lung transplant recipients sensitized to HLA antigens
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Hum Immunol 66:378-86. 2005
  9. ncbi J. Maxwell Chamberlain Memorial Paper. Early fundoplication prevents chronic allograft dysfunction in patients with gastroesophageal reflux disease
    Edward Cantu
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Thorac Surg 78:1142-51; discussion 1142-51. 2004
  10. ncbi Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1686-94. 2006

Collaborators

Detail Information

Publications12

  1. pmc Characterization of the innate immune response to chronic aspiration in a novel rodent model
    James Z Appel
    Transplant Immunobiology Laboratory, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Respir Res 8:87. 2007
    ..A novel rodent model of chronic aspiration was therefore developed in order to investigate the resulting innate immune response in the lung...
  2. ncbi Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1049-57. 2006
    ..A virtual crossmatch strategy using flow cytometry, which enables precise determination of HLA-specific antibody specificity, was compared to prospective crossmatching in sensitized lung transplant candidates...
  3. ncbi Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation
    Matthew G Hartwig
    Department of Surgery, Duke University, Durham, NC, USA
    J Thorac Cardiovasc Surg 131:209-17. 2006
    ..In this study, we used a model of rat lung transplantation to test the hypothesis that chronic aspiration of gastric contents accelerates pulmonary allograft dysfunction...
  4. ncbi Antireflux surgery in the setting of lung transplantation: strategies for treating gastroesophageal reflux disease in a high-risk population
    Matthew G Hartwig
    Division of Thoracic Surgery, Duke University Medical Center, Department of Surgery, Box 3864, Durham, NC 27710, USA
    Thorac Surg Clin 15:417-27. 2005
    ..Perioperative care should involve a multidisciplinary approach, including physicians and other health care providers familiar with the complexities of lung transplant recipients...
  5. doi Rabbit anti-thymocyte globulin induction therapy does not prolong survival after lung transplantation
    Matthew G Hartwig
    Division of Thoracic Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Heart Lung Transplant 27:547-53. 2008
    ..Thus, we hypothesized that RATG induction would translate to reduced BOS and improved long-term graft survival...
  6. ncbi Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation
    Matthew G Hartwig
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Transplantation 80:320-5. 2005
    ..We hypothesized that isolated HBcAb+ donors represent minimal risk of viral transmission in vaccinated lung transplant (LTx) recipients...
  7. ncbi Improved results treating lung allograft failure with venovenous extracorporeal membrane oxygenation
    Matthew G Hartwig
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 80:1872-9; discussion 1879-80. 2005
    ..We hypothesized that venovenous membrane oxygenation provides a safer alternative than venoarterial support for lung recipients suffering from primary graft failure...
  8. ncbi Utility of peritransplant and rescue intravenous immunoglobulin and extracorporeal immunoadsorption in lung transplant recipients sensitized to HLA antigens
    James Z Appel
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Hum Immunol 66:378-86. 2005
    ..We discuss the appropriateness and clinical impact of IVIG and ECI in sensitized lung transplant recipients as well as cellular mechanisms that may contribute...
  9. ncbi J. Maxwell Chamberlain Memorial Paper. Early fundoplication prevents chronic allograft dysfunction in patients with gastroesophageal reflux disease
    Edward Cantu
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Ann Thorac Surg 78:1142-51; discussion 1142-51. 2004
    ..We hypothesized that treatment of reflux with early fundoplication would prevent bronchiolitis obliterans syndrome and improve survival...
  10. ncbi Effect of an anti-C5a monoclonal antibody indicates a prominent role for anaphylatoxin in pulmonary xenograft dysfunction
    Jeffrey G Gaca
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Transplantation 81:1686-94. 2006
    ..The current study investigates the role of C5a in pulmonary xenograft failure in baboons...
  11. doi Aprotinin's effect on blood product transfusion in off-pump bilateral lung transplantation
    Keki R Balsara
    Department of Surgery, Box 3443, Duke University Medical Center, Durham, NC 27710, USA
    Interact Cardiovasc Thorac Surg 8:45-8. 2009
    ..These findings suggest that aprotinin administration should be considered for all patients undergoing OP-BOLT to reduce exposure to blood products and potential immune sensitization and infectious complications...
  12. ncbi Cryopreservation and mycophenolate therapy are detrimental to hematopoietic progenitor cells
    Leo Buhler
    Transplantation Biology Research Center, Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
    Transplantation 74:1159-66. 2002
    ..The aim of the present study was to determine whether certain components of nonmyeloablative regimens for hematopoietic cell transplantation might compromise the growth of hematopoietic progenitors...