Genomes and Genes
Mark S Lechner
Affiliation: Drexel University
- Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegationKasirajan Ayyanathan
The Wistar Institute, Philadelphia, Pennsylvania 19104 4268, USA
Genes Dev 17:1855-69. 2003..Thus, like variegation in Drosophila, recruitment of mammalian HP1 to a euchromatic promoter can establish a silenced state that is epigenetically heritable...
- The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domainMark S Lechner
The Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104, USA
Biochem Biophys Res Commun 331:929-37. 2005..Thus, this spectrum of direct binding partners suggests an expanded role for HP1 as factor participating in promoter-enhancer communication, chromatin remodeling/assembly, and sub-nuclear compartmentalization...