TIMOTHY CUNNINGHAM

Summary

Affiliation: Drexel University College of Medicine
Country: USA

Publications

  1. pmc Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9
    Timothy J Cunningham
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA
    J Neuroinflammation 3:25. 2006
  2. pmc Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis
    Timothy J Cunningham
    Department of Neurobiology, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA
    J Neuroinflammation 3:26. 2006
  3. pmc Secreted phospholipase A2 involvement in neurodegeneration: differential testing of prosurvival and anti-inflammatory effects of enzyme inhibition
    Shuyan Chen
    Department of Anatomy and Neurobiology, College of Medicine, Drexel University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e39257. 2012
  4. pmc Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties
    Timothy J Cunningham
    Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
    J Inflamm (Lond) 5:17. 2008

Research Grants

  1. SURVIVAL AND DEATH OF NEURONS
    TIMOTHY CUNNINGHAM; Fiscal Year: 2003

Collaborators

  • Shuyan Chen
  • Lihua Yao

Detail Information

Publications4

  1. pmc Inhibition of secreted phospholipase A2 by neuron survival and anti-inflammatory peptide CHEC-9
    Timothy J Cunningham
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA
    J Neuroinflammation 3:25. 2006
    ..The results highlight the advantages of inhibitors with uncompetitive properties for inflammatory disorders including those resulting in degeneration of neurons...
  2. pmc Secreted phospholipase A2 activity in experimental autoimmune encephalomyelitis and multiple sclerosis
    Timothy J Cunningham
    Department of Neurobiology, Drexel University College of Medicine, 2900 Queen Lane, Philadelphia, PA 19129, USA
    J Neuroinflammation 3:26. 2006
    ..The purpose of this study was to test the involvement of systemic secreted phospholipase A2 (sPLA2) enzymes in experimental autoimmune encephalomyelitis (EAE), an MS model, and to determine if enzyme activity is elevated in MS patients...
  3. pmc Secreted phospholipase A2 involvement in neurodegeneration: differential testing of prosurvival and anti-inflammatory effects of enzyme inhibition
    Shuyan Chen
    Department of Anatomy and Neurobiology, College of Medicine, Drexel University, Philadelphia, Pennsylvania, United States of America
    PLoS ONE 7:e39257. 2012
    ..Testing potential anti-inflammatory/neuroprotective compounds with these human cell lines and their conditioned media may provide a useful screening tool prior to in vivo therapeutic applications...
  4. pmc Product inhibition of secreted phospholipase A2 may explain lysophosphatidylcholines' unexpected therapeutic properties
    Timothy J Cunningham
    Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA
    J Inflamm (Lond) 5:17. 2008
    ....

Research Grants1

  1. SURVIVAL AND DEATH OF NEURONS
    TIMOTHY CUNNINGHAM; Fiscal Year: 2003
    ..It is expected that these experiments will provide further insights into mechanisms and potential therapies for neuron degeneration after CNS injury and in nervous system diseases. ..