Dean E Wilcox

Summary

Affiliation: Dartmouth Medical School
Country: USA

Publications

  1. doi request reprint Arsenic. Can this toxic metalloid sustain life?
    Dean E Wilcox
    Department of Chemistry, Dartmouth College, Hanover, NH, 03755, USA
    Met Ions Life Sci 13:475-98. 2013
  2. pmc Dosimetry based on EPR spectral analysis of fingernail clippings
    Dean E Wilcox
    Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
    Health Phys 98:309-17. 2010
  3. pmc Electron paramagnetic resonance dosimetry for a large-scale radiation incident
    Harold M Swartz
    Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 103:255-67. 2012
  4. pmc Development and validation of an ex vivo electron paramagnetic resonance fingernail biodosimetric method
    Xiaoming He
    Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
    Radiat Prot Dosimetry 159:172-81. 2014
  5. doi request reprint Thermodynamic contributions to the stability of the insulin hexamer
    George P Lisi
    Department of Chemistry, Dartmouth College, 6128 Burke Laboratory, Hanover, New Hampshire 03755, United States
    Biochemistry 53:3576-84. 2014
  6. doi request reprint Thermodynamics of Zn2+ binding to Cys2His2 and Cys2HisCys zinc fingers and a Cys4 transcription factor site
    Anne M Rich
    Department of Chemistry, Dartmouth College Hanover, New Hampshire 03755, USA
    J Am Chem Soc 134:10405-18. 2012
  7. ncbi request reprint Oxygen effects on the EPR signals from wood charcoals: experimental results and the development of a model
    Oleg Y Grinberg
    EPR Center for the Study of Viable Systems, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Phys Chem B 111:13316-24. 2007
  8. doi request reprint Thermodynamics of formation of the insulin hexamer: metal-stabilized proton-coupled assembly of quaternary structure
    Margaret C Carpenter
    Department of Chemistry, Dartmouth College, 6128 Burke Laboratory, Hanover, New Hampshire 03755, United States
    Biochemistry 53:1296-301. 2014
  9. doi request reprint Application of isothermal titration calorimetry in bioinorganic chemistry
    Nicholas E Grossoehme
    Department of Chemistry, 6128 Burke Laboratory, Dartmouth College, Hanover, NH 03755, USA
    J Biol Inorg Chem 15:1183-91. 2010
  10. pmc Stabilization of Cu(I) for binding and calorimetric measurements in aqueous solution
    Destinee K Johnson
    Department of Chemistry, Physics and Geology, Winthrop University, Rock Hill, SC 27933, USA
    Dalton Trans 44:16494-505. 2015

Collaborators

Detail Information

Publications13

  1. doi request reprint Arsenic. Can this toxic metalloid sustain life?
    Dean E Wilcox
    Department of Chemistry, Dartmouth College, Hanover, NH, 03755, USA
    Met Ions Life Sci 13:475-98. 2013
    ..Both of these topics are considered in the context of the toxicity of this element and its ability to cause cancer and other diseases, yet its Janus-faced ability to effectively treat APL. ..
  2. pmc Dosimetry based on EPR spectral analysis of fingernail clippings
    Dean E Wilcox
    Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
    Health Phys 98:309-17. 2010
    ..Second, decomposition of the EPR spectra from irradiated fingernails into MIS and RIS components can be used to isolate and thus quantify the RIS for determining individual exposure dose...
  3. pmc Electron paramagnetic resonance dosimetry for a large-scale radiation incident
    Harold M Swartz
    Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 103:255-67. 2012
    ..The authors conclude that electron paramagnetic resonance dosimetry is likely to be a useful part of triage for a large-scale radiation incident...
  4. pmc Development and validation of an ex vivo electron paramagnetic resonance fingernail biodosimetric method
    Xiaoming He
    Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA Department of Chemistry, Dartmouth College, Hanover, NH 03755, USA
    Radiat Prot Dosimetry 159:172-81. 2014
    ....
  5. doi request reprint Thermodynamic contributions to the stability of the insulin hexamer
    George P Lisi
    Department of Chemistry, Dartmouth College, 6128 Burke Laboratory, Hanover, New Hampshire 03755, United States
    Biochemistry 53:3576-84. 2014
    ..Finally, Zn(2+) in excess of the two that are required to form the hexamer further stabilizes the protein by additional enthalpic contributions. ..
  6. doi request reprint Thermodynamics of Zn2+ binding to Cys2His2 and Cys2HisCys zinc fingers and a Cys4 transcription factor site
    Anne M Rich
    Department of Chemistry, Dartmouth College Hanover, New Hampshire 03755, USA
    J Am Chem Soc 134:10405-18. 2012
    ..While dominated by Zn(2+) coordination to the cysteines and histidines, other residues in the sequence affect the protein contributions that modulate the stability of these motifs...
  7. ncbi request reprint Oxygen effects on the EPR signals from wood charcoals: experimental results and the development of a model
    Oleg Y Grinberg
    EPR Center for the Study of Viable Systems, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
    J Phys Chem B 111:13316-24. 2007
    ..An attenuated, but similar, EPR response to oxygen by chars when they are immersed in aqueous solution is attributed to water competition with oxygen for adsorption on the char surface...
  8. doi request reprint Thermodynamics of formation of the insulin hexamer: metal-stabilized proton-coupled assembly of quaternary structure
    Margaret C Carpenter
    Department of Chemistry, Dartmouth College, 6128 Burke Laboratory, Hanover, New Hampshire 03755, United States
    Biochemistry 53:1296-301. 2014
    ..The former is due to Zn(2+) coordination to His residues from three subunits, and the latter is associated with desolvation that accompanies the protonation and the packing of the subunits in the hexamer. ..
  9. doi request reprint Application of isothermal titration calorimetry in bioinorganic chemistry
    Nicholas E Grossoehme
    Department of Chemistry, 6128 Burke Laboratory, Dartmouth College, Hanover, NH 03755, USA
    J Biol Inorg Chem 15:1183-91. 2010
    ....
  10. pmc Stabilization of Cu(I) for binding and calorimetric measurements in aqueous solution
    Destinee K Johnson
    Department of Chemistry, Physics and Geology, Winthrop University, Rock Hill, SC 27933, USA
    Dalton Trans 44:16494-505. 2015
    ....
  11. doi request reprint Isothermal Titration Calorimetry Measurements of Metal Ions Binding to Proteins
    Colette F Quinn
    Department of Chemistry, Dartmouth College, Hanover, New Hampshire, USA
    Methods Enzymol 567:3-21. 2016
    ..This analysis also quantifies the number of protons that are displaced when the metal ion binds to the protein. ..
  12. pmc A metal switch for controlling the activity of molecular motor proteins
    Jared C Cochran
    Dartmouth College, Department of Chemistry, Hanover, New Hampshire, USA
    Nat Struct Mol Biol 19:122-7. 2012
    ..In human kinesin-1 and kinesin-5 as well as Drosophila melanogaster kinesin-10 and kinesin-14, this defect is rescued by Mn(2+), providing a way to control both the enzymatic activity and force-generating ability of these nanomachines...
  13. doi request reprint Monomethylarsenite competes with Zn2+ for binding sites in the glucocorticoid receptor
    Anne M Spuches
    Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA
    J Am Chem Soc 130:8148-9. 2008
    ....