Genomes and Genes
Dartmouth Medical School
Organization: Dartmouth Medical School
- How does neuroscience affect our conception of volition?Adina L Roskies
Department of Philosophy, Dartmouth College, Hanover, New Hampshire 03755, USA
Annu Rev Neurosci 33:109-30. 2010..Still, the picture emerging from neuroscience does raise new questions, and ultimately may put pressure on some intuitive notions about what is necessary for free will...
- beta-Glucocerebrosidase activity in the stratum corneum of house sparrows following acclimation to high and low humidityRobert M Cox
Department of Evolution, Ecology, and Organismal Biology, Ohio State University, Columbus, Ohio 43210, USA
Physiol Biochem Zool 81:97-105. 2008..Our results demonstrate physiological plasticity in CWL and provide tentative support for a role of beta -GlcCer'ase in mediating this response...
- Extending the P4P agenda, part 2: how Medicare can reduce waste and improve the care of the chronically illJohn E Wennberg
Dartmouth Institute for Health Policy and Clinical Practice, USA
Health Aff (Millwood) 26:1575-85. 2007..This paper recommends a strategy for achieving this goal...
- Sample size and optimal design for logistic regression with binary interactionEugene Demidenko
Dartmouth Medical School, Hanover, NH 03755, U S A
Stat Med 27:36-46. 2008..Our sample size and power calculations with interaction can be carried out online at www.dartmouth.edu/ approximately eugened...
- Automatic activation of categorical and abstract analogical relations in analogical reasoningAdam E Green
Department of Psychological and Brain Sciences, Dartmouth College, 6207 Moore Hall, Hanover, NH 03755, USA
Mem Cognit 34:1414-21. 2006..This finding lends empirical support to the hypothesis that, when people comprehend the analogy between two items, they activate an abstract analogical relation that is distinct from the specific content items that compose the analogy...
- For richer or poorer? Evaluating the President's Council on BioethicsRonald M Green
Ethics Institute, 6031 Parker House, Dartmouth College, Hanover, NH 03755 3500, USA
HEC Forum 18:108-24. 2006
- Human prostacyclin receptor structure and function from naturally-occurring and synthetic mutationsJeremiah Stitham
Department of Pharmacology and Toxicology, Dartmouth Medical School, 7650 Remsen, Hanover, NH 03755, USA
Prostaglandins Other Lipid Mediat 82:95-108. 2007..The aim of this review is to summarize the most recent findings regarding hIP receptor structure-function that have developed through the study of both synthetic and naturally-occurring mutations...
- Contour discontinuities subserve two types of form analysis that underlie motion processingPeter Ulric Tse
H B 6207, Moore Hall, Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755, USA
Prog Brain Res 154:271-92. 2006..In both cases the analysis of form must proceed in parallel with the analysis of motion, in order to constrain the ongoing analysis of motion...
- Children with a TV in their bedroom at higher risk for being overweightA M Adachi-Mejia
Community Health Research Program, Hood Center for Children and Families, Dartmouth Medical School, Lebanon, NH 03756 0001, USA
Int J Obes (Lond) 31:644-51. 2007..We examined having a TV in the bedroom as a risk factor for child overweight...
- Rural-urban disparities in health-related quality of life within disease categories of VeteransWilliam B Weeks
VA Outcomes Group Research Enhancement Award Program, White River Junction, VT, USA
J Rural Health 22:204-11. 2006..Compared to their urban counterparts, rural veterans have been found to have lower health-related quality of life...
- Resource planning for patient-centered, collaborative careJohn H Wasson
Dartmouth Medical School, Hanover, NH 03755, USA
J Ambul Care Manage 29:207-14. 2006..We conclude that modern technologies and related approaches make resource planning for patient-centered, collaborative care feasible and desirable...
- Medication nonadherence in older people with serious mental illness: prevalence and correlatesSarah I Pratt
Dartmouth Medical School NH, Dartmouth Psychiatric Research Center, NH 03301, USA
Psychiatr Rehabil J 29:299-310. 2006....
- Normalizing motor-related brain activity: subthalamic nucleus stimulation in Parkinson diseaseS T Grafton
Center for Cognitive Neuroscience, Dartmouth College, Hanover, NH 03755, USA
Neurology 66:1192-9. 2006....
- Transcriptional activation by the Myc oncoproteinM D Cole
Department of Pharmacology, Dartmouth Medical School, Lebanon, NH 03756, USA
Curr Top Microbiol Immunol 302:33-50. 2006..Understanding the molecular basis of Myc function has been a central issue in the fields of cancer biology and signal transduction for 20 years...
- Electromyography of intrinsic laryngeal muscles by Fritz BuchthalWalter M St-John
Department of Physiology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
Exp Physiol 93:210-2. 2008
- T-SPOT.TB Test(R) results in adults with Mycobacterium avium complex pulmonary diseaseLisa V Adams
Section of Infectious Disease and International Health, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
Scand J Infect Dis 40:196-203. 2008..Reactions to the T-SPOT.TB Test may persist months to years after treatment of tuberculosis...
- Charting a path for innovative toilet technology using multicriteria decision analysisMark E Borsuk
Eawag, Swiss Federal Institute of Aquatic Science and Technology, 8600 Dubendorf, Switzerland
Environ Sci Technol 42:1855-62. 2008....
- Taking the MINI to Mustang, Nepal: methodological and epistemological translations of an illness narrative interview toolSienna R Craig
Department of Anthropology, Dartmouth College, Hanover, NH 03755, USA
Anthropol Med 17:1-26. 2010..Concluding recommendations are made regarding the adaptation of this tool to other settings...
- Remission of paroxysmal atrial fibrillation with iron reduction in haemophilia AL R Zacharski
Section of Hematology Oncology, Department of Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
Haemophilia 16:726-30. 2010....
- Word and pseudoword superiority effects reflected in the ERP waveformDonna Coch
Dartmouth College, Department of Education, Reading Brains Lab, USA
Brain Res 1329:159-74. 2010..Results suggest that orthographic fluency is reflected in both lower-level, sublexical, perceptual processing and higher-level, lexical processing in fluently reading adults...
- Shared decision making in mental health: prospects for personalized medicineRobert E Drake
Dartmouth Psychiatric Research Center, Lebanon, New Hampshire 03766, USA
Dialogues Clin Neurosci 11:455-63. 2009..The future of personalized medicine is clearly linked with our ability to create the infrastructure and cultural receptivity to these changes...
- Racial, socioeconomic, and rural-urban disparities in obesity-related bariatric surgeryAmy E Wallace
Veterans Rural Health Resource Center Eastern Region, VAMC 11Q, WRJ, VT 05009, USA
Obes Surg 20:1354-60. 2010..We examined the likelihood of bariatric surgery among morbidly obese patients across rural/urban locales, racial/ethnic groups, insurance categories, socioeconomic, and comorbidity levels...
- A case series investigating acceptance and commitment therapy as a treatment for previously treated, unremitted patients with anorexia nervosaM I Berman
Dartmouth Medical School, Lebanon, NH 03756 0001, USA
Eur Eat Disord Rev 17:426-34. 2009..These data, although preliminary, suggest that ACT could be a promising treatment for subthreshold or clinical cases of AN, even with chronic participants or those with medical complications...
- Atlasin GTPases shape up ER networksCharles Barlowe
Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
Dev Cell 17:157-8. 2009..Recent studies reveal that the integral membrane atlastin GTPases, which are linked to neurodegenerative diseases, catalyze membrane fusion and are required for the formation of branched membrane networks characteristic of the ER...
- What rate of utilization is appropriate in musculoskeletal care?Jon D Lurie
Dartmouth Medical School and The Dartmouth Institute for Health Policy and Clinical Practice TDI, DHMC One Medical Center Drive, Lebanon, NH 03756, USA
Clin Orthop Relat Res 467:2506-11. 2009..The recommended approach in this setting is the use of decision aids and other approaches to informed choice. Level of Evidence: Level V, expert opinion. See Guidelines for Authors for a complete description of levels of evidence...
- Optimizing multi-center perfusion dataDonald S Likosky
The Dartmouth Institute for Health Policy and Clinical Practice, Hanover, New Hampshire, USA
J Extra Corpor Technol 41:P7-10. 2009..This manuscript addresses the following principles: the quality of the datasets, the use of the data to inform practice, and developing and maintaining social capital...
- An adaptable-multilayer fractional fourier transform approach for image registrationWei Pan
Computer Science Department, Dartmouth College, Hanover, NH 03755, USA
IEEE Trans Pattern Anal Mach Intell 31:400-14. 2009....
- Do medullary serotonin neurones modulate the ventilatory response to hypoxia?Eugene Nattie
Department of Physiology, Dartmouth Medical School, Lebanon, NH, USA
Acta Physiol (Oxf) 193:309. 2008
- B cell survival: an unexpected mechanism of lymphocyte vitalityMicah J Benson
Department of Microbiology and Immunology, Dartmouth Medical School and the Norris Cotton Cancer Center, Lebanon, NH 03756, USA
Immunol Cell Biol 86:485-6. 2008
- Endoscopy in Barrett's oesophagus: adherence to standards and neoplasia detection in the community practice versus hospital settingH Pohl
Department of Gastroenterology, Charite University Hospitals, Berlin, Germany
J Intern Med 264:370-8. 2008..We aimed at comparing adherence to guidelines and neoplasia detection rates in medical centres (MC) and community practices (CP)...
- Prevalence of clinically important histology in small adenomasLynn F Butterly
Dartmouth Hitchcock Medical Center, Gastroenterology, Lebanon, New Hampshire 03756, USA
Clin Gastroenterol Hepatol 4:343-8. 2006..We evaluated the prevalence of advanced histology in small and diminutive adenomas to clarify their clinical importance in terms of malignant potential...
- Statistical comparison of color cancer cell imagesEugene Demidenko
Dartmouth Medical School, Lebanon, NH 03756, USA
Oncol Rep 15:1077-9. 2006..We applied a well-established multivariate analysis of variances (MANOVA) on the logit scale so that image comparison was reduced to the classic chi-square test...
- Effects of hypoxia on the complexity of respiratory patterns during maturationMetin Akay
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755, USA
Early Hum Dev 70:55-71. 2002..001). These findings suggest that during hypoxic gasping, regardless of degree of development, the output of the central pattern generator becomes less complex probably because hypoxia reduces the neural activity...
- COPII-dependent transport from the endoplasmic reticulumCharles Barlowe
Department of Biochemistry, Dartmouth Medical School, Hanover, NH 03755, USA
Curr Opin Cell Biol 14:417-22. 2002..Other advances have shown that integral membrane accessory proteins act with the COPII coat to collect specific cargo molecules into ER-derived transport vesicles...
- Gender and fitness to stand trial. A 5-year review of remands in QuébecAnne G Crocker
New Hampshire Dartmouth Psychiatric Research Center and Department of Psychiatry, Dartmouth Medical School, Main Building, 105 Pleasant Street, Concord, NH 03301, USA
Int J Law Psychiatry 25:67-84. 2002
- News media coverage of screening mammography for women in their 40s and tamoxifen for primary prevention of breast cancerLisa M Schwartz
VA Outcomes Group, Department of Veterans Affairs Medical Center, White River Junction, VT 05009, USA
JAMA 287:3136-42. 2002....
- A healthy understanding of intraflagellar transportRoger D Sloboda
Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
Cell Motil Cytoskeleton 52:1-8. 2002....
- Clinal variation at microsatellite loci reveals historical secondary intergradation between glacial races of Coregonus artedi (Teleostei: Coregoninae)J Turgeon
Departement de Biologie, Universite Laval, Ste Foy, Quebec, Canada
Evolution 55:2274-86. 2001..This historical signal of equilibrium contrasted with the current migration-drift disequilibrium within major extant watersheds and was apparently maintained by high effective population sizes and low migration regimes...
- Actin nucleation: nucleation-promoting factors are not all equalH N Higgs
Department of Biochemistry, 413 Vail Building, HB 7200, Dartmouth Medical School, Hanover, New Hampshire 03755 3844, USA
Curr Biol 11:R1009-12. 2001..A recent study has revealed marked differences in the ability of two nucleation-promoting factors - N-WASP and Scar/WAVE1 - to activate the Arp2/3 complex. Further insights have come from determination of the Arp2/3 crystal structure...
- Managing comorbid schizophrenia and substance abuseR E Drake
New Hampshire Dartmouth Psychiatric Research Center, 2 Whipple Place, Lebanon, NH, 03766, USA
Curr Psychiatry Rep 3:418-22. 2001..Further research is needed to refine specific interventions and to improve knowledge regarding implementing integrated treatment settings in routine mental health programs...
- Social patterns of substance use among people with dual diagnosesH Alverson
Department of Anthropology, Dartmouth College, Hanover, New Hampshire 03755 3570, USA
Ment Health Serv Res 3:3-14. 2001..Many social functions provided by these social patterns must be continued by other means if clients, once persuaded to attempt abstinence, are to be effectively supported in their sobriety...
- Ocular pursuit of predicted motion trajectoriesK Kveraga
Department of Psychological and Brain Sciences, Dartmouth College, Hanover, NH 03755 6207, USA
Exp Brain Res 138:393-7. 2001....
- Family treatment and medication dosage reduction in schizophrenia: effects on patient social functioning, family attitudes, and burdenK T Mueser
New Hampshire Dartmouth Psychiatric Research Center and Department of Psychiatry, Dartmouth Medical School, USA
J Consult Clin Psychol 69:3-12. 2001..The addition of time-limited behavioral family therapy to monthly support groups improved family atmosphere, but did not influence patient social functioning or family burden...
- Is unplanned return to the operating room a useful quality indicator in general surgery?J D Birkmeyer
VA Outcomes Group 111B, Department of Veterans Affairs Medical Center, White River Junction, VT 05009, USA
Arch Surg 136:405-11. 2001..To test our hypothesis that unplanned return to the operating room (OR) is a useful quality indicator, we examined how often and for what reasons patients go back to the OR in a broad-based general surgery practice...
- Potential benefits of regionalizing major surgery in Medicare patientsJ D Birkmeyer
Department of Veterans Affairs Medical Center, White River Junction, VT, USA
Eff Clin Pract 2:277-83. 1999..We explored the potential benefits of regionalizing 10 high-risk procedures for the 38 million Americans enrolled in Medicare...
- Maternal employment and overweight childrenPatricia M Anderson
Department of Economics, Dartmouth College, Hanover, NH 03755 3514, USA
J Health Econ 22:477-504. 2003..Analyses by subgroups show that it is higher socioeconomic status mothers whose work intensity is particularly deleterious for their children's overweight status...
- Displacement estimation with co-registered ultrasound for image guided neurosurgery: a quantitative in vivo porcine studyKaren E Lunn
Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA
IEEE Trans Med Imaging 22:1358-68. 2003....
- Collaborating to integrate curriculum in primary care medical education: successes and challenges from three US medical schoolsCatherine F Pipas
Department of Community and Family Medicine, Dartmouth Medical School, USA
Fam Med 36:S126-32. 2004..This paper describes the approaches, successes, and challenges three institutions experienced when implementing an interdepartmental collaboration to create an integrated primary care clerkship experience...
- Analysis of sampling volume and tissue heterogeneity on the in vivo detection of fluorescenceBrian W Pogue
Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, USA
J Biomed Opt 10:41206. 2005..In summary, sampling fiber size affects the fluorescence intensities detected and use of multiple region microscopic sampling could provide better information about the distribution of values that occur...
- Survival following total hip replacementJane Barrett
Department of Medicine, Section of Biostatistics and Epidemiology, Dartmouth Medical School, Evergreen Building, Suite 300, 46 Centerra Parkway, Lebanon, NH 03766, USA
J Bone Joint Surg Am 87:1965-71. 2005..The purpose of our investigation was to assess whether the association had the characteristics of a causal relationship or whether it might appear to be due to comorbidity or other factors...
- Impact and temporal trends of percutaneous coronary intervention in the drug-eluting stent versus bare metal stent erasCraig A Thompson
Cardiology Section, Dartmouth Hitchcock Medical Center, Dartmouth Medical School, Lebanon, New Hampshire, USA
Am J Cardiol 96:668-72. 2005....
- Paired helical filaments (PHFs) are a family of single filament structures with a common helical turn period: negatively stained PHF imaged by TEM and measured before and after sonication, deglycosylation, and dephosphorylationGeorge C Ruben
Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
Microsc Res Tech 67:175-95. 2005..5-0.6 nm and 0.7-1.0 nm, respectively, and the right-hand helicity of the PHF was lost after deglycosylation. Dephosphorylation with PP-2A reduced the PHF wide regions by 6.0 nm and the thin regions by 2.6 nm...
- Quality of life of long-term survivors of breast cancer and lymphoma treated with standard-dose chemotherapy or local therapyTim A Ahles
Department of Psychiatry and Center for Psycho Oncology Research, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
J Clin Oncol 23:4399-405. 2005..This study compared the quality of life (QOL) of long-term survivors of breast cancer and lymphoma who had been treated with standard-dose systemic chemotherapy or local therapy only...
- Epithelial cells in the female reproductive tract: a central role as sentinels of immune protectionCharles R Wira
Department of Physiology, Dartmouth Medical School, Lebanon, NH, USA
Am J Reprod Immunol 53:65-76. 2005..In this article, we will outline how polarized epithelial cells function as the first line of defense against potential pathogens in the female reproductive tract...
- Neurologic injury associated with CABG surgery: outcomes, mechanisms, and opportunities for improvementDonald S Likosky
Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Heart Surg Forum 7:E650-62. 2004..We conclude this article by providing insight regarding areas requiring further investigation in order to reduce sustainably the risk of these iatrogenic events among patient undergoing CABG surgery...
- Role of a cytotoxic-T-lymphocyte epitope-defined, alternative gag open reading frame in the pathogenesis of a murine retrovirus-induced immunodeficiency syndromeArti Gaur
Department of Microbiology and Immunology, Norris Cancer Center, Dartmouth Medical School, Lebanon, NH 03756, USA
J Virol 79:4308-15. 2005..Our data strongly suggest the existence of a novel ORF2 product(s) that is required for LP-BM5-induced pathogenesis and have potentially broad implications for other retroviral diseases...
- Advances in the production of human therapeutic proteins in yeasts and filamentous fungiTillman U Gerngross
Thayer School of Engineering, The Department of Biological Sciences, Dartmouth College, Hanover, New Hampshire 03755, USA
Nat Biotechnol 22:1409-14. 2004....
- Statistical estimation of resistance/conductance by electrical impedance tomography measurementsEugene Demidenko
Department of Mathematics, Dartmouth College, 7927 Rubin, DHMC, Lebanon, NH 03756, USA
IEEE Trans Med Imaging 23:829-38. 2004..Our theory may be applied to various tests including EIT hardware calibration and whether the medium is homogeneous. These tests are illustrated on phantom agar data...
- Persistent diarrhea, arthritis, and other complications of enteric infections: a pilot survey based on California FoodNet surveillance, 1998-1999Judy R Rees
California Emerging Infections Program, Oakland, CA, USA
Clin Infect Dis 38:S311-7. 2004..Three respondents reported hair loss. The frequency, nature, and etiology of these complications merit further investigation...
- Prion protein conversion in vitroSurachai Supattapone
Departments of Biochemistry and Medicine, Dartmouth Medical School, Hanover, NH 03755, USA
J Mol Med (Berl) 82:348-56. 2004..Future studies using in vitro PrPres conversion and amplification assays promise to provide new mechanistic insights about the PrP conversion process, and to generate clinically useful tools...
- Multi-frequency electrical impedance tomography of the breast: new clinical resultsNirmal K Soni
Thayer School of Engineering, Dartmouth College, 8000 Cummings Hall, Hanover, NH 03755 8000, USA
Physiol Meas 25:301-14. 2004..Tissues with high radiodensity also had increased conductivity and permittivity...
- Common threads in eukaryotic circadian systemsJ C Dunlap
Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA
Curr Opin Genet Dev 8:400-6. 1998..Post-transcriptional control governs the amount and type of FRQ and makes the clock responsive to temperature...
- TEN YEAR FOLLOW-UP OF DUAL DIAGNOSIS TREATMENTRobert Drake; Fiscal Year: 2002..g., gastritis). The results will be of interest to policy makers in many states that are replicating the model of integrated dual-diagnosis services that has been used in New Hampshire since 1988. ..
- ASSERTIVE COMMUNITY TREATMENT FOR THE DUALLY DIAGNOSEDRobert Drake; Fiscal Year: 2004..Finally, we will take maximal advantage of conducting the rural and urban studies in conjunction with one another. ..
- LUNG FUNCTION IN PROLONGED HEART FAILURERobert Drake; Fiscal Year: 2001..After 7 days, the lungs will be analyzed to determine if connective tissue content and lung fluid have increased. These studies will test a previously unknown mechanism for the pulmonary edema associated with heart failure. ..
- Cognitive-Behavioral Treatment of PTSD in SMI ClientsKim Mueser; Fiscal Year: 2004....
- Cognitive Behavioral Treatment of PTSD in SMI ClientsKim Mueser; Fiscal Year: 2007..The results of this research will bring the field one step closer to having an evidence-based practice for trauma and PTSD in clients with SMI. ..
- Cognitive Behavioral Treatment of PTSD in SMI ClientsKim T Mueser; Fiscal Year: 2010..The results of this research will bring the field one step closer to having an evidence-based practice for trauma and PTSD in clients with SMI. ..
- FAMILY INTERVENTION FOR SMI AND SUBSTANCE USE DISORDERSKim Mueser; Fiscal Year: 2005..Improvements in these areas may the have long-term benefit of maintaining family involvement with dually diagnosed clients, thereby reducing housing instability and homelessness. ..
- MECHANISMS AND SITES OF VENTILATORY NEUROGENESISWALTER ST JOHN; Fiscal Year: 2003..Such information might provide insights into dysfunctions of the control of ventilation in humans, such as in "sleep apneas" or the "sudden infant death syndrome." ..
- MECHANISMS AND SITES OF VENTILATORY NEUROGENESISWALTER ST JOHN; Fiscal Year: 2007..Such information might provide insights into dysfunctions of the control of ventilation in humans, such as in "sleep apnea" or the "sudden infant death syndrome." ..
- CSF AND THE CENTRAL CHEMICAL CONTROL OF BREATHINGEugene Nattie; Fiscal Year: 2007....
- CSF and the central chemical control of breathing.Eugene Edward Nattie; Fiscal Year: 2010..Abnormal central chemoreception is a key defect in the congenital central hypoventilation syndrome and is hypothesized to play a role in the Sudden Infant Death Syndrome. ..
- MECHANISMS AND SITES OF VENTILATORY NEUROGENESISWALTER ST JOHN; Fiscal Year: 1993....
- MECHANISMS AND SITES OF VENTILATORY NEUROGENESISWALTER ST JOHN; Fiscal Year: 1990..We believe that results of studies proposed herein will provide significant insights into the mechanisms responsible for the neurogenesis of automatic ventilatory activity...
- MECHANISMS AND SITES OF VENTILATORY NEUROGENESISWALTER ST JOHN; Fiscal Year: 1999..Results will provide a basis for understanding the failure of mechanisms for ventilatory neurogenesis, in apneas of neonates and adults. ..
- Effect of Biomechanical Force Exposure on Cognition and Brain Activation in TBIThomas McAllister; Fiscal Year: 2007....
- DOPAMINERGIC MODULATION WORKING MEMORY TBI--FMRI STUDYThomas McAllister; Fiscal Year: 2003..Performance and fMRI visualized activation of WM circuitry will be characterized at baseline (on placebo) and following administration of a dopamine agonist. ..