Richard J Powell

Summary

Affiliation: Dartmouth-Hitchcock Medical Center
Country: USA

Publications

  1. ncbi request reprint Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial
    Richard J Powell
    Division of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Vasc Med 9:193-8. 2004
  2. ncbi request reprint Early results of carotid stent placement for treatment of extracranial carotid bifurcation occlusive disease
    Richard J Powell
    Division of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 39:1193-9. 2004
  3. ncbi request reprint Pro: Carotid angioplasty and stenting will be the first-line interventional therapy for stroke prevention in patients with extracranial carotid occlusive disease
    Richard J Powell
    Department of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Cardiothorac Vasc Anesth 19:539-41. 2005
  4. ncbi request reprint Comparison of embolization protection device-specific technical difficulties during carotid artery stenting
    Richard J Powell
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 44:56-61. 2006
  5. ncbi request reprint Stent-graft treatment of a large internal carotid artery vein graft aneurysm
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    J Vasc Surg 37:1310-3. 2003
  6. doi request reprint Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia
    Richard J Powell
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    Circulation 118:58-65. 2008
  7. pmc The impact of adjunctive iliac stenting on femoral-femoral bypass in contemporary practice
    Chetan P Huded
    Dartmouth Medical School, Hanover, NH 03756, USA
    J Vasc Surg 55:739-45; discussion 744-5. 2012
  8. pmc The financial implications of endovascular aneurysm repair in the cost containment era
    David H Stone
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 59:283-290, 290.e1. 2014
  9. doi request reprint Long-term results of combined common femoral endarterectomy and iliac stenting/stent grafting for occlusive disease
    Robert W Chang
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 48:362-7. 2008
  10. ncbi request reprint Mesenteric stenting for chronic mesenteric ischemia
    David J Brown
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 42:268-74. 2005

Detail Information

Publications72

  1. ncbi request reprint Therapeutic angiogenesis for critical limb ischemia: design of the hepatocyte growth factor therapeutic angiogenesis clinical trial
    Richard J Powell
    Division of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Vasc Med 9:193-8. 2004
    ..In conclusion, this study will help to determine whether therapeutic angiogenesis with HGF is a viable option in the treatment of patients with CLI...
  2. ncbi request reprint Early results of carotid stent placement for treatment of extracranial carotid bifurcation occlusive disease
    Richard J Powell
    Division of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 39:1193-9. 2004
    ..Most patients were selected for CAS if they had indications for endarterectomy (CEA) but were considered at high risk for surgery...
  3. ncbi request reprint Pro: Carotid angioplasty and stenting will be the first-line interventional therapy for stroke prevention in patients with extracranial carotid occlusive disease
    Richard J Powell
    Department of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Cardiothorac Vasc Anesth 19:539-41. 2005
  4. ncbi request reprint Comparison of embolization protection device-specific technical difficulties during carotid artery stenting
    Richard J Powell
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 44:56-61. 2006
    ..This study compares the technical difficulties encountered using these two types of EPD...
  5. ncbi request reprint Stent-graft treatment of a large internal carotid artery vein graft aneurysm
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    J Vasc Surg 37:1310-3. 2003
    ..The stent graft was then placed with embolization protection. The repair was performed without complication, and the aneurysm remained successfully excluded at 6-month follow-up...
  6. doi request reprint Results of a double-blind, placebo-controlled study to assess the safety of intramuscular injection of hepatocyte growth factor plasmid to improve limb perfusion in patients with critical limb ischemia
    Richard J Powell
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    Circulation 118:58-65. 2008
    ....
  7. pmc The impact of adjunctive iliac stenting on femoral-femoral bypass in contemporary practice
    Chetan P Huded
    Dartmouth Medical School, Hanover, NH 03756, USA
    J Vasc Surg 55:739-45; discussion 744-5. 2012
    ..Most reports of femoral-femoral bypass (FFB) were published before the era of endovascular intervention. This study examines the utilization and impact of adjunctive endovascular intervention on FFB in contemporary practice...
  8. pmc The financial implications of endovascular aneurysm repair in the cost containment era
    David H Stone
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 59:283-290, 290.e1. 2014
    ..Such costs place EVAR at odds with efforts to constrain healthcare expenditures. This study examines the procedure-associated costs and operating margins associated with EVAR at a tertiary care academic medical center...
  9. doi request reprint Long-term results of combined common femoral endarterectomy and iliac stenting/stent grafting for occlusive disease
    Robert W Chang
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 48:362-7. 2008
    ..Common femoral artery (CFA) endarterectomy with iliac stenting or stent grafting can be an alternative to traditional open surgery in patients with aortoiliac occlusive disease. We report the long-term outcomes of this approach...
  10. ncbi request reprint Mesenteric stenting for chronic mesenteric ischemia
    David J Brown
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 42:268-74. 2005
    ..We review our initial experience to examine short-term outcomes...
  11. pmc Clinical effectiveness of secondary interventions for restenosis after renal artery stenting
    Thomas A Simone
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA
    J Vasc Surg 58:687-94. 2013
    ..Secondary interventions for renal artery restenosis (RAS) after renal artery stenting are common, despite limited data about their effectiveness. This study was designed to evaluate the outcomes of endovascular treatment of recurrent RAS...
  12. doi request reprint Factors associated with amputation or graft occlusion one year after lower extremity bypass in northern New England
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    Ann Vasc Surg 24:57-68. 2010
    ..Therefore, we examined risk factors that predict amputation or graft occlusion within the first year following lower extremity bypass...
  13. ncbi request reprint Restenosis in gold-coated renal artery stents
    Brian W Nolan
    Division of Vascular Surgery, Dartmouth Hitchcock Medical Center, NH 03756, USA
    J Vasc Surg 42:40-6. 2005
    ..There is conflicting evidence regarding restenosis with gold-coated stents. To evaluate the effect of gold coating on restenosis after renal stenting, we reviewed the results of all patients undergoing RAS in our practice...
  14. doi request reprint The value of 3D-CT angiographic assessment prior to carotid stenting
    Mark C Wyers
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA
    J Vasc Surg 49:614-22. 2009
    ..We evaluated the use of multidetector CT angiography with three-dimensional reconstruction (3D-CTA) as a noninvasive screening tool for prospective CAS patients...
  15. ncbi request reprint Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling
    Kathleen A Martin
    Division of Vascular Surgery, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    J Biol Chem 282:36112-20. 2007
    ....
  16. ncbi request reprint Early results of stent-grafting to treat diffuse aortoiliac occlusive disease
    Eva M Rzucidlo
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    J Vasc Surg 37:1175-80. 2003
    ..We evaluated the results of stent-graft placement as an option for treatment of these diseases...
  17. pmc Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target of rapamycin complex 1 and FoxO4
    Min Ding
    Section of Vascular Surgery, Department of Surgery, Dartmouth Medical School, Lebanon, NH, USA
    Arterioscler Thromb Vasc Biol 31:1403-10. 2011
    ..The adipocyte-secreted hormone adiponectin exerts important cardioprotective and antidiabetic effects. Little is known about its effect on vascular smooth muscle cells (VSMC), key cells in restenosis, hypertension, and atherosclerosis...
  18. ncbi request reprint Internal iliac occlusion without coil embolization during endovascular abdominal aortic aneurysm repair
    Mark C Wyers
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 36:1138-45. 2002
    ..In this study, we evaluated the outcomes of this approach...
  19. pmc Validation of the Society for Vascular Surgery's objective performance goals for critical limb ischemia in everyday vascular surgery practice
    Philip P Goodney
    Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 54:100-108.e4. 2011
    ..It remains unknown, however, if these targets can be achieved in everyday vascular surgery practice...
  20. ncbi request reprint Outcomes of renal artery angioplasty and stenting using low-profile systems
    Brian W Nolan
    Division of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 41:46-52. 2005
    ..We evaluated the outcomes and complications of RAS performed by vascular surgeons at our institution with modern low-profile systems...
  21. pmc Clopidogrel is not associated with major bleeding complications during peripheral arterial surgery
    David H Stone
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 54:779-84. 2011
    ..The purpose of this study was to determine whether preoperative clopidogrel use was associated with significant bleeding complications during peripheral arterial surgery...
  22. pmc Cilostazol is associated with improved outcomes after peripheral endovascular interventions
    Courtney J Warner
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 59:1607-14. 2014
    ..We assessed the effect of cilostazol on outcomes after peripheral vascular interventions using meta-analytic techniques...
  23. ncbi request reprint Prediction of early graft failure with intraoperative completion duplex ultrasound scan
    Eva M Rzucidlo
    Dartmouth Hitchcock Medical Center, Lebannon, New Hampshire 03756, USA
    J Vasc Surg 36:975-81. 2002
    ..The purpose of this study was to determine intraoperative hemodynamic parameters that predict early failure of infragenicular vein grafts with intraoperative completion duplex ultrasound scan...
  24. doi request reprint Endovascular treatment in the superficial femoral artery: which devices, where?
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Semin Vasc Surg 21:180-5. 2008
    ..In the current report, the available comparative data, single-arm trials, and registry data are reviewed and device recommendations are proposed based on TASC II classification, lesion morphology, and indication...
  25. ncbi request reprint Blinded comparison of preoperative duplex ultrasound scanning and contrast arteriography for planning revascularization at the level of the tibia
    Jason A Grassbaugh
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Dr, Lebanon, NH 03756, USA
    J Vasc Surg 37:1186-90. 2003
    ..We examined whether preoperative duplex ultrasound scanning (DU) could replace contrast material-enhanced arteriography (CA) in selecting the recipient artery of tibial or peroneal artery bypass grafts...
  26. pmc Lovastatin induces VSMC differentiation through inhibition of Rheb and mTOR
    Robert J Wagner
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Am J Physiol Cell Physiol 299:C119-27. 2010
    ..In conclusion, these findings illustrate a mechanism for the cardioprotective effects of lovastatin through inhibition of Rheb and mTORC1 and promotion of a differentiated VSMC phenotype...
  27. ncbi request reprint Endovascular repair of abdominal aortic aneurysm without preoperative arteriography
    Mark C Wyers
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 38:730-8. 2003
    ....
  28. pmc Cellular therapy with Ixmyelocel-T to treat critical limb ischemia: the randomized, double-blind, placebo-controlled RESTORE-CLI trial
    Richard J Powell
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Mol Ther 20:1280-6. 2012
    ..Treatment effect in post hoc analyses of patients with baseline wounds was more pronounced (TTF: P < 0.0001, AFS: P = 0.0802, logrank test). Ixmyelocel-T treatment was well tolerated and may offer a potential new treatment option...
  29. doi request reprint Prevalence and clinical significance of stent fracture and deformation following carotid artery stenting
    Catherine K Chang
    Department of Surgery, Division of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 54:685-90. 2011
    ..Carotid artery stenting (CAS) is a developing intervention for carotid artery stenosis, and long-term outcomes remain unclear. We examined the prevalence and clinical significance of carotid stent fractures or deformations following CAS...
  30. ncbi request reprint Endothelial cell activation of the smooth muscle cell phosphoinositide 3-kinase/Akt pathway promotes differentiation
    David J Brown
    Department of Surgery, Section of Vascular Surgery, Hitchcock Medical Center, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 41:509-16. 2005
    ..We aimed to determine the intracellular signaling mechanisms by which ECs promote a differentiated SMC phenotype...
  31. doi request reprint Neuroprotection during carotid artery stenting using the GORE flow reversal system: 30-day outcomes in the EMPiRE Clinical Study
    Daniel G Clair
    Department of Vascular Surgery, Heart and Vascular Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio 44195, USA
    Catheter Cardiovasc Interv 77:420-9. 2011
    ....
  32. ncbi request reprint Retrograde mesenteric stenting during laparotomy for acute occlusive mesenteric ischemia
    Mark C Wyers
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03766, USA
    J Vasc Surg 45:269-75. 2007
    ....
  33. doi request reprint Stent graft repair of iatrogenic femoral arteriovenous fistula: a useful therapeutic approach in a hostile groin
    Randall R De Martino
    Section of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Vasc Endovascular Surg 44:40-3. 2010
    ..She remains asymptomatic at 15 months with ongoing resolution of the AVF. This report highlights the utility of stent-graft repair of an IFAVF in high surgical risk patients or in those with ''hostile'' anatomy...
  34. ncbi request reprint Shifting Wallgraft position: case reports and review of the forces affecting Wallgraft positioning
    David R Whittaker
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 43:383-7. 2006
    ..During subsequent treatment, the stent-grafts were noted to be in different positions from where they were initially deployed. A discussion of the possible explanations for the shifting positions follows...
  35. doi request reprint Interim analysis results from the RESTORE-CLI, a randomized, double-blind multicenter phase II trial comparing expanded autologous bone marrow-derived tissue repair cells and placebo in patients with critical limb ischemia
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 54:1032-41. 2011
    ..This study was conducted to assess the safety and clinical efficacy of intramuscular injection of autologous tissue repair cells (TRCs)...
  36. pmc Early discharge does not increase readmission or mortality after high-risk vascular surgery
    Benjamin S Brooke
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    J Vasc Surg 57:734-40. 2013
    ..To address this question, we examined the relationship between early discharge and 30-day outcomes among patients undergoing a high-risk vascular surgery procedure, thoracic aortic aneurysm (TAA) repair...
  37. ncbi request reprint "Medical high risk" designation is not associated with survival after carotid artery stenting
    Theodore H Yuo
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 47:356-62. 2008
    ..While medical high risk (MHR) has been proposed as an indication for carotid artery stenting (CAS), the impact of MHR on long-term survival and stroke after CAS has not been described...
  38. ncbi request reprint Anatomic characteristics of ruptured abdominal aortic aneurysm on conventional CT scans: Implications for rupture risk
    Mark F Fillinger
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03750, USA
    J Vasc Surg 39:1243-52. 2004
    ....
  39. ncbi request reprint Current status of carotid artery stenting
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03765, USA
    J Vasc Surg 43:406-11. 2006
    ..05). Other ongoing trials will address not only whether CAS could be superior to CEA in high-risk patients but also, more importantly, whether CAS is beneficial in other subgroups, such as low-risk and asymptomatic patients...
  40. pmc Safety and efficacy of patient specific intramuscular injection of HGF plasmid gene therapy on limb perfusion and wound healing in patients with ischemic lower extremity ulceration: results of the HGF-0205 trial
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    J Vasc Surg 52:1525-30. 2010
    ..The purpose of this randomized placebo controlled multi-center trial was to further assess the safety and clinical efficacy of a modified HGF gene delivery technique in patients with CLI and no revascularization options...
  41. ncbi request reprint Regulation of vascular smooth muscle cell differentiation
    Eva M Rzucidlo
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Vasc Surg 45:A25-32. 2007
    ....
  42. ncbi request reprint Carotid artery stenting: what have we learned from the clinical trials and registries and where do we go from here?
    Philip P Goodney
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Ann Vasc Surg 22:148-58. 2008
    ..This report aims to provide a comprehensive and critical review of the trials and registries of CAS and to offer insight into future directions of this emerging technology...
  43. doi request reprint Functional outcomes following catheter-based iliac vein stent placement
    Courtney J Warner
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Vasc Endovascular Surg 47:331-4. 2013
    ..The purpose of this study was to determine midterm outcomes and functional quality of life among patients treated with iliac vein stenting...
  44. pmc Lesion complexity drives the cost of superficial femoral artery endovascular interventions
    Karen L Walker
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH
    J Vasc Surg 62:998-1002. 2015
    ..This study examined the association of lesion severity and cost of SFA stenting and to determine if procedure cost affects primary patency at 1 year...
  45. pmc Endovascular aneurysm repair delivery redesign leads to quality improvement and cost reduction
    Courtney J Warner
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 62:285-9. 2015
    ..We performed a comprehensive analysis of EVAR delivery at an academic medical center to identify targets for quality improvement and cost reduction in light of impending health care reform...
  46. pmc Outcomes of carotid endarterectomy versus stenting in comparable medical risk patients
    Emily L Spangler
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 60:1227-31, 1231.e1. 2014
    ..In medically high-risk patients the choice between carotid artery stenting (CAS) and carotid endarterectomy (CEA) can be difficult. The purpose of this study was to compare risk-stratified outcomes of CAS and CEA...
  47. ncbi request reprint Early results of external iliac artery stenting combined with common femoral artery endarterectomy
    Peter R Nelson
    Section of Vascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, Dartmouth Medical School, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 35:1107-13. 2002
    ..Surgical treatment for this disease distribution includes extensive endarterectomy or bypass procedures or both. We report our initial experience with a combined open and endovascular approach to these patients...
  48. doi request reprint Brain injury after carotid revascularization: outcomes, mechanisms, and opportunities for improvement
    Joshua B Goldberg
    Department of General Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Ann Vasc Surg 25:270-86. 2011
    ..We sought to perform a systematic review of neurologic injury after carotid revascularization to guide future quality improvement efforts focused on reducing potentially preventable events...
  49. ncbi request reprint Management of carotid injuries in a hostile neck using endovascular grafts
    Mark C Wyers
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, One Medical Center Drive, Lebanon, NH 03756, USA
    J Vasc Surg 39:1335-9. 2004
    ..In the second case, an endovascular graft was used to treat an intraoperative common carotid injury in a re-operated, radiated neck. These cases demonstrate the utility of endovascular graft treatment of emergent carotid injuries...
  50. ncbi request reprint Below-Knee Amputation Failure and Poor Functional Outcomes Are Higher Than Predicted in Contemporary Practice
    Jesse A Columbo
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Vasc Endovascular Surg . 2016
    ..This study sought to examine the contemporary clinical and functional outcomes of patients undergoing BKA in the endovascular era...
  51. doi request reprint The Prevalence and Regional Variation of Major Depressive Disorder Among Patients With Peripheral Arterial Disease in the Medicare Population
    Jesse A Columbo
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Vasc Endovascular Surg 50:235-40. 2016
    ..Data to support a similar association between peripheral arterial disease (PAD) and MDD are more limited. This study examines the prevalence and regional variation of both PAD and MDD in a large contemporary patient sample...
  52. pmc Physician specialty and variation in carotid revascularization technique selected for Medicare patients
    Jessica B Wallaert
    Division of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 63:89-97. 2016
    ..We hypothesized that the choice of CAS vs CEA varies as a function of treating physician specialty, which would result in regional variation in the relative use of these treatment types...
  53. doi request reprint Lean principles optimize on-time vascular surgery operating room starts and decrease resident work hours
    Courtney J Warner
    Department of Surgery, Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH Electronic address
    J Vasc Surg 58:1417-22. 2013
    ..These techniques are less commonly applied in health care. This study assessed the effectiveness of Lean principles on first case on-time operating room starts and quantified effects on resident work hours...
  54. doi request reprint Update on clinical trials evaluating the effect of biologic therapy in patients with critical limb ischemia
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Lebanon Medical Center, Lebanon, NH 03756 0001, USA
    J Vasc Surg 56:264-6. 2012
    ..Phase 3 trials are now in progress. This report summarizes the recent results of, and future plans for, gene and cellular therapy clinical trials in patients with CLI...
  55. ncbi request reprint The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation
    Kathleen A Martin
    Department of Surgery, Section of Vascular Surgery, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA
    Am J Physiol Cell Physiol 286:C507-17. 2004
    ..In conclusion, we report that regulation of VSMC differentiation is a novel function of the rapamycin-sensitive mTOR signaling pathway...
  56. ncbi request reprint A truncated plasminogen activator inhibitor-1 protein blocks the availability of heparin-binding vascular endothelial growth factor A isoforms
    Mary Jo Mulligan-Kehoe
    Department of Surgery, Vascular Surgery Section, Dartmouth Medical School, Dartmouth College, Hanover, New Hampshire 03756, USA
    J Biol Chem 277:49077-89. 2002
    ..This insight into anti-angiogenic functions related to PAI-1 conformational changes could provide potential intervention points in angiogenesis associated with atherosclerotic plaques and cancer...
  57. ncbi request reprint Multicenter Experience of Surgical Explantation of Carotid Stents for Recurrent Stenosis
    Jesse A Columbo
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
    Vasc Endovascular Surg . 2016
    ..The optimal management of symptomatic or severe ISR remains poorly defined. The purpose of this study was to describe the indications, treatment, and mid- to long-term outcomes of patients undergoing CAS explantation for ISR...
  58. doi request reprint Results of transcaval embolization for sac expansion from type II endoleaks after endovascular aneurysm repair
    Kristina A Giles
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH
    J Vasc Surg 61:1129-36. 2015
    ..Management of type II endoleaks after endovascular aneurysm repair can be problematic. This study reports our experience with a relatively novel strategy to treat this complication, transcaval coil embolization (TCCE) of the aneurysm sac...
  59. pmc Retrospective review of superficial femoral artery stenting in diabetic patients: thiazolidinedione use may decrease reinterventions
    Karen L Walker
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, 1 Medical Center Drive, Lebanon, NH 03756, USA
    BMC Cardiovasc Disord 14:184. 2014
    ..We hypothesize that diabetic patients taking thiazolidinediones at the time of primary superficial femoral artery (SFA) stenting have fewer reinterventions...
  60. ncbi request reprint The prostacyclin receptor induces human vascular smooth muscle cell differentiation via the protein kinase A pathway
    Kristina M Fetalvero
    Department of Pharmacology and Toxicology, Dartmouth Medical School, Lebanon, NH 03756, USA
    Am J Physiol Heart Circ Physiol 290:H1337-46. 2006
    ..This provides important mechanistic insights into the induction of cardiovascular events with the use of selective COX-2 inhibitors...
  61. pmc Bone marrow aspirate injection for treatment of critical limb ischemia with comparison to patients undergoing high-risk bypass grafts
    Kristina A Giles
    Section of Vascular and Endovascular Surgery, Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH
    J Vasc Surg 61:134-7. 2015
    ..Whereas clinical trials are ongoing, there are few comparative data to assess its efficacy compared with bypass...
  62. doi request reprint Update on biological therapies for critical limb ischemia
    Richard J Powell
    Section of Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Cardiol Clin 29:411-7. 2011
    ..Persistent obstacles exist with current study designs that complicate the ability to successfully perform clinical critical limb ischemia trials...
  63. pmc Acceleration of cardiovascular disease by a dysfunctional prostacyclin receptor mutation: potential implications for cyclooxygenase-2 inhibition
    Eric Arehart
    Department of Pharmacology and Toxicology, Dartmouth Hitchcock Medical Center, Hanover, NH 03755, USA
    Circ Res 102:986-93. 2008
    ..Combining both biochemical and clinical approaches, we conclude that diminished prostacyclin receptor signaling may contribute, in part, to the underlying adverse cardiovascular outcomes observed with cyclooxygenase-2 inhibition...
  64. ncbi request reprint The effect of endothelial cell overexpression of plasminogen activator inhibitor-1 on smooth muscle cell migration
    Richard R Proia
    Department of Surgery, Dartmouth Hitchcock Medical Center, Dartmouth Medical School, Lebanon, NH 03756, USA
    J Vasc Surg 36:164-71. 2002
    ..Plasminogen activator inhibitor-1 (PAI-1), a known inhibitor of plasminogen activators, may regulate smooth muscle cell migration (SMC) through alteration in matrix metalloproteinase (MMP) activity...
  65. ncbi request reprint Cost determinants of percutaneous and surgical interventions for treatment of intermittent claudication from the perspective of the hospital
    Bertrand Janne d'Othée
    Department of Radiology, Cardiovascular Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street GRB 290, Boston 02114 2696, USA
    Cardiovasc Intervent Radiol 31:56-65. 2008
    ..To identify pretreatment predictors of procedural costs in percutaneous and surgical interventions for intermittent claudication due to aortoiliac and/or femoropopliteal disease...
  66. ncbi request reprint Efficacy and safety of specific immunotherapy with SQ allergen extract in treatment-resistant seasonal allergic rhinoconjunctivitis
    Anthony J Frew
    Allergy and Inflammation Research Subdivision, School of Medicine, University of Southampton, UK
    J Allergy Clin Immunol 117:319-25. 2006
    ..Specific immunotherapy is widely used to treat allergic rhinitis, but few large-scale clinical trials have been performed...
  67. ncbi request reprint Role of ciclosporin in steroid-responsive sudden sensorineural hearing loss
    Lisha McClelland
    Department of Otolaryngology, Head and Neck Surgery, Queen s Medical Centre, Nottingham, UK
    Acta Otolaryngol 125:1356-60. 2005
    ..Long-term treatment with high-dose corticosteroids exposes patients to potentially serious adverse effects. Immunosuppression with ciclosporin can be an effective and well-tolerated treatment for steroid-responsive sudden SNHL...
  68. ncbi request reprint Infliximab in the treatment of refractory posterior uveitis
    Annie Joseph
    Department of Ophthalmology and Visual Sciences, B Floor, Eye and ENT Block, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Ophthalmology 110:1449-53. 2003
    ..To determine the efficacy and safety of infliximab in the treatment of refractory posterior uveitis...
  69. ncbi request reprint Behçet's syndrome: from aetiology to treatment
    Richard J Powell
    Department of Clinical Immunology, Queens Medical Centre, University of Nottingham, Nottingham, UK
    Adv Exp Med Biol 528:481-6. 2003
  70. ncbi request reprint The eye in systemic inflammatory diseases
    Peter McCluskey
    Department of Ophthalmology at St Vincent s Hospital and Royal Prince Alfred Hospital, Sydney, Australia
    Lancet 364:2125-33. 2004
    ....
  71. ncbi request reprint Heterogeneity among patients with tumor necrosis factor receptor-associated periodic syndrome phenotypes
    Ebun Aganna
    Barts and London, Queen Mary s School of Medicine and Dentistry, London, UK
    Arthritis Rheum 48:2632-44. 2003
    ..To investigate the prevalence of tumor necrosis factor receptor-associated periodic syndrome (TRAPS) among outpatients presenting with recurrent fevers and clinical features consistent with TRAPS...
  72. ncbi request reprint Simvastatin treatment for inflammatory attacks of the hyperimmunoglobulinemia D and periodic fever syndrome
    Anna Simon
    Department of General Internal Medicine, University Medical Center St Radboud, Nijmegen, The Netherlands
    Clin Pharmacol Ther 75:476-83. 2004
    ..These data offer preliminary evidence for the hypothesis that simvastatin may improve inflammatory attacks in the hyper-IgD syndrome. This highlights the anti-inflammatory properties of HMG-CoA reductase inhibition...