P Wang

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. ncbi request reprint Molecular structure of the peritrophic membrane (PM): identification of potential PM target sites for insect control
    P Wang
    Boyce Thompson Institute, Cornell University, Ithaca, New York 14853, USA
    Arch Insect Biochem Physiol 47:110-8. 2001
  2. ncbi request reprint Identification of two new peritrophic membrane proteins from larval Trichoplusia ni: structural characteristics and their functions in the protease rich insect gut
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 34:215-27. 2004
  3. pmc Mechanism of resistance to Bacillus thuringiensis toxin Cry1Ac in a greenhouse population of the cabbage looper, Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, Geneva, NY 14456, USA
    Appl Environ Microbiol 73:1199-207. 2007
  4. ncbi request reprint Characterization and cDNA cloning of midgut carboxypeptidases from Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva 14456, USA
    Insect Biochem Mol Biol 34:831-43. 2004
  5. ncbi request reprint Rapid and efficient isolation of highly specific antibodies from an antiserum against a pool of proteins
    P Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Biotech Histochem 78:201-5. 2003
  6. ncbi request reprint Molecular characterization of four midgut aminopeptidase N isozymes from the cabbage looper, Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 35:611-20. 2005
  7. ncbi request reprint A novel chitin-binding protein identified from the peritrophic membrane of the cabbage looper, Trichoplusia ni
    Wei Guo
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 35:1224-34. 2005
  8. ncbi request reprint Inheritance of resistance to Bacillus thuringiensis Cry1Ac toxin in a greenhouse-derived strain of cabbage looper (Lepidoptera: Noctuidae)
    Wendy C Kain
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    J Econ Entomol 97:2073-8. 2004
  9. doi request reprint Midgut cysteine protease-inhibiting activity in Trichoplusia ni protects the peritrophic membrane from degradation by plant cysteine proteases
    Changyou Li
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 39:726-34. 2009
  10. ncbi request reprint Primary and continuous midgut cell cultures from Pseudaletia unipuncta (Lepidoptera: Noctuidae)
    J J Garcia
    Boyce Thompson Institute for Plant Research, Cornell University. Ithaca, New York 14853, USA
    In Vitro Cell Dev Biol Anim 37:353-9. 2001

Collaborators

Detail Information

Publications65

  1. ncbi request reprint Molecular structure of the peritrophic membrane (PM): identification of potential PM target sites for insect control
    P Wang
    Boyce Thompson Institute, Cornell University, Ithaca, New York 14853, USA
    Arch Insect Biochem Physiol 47:110-8. 2001
    ....
  2. ncbi request reprint Identification of two new peritrophic membrane proteins from larval Trichoplusia ni: structural characteristics and their functions in the protease rich insect gut
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 34:215-27. 2004
    ..Alignment of the chitin binding sequences suggested that CBP1 and CBP2 evolved by gene duplication and the tandem chitin binding domains in the proteins arose from domain duplications...
  3. pmc Mechanism of resistance to Bacillus thuringiensis toxin Cry1Ac in a greenhouse population of the cabbage looper, Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, Geneva, NY 14456, USA
    Appl Environ Microbiol 73:1199-207. 2007
    ..ni population. Therefore, it is concluded that the mechanism for the greenhouse-evolved Cry1Ac resistance in T. ni is an alteration affecting the binding of Cry1Ab and Cry1Ac to the Cry1Ab/Cry1Ac binding site in the midgut...
  4. ncbi request reprint Characterization and cDNA cloning of midgut carboxypeptidases from Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva 14456, USA
    Insect Biochem Mol Biol 34:831-43. 2004
    ..The other two cDNAs are highly similar to carboxypeptidase A and carboxypeptidase B in sequences, but their activity was not predictable...
  5. ncbi request reprint Rapid and efficient isolation of highly specific antibodies from an antiserum against a pool of proteins
    P Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Biotech Histochem 78:201-5. 2003
    ..coli lysate of the IIM cDNA clone. This procedure allows rapid and efficient isolation of target protein specific antibodies from a polyclonal antiserum made against a pool of antigens...
  6. ncbi request reprint Molecular characterization of four midgut aminopeptidase N isozymes from the cabbage looper, Trichoplusia ni
    Ping Wang
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 35:611-20. 2005
    ....
  7. ncbi request reprint A novel chitin-binding protein identified from the peritrophic membrane of the cabbage looper, Trichoplusia ni
    Wei Guo
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 35:1224-34. 2005
    ..The sequence characteristics of TnPM-P42 indicate that TnPM-P42 represents a novel family of insect proteins. However, its biochemical and physiological functions require further investigation...
  8. ncbi request reprint Inheritance of resistance to Bacillus thuringiensis Cry1Ac toxin in a greenhouse-derived strain of cabbage looper (Lepidoptera: Noctuidae)
    Wendy C Kain
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    J Econ Entomol 97:2073-8. 2004
    ..Therefore, we conclude that the inheritance of the resistance to Cry1Ac in the T. ni larvae is monogenic...
  9. doi request reprint Midgut cysteine protease-inhibiting activity in Trichoplusia ni protects the peritrophic membrane from degradation by plant cysteine proteases
    Changyou Li
    Department of Entomology, Cornell University, New York State Agricultural Experiment Station, Geneva, NY 14456, USA
    Insect Biochem Mol Biol 39:726-34. 2009
    ..However, the biochemical identity of the cysteine protease-inhibiting activity in midgut fluid has yet to be identified...
  10. ncbi request reprint Primary and continuous midgut cell cultures from Pseudaletia unipuncta (Lepidoptera: Noctuidae)
    J J Garcia
    Boyce Thompson Institute for Plant Research, Cornell University. Ithaca, New York 14853, USA
    In Vitro Cell Dev Biol Anim 37:353-9. 2001
    ..Infection of these cells with multiply embedded nucleopolyhedrovirus was confirmed, and we conclude that these midgut cells can be used as an in vitro model system to study early events in baculovirus infection...
  11. pmc Characterization of chimeric Bacillus thuringiensis Vip3 toxins
    Jun Fang
    Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310029, China
    Appl Environ Microbiol 73:956-61. 2007
    ..thuringiensis Cry1A proteins and Vip3A toxins. The results in this study demonstrated that vip3Ac1 and its chimeric vip3 genes can be excellent candidates for engineering a new generation of transgenic plants for insect pest control...
  12. pmc Functional identification of orthologous genes encoding pterin recycling activity in Plasmodium falciparum and Toxoplasma gondii
    Qi Wang
    Faculty of Life Sciences, University of Manchester, Jackson s Mill, P O Box 88, Manchester M60 1QD, United Kingdom
    Mol Biochem Parasitol 146:109-12. 2006
  13. ncbi request reprint The suppressor of cytokine signaling (SOCS)-7 interacts with the actin cytoskeleton through vinexin
    Nele Martens
    Neuroendocrine Immunology Group, Pharmacology Department, Medical School, Free University of Brussels VUB, 1090, Belgium
    Exp Cell Res 298:239-48. 2004
    ..Taken together, our data indicate that SOCS-7 interacts with vinexin and the actin cytoskeleton...
  14. ncbi request reprint Isolation of monomeric human V(H)s by a phage selection
    Rebecca To
    Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada
    J Biol Chem 280:41395-403. 2005
    ..These 15 V(H)s should serve as good scaffolds for developing immunotherapeutics, and the selection method employed here should have general utility for isolating proteins with desirable biophysical properties...
  15. ncbi request reprint Mint-3 regulates the retrieval of the internalized membrane-type matrix metalloproteinase, MT5-MMP, to the plasma membrane by binding to its carboxyl end motif EWV
    Ping Wang
    Department of Pharmacology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA
    J Biol Chem 279:20461-70. 2004
    ..Furthermore, Mint-3 significantly increased the level of MT5-MMP on the cell surface without affecting its synthesis and internalization. Therefore, Mints may be the adaptor proteins that regulate the trafficking of MT-MMPs...
  16. ncbi request reprint Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network
    Ping Wang
    Department of Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Biol Chem 279:15434-40. 2004
    ..These results indicate that the activation mechanism for ADAMTS4 can be targeted for therapeutical intervention against this enzyme...
  17. pmc Inheritance of resistance to Bacillus thuringiensis subsp. kurstaki in Trichoplusia ni
    Alida F Janmaat
    Department of Zoology, University of British Columbia, 6270 University Blvd, Vancouver, British Columbia, Canada V6T 1Z4
    Appl Environ Microbiol 70:5859-67. 2004
    ..This finding suggests that resistance to B. thuringiensis subsp. kurstaki in this T. ni population is due to more than one gene...
  18. pmc Synaptotagmin VII is targeted to secretory organelles in PC12 cells, where it functions as a high-affinity calcium sensor
    Ping Wang
    Department of Physiology, University of Wisconsin, 1300 University Ave, SMI 129, Madison, WI 53706, USA
    Mol Cell Biol 25:8693-702. 2005
    ..These data support the hypothesis that the complement of syt's expressed by a cell, in conjunction with their metal affinity, determines the divalent cation sensitivity of exocytosis...
  19. ncbi request reprint Mutations in the effector binding loops in the C2A and C2B domains of synaptotagmin I disrupt exocytosis in a nonadditive manner
    Ping Wang
    Department of Physiology, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA
    J Biol Chem 278:47030-7. 2003
    ..These findings indicate that the tandem C2 domains of syt cooperate with one another to trigger release via loop-mediated electrostatic interactions with effector molecules...
  20. ncbi request reprint [Synthesis, cloning, expression and antigenicity of the therapeutic multi-epitope gene of hepatitis B virus and of its products]
    Li Min Luo
    Institute of Tropic Diseases, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 23:802-5. 2003
    ..To study the synthesis, cloning, expression and antigenicity of therapeutic multi-epitope gene of hepatitis B virus...
  21. ncbi request reprint Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex
    Ning Zheng
    Cellular Biochemistry and Biophysics Program, Memorial Sloan Kettering Cancer Center, New York 10021, USA
    Nature 416:703-9. 2002
    ..The structure suggests that Cul1 may contribute to catalysis through the positioning of the substrate and the ubiquitin-conjugating enzyme, and this model is supported by Cul1 mutations designed to eliminate the rigidity of the scaffold...
  22. ncbi request reprint The anti-inflammatory effect of curcumin in an experimental model of sepsis is mediated by up-regulation of peroxisome proliferator-activated receptor-gamma
    Aqeel M Siddiqui
    Department of Surgery, North Shore University Hospital and Long Island Jewish Medical Center, Manhasset, New York, USA
    Crit Care Med 34:1874-82. 2006
    ..The purpose of this study was to demonstrate whether curcumin protects septic animals and, if so, whether activation of peroxisome proliferator-activated receptor (PPAR)-gamma, an anti-inflammatory nuclear receptor, plays any role...
  23. pmc Breast milk lactoferrin regulates gene expression by binding bacterial DNA CpG motifs but not genomic DNA promoters in model intestinal cells
    Peter Mulligan
    Adult and Paediatric Gastroenterology, Institute of Cell and Molecular Science, Barts and The London, Queen Mary s School of Medicine and Dentistry, London E1 2AD, United Kingdom
    Pediatr Res 59:656-61. 2006
    ..We conclude that breast milk LF regulates gene expression by binding CpG motifs extracellularly, with follicular B cells in the infant intestine a likely target...
  24. ncbi request reprint [Screening and preliminary identification of mimetic peptides of Plasmodium falciparum-infected erythrocyte membrane surface protein 1]
    Wen bo Hao
    Tropical Disease Department, The Southern Medical University, Guangzhou 510515, China
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 23:388-91. 2005
    ..To screen and identify mimetic peptides of Plasmodium falciparun-infected erythrocyte membrane surface protein 1 in order to explore anti-adhesive agent against cerebral malaria...
  25. ncbi request reprint Study of correlation between expression of bradykinin B2 receptor and pathological grade in human gliomas
    Yisong Zhao
    Department of Neurobiology, China Medical University, Shenyang, Liaoming Province, Peoples Republic of China
    Br J Neurosurg 19:322-6. 2005
    ..Determination of bradykinin B(2) receptor expression level in human glioma may be useful in screening glioma patients to predict whether they will be suitable for opening of the blood - tumour barrier with bradykinin or its analogue...
  26. pmc Structure dissection of human progranulin identifies well-folded granulin/epithelin modules with unique functional activities
    Dmitri Tolkatchev
    Bio NMR and Protein Research Laboratory, Biotechnology Research Institute, National Research Council of Canada, Montreal, Quebec H4P 2R2, Canada
    Protein Sci 17:711-24. 2008
    ..The functionally active and structurally well-characterized human hGrnA offers a unique opportunity for detailed structure-function studies of these important GEM proteins as novel members of mammalian growth factors...
  27. pmc The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis
    Haichao Wang
    Department of Emergency Medicine, North Shore University Hospital, New York University School of Medicine, Manhasset, NY 11030, USA
    J Nutr 136:360-5. 2006
    ..sinensis contains water-soluble components that exert protective effects against lethal endotoxemia and experimental sepsis in part by attenuating systemic accumulation of a late proinflammatory cytokine, HMGB1...
  28. ncbi request reprint Gib2, a novel Gbeta-like/RACK1 homolog, functions as a Gbeta subunit in cAMP signaling and is essential in Cryptococcus neoformans
    Daniel A Palmer
    Research Institute for Children, Department of Pediatrics, Louisiana State University Health Sciences Center, 200 Henry Clay Avenue, New Orleans, LA 70118, USA
    J Biol Chem 281:32596-605. 2006
    ..Finally, Gib2 is shown to also physically interact with a downstream target of Gpa1-cAMP signaling, Smg1, and the protein kinase C homolog Pkc1, indicating that Gib2 is also a multifunctional RACK1-like protein...
  29. doi request reprint Characterization of cDNAs associated with lignification and their expression profiles in loquat fruit with different lignin accumulation
    Lan Lan Shan
    Zhejiang University, Huajiachi Campus, 310029, Hangzhou, China
    Planta 227:1243-54. 2008
    ..Our integrated data on lignin, monolignol precursors, and associated enzymes and genes, provide a consistent model of fruit lignification...
  30. pmc Sensing Escherichia coli O157:H7 via frequency shift through a self-assembled monolayer based QCM immunosensor
    Li jiang Wang
    Biosensor National Special Laboratory, Key Laboratory of Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China
    J Zhejiang Univ Sci B 9:121-31. 2008
    ..coli O157:H7. In order to reduce the fabrication time, a polyelectrolyte layer-by-layer self-assembly (LBL-SA) method was adopted for fast construction. Finally, the reproducibility of this biosensor was discussed...
  31. doi request reprint Activation of Jun N-terminal kinase is a mediator of vincristine-induced apoptosis of melanoma cells
    Bi Ke Zhu
    Immunology and Oncology Unit, Royal Newcastle Hospital, University of Newcastle, Newcastle, New South Wales, Australia
    Anticancer Drugs 19:189-200. 2008
    ..The results are consistent with the phosphorylation of Bcl-2 protein, resulting in the activation of Bax/Bak, release of cytochrome c from the mitochondria and the resulting activation of caspases...
  32. ncbi request reprint Preparation for aflatoxin B(1)-cationized bovine serum albumin based on Mannich-type reaction
    Youxiang Zhou
    College of Food Science and Technology, Huazhong Agricultural University, Wuhan, China
    J Immunol Methods 328:79-88. 2007
    ..This suggests that the Mannich-type reaction might be an alternative method of preparation for AFB(1)-protein...
  33. ncbi request reprint Conformational analyses of a partially-folded bioactive prodomain of human furin
    Surajit Bhattacharjya
    Biomolecular NMR and Protein Research Laboratory, Biotechnology Research Institute, National Research Council of Canada, 6100 Royalmount Avenue, Montreal, Quebec, Canada
    Biopolymers 86:329-44. 2007
    ..As such, this study provides valuable insights into the structural properties of the furin prodomain in relation to its role in the folding of the furin zymogen and its inhibitory action toward furin...
  34. ncbi request reprint Chinese yellow wine inhibits production of homocysteine-induced extracellular matrix metalloproteinase-2 in cultured rat vascular smooth muscle cells
    Hangyuan Guo
    Department of Cardiology, Shaoxing People s Hospital The First Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang 312000, China
    Clin Nutr 26:348-54. 2007
    ..The present research aimed to study the effects of Chinese yellow wine on the production of homocysteine (Hcy)-induced extracellular MMP-2 in cultured rats vascular smooth muscle cells (VSMCs)...
  35. pmc Adrenomedullin and adrenomedullin binding protein-1 protect endothelium-dependent vascular relaxation in sepsis
    Mian Zhou
    Department of Surgery, North Shore University Hospital and Long Island Jewish Medical Center, and The Feinstein Institute for Medical Research, Manhasset, New York 11030, USA
    Mol Med 13:488-94. 2007
    ....
  36. ncbi request reprint Endotoxin downregulates peroxisome proliferator-activated receptor-gamma via the increase in TNF-alpha release
    Mian Zhou
    Department of Surgery, North Shore University Hospital and Long Island Jewish Medical Center and The Feinstein Institute for Medical Research, Manhasset, NY 11030, USA
    Am J Physiol Regul Integr Comp Physiol 294:R84-92. 2008
    ..We, therefore, conclude that LPS downregulates PPAR-gamma expression during sepsis via an increase in TNF-alpha release...
  37. pmc Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice
    Zhenglong Wang
    Program for Vascular Biology and Therapeutics and Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06520 8066, USA
    J Clin Invest 118:195-204. 2008
    ..These results demonstrate what we believe to be a novel role for PLC activity in promoting macrophage survival in atherosclerotic plaques and identify PLC beta3 as a potential target for treatment of atherosclerosis...
  38. pmc An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites
    Sabine Dittrich
    Manchester Interdisciplinary Biocentre, Faculty of Life Sciences, University of Manchester, 131 Princess Street, Manchester M1 7DN, UK
    Mol Microbiol 67:609-18. 2008
    ....
  39. pmc Role of protein O-mannosyltransferase Pmt4 in the morphogenesis and virulence of Cryptococcus neoformans
    Gillian M Olson
    Department of Microbiology and Immunology, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    Eukaryot Cell 6:222-34. 2007
    ..Taken together, these results indicate a central role for Pmt4-mediated protein O mannosylation in growth, cell wall integrity, and virulence of C. neoformans...
  40. ncbi request reprint Biodecolorization of azo dye acid red B under high salinity condition
    M Salah Uddin
    School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, China
    Bull Environ Contam Toxicol 79:440-4. 2007
    ..On the other hand, strain grown in very low, or high concentrations, of salt did not show good performance in decolorization; suggesting that salt concentrations in the surroundings control the production of azo reductase...
  41. ncbi request reprint [Preparation and characterization of anti-human IL-15 monoclonal antibody]
    Ping Wang
    Department of Immunology, Institute of Basic Medical Sciences, Hebei Medical University, Shijiazhuang 050017, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:183-5. 2004
    ..To prepare monoclonal antibody (mAb) against human interleukin-15 (hIL-15) and identify its characterization...
  42. ncbi request reprint Gene expression profiling in INS-1 cells overexpressing thioredoxin-interacting protein
    Alexandra H Minn
    Department of Medicine, University of Wisconsin Madison, WI, USA
    Biochem Biophys Res Commun 336:770-8. 2005
    ..Thus, aside from regulating the cellular redox, TXNIP does modulate overall gene transcription and thereby may further enhance beta-cell death and impair insulin secretion...
  43. ncbi request reprint Differential activation of signal transducer and activator of transcription (STAT)3 and STAT5 and induction of suppressors of cytokine signalling in T(h)1 and T(h)2 cells
    Per Anderson
    Institute of Cell and Molecular Sciences, Barts and the London School of Medicine and Dentistry, London EC1A 7ED, UK
    Int Immunol 15:1309-17. 2003
    ..Our results suggests that STAT3 and STAT5, possibly regulated by the SOCS proteins, may play a role in the differentiation of T(h) cells, and in the maintenance of the T(h)1 and T(h)2 phenotype...
  44. ncbi request reprint [The roles of Smad 2/3 in transforming growth factor-beta 1 signaling in human dental pulp cells]
    Liu yu Bao
    Department of Operative Dentistry, College of Stomatology, The Fourth Military Medical University, Xi an 710032, China
    Zhonghua Kou Qiang Yi Xue Za Zhi 38:39-42. 2003
    ..To explore the roles of Smad 2/3 in transforming growth factor-beta(1) (TGF-beta(1)) signaling by human dental pulp cells...
  45. ncbi request reprint Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
    Jia fu Long
    Department of Biochemistry, Molecular Neuroscience Center, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, People s Republic of China
    J Mol Biol 327:203-14. 2003
    ..4 potassium channels in heterologous cells. The data presented provide a molecular basis for preferential binding of PSD-95 to multimeric membrane proteins with appropriate C-terminal sequences...
  46. ncbi request reprint [Identification of the binding site on ICAM-1 for red blood cells infected by Plasmodium falciparum]
    Wen bo Hao
    Institute of Tropical Medicine, The First Military Medical University, Guangzhou 510515
    Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 20:129-32. 2002
    ..To identify the binding site on ICAM-1 to PRBCs in order to explore anti-adhesive agent against cerebral malaria...
  47. ncbi request reprint Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus
    Ping Wang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People s Republic of China
    J Biol Chem 278:11648-53. 2003
    ....
  48. ncbi request reprint Adipocytokines, body composition, and fitness in children
    Dan Nemet
    Department of Pediatrics, Center for the Study of Health Effects of Exercise in Children, University of California, Irvine, California 92868, U S A
    Pediatr Res 53:148-52. 2003
    ..The novel data on adiponectin suggest that deleterious dysregulation of adipocytokines associated with obesity may occur relatively early in life...
  49. pmc Mating-type-specific and nonspecific PAK kinases play shared and divergent roles in Cryptococcus neoformans
    Ping Wang
    Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Eukaryot Cell 1:257-72. 2002
    ....
  50. ncbi request reprint [Application of phage antibody library technology: problems and their solutions]
    Yun xia Hou
    Laboratory of Tropical Diseases, Department of Tropical Medicine, First Military Medical University, Guangzhou 510515, China
    Di Yi Jun Yi Da Xue Xue Bao 22:366-8. 2002
    ..The authors conducted an analysis of these problems and thereby proposes their solutions...
  51. ncbi request reprint Amino-terminal fragment of urokinase-type plasminogen activator inhibits its plasminogen activation
    Ziyong Sun
    Institute of Molecular Medicine, Nanjing University, Nanjing 210093, PR China
    Thromb Res 106:105-11. 2002
    ....
  52. ncbi request reprint The role of endotoxin, TNF-alpha, and IL-6 in inducing the state of growth hormone insensitivity
    Ping Wang
    Research Institute of General Surgery, Jinling Hospital, 305 Zhong Shan East Road, Nanjing 210002, Jiangsu Province, China
    World J Gastroenterol 8:531-6. 2002
    ..The objective of this current study was to investigate the role of endotoxin, TNF-alpha and IL-6 in inducing the growth hormone insensitivity at the receptor and post-receptor levels...
  53. ncbi request reprint Nickel(II) and cobalt(II) complexes of hydroxyl-substituted triazamacrocyclic ligand as potential antitumor agents
    Feng Liang
    Department of Chemistry, Wuhan University, Wuhan 430072, Peoples Republic of China
    Bioorg Med Chem Lett 14:1901-4. 2004
    ....
  54. ncbi request reprint Insulin induces SOCS-6 expression and its binding to the p85 monomer of phosphoinositide 3-kinase, resulting in improvement in glucose metabolism
    Li Li
    Immunology Group, Institute of Cell and Molecular Sciences, St Barts and The Royal London School of Medicine, 59 Bartholomew s Close, London EC1A 7ED, United Kingdom
    J Biol Chem 279:34107-14. 2004
    ..Therefore, our results indicate that SOCS-6 may provide a dynamically regulated mechanism by which insulin can transiently overcome the negative effects that p85 monomers have on signaling via PI 3-kinase-dependent signaling pathways...
  55. ncbi request reprint Inhibition of vascular permeability factor/vascular endothelial growth factor-mediated angiogenesis by the Kruppel-like factor KLF2
    Resham Bhattacharya
    Program in Cardiovascular Transcriptional Biology, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Biol Chem 280:28848-51. 2005
    ..This effect is due to a potent inhibition of VEGFR2/KDR expression and promoter activity. These observations identify KLF2 as a regulator of VEGFR2/KDR and provide a foundation for novel approaches to regulate angiogenesis...
  56. ncbi request reprint Oxidized and ubiquitinated proteins may predict recovery of postischemic cardiac function: essential role of the proteasome
    Saul R Powell
    Department of Medicine, Long Island Jewish Medical Center Campus of the Albert Einstein College of Medicine, New Hyde Park, NY 11042, USA
    Antioxid Redox Signal 7:538-46. 2005
    ....
  57. pmc A molecular link between FGF and Dpp signaling in branch-specific migration of the Drosophila trachea
    Monn Monn Myat
    Department of Cell Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Dev Biol 281:38-52. 2005
    ..These studies support a model in which both the Dpp- and the FGF-signaling pathways control expression of knirps and knirps-related, thereby regulating cell migration during dorsal branch formation...
  58. ncbi request reprint Suppression of HMGB1 release by stearoyl lysophosphatidylcholine:an additional mechanism for its therapeutic effects in experimental sepsis
    Guoqian Chen
    Department of Emergency Medicine, North Shore University Hospital, New York University School of Medicine, Manhasset, NY 11030, USA
    J Lipid Res 46:623-7. 2005
    ..Thus, stearoyl LPC confers protection against lethal experimental sepsis partly by facilitating the elimination of the invading pathogens and partly by inhibiting endotoxin-induced release of a late proinflammatory cytokine, HMGB1...
  59. ncbi request reprint Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2
    Ping Wang
    Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, People s Republic of China
    J Biol Chem 278:6363-70. 2003
    ..Our study thus suggests that beta-arrestin 2 may serve as a cross-talk linker between GPCR and p53 signaling pathways...
  60. ncbi request reprint IL-2 overcomes the unresponsiveness but fails to reverse the regulatory function of antigen-induced T regulatory cells
    Per O Anderson
    Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London EC1A 7ED, United Kingdom
    J Immunol 174:310-9. 2005
    ....
  61. ncbi request reprint The hemopexin domain of membrane-type matrix metalloproteinase-1 (MT1-MMP) Is not required for its activation of proMMP2 on cell surface but is essential for MT1-MMP-mediated invasion in three-dimensional type I collagen
    Ping Wang
    Department of Pharmacology, University of Minnesota School of Medicine, Minneapolis, Minnesota 55455, USA
    J Biol Chem 279:51148-55. 2004
    ....
  62. ncbi request reprint Enzymatic degradation of trichloroethylene using enzyme extracts isolated from a bacterial consortium
    Bilal El-Zahab
    Department of Chemical Engineering, 301 Whitby Hall, The University of Akron, Akron, OH 44325 3906, USA
    Appl Biochem Biotechnol 117:165-74. 2004
    ..The observations with NADH were in agreement with the assumption that toluene monooxygenases (which are NADH dependent) are the key enzymes for the degradation reactions...
  63. ncbi request reprint Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum
    Ping Wang
    Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, P O Box 88, Manchester M60 1QD, UK
    Mol Biochem Parasitol 135:77-87. 2004
    ..This would mirror earlier studies indicating that the DHFR activity of HB3 is also compromised relative to other variants...
  64. ncbi request reprint A Drosophila temperature-sensitive seizure mutant in phosphoglycerate kinase disrupts ATP generation and alters synaptic function
    Ping Wang
    The Picower Center for Learning and Memory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
    J Neurosci 24:4518-29. 2004
    ..Given the behavioral similarities between disruptions of PGK function in Drosophila and humans, the analysis of nubian animals may reveal conserved neuronal responses associated with altered ATP generation within the brain...
  65. ncbi request reprint Mechanism of growth hormone insensitivity induced by endotoxin
    Ping Wang
    Medical College of Nanjing University, Reseach Institute of General Surgery, Jinling Hospital, Nanjing 210002, China
    Acta Pharmacol Sin 23:16-22. 2002
    ..To investigate the mechanism of growth hormone (GH) insensitivity induced by endotoxin at receptor and post-receptor levels...