ENRIQUE J RODRIGUEZ BOULAN

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1
    Erwin de la Fuente-Ortega
    Dyson Vision Research Institute, Department of Ophthalmology, Weill Cornell Medical College, New York, NY 10065
    Mol Biol Cell 26:1728-42. 2015
  2. pmc Response: the "tail" of the twin adaptors
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA Electronic address
    Dev Cell 27:247-8. 2013
  3. ncbi Epithelial trafficking: new routes to familiar places
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Ave, New York, New York 10021, USA
    Curr Opin Cell Biol 16:436-42. 2004
  4. ncbi Organization of vesicular trafficking in epithelia
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10021, USA
    Nat Rev Mol Cell Biol 6:233-47. 2005
  5. ncbi Protein sorting in the Golgi complex: shifting paradigms
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, LC 300, 1300 York Avenue, New York, NY 10021, USA
    Biochim Biophys Acta 1744:455-64. 2005
  6. pmc Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells
    Fanny Jaulin
    Department of Cell and Developmental Biology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10021, USA
    Dev Cell 13:511-22. 2007
  7. ncbi The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane
    Yunbo Gan
    Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Ave, New York, NY 10021, USA
    Nat Cell Biol 4:605-9. 2002
  8. pmc LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network
    Susana B Salvarezza
    Margaret Dyson Vision Research Institute and Department of Cell and Developmental Biology, HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, NY 10065, USA
    Mol Biol Cell 20:438-51. 2009
  9. pmc Clathrin is a key regulator of basolateral polarity
    Sylvie Deborde
    Department of Ophthalmology, Dyson Vision Research Institute, LC 300, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA
    Nature 452:719-23. 2008
  10. pmc AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells
    Diego Gravotta
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:1564-9. 2007

Collaborators

Detail Information

Publications22

  1. pmc Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1
    Erwin de la Fuente-Ortega
    Dyson Vision Research Institute, Department of Ophthalmology, Weill Cornell Medical College, New York, NY 10065
    Mol Biol Cell 26:1728-42. 2015
    ....
  2. pmc Response: the "tail" of the twin adaptors
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Cornell Medical College, New York, NY 10065, USA Electronic address
    Dev Cell 27:247-8. 2013
    ..Here, Rodriguez-Boulan et al. suggest that the available evidence remains consistent with subcellular compartment-specific distinctions in μ1 paralog functions. ..
  3. ncbi Epithelial trafficking: new routes to familiar places
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Ave, New York, New York 10021, USA
    Curr Opin Cell Biol 16:436-42. 2004
    ..A promising area of research is the study of trafficking functions of novel polarity genes identified in Drosophila and Caenorhabditis elegans...
  4. ncbi Organization of vesicular trafficking in epithelia
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10021, USA
    Nat Rev Mol Cell Biol 6:233-47. 2005
    ..Recent live-cell-imaging studies provide a real-time view of sorting processes in epithelial cells, including key roles for actin, microtubules and motors in the organization of post-Golgi trafficking...
  5. ncbi Protein sorting in the Golgi complex: shifting paradigms
    Enrique Rodriguez-Boulan
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, LC 300, 1300 York Avenue, New York, NY 10021, USA
    Biochim Biophys Acta 1744:455-64. 2005
    ..Several adaptors are candidates to sort apical and basolateral proteins but only AP1B and AP4 are currently involved. Progress is fast and future work should elucidate many of the open questions...
  6. pmc Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells
    Fanny Jaulin
    Department of Cell and Developmental Biology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10021, USA
    Dev Cell 13:511-22. 2007
    ..Our results demonstrate that apical protein transport depends on selective microtubule motors and that epithelial cells switch kinesins for post-Golgi transport during acquisition of polarity...
  7. ncbi The epithelial-specific adaptor AP1B mediates post-endocytic recycling to the basolateral membrane
    Yunbo Gan
    Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Ave, New York, NY 10021, USA
    Nat Cell Biol 4:605-9. 2002
    ..Targeting and recycling assays in LLC-PK1 cells, before and after transfection with mu 1B, and in MDCK cells, which express mu 1B constitutively, suggest that AP1B sorts basolateral proteins post-endocytically...
  8. pmc LIM kinase 1 and cofilin regulate actin filament population required for dynamin-dependent apical carrier fission from the trans-Golgi network
    Susana B Salvarezza
    Margaret Dyson Vision Research Institute and Department of Cell and Developmental Biology, HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Medical College of Cornell University, New York, NY 10065, USA
    Mol Biol Cell 20:438-51. 2009
    ....
  9. pmc Clathrin is a key regulator of basolateral polarity
    Sylvie Deborde
    Department of Ophthalmology, Dyson Vision Research Institute, LC 300, Weill Medical College of Cornell University, 1300 York Avenue, New York, New York 10065, USA
    Nature 452:719-23. 2008
    ..Our results demonstrate a broad requirement for clathrin in basolateral protein trafficking in epithelial cells...
  10. pmc AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells
    Diego Gravotta
    Margaret Dyson Vision Research Institute, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 104:1564-9. 2007
    ..TfR utilizes a direct route from Golgi to basolateral membrane that is established as the epithelial monolayer matures...
  11. pmc Par-1 promotes a hepatic mode of apical protein trafficking in MDCK cells
    David Cohen
    Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 101:13792-7. 2004
    ..To our knowledge, Par-1 is the first gene assigned to this task in epithelial morphogenesis...
  12. pmc Clathrin adaptor AP1B controls adenovirus infectivity of epithelial cells
    Fernando Diaz
    Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10065, USA
    Proc Natl Acad Sci U S A 106:11143-8. 2009
    ....
  13. pmc Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells
    Anne Müsch
    M Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, NY 10021, USA
    Mol Biol Cell 13:158-68. 2002
    ..These data suggest that Mlgl contributes to apico-basolateral polarity by regulating basolateral exocytosis...
  14. pmc Itinerant exosomes: emerging roles in cell and tissue polarity
    Aparna Lakkaraju
    Margaret M Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Trends Cell Biol 18:199-209. 2008
    ..In this review, we discuss new evidence suggesting that exosomes participate in the transport of morphogens and RNA, and thus influence cell polarity and developmental patterning of tissues...
  15. pmc The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium
    Ami A Deora
    Margaret M Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Mol Biol Cell 15:4148-65. 2004
    ..This unusual basolateral sorting signal will be useful in unraveling the specialized sorting machinery of RPE cells...
  16. ncbi Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells
    Geri Kreitzer
    Margaret M Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, NY 10021, USA
    Nat Cell Biol 5:126-36. 2003
    ....
  17. pmc The absence of a clathrin adapter confers unique polarity essential to proximal tubule function
    Ryan Schreiner
    Department of Ophthalmology, Dyson Vision Research Institute, Weill Medical College, Cornell University, New York, New York, USA
    Kidney Int 78:382-8. 2010
    ..Hence, our results show that differential expression of AP1B contributes to normal kidney function and illustrates possible roles of this adapter protein in kidney development, physiology, and pathology...
  18. ncbi Estrogen lowers Alzheimer beta-amyloid generation by stimulating trans-Golgi network vesicle biogenesis
    Jeffrey P Greenfield
    Fisher Center for Research on Alzheimer s Disease and Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York 10021, USA
    J Biol Chem 277:12128-36. 2002
    ..These results suggest a novel mechanism through which 17beta-E2 may act in estrogen-responsive tissues and illustrate how altering the kinetics of the transport of a protein can influence its metabolic fate...
  19. pmc Regulatory dissociation of Tctex-1 light chain from dynein complex is essential for the apical delivery of rhodopsin
    Ting Yu Yeh
    Department of Ophthalmology, Weill Medical College of Cornell University, 1300 York Avenue, New York, NY 10021, USA
    Traffic 7:1495-502. 2006
    ..Taken together, these results suggest that the dynein complex disassembles to release cargo due to the specific phosphorylation of Tctex-1 at the S82 residue and that this process is critical for the apical delivery of membrane cargoes...
  20. pmc Efficient electroporation of DNA and protein into confluent and differentiated epithelial cells in culture
    Ami A Deora
    Margaret M Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    Traffic 8:1304-12. 2007
    ..We report here the development of a simple procedure that uses available commercial equipment and works efficiently and reproducibly for a variety of epithelial cell lines in culture...
  21. pmc It takes two to tango to the melanosome
    Aparna Lakkaraju
    Margaret M Dyson Vision Research Institute, Weill Medical College, Cornell University, New York, NY 10065, USA
    J Cell Biol 187:161-3. 2009
    ..1083/jcb.200907122) show that a close interaction between the clathrin adaptor AP-1 and a kinesin motor KIF13A is essential for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes and for organelle biogenesis...