Marie A Caudill

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Maternal obesity disrupts the methionine cycle in baboon pregnancy
    Peter W Nathanielsz
    Center for Pregnancy and Newborn Research, Department OB GYN, University of Texas Health Science Center San Antonio, San Antonio, Texas Texas Center for Pregnancy and Life Course Health, Southwest National Primate Research Institute Texas Biomedical Research Institute, San Antonio, Texas
    Physiol Rep 3:. 2015
  2. pmc Plasma choline metabolites associate with metabolic stress among young overweight men in a genotype-specific manner
    J Yan
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Nutr Diabetes 2:e49. 2012
  3. pmc Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype
    Marie A Caudill
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY 14853, USA
    J Nutr 139:727-33. 2009
  4. pmc Folate bioavailability: implications for establishing dietary recommendations and optimizing status
    Marie A Caudill
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 91:1455S-1460S. 2010
  5. doi request reprint Pre- and postnatal health: evidence of increased choline needs
    Marie A Caudill
    Cornell University, Division of Nutritional Sciences, 228 Savage Hall, Ithaca, NY, USA
    J Am Diet Assoc 110:1198-206. 2010
  6. doi request reprint Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women
    Jian Yan
    Division of Nutritional Sciences, Cornell University, Ithaca, NY JY, XJ, AAW, OVM, JTB, and MAC the Family and Consumer Sciences Nutrition, Shepherd University, Shepherdstown, WV CAP the Department of Medicine and Division of Hematology, University of Colorado School of Medicine, Aurora, CO SPS and RHA and the Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL JFG
    Am J Clin Nutr 98:1459-67. 2013
  7. doi request reprint A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1)
    Xinyin Jiang
    Division of Nutritional Sciences, Cornell University, 228 Savage Hall, Ithaca, NY 14853, USA
    FASEB J 27:1245-53. 2013
  8. doi request reprint Choline inadequacy impairs trophoblast function and vascularization in cultured human placental trophoblasts
    Xinyin Jiang
    Division of Nutritional Science, Cornell University, Ithaca, New York
    J Cell Physiol 229:1016-27. 2014
  9. pmc Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration
    Martha S Field
    Division of Nutritional Science, Cornell University, Ithaca, NY, USA
    J Nutr 143:41-5. 2013
  10. doi request reprint Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans
    Xinyin Jiang
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY 14853, USA
    FASEB J 26:3563-74. 2012

Collaborators

  • Sally P Stabler
  • Patsy M Brannon
  • Saurabh Mehta
  • Jesse F Gregory
  • Elliott J Mufson
  • Peter W Nathanielsz
  • Ralph Green
  • Nicholas D E Greene
  • Wei Wang
  • Sheila M Innis
  • PATRICK STOVER
  • Jian Yan
  • Xinyin Jiang
  • Allyson A West
  • Olga V Malysheva
  • Cydne A Perry
  • Robert H Allen
  • Heyjun Park
  • Ariel B Ganz
  • Anita Ganti
  • Barbara J Strupp
  • Olga Malysheva
  • Eva Pressman
  • Srisatish Devapatla
  • Kelsey Shields
  • Francoise Vermeylen
  • Clara E Cho
  • Vanessa V Cohen
  • Jasmine C Chuang
  • Jessica Lovesky
  • Camille C Swersky
  • Sanjay Mohan
  • Gerardo A Vitiello
  • Bradley Carrier
  • Yusnier S Lopez
  • Siraphat Taesuwan
  • Stephen D Ginsberg
  • Crystal Davenport
  • Sajin Bae
  • Karen E Christensen
  • Melissa J Alldred
  • Jessica A Ash
  • Sara Jones
  • Martha S Field
  • Haim Y Bar
  • Martin T Wells
  • J Yan
  • J Thomas Brenna
  • Jennifer T Fox
  • Julie Stover
  • Jessica L Sutter
  • Vladislav G Fomin
  • Nathan F Tulchinsky
  • Erica Bender
  • Brian E Powers
  • Ramón Velázquez
  • Christy M Kelley
  • Myla Strawderman
  • Vlad G Fomin
  • Siraphat Taeswuan
  • Erika Mudrak
  • Julie A Stover
  • Kit Yi Leung
  • Qing Wu
  • Leonie G Mikael
  • Liyuan Deng
  • Rima Rozen
  • Nancy Lévesque
  • Ana Best
  • Antoinette Gayle
  • Lauren K Lucas
  • Brian Powers
  • Natasa Giallourou
  • Arthur Saltzman
  • Mark S Roberson
  • Benjamin Y Andrew
  • Kelsey S Shields
  • Elena V Abarinov
  • B Burns-Whitmore
  • F Vermeylen
  • Francoise M Vermeylen
  • L B Winter
  • William K Shin

Detail Information

Publications29

  1. pmc Maternal obesity disrupts the methionine cycle in baboon pregnancy
    Peter W Nathanielsz
    Center for Pregnancy and Newborn Research, Department OB GYN, University of Texas Health Science Center San Antonio, San Antonio, Texas Texas Center for Pregnancy and Life Course Health, Southwest National Primate Research Institute Texas Biomedical Research Institute, San Antonio, Texas
    Physiol Rep 3:. 2015
    ....
  2. pmc Plasma choline metabolites associate with metabolic stress among young overweight men in a genotype-specific manner
    J Yan
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Nutr Diabetes 2:e49. 2012
    ....
  3. pmc Choline intake, plasma riboflavin, and the phosphatidylethanolamine N-methyltransferase G5465A genotype predict plasma homocysteine in folate-deplete Mexican-American men with the methylenetetrahydrofolate reductase 677TT genotype
    Marie A Caudill
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY 14853, USA
    J Nutr 139:727-33. 2009
    ..001); an effect confined to the MTHFR 677TT genotype. Thus, in folate-deplete men, several factors with roles in 1-carbon metabolism interact with the MTHFR C677T genotype to affect plasma tHcy...
  4. pmc Folate bioavailability: implications for establishing dietary recommendations and optimizing status
    Marie A Caudill
    Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 91:1455S-1460S. 2010
    ....
  5. doi request reprint Pre- and postnatal health: evidence of increased choline needs
    Marie A Caudill
    Cornell University, Division of Nutritional Sciences, 228 Savage Hall, Ithaca, NY, USA
    J Am Diet Assoc 110:1198-206. 2010
    ..Because choline is not found in most varieties of prenatal vitamins (or regular multivitamins), increased consumption of choline-rich foods may be needed to meet the high pre- and postnatal demands for choline...
  6. doi request reprint Pregnancy alters choline dynamics: results of a randomized trial using stable isotope methodology in pregnant and nonpregnant women
    Jian Yan
    Division of Nutritional Sciences, Cornell University, Ithaca, NY JY, XJ, AAW, OVM, JTB, and MAC the Family and Consumer Sciences Nutrition, Shepherd University, Shepherdstown, WV CAP the Department of Medicine and Division of Hematology, University of Colorado School of Medicine, Aurora, CO SPS and RHA and the Department of Food Science and Human Nutrition, University of Florida, Gainesville, FL JFG
    Am J Clin Nutr 98:1459-67. 2013
    ..Although biomarkers of choline metabolism are altered by pregnancy, little is known about the influence of human pregnancy on the dynamics of choline-related metabolic processes...
  7. doi request reprint A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1)
    Xinyin Jiang
    Division of Nutritional Sciences, Cornell University, 228 Savage Hall, Ithaca, NY 14853, USA
    FASEB J 27:1245-53. 2013
    ..These findings indicate that supplementing the maternal diet with extra choline may improve placental angiogenesis and mitigate some of the pathological antecedents of preeclampsia...
  8. doi request reprint Choline inadequacy impairs trophoblast function and vascularization in cultured human placental trophoblasts
    Xinyin Jiang
    Division of Nutritional Science, Cornell University, Ithaca, New York
    J Cell Physiol 229:1016-27. 2014
    ..Together these results suggest that choline inadequacy may contribute to placental dysfunction and the development of disorders related to placental insufficiency by activating PKC...
  9. pmc Reduced MTHFD1 activity in male mice perturbs folate- and choline-dependent one-carbon metabolism as well as transsulfuration
    Martha S Field
    Division of Nutritional Science, Cornell University, Ithaca, NY, USA
    J Nutr 143:41-5. 2013
    ....
  10. doi request reprint Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans
    Xinyin Jiang
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY 14853, USA
    FASEB J 26:3563-74. 2012
    ..These data collectively suggest that maternal choline intake in humans modulates the epigenetic state of genes that regulate fetal HPA axis reactivity as well as the epigenomic status of fetal derived tissues...
  11. pmc Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women
    Xinyin Jiang
    Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America
    PLoS ONE 7:e46736. 2012
    ..Nevertheless, the interplay between human pregnancy, choline and the human genome is largely unexplored...
  12. ncbi request reprint Folate-status response to a controlled folate intake in nonpregnant, pregnant, and lactating women
    Allyson A West
    Division of Nutritional Science, Cornell University, Ithaca, NY, USA
    Am J Clin Nutr 96:789-800. 2012
    ..Folate dose-response studies in women of childbearing age who consumed a folic acid (FA)-containing multivitamin in the era of FA fortification are lacking...
  13. pmc Vitamin D Metabolism Varies among Women in Different Reproductive States Consuming the Same Intakes of Vitamin D and Related Nutrients
    Heyjun Park
    Division of Nutritional Sciences, Cornell University, Ithaca, NY
    J Nutr 146:1537-45. 2016
    ..The impact of the reproductive state on vitamin D metabolism and requirements is uncertain in part because of a lack of studies with controlled dietary intakes of vitamin D and related nutrients...
  14. doi request reprint Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
    Jian Yan
    Division of Nutritional Science, Cornell University, Ithaca, NY 14583, USA
    Am J Clin Nutr 95:1060-71. 2012
    ..However, to our knowledge, no dose-response studies have been conducted to evaluate the effects of pregnancy or maternal choline intake on biomarkers of choline metabolism...
  15. doi request reprint Choline intakes exceeding recommendations during human lactation improve breast milk choline content by increasing PEMT pathway metabolites
    Crystal Davenport
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    J Nutr Biochem 26:903-11. 2015
    ..This trial was registered at clinicaltrials.gov as NCT01127022...
  16. doi request reprint Vitamin B-12 Status Differs among Pregnant, Lactating, and Control Women with Equivalent Nutrient Intakes
    Sajin Bae
    Division of Nutritional Sciences, Cornell University, Ithaca, NY and
    J Nutr 145:1507-14. 2015
    ..Limited data are available from controlled studies on biomarkers of maternal vitamin B-12 status...
  17. doi request reprint Choline intake influences phosphatidylcholine DHA enrichment in nonpregnant women but not in pregnant women in the third trimester
    Allyson A West
    Division of Nutritional Science, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 97:718-27. 2013
    ..It is unknown whether choline, which can serve as a source of S-adenosylmethionine methyl groups, influences PC-DHA or the PC:PE ratio in pregnant and nonpregnant women...
  18. pmc MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline
    Jian Yan
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY 14853, USA
    Am J Clin Nutr 93:348-55. 2011
    ..The choline adequate intake is 550 mg/d for men, although the metabolic consequences of consuming extra choline are unclear...
  19. pmc Maternal vitamin D biomarkers are associated with maternal and fetal bone turnover among pregnant women consuming controlled amounts of vitamin D, calcium, and phosphorus
    Heyjun Park
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Bone 95:183-191. 2017
    ..Overall, our study findings suggest that achieving higher maternal concentrations of vitamin D biomarkers might attenuate third-trimester bone resorption while ensuring sufficient calcium delivery to the fetus...
  20. pmc Maternal Choline Supplementation: A Potential Prenatal Treatment for Down Syndrome and Alzheimer's Disease
    Barbara J Strupp
    Division of Nutritional Sciences and Department of Psychology, Cornell University, Ithaca, NY, USA
    Curr Alzheimer Res 13:97-106. 2016
    ....
  21. pmc Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet
    Cydne A Perry
    Shepherd University, Shepherdstown, WV and Division of Nutritional Sciences, Cornell University, Ithaca, NY
    J Nutr 144:1977-84. 2014
    ..The biotin AI for adults and pregnant women is 30 μg/d, whereas 35 μg/d is recommended for lactating women. However, pregnant and lactating women may require more biotin to meet the demands of these reproductive states...
  22. doi request reprint Genetic variation: impact on folate (and choline) bioefficacy
    Allyson A West
    Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY, USA
    Int J Vitam Nutr Res 80:319-29. 2010
    ..Nutrient-gene and gene-gene interactions will be considered along with the need to account for these genetic variants when updating dietary folate and choline recommendations...
  23. pmc Genetic Variation in Choline-Metabolizing Enzymes Alters Choline Metabolism in Young Women Consuming Choline Intakes Meeting Current Recommendations
    Ariel B Ganz
    Cornell University, Division of Nutritional Sciences, Ithaca, NY 14853, USA
    Int J Mol Sci 18:. 2017
    ..Such metabolic differences may contribute to disease pathogenesis and prognosis over the long-term...
  24. doi request reprint Trimethylamine-N-oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial
    Clara E Cho
    Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA
    Mol Nutr Food Res 61:. 2017
    ..We hypothesized that (i) TMAO response to animal source foods would vary among healthy men and (ii) this response would be modified by their gut microbiome...
  25. pmc Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis
    Ariel B Ganz
    Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA and
    FASEB J 30:3321-3333. 2016
    ..C., Stover, J. A., Vitiello, G. A., Malysheva, O. V., Mudrak, E., Caudill, M. A. Genetic impairments in folate enzymes increase dependence on dietary choline for phosphatidylcholine production at the expense of betaine synthesis...
  26. pmc Maternal choline supplementation programs greater activity of the phosphatidylethanolamine N-methyltransferase (PEMT) pathway in adult Ts65Dn trisomic mice
    Jian Yan
    Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA
    FASEB J 28:4312-23. 2014
    ..These data demonstrate that MCS exerts lasting effects on offspring choline metabolism, including up-regulation of the hepatic PEMT pathway and enhanced provision of choline and PEMT-PC to the brain...
  27. pmc High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice
    Karen E Christensen
    From the Departments of Human Genetics and Pediatrics, McGill University, and the Montreal Children s Hospital site of the McGill University Health Centre Research Institute, Montreal, Quebec, Canada KEC, LGM, NL, LD, QW, and RR Developmental Biology and Cancer Programme, Institute of Child Health, University College London, London, United Kingdom K YL and NDEG the Division of Nutritional Sciences and Genomics, Cornell University, Ithaca, NY OVM and MAC and the Department of Mathematics and Statistics, McGill University, Montreal, Quebec, Canada AB
    Am J Clin Nutr 101:646-58. 2015
    ..The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown. Methylenetetrahydrofolate reductase (MTHFR) provides methyl donors for S-adenosylmethionine (SAM) synthesis and methylation reactions...
  28. doi request reprint Genetic and epigenetic contributions to human nutrition and health: managing genome-diet interactions
    Patrick J Stover
    Cornell University, Division of Nutritional Sciences, Ithaca, NY 14853, USA
    J Am Diet Assoc 108:1480-7. 2008
    ....
  29. pmc A UV-responsive internal ribosome entry site enhances serine hydroxymethyltransferase 1 expression for DNA damage repair
    Jennifer T Fox
    Graduate Field of Biochemistry and Molecular and Cellular Biology, Cornell University, Ithaca, New York 14853, USA
    J Biol Chem 284:31097-108. 2009
    ....