- Inner ear drug delivery for auditory applicationsErin E Leary Swan
Charles Stark Draper Laboratory, 555 Technology Square, Cambridge, MA 02139, USA
Adv Drug Deliv Rev 60:1583-99. 2008..Innovative drug delivery systems to treat various inner ear ailments such as ototoxicity, sudden sensorineural hearing loss, autoimmune inner ear disease, and for preserving neurons and regenerating sensory cells are being explored...
- Fabrication Methods and Performance of Low-Permeability Microfluidic Components for a Miniaturized Wearable Drug Delivery SystemMark J Mescher
Charles Stark Draper Laboratory, Cambridge, MA 02139 USA
J Microelectromech Syst 18:501-510. 2009..015 to 0.15 μL/kPa, screw valves with on/off flow ratios greater than 38 000, and a 45× reduction in the aqueous fluid loss rate to the ambient due to permeation through a silicone diaphragm layer...
- Proteomics analysis of perilymph and cerebrospinal fluid in mouseErin E Leary Swan
Charles Stark Draper Laboratory, Cambridge, Massachusetts, USA
Laryngoscope 119:953-8. 2009..Proteins in perilymph may alter the delivery profile of implantable intracochlear drug delivery systems through biofouling. Knowledge of protein composition will help anticipate interactions with delivered agents...