Andrew F Teich

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. ncbi request reprint Comparison among some models of orientation selectivity
    Andrew F Teich
    Center for Neurobiology and Behavior, Mahoney Center for Brain and Behaviour Research, and Department of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA
    J Neurophysiol 96:404-19. 2006
  2. pmc A reliable way to detect endogenous murine β-amyloid
    Andrew F Teich
    Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, New York, United States of America
    PLoS ONE 8:e55647. 2013
  3. pmc Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant?
    Andrew F Teich
    Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, PH15 124, New York, NY 10032, USA
    Biochem J 446:165-77. 2012
  4. pmc V1 orientation plasticity is explained by broadly tuned feedforward inputs and intracortical sharpening
    Andrew F Teich
    Department of Pathology, Columbia University, New York, New York 10032, USA
    Vis Neurosci 27:57-73. 2010
  5. pmc PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease
    Andrew F Teich
    Department of Pathology and Cell Biology, Columbia University, New York, NY, USA
    J Alzheimers Dis 52:295-302. 2016
  6. doi request reprint Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease
    Mauro Fa
    Department of Pathology and Cell Biology, The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
    J Alzheimers Dis 49:707-21. 2016
  7. ncbi request reprint Learning and adaptation in a recurrent model of V1 orientation selectivity
    Andrew F Teich
    Center for Neurobiology and Behavior and Department of Physiology and Cellular Biophysics, Columbia University, New York, New York 10032, USA
    J Neurophysiol 89:2086-100. 2003
  8. pmc Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer's disease
    Peter Koppensteiner
    Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA
    Sci Rep 6:32553. 2016
  9. pmc Synaptic therapy in Alzheimer's disease: a CREB-centric approach
    Andrew F Teich
    Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, 10032, USA
    Neurotherapeutics 12:29-41. 2015
  10. doi request reprint 5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulation
    Gakuji Hashimoto
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
    J Alzheimers Dis 32:437-45. 2012

Research Grants

Collaborators

  • Ottavio Arancio
  • Daniela Puzzo
  • Hong Zhang
  • Ipe Ninan
  • Mauro Fa
  • Peter Koppensteiner
  • Faisal Saeed
  • Gakuji Hashimoto
  • Arthur Poussin
  • VLADISLAV A LITOSH
  • Pavel A Petukhov
  • Li W Shen
  • Elena Dale
  • Shumin Liu
  • Fabrizio Trinchese
  • Shijun Yan
  • Stefan Boehm
  • Agnieszka Staniszewski
  • Subhasish Tapadar
  • Jenny Libien
  • Walter Gulisano
  • Gregory R J Thatcher
  • IAN OROZCO
  • Isaac T Schiefer
  • Marton I Siklos
  • Agostino Palmeri
  • Fahad Aziz
  • Mikako Sakurai

Detail Information

Publications10

  1. ncbi request reprint Comparison among some models of orientation selectivity
    Andrew F Teich
    Center for Neurobiology and Behavior, Mahoney Center for Brain and Behaviour Research, and Department of Physiology and Cellular Biophysics, Columbia University, New York, NY 10032, USA
    J Neurophysiol 96:404-19. 2006
    ..Because orientation-tuned V1 cells show a continuum of simple- to complex-cell behavior, the MRM provides the best description of V1 data...
  2. pmc A reliable way to detect endogenous murine β-amyloid
    Andrew F Teich
    Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, New York, United States of America
    PLoS ONE 8:e55647. 2013
    ..Here, we examine the background signal of several murine β-amyloid ELISAs, and conclude that the majority of the background is from non-APP derived proteins. Most importantly, we identify ELISAs that eliminate this background signal...
  3. pmc Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant?
    Andrew F Teich
    Department of Pathology and Cell Biology, Columbia University Medical Center, 630 West 168th Street, PH15 124, New York, NY 10032, USA
    Biochem J 446:165-77. 2012
    ....
  4. pmc V1 orientation plasticity is explained by broadly tuned feedforward inputs and intracortical sharpening
    Andrew F Teich
    Department of Pathology, Columbia University, New York, New York 10032, USA
    Vis Neurosci 27:57-73. 2010
    ..We predict that the plastic properties must be absent for cells whose orientation tuning arises from a feedforward mechanism...
  5. pmc PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease
    Andrew F Teich
    Department of Pathology and Cell Biology, Columbia University, New York, NY, USA
    J Alzheimers Dis 52:295-302. 2016
    ..Most importantly, we performed immunohistochemistry and demonstrate that PDE5 is present in human neurons. We hope that this work will trigger a renewed interest in the development of PDE5 inhibitors for neurologic disease...
  6. doi request reprint Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease
    Mauro Fa
    Department of Pathology and Cell Biology, The Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, USA
    J Alzheimers Dis 49:707-21. 2016
    ..Both functional and preliminary toxicological investigations proved the efficacy, potency, and safety of the novel and selective calpain inhibitors NYC438 and NYC488 as possible therapeutics against the disease. ..
  7. ncbi request reprint Learning and adaptation in a recurrent model of V1 orientation selectivity
    Andrew F Teich
    Center for Neurobiology and Behavior and Department of Physiology and Cellular Biophysics, Columbia University, New York, New York 10032, USA
    J Neurophysiol 89:2086-100. 2003
    ..Instead, human adaptation studies can be better accounted for by the learning data from behaving animals. Our work suggests that adaptation in behaving subjects may be viewed as a short-term form of learning...
  8. pmc Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer's disease
    Peter Koppensteiner
    Department of Pathology and Cell Biology, Columbia University, New York, NY, 10032, USA
    Sci Rep 6:32553. 2016
    ....
  9. pmc Synaptic therapy in Alzheimer's disease: a CREB-centric approach
    Andrew F Teich
    Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University, New York, NY, 10032, USA
    Neurotherapeutics 12:29-41. 2015
    ....
  10. doi request reprint 5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulation
    Gakuji Hashimoto
    Taub Institute for Research on Alzheimer s Disease and the Aging Brain, Columbia University Medical Center, New York, NY, USA
    J Alzheimers Dis 32:437-45. 2012
    ..Taken all together, these experiments demonstrate that 5-HT4 receptor stimulation induces expression of MMP-9 which cleaves AβPP through α-secretase-like activity, leading to an increase of sAβPPα levels and a reduction of Aβ load...

Research Grants1

  1. Learning and Adaptation in Primary Visual Cortex
    ANDREW TEICH; Fiscal Year: 2005
    ..The goal of Specific Aim 2 is to experimentally test the prediction that adaptation in alert, non-anesthetized subjects causes physiological changes that are a transient version of the changes seen in learning. ..