Xinhua Liu

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc Folate, Cobalamin, Cysteine, Homocysteine, and Arsenic Metabolism among Children in Bangladesh
    Megan N Hall
    Department of Epidemiology, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 117:825-31. 2009
  2. pmc Comparing paired biomarkers in predicting quantitative health outcome subject to random censoring
    Xinhua Liu
    Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA
    Stat Methods Med Res 25:447-57. 2016
  3. pmc A cluster-based randomized controlled trial promoting community participation in arsenic mitigation efforts in Bangladesh
    Christine Marie George
    Department of International Health, Program in Global Disease Epidemiology and Control, Johns Hopkins Bloomberg School of Public, 615 N, Wolfe Street, Room E5535, Baltimore, Maryland 21205 2103, USA
    Environ Health 11:41. 2012
  4. doi request reprint Classification accuracy and cut point selection
    Xinhua Liu
    Department of Biostatistics, Columbia University, New York, NY 10032, USA
    Stat Med 31:2676-86. 2012
  5. ncbi request reprint Item reduction in a scale for screening
    Xinhua Liu
    Department of Biostatistics, Columbia University, New York, NY 10032, USA
    Stat Med 26:4311-27. 2007
  6. pmc Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 115:285-9. 2007
  7. pmc Arsenic and manganese exposure and children's intellectual function
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York City, NY 10032, USA
    Neurotoxicology 32:450-7. 2011
  8. ncbi request reprint Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults
    J Richard Pilsner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, B1, New York, NY 10032, USA
    Am J Clin Nutr 86:1179-86. 2007
  9. pmc Folic acid supplementation lowers blood arsenic
    Mary V Gamble
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 86:1202-9. 2007
  10. pmc Influence of cobalamin on arsenic metabolism in Bangladesh
    Megan N Hall
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 117:1724-9. 2009

Detail Information

Publications106 found, 100 shown here

  1. pmc Folate, Cobalamin, Cysteine, Homocysteine, and Arsenic Metabolism among Children in Bangladesh
    Megan N Hall
    Department of Epidemiology, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 117:825-31. 2009
    ..Methylation of InAs to monomethylarsonic (MMA) and dimethylarsinic acids (DMA) relies on folate-dependent one-carbon metabolism and facilitates urinary arsenic (uAs) elimination...
  2. pmc Comparing paired biomarkers in predicting quantitative health outcome subject to random censoring
    Xinhua Liu
    Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA
    Stat Methods Med Res 25:447-57. 2016
    ..The second study on 418 patients with primary biliary cirrhosis found that the baseline serum bilirubin had greater discrimination accuracy than the baseline serum albumin in predicting survival time. ..
  3. pmc A cluster-based randomized controlled trial promoting community participation in arsenic mitigation efforts in Bangladesh
    Christine Marie George
    Department of International Health, Program in Global Disease Epidemiology and Control, Johns Hopkins Bloomberg School of Public, 615 N, Wolfe Street, Room E5535, Baltimore, Maryland 21205 2103, USA
    Environ Health 11:41. 2012
    ....
  4. doi request reprint Classification accuracy and cut point selection
    Xinhua Liu
    Department of Biostatistics, Columbia University, New York, NY 10032, USA
    Stat Med 31:2676-86. 2012
    ..Using data from a real-world study of arsenic-induced skin lesions, we apply the method to a measure of blood arsenic levels, selecting a cut point to be used as a warning threshold...
  5. ncbi request reprint Item reduction in a scale for screening
    Xinhua Liu
    Department of Biostatistics, Columbia University, New York, NY 10032, USA
    Stat Med 26:4311-27. 2007
    ..The method is illustrated with a data set on patients with and without high risk of developing Alzheimer's disease who were administered a 40-item test of olfactory function...
  6. pmc Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 115:285-9. 2007
    ..We recently reported results of a cross-sectional investigation of intellectual function in 10-year-olds in Bangladesh, who had been exposed to arsenic from drinking water in their home wells...
  7. pmc Arsenic and manganese exposure and children's intellectual function
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York City, NY 10032, USA
    Neurotoxicology 32:450-7. 2011
    ..25). Findings are consistent with other reports documenting adverse impact of both As and Mn exposure on child developmental outcomes, although associations appear muted at these relatively low exposure levels...
  8. ncbi request reprint Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults
    J Richard Pilsner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, B1, New York, NY 10032, USA
    Am J Clin Nutr 86:1179-86. 2007
    ..It is not known whether arsenic exposure influences genomic DNA methylation in human populations chronically exposed to arsenic-contaminated drinking water...
  9. pmc Folic acid supplementation lowers blood arsenic
    Mary V Gamble
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 86:1202-9. 2007
    ..Methylation of ingested inorganic arsenic (InAs) to monomethylarsonic (MMAs) and dimethylarsinic (DMAs) acids relies on folate-dependent one-carbon metabolism and facilitates urinary arsenic elimination...
  10. pmc Influence of cobalamin on arsenic metabolism in Bangladesh
    Megan N Hall
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 117:1724-9. 2009
    ..Although DMA(V) is the least toxic metabolite, increasing evidence suggests that MMA(III) may be the most cytotoxic and genotoxic As intermediary metabolite...
  11. pmc Water manganese exposure and children's intellectual function in Araihazar, Bangladesh
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, and New York State Psychiatric Institute, New York, New York 10032, USA
    Environ Health Perspect 114:124-9. 2006
    ..S. Environmental Protection Agency lifetime health advisory level. We conclude that in both Bangladesh and the United States, some children are at risk for Mn-induced neurotoxicity...
  12. pmc Determinants of arsenic metabolism: blood arsenic metabolites, plasma folate, cobalamin, and homocysteine concentrations in maternal-newborn pairs
    Marni Hall
    Department of Environmental Health Sciences, Columbia University Medical Center, New York, New York 10032, USA
    Environ Health Perspect 115:1503-9. 2007
    ..In Bangladesh, tens of millions of people have been consuming waterborne arsenic for decades. The extent to which As is transported to the fetus during pregnancy has not been well characterized...
  13. pmc Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh
    Mary V Gamble
    Departments of Environmental Health Sciences, Columbia University, New York, NY, USA
    Am J Clin Nutr 84:1093-101. 2006
    ..Consequently, folate nutritional status may influence arsenic methylation and toxicity...
  14. pmc Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh
    Mary V Gamble
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Environ Health Perspect 113:1683-8. 2005
    ..This may be particularly relevant in Bangladesh, where the prevalence of hyperhomocysteinemia is extremely high...
  15. pmc Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions
    J Richard Pilsner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Ave, B1, New York, NY 10032 USA
    Environ Health Perspect 117:254-60. 2009
    ..Clinical manifestations of As toxicity vary considerably among individuals and populations, and poor methylation capacity is thought to confer greater susceptibility...
  16. pmc A dose-response study of arsenic exposure and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults
    Megan M Niedzwiecki
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Health Perspect 121:1306-12. 2013
    ..However, As has been associated with global DNA hypermethylation in human study populations. We hypothesized that this discrepancy may reflect a nonlinear relationship between As dose and DNA methylation...
  17. pmc Associations of plasma selenium with arsenic and genomic methylation of leukocyte DNA in Bangladesh
    J Richard Pilsner
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 119:113-8. 2011
    ..In addition, antagonism between As and Se, whereby each reduces toxicity of the other, has been well documented in animal models. Se status may therefore modify the health effects of As in As-exposed populations...
  18. pmc Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease
    Davangere P Devanand
    Division of Geriatric Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Biol Psychiatry 64:871-9. 2008
    ..The utility of combining early markers to predict conversion from mild cognitive impairment (MCI) to Alzheimer's Disease (AD) remains uncertain...
  19. pmc The relationship between depressive symptom levels and subsequent increases in substance use among youth with severe emotional disturbance
    Ping Wu
    Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    J Stud Alcohol Drugs 69:520-7. 2008
    ..This study examined the relationship between levels of depressive symptoms and subsequent increases in substance use among 784 youth with severe emotional disturbance enrolled in Medicaid-funded behavioral health care plans...
  20. pmc The psychological impact of the SARS epidemic on hospital employees in China: exposure, risk perception, and altruistic acceptance of risk
    Ping Wu
    Departments of Psychiatry and Epidemiology, Columbia University, New York, New York 10032, USA
    Can J Psychiatry 54:302-11. 2009
    ..We examined the psychological impact of the 2003 outbreak of severe acute respiratory syndrome (SARS) on hospital employees in Beijing, China...
  21. ncbi request reprint Neuropsychological prediction of conversion to Alzheimer disease in patients with mild cognitive impairment
    Matthias H Tabert
    Department of Psychiatry, Columbia University College of Physicians and Surgeons and the New York State Psychiatric Institute, 1051 Riverside Dr, Unit 126, New York, NY 10032, USA
    Arch Gen Psychiatry 63:916-24. 2006
    ..The likelihood of conversion to Alzheimer disease (AD) in mild cognitive impairment (MCI) and the "optimal" early markers of conversion need to be established...
  22. pmc Arsenic exposure and motor function among children in Bangladesh
    Faruque Parvez
    Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA
    Environ Health Perspect 119:1665-70. 2011
    ..Very little is known, however, about possible associations with other neurologic outcomes such as motor function...
  23. pmc Urinary naphthol metabolites and chromosomal aberrations in 5-year-old children
    Manuela A Orjuela
    Department of Pediatrics, Columbia University, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 21:1191-202. 2012
    ..Although prenatal (maternal) PAH exposure predicts chromosomal aberrations in cord blood, few studies have examined chromosomal aberrations in school-age children and none has examined their association with metabolites of specific PAHs...
  24. ncbi request reprint Independent versus substance-induced major depressive disorder in substance-dependent patients: observational study of course during follow-up
    Edward V Nunes
    Department of Psychiatry, College of Physicians and Surgeons, New York State Psychiatric Institute, NY, USA
    J Clin Psychiatry 67:1561-7. 2006
    ..The authors examined whether baseline and past diagnoses of DSM-IV primary (independent) or substance-induced depression or other psychiatric syndromes predict 1-year course of depression in substance-dependent patients...
  25. pmc The relationship between anxiety disorders and substance use among adolescents in the community: specificity and gender differences
    Ping Wu
    Mailman School of Public Health, Columbia University, New York, NY, USA
    J Youth Adolesc 39:177-88. 2010
    ..Future studies based on longitudinal data could further elucidate the relationships among anxiety disorders, gender, and substance use...
  26. pmc Trauma, posttraumatic stress symptoms, and alcohol-use initiation in children
    Ping Wu
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, Unit 43, New York, New York 10032, USA
    J Stud Alcohol Drugs 71:326-34. 2010
    ..This study examined initiation of alcohol use among adolescents, in relation to their earlier traumatic experiences and symptoms of posttraumatic stress disorder (PTSD)...
  27. pmc Depression after exposure to stressful events: lessons learned from the severe acute respiratory syndrome epidemic
    Xinhua Liu
    Mailman School of Public Health, Columbia University, NY10032, USA
    Compr Psychiatry 53:15-23. 2012
    ....
  28. ncbi request reprint Need for mental health services and service use among high school students in China
    Ping Wu
    Department of Psychiatry, Columbia University, 1051 Riverside Dr, Unit 43, New York, NY 10032, USA
    Psychiatr Serv 63:1026-31. 2012
    ..This study examined rates of mental health service use and associated factors among Chinese adolescents...
  29. pmc Chronic arsenic exposure and blood glutathione and glutathione disulfide concentrations in Bangladeshi adults
    Megan N Hall
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Health Perspect 121:1068-74. 2013
    ....
  30. pmc Blood glutathione redox status and global methylation of peripheral blood mononuclear cell DNA in Bangladeshi adults
    Megan M Niedzwiecki
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    Epigenetics 8:730-8. 2013
    ..Furthermore, blood SAM does not appear to mediate this association. Future research should explore mechanisms through which cellular redox might influence global DNA methylation. ..
  31. pmc Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats
    Sarah M Mense
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, New York, NY 10032, USA
    Carcinogenesis 30:1202-8. 2009
    ..Taken together, these results suggest that E(2) metabolism and oxidant stress are critically involved in estrogen-induced breast carcinogenesis...
  32. pmc Adolescent substance use and other illegal behaviors and racial disparities in criminal justice system involvement: findings from a US national survey
    Meghana Kakade
    Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, USA
    Am J Public Health 102:1307-10. 2012
    ..Racial disparities in adolescent arrest appear to result from differential treatment of minority youths and to have long-term negative effects on the lives of affected African American youths...
  33. pmc Fluorescence in situ hybridization is necessary to detect an association between chromosome aberrations and polycyclic aromatic hydrocarbon exposure in utero and reveals nonrandom chromosome involvement
    Kirsti A Bocskay
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Mol Mutagen 48:114-23. 2007
    ..Together, these results suggest that PAHs may be targeting specific chromosomes and highlight the importance of using the more sensitive detection methods to assess risk in populations with low levels of exposure...
  34. ncbi request reprint Environmental lead exposure, maternal thyroid function, and childhood growth
    Matthew R Lamb
    Department of Epidemiology, Mailman School of Public Health, Columbia University, USA
    Environ Res 106:195-202. 2008
    ..5 to 10 years, in the low-exposure town. We examine potential reasons for this unexpected inverse association...
  35. pmc Pittsburgh compound B (11C-PIB) and fluorodeoxyglucose (18 F-FDG) PET in patients with Alzheimer disease, mild cognitive impairment, and healthy controls
    D P Devanand
    Division of Geriatric Psychiatry, Columbia University, New York, USA
    J Geriatr Psychiatry Neurol 23:185-98. 2010
    ..These PET techniques provide complementary information in strongly distinguishing diagnostic groups in cross-sectional comparisons that need testing in longitudinal studies...
  36. pmc Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age
    Robin M Whyatt
    Department of Environmental Health Sciences, Columbia Center for Children s Environmental Health Department of Environmental Health Sciences, Mailman School of Public Health, 722 West 168th St, New York, NY 10032 USA
    Environ Health Perspect 120:290-5. 2012
    ..Research suggests that prenatal phthalate exposures affect child executive function and behavior...
  37. pmc Prenatal PAH exposure is associated with chromosome-specific aberrations in cord blood
    Manuela A Orjuela
    Departments of Pediatrics Oncology, Environmental Health Sciences, Biostatistics and Genetics, Columbia University, New York, NY, United States
    Mutat Res 703:108-14. 2010
    ..The observed chromosome-specific effects of prenatal airborne PAHs raise concern about potential cancer risk...
  38. pmc No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in Bangladesh
    Yu Chen
    Department of Environmental Medicine, New York University School of Medicine, New York, New York, USA
    Environ Health Perspect 118:1299-305. 2010
    ..The long-term effects of arsenic exposure from drinking water at levels < 300 microg/L and the risk of diabetes mellitus remains a controversial topic...
  39. pmc Ecstasy use and suicidal behavior among adolescents: findings from a national survey
    Jueun Kim
    College of Physicians and Surgeons, Columbia University, New York, NY, USA
    Suicide Life Threat Behav 41:435-44. 2011
    ..In multinomial logistic regression analyses controlling for related factors, the effect of ecstasy use remained significant. Adolescent ecstasy users may require enhanced suicide prevention and intervention efforts...
  40. pmc Prenatal polychlorinated biphenyl exposure is associated with decreased gestational length but not birth weight: archived samples from the Child Health and Development Studies pregnancy cohort
    Katrina L Kezios
    Department of Epidemiology, Mailman School of Public Health, Columbia University, Room 1614, 722 West 168th St, New York, NY 10032, USA
    Environ Health 11:49. 2012
    ..Previous studies are inconsistent regarding prenatal exposure to PCBs and pregnancy outcomes. We investigated associations between prenatal exposure to PCBs and gestational length and birth weight...
  41. pmc Arsenic exposure, inflammation, and renal function in Bangladeshi adults: effect modification by plasma glutathione redox potential
    Brandilyn A Peters
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Free Radic Biol Med 85:174-82. 2015
    ..Future studies should evaluate whether antioxidant treatment lowers plasma EhGSH and reduces risk for As-induced diseases...
  42. pmc Evaluation of an Elementary School-based Educational Intervention for Reducing Arsenic Exposure in Bangladesh
    Khalid Khan
    Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA
    Environ Health Perspect 123:1331-6. 2015
    ..Many mitigation programs have been implemented to reduce As exposure, although evaluation studies for these efforts are rare in the literature...
  43. pmc Renal function is associated with indicators of arsenic methylation capacity in Bangladeshi adults
    Brandilyn A Peters
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA
    Environ Res 143:123-30. 2015
    ..The relationship between renal function and indicators of As methylation capacity has not been thoroughly investigated...
  44. pmc Interaction of plasma glutathione redox and folate deficiency on arsenic methylation capacity in Bangladeshi adults
    Megan M Niedzwiecki
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    Free Radic Biol Med 73:67-74. 2014
    ..Our findings suggest that GSH/GSSG redox regulation might contribute to the large interindividual variation in As methylation capacity observed in human populations...
  45. pmc Dichlorodiphenyltrichloroethane (DDT), DDT metabolites and pregnancy outcomes
    Katrina L Kezios
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Reprod Toxicol 35:156-64. 2013
    ..These findings suggest opposing associations between exposure to p,p'-DDT and p,p'-DDE and birth weight. We did not find evidence to support mediation by maternal thyroid hormone status nor that the association differed by sex...
  46. pmc Manganese exposure from drinking water and children's classroom behavior in Bangladesh
    Khalid Khan
    Department of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA
    Environ Health Perspect 119:1501-6. 2011
    ..Little is known about potential effects at lower exposures, especially in children. Moreover, little is known regarding potential interactions between exposure to Mn and other metals, especially arsenic (As)...
  47. pmc (99m)Tc hexamethyl-propylene-aminoxime single-photon emission computed tomography prediction of conversion from mild cognitive impairment to Alzheimer disease
    D P Devanand
    NYSPI, Columbia University, New York, NY 10032, USA
    Am J Geriatr Psychiatry 18:959-72. 2010
    ..To examine the utility of single-photon emission computed tomography (SPECT) to predict conversion from mild cognitive impairment (MCI) to Alzheimer disease (AD)...
  48. pmc Associations between Blood and Urine Arsenic Concentrations and Global Levels of Post-Translational Histone Modifications in Bangladeshi Men and Women
    Caitlin G Howe
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Health Perspect 124:1234-40. 2016
    ..Although evidence from in vitro studies suggests that arsenic alters post-translational histone modifications (PTHMs), evidence in humans is limited...
  49. pmc Child Intelligence and Reductions in Water Arsenic and Manganese: A Two-Year Follow-up Study in Bangladesh
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Environ Health Perspect 124:1114-20. 2016
    ..Arsenic (As) exposure from drinking water is associated with modest intellectual deficits in childhood. It is not known whether reducing exposure is associated with improved intelligence...
  50. pmc Associations between arsenic exposure and global posttranslational histone modifications among adults in Bangladesh
    Yana Chervona
    Department of Environmental Medicine, New York University School of Medicine, Tuxedo, New York, USA
    Cancer Epidemiol Biomarkers Prev 21:2252-60. 2012
    ..Arsenic compounds are weakly mutagenic, alter gene expression and posttranslational histone modifications (PTHMs) in vitro...
  51. pmc Sex-specific associations of arsenic exposure with global DNA methylation and hydroxymethylation in leukocytes: results from two studies in Bangladesh
    Megan M Niedzwiecki
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York
    Cancer Epidemiol Biomarkers Prev 24:1748-57. 2015
    ..Although arsenic (As)-a class I human carcinogen linked to skin lesion and cancer risk-is known to be associated with changes in global %5-methylcytosine (%5-mC), its influence on 5-hmC has not been widely studied...
  52. pmc Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh
    Mary V Gamble
    Department of Environmental Health Sciences, School of Public Health, Columbia University, New York, NY 10032, USA
    Am J Clin Nutr 81:1372-7. 2005
    ..This has been largely attributed to dietary deficiencies in cobalamin associated with vegetarianism among these Indian Asians...
  53. ncbi request reprint A 10-item smell identification scale related to risk for Alzheimer's disease
    Matthias H Tabert
    Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY, USA
    Ann Neurol 58:155-60. 2005
    ..Independent replication is needed to validate these findings...
  54. pmc Exposure to the World Trade Center attack and the use of cigarettes and alcohol among New York City public high-school students
    Ping Wu
    Department of Psychiatry, Columbia University NYSPI, 1051 Riverside Drive, Unit 43, New York, NY 10032, USA
    Am J Public Health 96:804-7. 2006
    ..06). Our findings suggest that targeted substance-use interventions for youths may be warranted after large-scale disasters...
  55. doi request reprint Developmental impacts of heavy metals and undernutrition
    Gail A Wasserman
    Division of Child and Adolescent Psychiatry, Columbia University, New York, NY, USA
    Basic Clin Pharmacol Toxicol 102:212-7. 2008
    ..Stunting affects more than 25% of young children in developing countries. The combined neurocognitive loss from both risks, although rarely jointly studied, represents a substantial loss of global potential...
  56. pmc Factors associated with initiation of ecstasy use among US adolescents: findings from a national survey
    Ping Wu
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, NY 10032, USA
    Drug Alcohol Depend 106:193-8. 2010
    ....
  57. pmc Ecstasy use among US adolescents from 1999 to 2008
    Ping Wu
    Department of Psychiatry, College of Physicians and Surgeons, Unit 43, Columbia University, New York, NY 10032, USA
    Drug Alcohol Depend 112:33-8. 2010
    ..To investigate trends in rates of ecstasy use among US adolescents from 1999 to 2008, and to examine the associations between the major sociodemographic factors, especially gender, and ecstasy use, during this period...
  58. pmc Risk of retinoblastoma is associated with a maternal polymorphism in dihydrofolatereductase (DHFR) and prenatal folic acid intake
    Manuela A Orjuela
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Cancer 118:5912-9. 2012
    ..Maternal intake of naturally occurring folate from vegetables during pregnancy is associated inversely with the risk of retinoblastoma in offspring...
  59. pmc A cross-sectional study of well water arsenic and child IQ in Maine schoolchildren
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University New York, NY, USA
    Environ Health 13:23. 2014
    ..g., Perceptual Reasoning, Working Memory) after adjustment for social factors. Because findings are not easily generalizable to the US, we examine this relation in a US population...
  60. pmc Folic Acid and Creatine as Therapeutic Approaches to Lower Blood Arsenic: A Randomized Controlled Trial
    Brandilyn A Peters
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA
    Environ Health Perspect 123:1294-301. 2015
    ..Although the reasons for this are unclear, creatine synthesis is a major consumer of methyl donors, and this synthesis is down-regulated by dietary/supplemental creatine...
  61. pmc Creatinine, arsenic metabolism, and renal function in an arsenic-exposed population in Bangladesh
    Brandilyn A Peters
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, United States of America
    PLoS ONE 9:e113760. 2014
    ..Discrepancies between the samples may be due to the higher As exposure, poorer nutrition, and lower As methylation capacity in the 2003 sample. ..
  62. pmc A dose-response study of arsenic exposure and markers of oxidative damage in Bangladesh
    Kristin N Harper
    From the Departments of Environmental Health Sciences Dr Harper, Ms Ilievski, Ms Oka, Ms Calancie, Ms Slavkovich, Dr Graziano, and Dr Gamble, Biostatistics Dr Liu and Ms Levy, and Epidemiology Dr Hall, Mailman School of Public Health, Columbia University, New York, NY Columbia University Arsenic Project in Bangladesh Mr Siddique and Mr Alam, Dhaka, Bangladesh Lamont Doherty Earth Observatory Dr Mey and Dr van Geen, Columbia University, Palisades, NY and Kingsbridge Community College Dr Mey, New York, NY
    J Occup Environ Med 56:652-8. 2014
    ..To evaluate the dose-response relationship between arsenic (As) exposure and markers of oxidative damage in Bangladeshi adults...
  63. pmc Functional impairment in elderly patients with mild cognitive impairment and mild Alzheimer disease
    Patrick J Brown
    Division of Geriatric Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
    Arch Gen Psychiatry 68:617-26. 2011
    ....
  64. pmc Speed of processing and depression affect function in older adults with mild cognitive impairment
    Patrick J Brown
    Columbia University College of Physicians and Surgeons and New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Geriatr Psychiatry 21:675-84. 2013
    ..To evaluate the effect of depression and cognition on function in older adults with amnestic and nonamnestic mild cognitive impairment (aMCI and nonaMCI)...
  65. pmc Alcohol abuse/dependence symptoms among hospital employees exposed to a SARS outbreak
    Ping Wu
    Mailman School of Public Health, New York State Psychiatric Institute, Columbia University, 1051 Riverside Drive, Unit 43, NY 10032, USA
    Alcohol Alcohol 43:706-12. 2008
    ....
  66. pmc Prenatal exposure to pesticide ingredient piperonyl butoxide and childhood cough in an urban cohort
    Bian Liu
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168 Street, PH8E 101, New York, NY 10032, USA
    Environ Int 48:156-61. 2012
    ..Further, we explored the associations between these pesticide measures and wheeze, asthma, seroatopy, and fractional exhaled nitric oxide (FeNO)...
  67. doi request reprint CD20 expression predicts survival in paediatric post-transplant lymphoproliferative disease (PTLD) following solid organ transplantation
    Manuela A Orjuela
    Departments of Pediatrics, Columbia University, New York Presbyterian Morgan Stanley Children s Hospital New York, NY, USA
    Br J Haematol 152:733-42. 2011
    ..56·3%, P = 0·01). EBV expression was unrelated to PTLD-related EFS or OS. CD20 expression is associated with timing of development of PTLD and predicts survival in PTLD diagnosed following paediatric SOT...
  68. pmc Predictors of serum concentrations of polybrominated flame retardants among healthy pregnant women in an urban environment: a cross-sectional study
    Megan K Horton
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA
    Environ Health 12:23. 2013
    ..Our objective was to characterize predictors of exposure to PBDEs among a multi-ethnic, low-income cohort of pregnant women enrolled from highly urban communities in New York City between years 2009-2010...
  69. pmc Repeatedly high polycyclic aromatic hydrocarbon exposure and cockroach sensitization among inner-city children
    Kyung Hwa Jung
    Division of Pulmonary, Allergy and Critical Care of Medicine, Department of Medicine, College of Physicians and Surgeons, Columbia University, PH8E 101, 630 W 168 Street, New York, NY 10032, United States Electronic address
    Environ Res 140:649-56. 2015
    ..We hypothesized that repeatedly high PAH exposure during childhood would be associated with increased risk of new cockroach sensitization...
  70. pmc A two-study comparison of clinical and MRI markers of transition from mild cognitive impairment to Alzheimer's disease
    D P Devanand
    Division of Geriatric Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, Unit 126, New York, NY 10032, USA
    Int J Alzheimers Dis 2012:483469. 2012
    ..The predictor models showed similar differences from each other in both studies, supporting independent validation. MRI hippocampal and entorhinal cortex volumes showed limited added predictive utility to memory and function measures...
  71. ncbi request reprint Effects of major depression on remission and relapse of substance dependence
    Deborah Hasin
    Mailman School of Public Health, Division of Epidemiology, College of Physicians and Surgeons, Columbia University and New York State Psychiatric Institute, 1051 Riverside Dr, Box 123, New York, NY 10032, USA
    Arch Gen Psychiatry 59:375-80. 2002
    ....
  72. ncbi request reprint Alcohol and ADH2 in Israel: Ashkenazis, Sephardics, and recent Russian immigrants
    Deborah Hasin
    Division of Epidemiology, Mailman School of Public Health, Columbia University, New York 10032, USA
    Am J Psychiatry 159:1432-4. 2002
    ....
  73. ncbi request reprint Suicide attempts in substance abusers: effects of major depression in relation to substance use disorders
    Efrat Aharonovich
    College of Physicians and Surgeons, Department of Psychiatry, Columbia University, USA
    Am J Psychiatry 159:1600-2. 2002
    ..The authors' goal was to investigate whether subtypes of DSM-IV depression predict suicidal behavior among patients with substance dependence...
  74. ncbi request reprint Alcohol dependence symptoms and alcohol dehydrogenase 2 polymorphism: Israeli Ashkenazis, Sephardics, and recent Russian immigrants
    Deborah Hasin
    Division of Epidemiology, Mailman School of Public Health and the Department of Psychiatry Colle of Physicians and Surgeons, Columbia University, and the New York State Psychiatric Institute, New York, New York 10032, USA
    Alcohol Clin Exp Res 26:1315-21. 2002
    ..We studied the relationship of ADH2*2 to DSM-IV dependence severity in a random community sample of Israeli Ashkenazis, recent Russian immigrants (also Ashkenazis), and Sephardics...
  75. ncbi request reprint Usefulness of plasma haloperidol levels for monitoring clinical efficacy and side effects in Alzheimer patients with psychosis and behavioral dyscontrol
    Gregory H Pelton
    Department of Biological Psychiatry, New York State Psychiatric Institute, New York, NY 10032, USA
    Am J Geriatr Psychiatry 11:186-93. 2003
    ....
  76. ncbi request reprint The relationship between blood lead, bone lead and child intelligence
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, and New York State Pyschiatric Institute, New York City, 10032, USA
    Child Neuropsychol 9:22-34. 2003
    ..1 points, respectively. Bone lead-IQ associations were stronger than those for blood lead, which nonetheless provide robust analogues. Current BPb, easy to obtain, provides a useful means for assessing Pb exposure/IQ associations...
  77. pmc Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh
    Gail A Wasserman
    Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Environ Health Perspect 112:1329-33. 2004
    ..5 microg/L. The association was generally stronger for well-water As than for urinary As...
  78. ncbi request reprint A prospective study of prenatal and childhood lead exposure and erythropoietin production
    Joseph Graziano
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    J Occup Environ Med 46:924-9. 2004
    ..No association was found between tibia Pb and EPO. The continued decline in the slope of the relationship between EPO and BPb with age, after adjustment for hemoglobin, implies a gradually decreasing capacity to produce EPO...
  79. ncbi request reprint Concordance correlation in the measurements of time to event
    Xinhua Liu
    Department of Biostatistics, New York State Psychiatric Institute and Columbia University, New York, NY 10032, USA
    Stat Med 24:1409-20. 2005
    ..The use of the CCC with censored data is illustrated with an example taken from a data set containing data on time to an event with two raters per subject...
  80. pmc Substance use, suicidal ideation and attempts in children and adolescents
    Ping Wu
    Department of Psychiatry, Columbia University, and the New York State Psychiatric Institute, NY 10032, USA
    Suicide Life Threat Behav 34:408-20. 2004
    ..The associations between substance use/abuse and suicidal ideation were no longer significant after controlling for depression. These findings highlight the important role that substance use plays in adolescent suicidal behaviors...
  81. ncbi request reprint The Type A-Type B classification in a community sample of problem drinkers: structural and predictive validity
    Kenneth M Carpenter
    Columbia University College of Physicians and Surgeons, New York State Psychiatric Institute, NY 10032, USA
    Addict Behav 31:15-30. 2006
    ..The present study investigated the Type A/Type B distinction in a community sample of problem drinkers as well as its predictive validity among problem drinkers with no history of alcohol dependence...
  82. ncbi request reprint Fruit and vegetable intake during pregnancy and risk for development of sporadic retinoblastoma
    Manuela A Orjuela
    Department of Pediatrics, Mailman School of Public Health at Columbia University, Room B106, 60 Haven Avenue, New York, New York 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:1433-40. 2005
    ..Fruits and vegetables are important sources of carotenoids and folate. We examined whether decreased gestational maternal intake of fruits and vegetables may contribute to development of sporadic retinoblastoma...
  83. ncbi request reprint Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairment
    D P Devanand
    Department of Biological Psychiatry, New York State Psychiatric Institute, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Arch Neurol 62:975-80. 2005
    ..In cognitively impaired patients without dementia, the utility of apolipoprotein E (APOE) genotyping is unclear...
  84. ncbi request reprint Postdischarge cannabis use and its relationship to cocaine, alcohol, and heroin use: a prospective study
    Efrat Aharonovich
    Division on Substance Abuse, Columbia University, New York, NY 10032, USA
    Am J Psychiatry 162:1507-14. 2005
    ..Because cannabis is a widely used substance, the authors examined whether cannabis use during follow-up after discharge from inpatient treatment affected cocaine, alcohol, and/or heroin use...
  85. ncbi request reprint Cognitive deficits predict low treatment retention in cocaine dependent patients
    Efrat Aharonovich
    College of Physicians and Surgeons, Department of Psychiatry, Columbia University, Division on Substance Abuse, 1051 Riverside Drive, Unit 120, New York, NY 10032, USA
    Drug Alcohol Depend 81:313-22. 2006
    ..Modified behavioral and pharmacologic interventions should be considered to target mild cognitive impairments to improve substance treatment outcome...
  86. pmc Childhood depressive symptoms and early onset of alcohol use
    Ping Wu
    Mailman School of Public Health, Columbia University, New York, New York, USA
    Pediatrics 118:1907-15. 2006
    ....
  87. ncbi request reprint Use of complementary and alternative medicine among women with depression: results of a national survey
    Ping Wu
    Department of Psychiatry, Columbia University, 1051 Riverside Dr, Unit 43, New York, NY 10032, USA
    Psychiatr Serv 58:349-56. 2007
    ....
  88. pmc Classification trees distinguish suicide attempters in major psychiatric disorders: a model of clinical decision making
    J John Mann
    Department of Neuroscience, New York State Psychiatric Institute, New York 10032, USA
    J Clin Psychiatry 69:23-31. 2008
    ..Hypothetical decision trees to identify recent and remote suicide attempters, weighted to increase sensitivity, were generated for psychiatric patients using correlates of past suicidal behavior...
  89. doi request reprint Tremor severity and age: a cross-sectional, population-based study of 2,524 young and midlife normal adults
    Elan D Louis
    GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Mov Disord 26:1515-20. 2011
    ..These data suggest that age-dependent increase in tremor amplitude is not restricted to older people but occurs in all adult age groups...
  90. doi request reprint Ecstasy use and associated risk factors among Asian-American youth: findings from a national survey
    Ping Wu
    Department of Psychiatry, Columbia University, 1051 Riverside Drive, Unit 43, New York, NY 10032, USA
    J Ethn Subst Abuse 10:112-25. 2011
    ..Implications for designing substance use prevention/intervention programs for this minority group are discussed...
  91. pmc Diagnostic delay and sociodemographic predictors of stage at diagnosis and mortality in unilateral and bilateral retinoblastoma
    Marco A Ramirez-Ortiz
    Authors Affiliations Departments of Ophthalmology, Pathology, and Oncology of the Hospital Infantil de Mexico Federico Gomez Hospital de Pediatria, Centro Medico Siglo XXI, Instituto Mexicano de Seguro Social, Mexico City, Mexico Departments of Biostatistics and Environmental Health Sciences and Pediatrics Division of Oncology, Columbia University, New York, New York
    Cancer Epidemiol Biomarkers Prev 23:784-92. 2014
    ..The relationship of diagnostic delay (lag time) and sociodemographic factors on the extent of disease at diagnosis has not been examined separately for unilateral and bilateral retinoblastoma...
  92. doi request reprint Mental health service use among suicidal adolescents: findings from a U.S. national community survey
    Ping Wu
    Department of Psychiatry, Columbia University, New York, NY 10032, USA
    Psychiatr Serv 61:17-24. 2010
    ..This study assessed patterns of mental health service use among adolescents who had attempted suicide and examined factors associated with their service use at individual, family, and community levels...
  93. pmc Elevated brain harmane (1-methyl-9H-pyrido[3,4-b]indole) in essential tremor cases vs. controls
    Elan D Louis
    GH Sergievsky Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY, USA Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA Taub Institute for Research on Alzheimer s Disease and the Aging Brain, College of Physicians and Surgeons, Columbia University, New York, NY, USA Electronic address
    Neurotoxicology 38:131-5. 2013
    ..controls, all work to date has involved blood samples...
  94. pmc Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats
    Bhupendra Singh
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA
    J Biochem Mol Toxicol 23:202-11. 2009
    ..In summary, these data suggest that estrogen-mediated oxidant stress plays a critical role in the development of estrogen-dependent breast cancers and BHA inhibits E(2)-dependent breast carcinogenesis by decreasing oxidant stress...
  95. ncbi request reprint DSM-IV alcohol dependence: a categorical or dimensional phenotype?
    Deborah S Hasin
    Department of Epidemiology, Mailman School of Public Health, Columbia University, NY, USA
    Psychol Med 36:1695-705. 2006
    ..We investigated the validity of DSM-IV alcohol dependence as a dimensional phenotype by examining evidence for linearity and thresholds in associations with validating variables...
  96. pmc Effect of esomeprazole versus placebo on pulmonary exacerbations in cystic fibrosis
    Emily Dimango
    Columbia University Medical Center Department of Medicine, 622 West 168th Street, New York, NY 10032, USA
    BMC Pulm Med 14:21. 2014
    ..Gastro esophageal reflux (GER) is common in cystic fibrosis (CF) and may contribute to lung disease. Approximately 50% of patients with cystic fibrosis are being treated with proton pump inhibitors (PPIs)...
  97. doi request reprint Optimal survival time-related cut-point with censored data
    Xinhua Liu
    Department of Biostatistics, Columbia University, New York, 10032, NY, U S A
    Stat Med 34:515-24. 2015
    ..We apply the procedure to estimate survival time-dependent cut-point on the prognostic biomarker of serum bilirubin among patients with primary biliary cirrhosis...
  98. pmc Oxidative stress biomarkers in sporadic ALS
    Hiroshi Mitsumoto
    Eleanor and Lou Gehrig MDA ALS Research Center, Columbia University Medical Center, New York, NY 10032, USA
    Amyotroph Lateral Scler 9:177-83. 2008
    ..ELISA may be reliable and thus useful in epidemiology studies requiring large numbers of samples to determine the significance of increased oxidative stress markers in SALS. Further studies are required...
  99. pmc Classic respiratory disease but atypical diagnostic testing distinguishes adult presentation of cystic fibrosis
    Claire L Keating
    Columbia University Medical Center, 622 W 168th St, PH 8, New York, NY 10032, USA
    Chest 137:1157-63. 2010
    ..We compare newly diagnosed CF in adults with newly diagnosed CF in children and adolescents in the United States...
  100. pmc Prenatal exposure to polychlorinated biphenyls and postnatal growth: a structural analysis
    Matthew R Lamb
    Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
    Environ Health Perspect 114:779-85. 2006
    ..Although limited by sample size, our results suggest that prenatal exposure to PCBs may affect growth, especially in girls, and that ortho-substitution is an important determinant of its effect on growth...
  101. ncbi request reprint Chromosomal aberrations in cord blood are associated with prenatal exposure to carcinogenic polycyclic aromatic hydrocarbons
    Kirsti A Bocskay
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, B 109, New York, NY 10032, USA
    Cancer Epidemiol Biomarkers Prev 14:506-11. 2005
    ..If confirmed, this finding may open new avenues for prevention...