Affiliation: Columbia University
- Roles of the Akt/GSK-3 and Wnt signaling pathways in schizophrenia and antipsychotic drug actionZachary Freyberg
Department of Psychiatry, Center for Molecular Recognition, College of Physicians and Surgeons, Columbia University, NY 10032, USA
Am J Psychiatry 167:388-96. 2010..Further study of Akt/GSK-3 and Wnt signaling may ultimately lead to alternative therapeutics of schizophrenia-related disorders...
- Molecular pathophysiology of metabolic effects of antipsychotic medicationsJacob S Ballon
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA Division of Experimental Therapeutics, New York State Psychiatric Institute, New York, NY 10032, USA
Trends Endocrinol Metab 25:593-600. 2014....
- Signaling pathways in schizophrenia: emerging targets and therapeutic strategiesCaline S Karam
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Trends Pharmacol Sci 31:381-90. 2010..These include genes in the 22q11 locus, DISC1, Neuregulin 1/ErbB4, and components of the Akt/GSK-3 pathway...
- Mechanisms of amphetamine action illuminated through optical monitoring of dopamine synaptic vesicles in Drosophila brainZachary Freyberg
Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
Nat Commun 7:10652. 2016..Thus, we find that at pharmacologically relevant concentrations, amphetamines must be actively transported by DAT and VMAT in tandem to produce psychostimulant effects. ..