G S Francis

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. ncbi request reprint Acute heart failure: patient management of a growing epidemic
    Gary S Francis
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F25, Cleveland, OH 44195, USA
    Am Heart Hosp J 2:10-4. 2004
  2. ncbi request reprint Acute decompensated heart failure: the cardiorenal syndrome
    Gary Francis
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Cleve Clin J Med 73:S8-13; discussion S30-3. 2006
  3. ncbi request reprint The looming polypharmacy crisis in the management of patients with heart failure. Potential solutions
    G S Francis
    Coronary Intensive Care Unit, Department of Cardiology, George M and Linda H Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Cardiol Clin 19:541-5. 2001
  4. ncbi request reprint Cardiac troponins in renal insufficiency and other non-ischemic cardiac conditions
    Gary S Francis
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, F25, Cleveland, Ohio 44195, USA
    Prog Cardiovasc Dis 47:196-206. 2004
  5. ncbi request reprint Pathophysiology of chronic heart failure
    G S Francis
    George M. and Linda H. Kaufman Center for Heart Failure, Department of Cardiology, The Cleveland Clinic Foundation, OH 44195, USA
    Am J Med 110:37S-46S. 2001
  6. ncbi request reprint Impaired chronotropic response to exercise stress testing as a predictor of mortality
    M S Lauer
    Department of Cardiology, The George M and Linda H Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Ohio 44195, USA
    JAMA 281:524-9. 1999
  7. ncbi request reprint Cardiac troponins and chronic kidney disease
    A S Kanderian
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation Desk F15, Cleveland, Ohio 44195, USA
    Kidney Int 69:1112-4. 2006
  8. ncbi request reprint Polypharmacy of heart failure. Creating a rational pharmacotherapeutic protocol
    W H Tang
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Cardiol Clin 19:583-96, viii. 2001
  9. ncbi request reprint Clinical outcomes of patients with impaired left ventricular ejection fraction undergoing autologous bone marrow transplantation: can we safely transplant patients with impaired ejection fraction?
    W H W Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Kaufman Center for Heart Failure, Cleveland, OH, USA
    Bone Marrow Transplant 34:603-7. 2004
  10. ncbi request reprint Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays
    J Yang
    Department of Molecular Cardiology, Center for Anesthesiology Research, Lerner Research Institute, Cleveland, Ohio, USA
    Circulation 102:3046-52. 2000

Collaborators

Detail Information

Publications69

  1. ncbi request reprint Acute heart failure: patient management of a growing epidemic
    Gary S Francis
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk F25, Cleveland, OH 44195, USA
    Am Heart Hosp J 2:10-4. 2004
    ..Prevention of acute heart failure by avoiding factors known to precipitate decompensation remains the most cost-effective strategy...
  2. ncbi request reprint Acute decompensated heart failure: the cardiorenal syndrome
    Gary Francis
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA
    Cleve Clin J Med 73:S8-13; discussion S30-3. 2006
    ..Patients with decompensated heart failure are often refractory to diuretics, in which case higher doses must be used or alternate methods explored to reduce salt and water...
  3. ncbi request reprint The looming polypharmacy crisis in the management of patients with heart failure. Potential solutions
    G S Francis
    Coronary Intensive Care Unit, Department of Cardiology, George M and Linda H Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Cardiol Clin 19:541-5. 2001
    ..This will not be an easy task, but the current model of rational drug development followed by a large megatrial is costly and not likely to be sustained indefinitely...
  4. ncbi request reprint Cardiac troponins in renal insufficiency and other non-ischemic cardiac conditions
    Gary S Francis
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, F25, Cleveland, Ohio 44195, USA
    Prog Cardiovasc Dis 47:196-206. 2004
    ..Last, monitoring cardiac troponins in cardiac transplant recipients and those receiving certain cardiotoxic chemotherapies may be of some diagnostic value, but clearly more experience and clinical research are needed...
  5. ncbi request reprint Pathophysiology of chronic heart failure
    G S Francis
    George M. and Linda H. Kaufman Center for Heart Failure, Department of Cardiology, The Cleveland Clinic Foundation, OH 44195, USA
    Am J Med 110:37S-46S. 2001
    ....
  6. ncbi request reprint Impaired chronotropic response to exercise stress testing as a predictor of mortality
    M S Lauer
    Department of Cardiology, The George M and Linda H Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Ohio 44195, USA
    JAMA 281:524-9. 1999
    ..Chronotropic incompetence, an attenuated heart rate response to exercise, is a predictor of all-cause mortality in healthy populations. This association may be independent of exercise-induced myocardial perfusion defects...
  7. ncbi request reprint Cardiac troponins and chronic kidney disease
    A S Kanderian
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation Desk F15, Cleveland, Ohio 44195, USA
    Kidney Int 69:1112-4. 2006
    ..A distinct rise and fall in the levels over baseline strongly support the diagnosis of acute myocardial necrosis. Despite uncertainties regarding increased troponins in patients with CKD, their value remains clear...
  8. ncbi request reprint Polypharmacy of heart failure. Creating a rational pharmacotherapeutic protocol
    W H Tang
    Department of Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Cardiol Clin 19:583-96, viii. 2001
    ....
  9. ncbi request reprint Clinical outcomes of patients with impaired left ventricular ejection fraction undergoing autologous bone marrow transplantation: can we safely transplant patients with impaired ejection fraction?
    W H W Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Kaufman Center for Heart Failure, Cleveland, OH, USA
    Bone Marrow Transplant 34:603-7. 2004
    ..As medical care for HF and ABMT improves, the exclusion criteria for ABMT with regard to HF and impaired LVEF should be re-examined...
  10. ncbi request reprint Decreased SLIM1 expression and increased gelsolin expression in failing human hearts measured by high-density oligonucleotide arrays
    J Yang
    Department of Molecular Cardiology, Center for Anesthesiology Research, Lerner Research Institute, Cleveland, Ohio, USA
    Circulation 102:3046-52. 2000
    ..Thus, expression of multiple classes of genes is likely to be altered in human heart failure...
  11. ncbi request reprint Enhanced external counterpulsation improves exercise duration and peak oxygen consumption in older patients with heart failure: a subgroup analysis of the PEECH trial
    Charles W Abbottsmith
    The Ohio Heart and Vascular Center, Cincinnati, OH 45219, USA
    Congest Heart Fail 12:307-11. 2006
    ..017). The authors conclude that an older subgroup of PEECH subjects confirms the beneficial effect of EECP in patients with chronic, stable, mild-to-moderate heart failure...
  12. ncbi request reprint Enhanced external counterpulsation improves exercise tolerance in patients with chronic heart failure
    Arthur M Feldman
    Department of Medicine, Jefferson Medical College, Philadelphia, Pennsylvania, USA
    J Am Coll Cardiol 48:1198-205. 2006
    ....
  13. pmc Heart failure, chronic diuretic use, and increase in mortality and hospitalization: an observational study using propensity score methods
    Ali Ahmed
    Department of Medicine, School of Medicine, and Department of Epidemiology, School of Public Health, and Center for Heart Failure Research, University of Alabama at Birmingham and VA Medical Center, 35294 2041, USA
    Eur Heart J 27:1431-9. 2006
    ..Yet, the long-term effects of chronic diuretic use in HF are largely unknown. We retrospectively analysed the Digitalis Investigation Group (DIG) data to determine the effects of diuretics on HF outcomes...
  14. ncbi request reprint Vasopressin receptor antagonists in the management of acute heart failure
    W H Wilson Tang
    Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Expert Opin Investig Drugs 14:593-600. 2005
    ..Nevertheless, their comparative long-term safety and efficacy remains to be determined in large-scale clinical trials...
  15. ncbi request reprint Aldosterone receptor antagonists in the medical management of chronic heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, OH 44195, USA
    Mayo Clin Proc 80:1623-30. 2005
    ..Theoretically, aldosterone receptor antagonists may also be beneficial in patients with more mild to moderate systolic heart failure or even in those with diastolic heart failure, although direct evidence is still lacking...
  16. ncbi request reprint Evaluation study of congestive heart failure and pulmonary artery catheterization effectiveness: the ESCAPE trial
    Cynthia Binanay
    Duke Clinical Research Institute, Durham, NC, USA
    JAMA 294:1625-33. 2005
    ..Pulmonary artery catheters (PACs) have been used to guide therapy in multiple settings, but recent studies have raised concerns that PACs may lead to increased mortality in hospitalized patients...
  17. ncbi request reprint Comparative sensitivities between different plasma B-type natriuretic peptide assays in patients with minimally symptomatic heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Section of Heart Failure and Cardiac Transplantation Medicine, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Clin Cornerstone 7:S18-24. 2005
    ..These findings suggest that there is a relationship between the decision statistics used in screening for left ventricular dysfunction and the type of diagnostic assay used...
  18. ncbi request reprint Pathophysiologic targets in the early phase of acute heart failure syndromes
    Mihai Gheorghiade
    Division of Cardiology, Northwester University Feinberg School of Medicine, Chicago, Illinois 60611, USA
    Am J Cardiol 96:11G-17G. 2005
    ..The goals of therapy for AHFS should be not only to improve symptoms and hemodynamics, but also to preserve or improve renal function and prevent myocardial damage...
  19. ncbi request reprint The difficult task of evaluating how to monitor patients with heart failure
    W H Wilson Tang
    J Card Fail 11:422-4. 2005
  20. ncbi request reprint The year in heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 48:2575-83. 2006
  21. ncbi request reprint Risk stratification for patients undergoing nonurgent percutaneous coronary intervention using N-terminal pro-B-type natriuretic peptide: a Clopidogrel for the Reduction of Events During Observation (CREDO) substudy
    W H Wilson Tang
    Department of Cardiovascular Medicine, The Cleveland Clinic, Cleveland, OH 44195, USA
    Am Heart J 153:36-41. 2007
    ..The comparative prognostic values between NT-proBNP levels and left ventricular ejection fraction (LVEF) in the nonurgent PCI setting are unclear...
  22. doi request reprint Sodium nitroprusside for advanced low-output heart failure
    Wilfried Mullens
    Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 52:200-7. 2008
    ..This study was designed to examine the safety and efficacy of sodium nitroprusside (SNP) for patients with acute decompensated heart failure (ADHF) and low-output states...
  23. doi request reprint From B-type natriuretic peptide to green mambas: the process of discovery
    Gary S Francis
    J Am Coll Cardiol 52:69-70. 2008
  24. doi request reprint Impact of myocardial function on cystatin C measurements in chronic systolic heart failure
    W H Wilson Tang
    Kaufman Center for Heart Failure, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland Ohio 44195, USA
    J Card Fail 14:394-9. 2008
    ..The influence of myocardial function on plasma levels of cystatin C (CysC), a sensitive marker of renal function, in chronic systolic heart failure (HF) has not been well established...
  25. doi request reprint Racial analysis of patients with myocardial infarction complicated by heart failure and/or left ventricular dysfunction treated with valsartan, captopril, or both
    L Michael Prisant
    Hypertension and Clinical Pharmacology, Medical College of Georgia, Augusta, Georgia 30912, USA
    J Am Coll Cardiol 51:1865-71. 2008
    ....
  26. doi request reprint Prognostic evaluation of ambulatory patients with advanced heart failure
    Wilfried Mullens
    Department of Cardiovascular Medicine, Kaufman Center for Heart Failure, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 101:1297-302. 2008
    ..0001). In conclusion, in ambulatory patients with advanced HF, hemodynamic and renal function assessments remain strong independent predictors of all-cause mortality...
  27. doi request reprint Outcomes of patients with stable heart failure undergoing elective noncardiac surgery
    Ye Olivia Xu-Cai
    Department of Hospital Medicine, The Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Mayo Clin Proc 83:280-8. 2008
    ....
  28. doi request reprint Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: a VALIANT study
    Eldrin F Lewis
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Eur Heart J 29:748-56. 2008
    ..We sought to assess the incidence of and prognostic factors for heart failure (HF) hospitalization among survivors of high-risk acute myocardial infarction (MI)...
  29. doi request reprint Evaluation and long-term prognosis of new-onset, transient, and persistent anemia in ambulatory patients with chronic heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 51:569-76. 2008
    ..This study sought to determine the characteristics and long-term prognosis of anemia in ambulatory patients with chronic heart failure...
  30. doi request reprint Elevated intra-abdominal pressure in acute decompensated heart failure: a potential contributor to worsening renal function?
    Wilfried Mullens
    Section of Heart Failure and Cardiac Transplantation, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 51:300-6. 2008
    ..This study sought to determine whether changes in intra-abdominal pressure (IAP) with aggressive diuretic or vasodilator therapy are associated with improvement in renal function in acute decompensated heart failure (ADHF)...
  31. ncbi request reprint National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical utilization of cardiac biomarker testing in heart failure
    W H Wilson Tang
    Cleveland Clinic, Foundation, Cleveland, OH, USA
    Clin Biochem 41:210-21. 2008
  32. ncbi request reprint National Academy of Clinical Biochemistry Laboratory Medicine practice guidelines: Clinical utilization of cardiac biomarker testing in heart failure
    W H Wilson Tang
    Circulation 116:e99-109. 2007
  33. ncbi request reprint Drug insight: aldosterone-receptor antagonists in heart failure--the journey continues
    Srinivasa R Kalidindi
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA
    Nat Clin Pract Cardiovasc Med 4:368-78. 2007
    ....
  34. pmc Detection of soluble angiotensin-converting enzyme 2 in heart failure: insights into the endogenous counter-regulatory pathway of the renin-angiotensin-aldosterone system
    Slava Epelman
    Department of Internal Medicine, Heart and Vascular Institute, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 52:750-4. 2008
    ..We sought to determine whether circulating soluble angiotensin-converting enzyme 2 (sACE2) is increased in the plasma of patients with heart failure (HF)...
  35. ncbi request reprint Neurohormonal upregulation in heart failure
    W H Wilson Tang
    Case Western Reserve University, Cleveland, OH, USA
    Heart Fail Clin 1:1-9. 2005
  36. ncbi request reprint Why do patients fail to receive beta-blockers for chronic heart failure over time? A "real-world" single-center, 2-year follow-up experience of beta-blocker therapy in patients with chronic heart failure
    Anoop C Parameswaran
    Department of Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am Heart J 149:921-6. 2005
    ..The long-term compliance rate for beta-blocker drugs outside the context of a clinical trial has not been established...
  37. ncbi request reprint Heart rate response during dipyridamole stress as a predictor of mortality in patients with normal myocardial perfusion and normal electrocardiograms
    Rohit Bhatheja
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Cardiol 95:1159-64. 2005
    ..Thus, among patients who have normal myocardial perfusion and normal electrocardiograms, a blunted heart rate response to vasodilator stress is predictive of a marked increase in risk of death...
  38. ncbi request reprint Plasma B-type natriuretic peptide levels in ambulatory patients with established chronic symptomatic systolic heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Circulation 108:2964-6. 2003
    ..The diagnostic and prognostic values of plasma B-type natriuretic peptide (BNP) testing are established. However, the range of plasma BNP levels present in the setting of chronic, stable systolic heart failure (HF) is unclear...
  39. ncbi request reprint Novel pharmacological treatments for heart failure
    W H Wilson Tang
    Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Expert Opin Investig Drugs 12:1791-801. 2003
    ....
  40. ncbi request reprint Aspirin and clopidogrel in acute coronary syndromes: therapeutic insights from the CURE study
    Hani Jneid
    Division of Cardiology, University of Louisville, Louisville, KY, USA
    Arch Intern Med 163:1145-53. 2003
    ..Aspirin resistance can be assessed through platelet aggregometry testing, measurement of urinary thromboxane metabolites, and, possibly, genomic testing in the future...
  41. ncbi request reprint Nitroprusside in critically ill patients with left ventricular dysfunction and aortic stenosis
    Umesh N Khot
    Indiana Heart Physicians, Indianapolis 46107, USA
    N Engl J Med 348:1756-63. 2003
    ..However, vasodilators such as nitroprusside may improve myocardial performance if peripheral vasoconstriction is contributing to afterload...
  42. ncbi request reprint Fluid retention after initiation of thiazolidinedione therapy in diabetic patients with established chronic heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Coll Cardiol 41:1394-8. 2003
    ..We sought to define the characteristics of fluid retention after thiazolidinedione (TZD) initiation in patients with established heart failure (HF)...
  43. ncbi request reprint Beta-blockers and reverse remodeling: what are the implications?
    Gary S Francis
    Am Heart J 145:200-2. 2003
  44. ncbi request reprint Cardiac troponins in renal insufficiency: review and clinical implications
    Benjamin J Freda
    Department of Internal Medicine, Cleveland Clinic Foundation, Ohio 44195, USA
    J Am Coll Cardiol 40:2065-71. 2002
    ..It is possible that increases in serum troponin from baseline in patients with renal insufficiency admitted to hospital with acute coronary syndrome may signify myocardial necrosis. Further studies are needed to clarify this hypothesis...
  45. ncbi request reprint The prognostic value of estimated creatinine clearance alongside functional capacity in ambulatory patients with chronic congestive heart failure
    Niall G Mahon
    Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 40:1106-13. 2002
    ..The goal of this study was to determine the prognostic significance of estimated creatinine clearance (CrCl) in relation to 6-min walk distance in ambulatory patients with congestive heart failure (HF)...
  46. ncbi request reprint Pathophysiology of congestive heart failure
    Gary S Francis
    George M and Linda H Kaufman Center for Heart Failure, Cleveland Clinic Foundation, Cleveland, OH, USA
    Rev Cardiovasc Med 4:S14-20. 2003
    ..More emphasis should be placed on recognition and correction of risk factors related to the development of heart failure...
  47. ncbi request reprint Ask Dr. Francis. I read recently that people with diabetes are at high risk for cardiovascular disease. I have diabetes, but am not aware of any other health problems. What can I do to reduce my risk?
    Gary S Francis
    Heart Advis 5:8. 2002
  48. ncbi request reprint Induction and maintenance of an experimental model of severe cardiomyopathy with a novel protocol of rapid ventricular pacing
    Masami Takagaki
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Thorac Cardiovasc Surg 123:544-9. 2002
    ..The purpose of this study was to evaluate a unique new model of severe heart failure developed by means of a novel protocol of rapid ventricular pacing...
  49. ncbi request reprint In heart failure, all beta-blockers are not necessarily equal
    W H Wilson Tang
    The George M and Linda H Kaufman Center for Heart Failure, Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, OH 44195, USA
    Cleve Clin J Med 70:1081-7. 2003
    ..Given the overwhelming evidence of the benefit of carvedilol, metoprolol succinate, and bisoprolol in patients with heart failure, we should all strive to increase the use of these drugs in appropriate doses...
  50. ncbi request reprint Plasma B-type natriuretic peptide levels predict postoperative atrial fibrillation in patients undergoing cardiac surgery
    Oussama M Wazni
    Center for Atrial Fibrillation, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Circulation 110:124-7. 2004
    ..Recently, B-type natriuretic peptide (BNP) has been reported to predict occurrence of nonpostoperative AF. This study evaluates whether elevated preoperative (preop) plasma BNP levels predict the occurrence of postop AF...
  51. ncbi request reprint Neurohormonal response to left ventricular reconstruction surgery in ischemic cardiomyopathy
    Soren Schenk
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Thorac Cardiovasc Surg 128:38-43. 2004
    ..We evaluated the neurohormonal response to left ventricular reconstruction surgery in ischemic cardiomyopathy...
  52. ncbi request reprint The year in heart failure
    W H Wilson Tang
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 46:2125-33. 2005
  53. ncbi request reprint Treating heart failure with enhanced external counterpulsation (EECP): design of the Prospective Evaluation of EECP in Heart Failure (PEECH) trial
    Arthur M Feldman
    Department of Medicine, Jefferson Medical College, 1025 Walnut Street, Philadelphia, PA 19607, USA
    J Card Fail 11:240-5. 2005
    ..Thus a larger, controlled study of EECP in patients with stable HF (New York Heart Association [NYHA] classes II and III) and LVD was undertaken...
  54. ncbi request reprint Trends and treatment of heart failure developing after acute myocardial infarction
    W H Wilson Tang
    Kaufman Center for Heart Failure, Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart Hosp J 1:216-8. 2003
    ....
  55. ncbi request reprint Angiotensin-converting enzyme inhibitors and angiotensin-receptor blockers in chronic heart failure
    Mark B McClellan
    Ann Intern Med 142:386-7; author reply 388-9. 2005
  56. ncbi request reprint An international perspective on heart failure and left ventricular systolic dysfunction complicating myocardial infarction: the VALIANT registry
    Eric J Velazquez
    Division of Cardiology, Department of Medicine, Duke University Medical Center and Duke Clinical Research Institute, P O Box 17969, Durham, NC 27715, USA
    Eur Heart J 25:1911-9. 2004
    ....
  57. ncbi request reprint A hard look at angiotensin receptor blockers in heart failure
    Christian N Gring
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    J Am Coll Cardiol 44:1841-6. 2004
    ..Angiotensin receptor blockers should be reserved for monotherapy in ACE intolerant patients and for combination therapy in symptomatic class II/III patients with chronic heart failure...
  58. ncbi request reprint Testing for B-type natriuretic peptide in the diagnosis and assessment of heart failure: what are the nuances?
    James B Young
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Ohio 44195, USA
    Cleve Clin J Med 71:S1-17. 2004
  59. ncbi request reprint Newly diagnosed and previously known diabetes mellitus and 1-year outcomes of acute myocardial infarction: the VALsartan In Acute myocardial iNfarcTion (VALIANT) trial
    David Aguilar
    Cardiovascular Division, University of Texas Health Science Center, 6431 Fannin, MSB 1 246, Houston, TX 77030, USA
    Circulation 110:1572-8. 2004
    ..A prior diagnosis of diabetes mellitus is associated with adverse outcomes after acute myocardial infarction (MI), but the risk associated with a new diagnosis of diabetes in this setting has not been well defined...
  60. ncbi request reprint Predictors of mortality in patients with heart failure and preserved systolic function in the Digitalis Investigation Group trial
    R Christopher Jones
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Am Coll Cardiol 44:1025-9. 2004
    ..We identified predictors of mortality in patients with preserved ejection fraction (EF) and clinical heart failure (HF)...
  61. ncbi request reprint Effects of sodium nitroprusside in aortic stenosis associated with severe heart failure: pressure-volume loop analysis using a numerical model
    Zoran B Popovic
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Heart Circ Physiol 288:H416-23. 2005
    ..In conclusion, using a numerical model, we identified ventricular function parameters that are responsible for improved hemodynamics during SNP infusion in AS with LV dysfunction...
  62. ncbi request reprint ACC/AHA guidelines for the evaluation and management of chronic heart failure in the adult: executive summary
    Sharon A Hunt
    American College of Cardiology American Heart Association Task Force on Practice Guidelines
    J Heart Lung Transplant 21:189-203. 2002
  63. ncbi request reprint Ask Dr. Francis. I am taking a medication called rofecoxib for knee arthritis, and it works well. But I've heard reports that this type of medication may be dangerous for people with heart disease. Should I be worried?
    Gary S Francis
    Heart Advis 5:8. 2002
  64. ncbi request reprint Combining neuroendocrine inhibitors in heart failure: reflections on safety and efficacy
    Hani Jneid
    Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Am J Med 120:1090.e1-8. 2007
    ..Close follow-up and implementation of evidence-based medicine (ie, using agents and doses proven beneficial in clinical trials) should therefore be undertaken when combining neuroendocrine inhibitors...
  65. ncbi request reprint I have been told that I have very weak heart muscle that is causing heart failure. I saw a special on television about implantable pumps. Could one of these help me?
    Gary S Francis
    Heart Advis 5:8. 2002
  66. ncbi request reprint Characterization and prognostic value of persistent hyponatremia in patients with severe heart failure in the ESCAPE Trial
    Mihai Gheorghiade
    Division of Cardiology, Northwestern University, Feinberg School of Medicine, 201 E Huron Street, Chicago, IL 60611, USA
    Arch Intern Med 167:1998-2005. 2007
    ..To our knowledge, the association of hyponatremia with outcomes has not been evaluated in the context of in-hospital clinical course including central hemodynamics and changes in serum sodium level...
  67. ncbi request reprint Should we consider aldosterone as the primary screening target for preventing cardiovascular events?
    Gary S Francis
    J Am Coll Cardiol 45:1249-50. 2005
  68. ncbi request reprint Anemia and heart failure a new pathway?
    Gary S Francis
    J Am Coll Cardiol 50:1666-7. 2007
  69. ncbi request reprint Natriuretic peptides and renal insufficiency: clinical significance and role of renal clearance
    Benjamin J Freda
    Tufts University School of Medicine, Baystate Medical Center, Springfield, MA, USA
    Heart Fail Clin 2:277-90. 2006