Xi Chen

Summary

Affiliation: Cleveland Clinic Foundation
Country: USA

Publications

  1. pmc Integrating biological knowledge with gene expression profiles for survival prediction of cancer
    Xi Chen
    Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Comput Biol 16:265-78. 2009
  2. pmc Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes
    Xi Chen
    Department of Quantitative Health Sciences, The Cleveland Clinic, 9500 Euclid Ave Cleveland, OH 44195, USA
    Bioinformatics 24:2474-81. 2008
  3. doi request reprint Improved time-zero biomechanical properties using poly-L-lactic acid graft augmentation in a cadaveric rotator cuff repair model
    Jesse A McCarron
    Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
    J Shoulder Elbow Surg 19:688-96. 2010
  4. pmc An integrated approach for the analysis of biological pathways using mixed models
    Lily Wang
    Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Genet 4:e1000115. 2008
  5. pmc Wnt signaling: the good and the bad
    Xi Chen
    Sealy Center for Cancer Cell Biology, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555 1048, USA
    Acta Biochim Biophys Sin (Shanghai) 40:577-94. 2008
  6. ncbi request reprint Error analysis of calibration materials on dual-energy mammography
    Xuanqin Mou
    Institute of Image Processing and Pattern Recognition, Xi an Jiaotong University Xi an, Shaanxi 710049, China
    Med Image Comput Comput Assist Interv 10:596-603. 2007
  7. ncbi request reprint Recognizing falls from silhouettes
    Derek Anderson
    Dept of Electr and Comput Eng, Missouri Univ, Columbia, MO 65203, USA
    Conf Proc IEEE Eng Med Biol Soc 1:6388-91. 2006
  8. ncbi request reprint A conserved G protein (Drg1p) plays a role in regulation of invasive filamentation in Candida albicans
    Xi Chen
    Department of Molecular Biology and Microbiology, and Genetics Program, Tufts University School of Medicine, Boston, MA 02111, USA
    Microbiology 152:3691-700. 2006
  9. ncbi request reprint Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection
    Synan Abuqamar
    Department of Botany and Plant Pathology, Purdue University, 915 West State Street, West Lafayette, IN 47907 2054, USA
    Plant J 48:28-44. 2006
  10. ncbi request reprint A novel high-throughput genetic screen for stress-responsive mutants of Arabidopsis thaliana reveals new loci involving stress responses
    S Rama Devi
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Plant J 47:652-63. 2006

Collaborators

  • Lily Wang
  • Bing Zhang
  • Joseph P Iannotti
  • Jonathan Smith
  • Paul M Evans
  • C Norman Coleman
  • Fumiaki Katagiri
  • Jun Yang
  • Jesse A McCarron
  • Eric Y Chuang
  • Mong Hsun Tsai
  • Xuanqin Mou
  • Derek Anderson
  • S Rama Devi
  • Synan Abuqamar
  • Hailing Yan
  • James B Mitchell
  • Zuo Liang Chen
  • Zi Liu
  • Wenqiong Chen
  • Paul F Wilson
  • John Salmeron
  • Markus M Fitzek
  • James M Keller
  • Rahul Dhawan
  • Chuan Yuan Li
  • Stephen Lam
  • Chengbin Xiang
  • Joel S Bedford
  • David J Oliver
  • Tesfaye Mengiste
  • John B Little
  • Yuanlin Peng
  • Zhihai He
  • Marjorie Skubic
  • Hatsumi Nagasawa
  • Robert A Dietrich
  • Burton Bluhm
  • G V R Chandramouli
  • Deborah Coffin
  • Shuping Zhao
  • Jin Chun Chen
  • Yu Qin Guan
  • Brigitte Mauch-Mani
  • Felix Mauch
  • Zhiyi Xie
  • Kappei Kobayashi
  • Manfred Heinlein
  • Yi Tao
  • Steve A Whitham
  • Thomas Hohn
  • Jeffery F Harper
  • Jeffery L Dangl
  • Jane Glazebrook
  • Joel A Kreps
  • Paul R Budworth
  • Azzedine Si-Ammour
  • Tong Zhu
  • Nicholas J Provart
  • Hur Song Chang
  • Steve Lam
  • Guangzhou Zou
  • Thomas Eulgem
  • Sheng Luan
  • Xun Wang

Detail Information

Publications16

  1. pmc Integrating biological knowledge with gene expression profiles for survival prediction of cancer
    Xi Chen
    Department of Quantitative Health Sciences, The Cleveland Clinic, Cleveland, OH 44195, USA
    J Comput Biol 16:265-78. 2009
    ....
  2. pmc Supervised principal component analysis for gene set enrichment of microarray data with continuous or survival outcomes
    Xi Chen
    Department of Quantitative Health Sciences, The Cleveland Clinic, 9500 Euclid Ave Cleveland, OH 44195, USA
    Bioinformatics 24:2474-81. 2008
    ..PCA is an effective method for reducing high dimensionality and capture variations in gene expression values. However, one limitation with PCA is that the latent variable identified by the first PC may be unrelated to outcome...
  3. doi request reprint Improved time-zero biomechanical properties using poly-L-lactic acid graft augmentation in a cadaveric rotator cuff repair model
    Jesse A McCarron
    Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
    J Shoulder Elbow Surg 19:688-96. 2010
    ..This study was designed to determine whether application of a woven poly-L-lactic acid device (X-Repair; Synthasome, San Diego, CA) would improve the mechanical properties of rotator cuff repair in vitro...
  4. pmc An integrated approach for the analysis of biological pathways using mixed models
    Lily Wang
    Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, United States of America
    PLoS Genet 4:e1000115. 2008
    ..We compare the properties of this mixed models approach with nonparametric method GSEA and parametric method PAGE using a simulation study, and illustrate its application with a diabetes data set and a dose-response data set...
  5. pmc Wnt signaling: the good and the bad
    Xi Chen
    Sealy Center for Cancer Cell Biology, Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, 301 University Blvd, Galveston, Texas 77555 1048, USA
    Acta Biochim Biophys Sin (Shanghai) 40:577-94. 2008
    ..In this review, we will discuss in detail the functions of many components involved in the Wnt signal transduction pathway. Then, we will explore what is known about the role of Wnt signaling in stem cells and cancers...
  6. ncbi request reprint Error analysis of calibration materials on dual-energy mammography
    Xuanqin Mou
    Institute of Image Processing and Pattern Recognition, Xi an Jiaotong University Xi an, Shaanxi 710049, China
    Med Image Comput Comput Assist Interv 10:596-603. 2007
    ..The evaluation of several popular phantoms shows that it is of great importance to adopt the phantom materials approaching human breast most...
  7. ncbi request reprint Recognizing falls from silhouettes
    Derek Anderson
    Dept of Electr and Comput Eng, Missouri Univ, Columbia, MO 65203, USA
    Conf Proc IEEE Eng Med Biol Soc 1:6388-91. 2006
    ..In this paper, we present preliminary results that demonstrate the usefulness of this approach for distinguishing between a few common activities, specifically with fall detection in mind...
  8. ncbi request reprint A conserved G protein (Drg1p) plays a role in regulation of invasive filamentation in Candida albicans
    Xi Chen
    Department of Molecular Biology and Microbiology, and Genetics Program, Tufts University School of Medicine, Boston, MA 02111, USA
    Microbiology 152:3691-700. 2006
    ..These results implicate Drg1p in the control of invasive filamentation in the laboratory, and in the progression of invasive disease in the host...
  9. ncbi request reprint Expression profiling and mutant analysis reveals complex regulatory networks involved in Arabidopsis response to Botrytis infection
    Synan Abuqamar
    Department of Botany and Plant Pathology, Purdue University, 915 West State Street, West Lafayette, IN 47907 2054, USA
    Plant J 48:28-44. 2006
    ....
  10. ncbi request reprint A novel high-throughput genetic screen for stress-responsive mutants of Arabidopsis thaliana reveals new loci involving stress responses
    S Rama Devi
    Department of Genetics, Development and Cell Biology, Iowa State University, Ames, IA 50011, USA
    Plant J 47:652-63. 2006
    ..The phenotype observed with the Delta8L4 mutant was further verified using RNAi plants for At4g24275 (8L4-RNAi), suggesting the feasibility of use of this high-throughput mutant screening in isolating stress-signaling mutants...
  11. ncbi request reprint Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma
    Eric Y Chuang
    Radiation Biology and Oncology Branches, Center for Cancer Research, National Cancer Institute NIH, Bethesda, MD, USA
    Cancer Res 66:3428-33. 2006
    ..Further study of this phenomenon may offer a new insight into the genetic mechanisms of Rb and perhaps more broadly in cancer biology...
  12. ncbi request reprint Evaluation of hybridization conditions for spotted oligonucleotide-based DNA microarrays
    Mong Hsun Tsai
    Radiation Oncology Sciences Program, Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 8717 Grovemont Cr, Room 109J, Gaithersburg, MD 20878, USA
    Mol Biotechnol 29:221-4. 2005
    ..Statistical analysis showed that better results were obtained when spotted, presynthesized long oligonucleotide arrays were blocked with succinic anhydride and hybridized at 42 degrees C in the presence of 50% formamide...
  13. ncbi request reprint [Effect of Chinese herbal medicine 1023 Recipe in blocking cancer transformation of experimental precancerous lesion and its mechanism]
    Zuo Liang Chen
    Xiamen Hospital of Stomatalogy, Xiamen, Fujian Province 361001, China
    Zhong Xi Yi Jie He Xue Bao 2:281-4. 2004
    ..To study the effect of Chinese herbal medicine 1023 Recipe in blocking cancer transformation of experimental oral precancerous lesion and its mechanism...
  14. ncbi request reprint Glucuronides in anti-cancer therapy
    Xi Chen
    Department of Chemistry, Wayne State University, Detroit, MI 48202, USA
    Curr Med Chem Anticancer Agents 3:139-50. 2003
    ..The prodrugs can also be utilized to modify liposomes for efficient delivery of anti-cancer drugs...
  15. ncbi request reprint [Preliminary results of intraoperative radiation therapy for cervical carcinoma IIb]
    Zi Liu
    Department of Radiation Oncology, First Hospital, Xi an Jiaotong University, Xi an 710061, China
    Zhonghua Fu Chan Ke Za Zhi 37:553-5. 2002
    ..To assess the effects of intraoperative radiation therapy (IORT) for cervical carcinoma IIb...
  16. pmc Expression profile matrix of Arabidopsis transcription factor genes suggests their putative functions in response to environmental stresses
    Wenqiong Chen
    Torrey Mesa Research Institute, Syngenta Research and Technology, 3115 Merryfield Row, San Diego, California 92121, USA
    Plant Cell 14:559-74. 2002
    ....