Lucas C Parra

Summary

Affiliation: City University of New York
Country: USA

Publications

  1. ncbi request reprint Recipes for the linear analysis of EEG
    Lucas C Parra
    Department of Biomedical Engineering, City College of New York, New York, NY 10031, USA
    Neuroimage 28:326-41. 2005
  2. ncbi request reprint Model of the effect of extracellular fields on spike time coherence
    Lucas C Parra
    Department of Biomedical Engineering, City College of New York, NY 10031, USA
    Conf Proc IEEE Eng Med Biol Soc 6:4584-7. 2004
  3. ncbi request reprint Illusory percepts from auditory adaptation
    Lucas C Parra
    Biomedical Engineering Department, City College of New York, New York, NY 10031, USA
    J Acoust Soc Am 121:1632-41. 2007
  4. doi request reprint On the maximization of information flow between spiking neurons
    Lucas C Parra
    Biomedical Engineering Department, City College of New York, New York, NY 10033, USA
    Neural Comput 21:2991-3009. 2009
  5. doi request reprint Impaired cochlear function correlates with the presence of tinnitus and its estimated spectral profile
    Xiang Zhou
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    Hear Res 277:107-16. 2011
  6. pmc Automated MRI segmentation for individualized modeling of current flow in the human head
    Yu Huang
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY, USA, 10031
    J Neural Eng 10:066004. 2013
  7. pmc Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing
    Davide Reato
    Department of Biomedical Engineering, The City College of the City University of New York, New York 10031, USA
    J Neurosci 30:15067-79. 2010
  8. doi request reprint Validation of finite element model of transcranial electrical stimulation using scalp potentials: implications for clinical dose
    Abhishek Datta
    Neural Engineering Laboratory, Department of Biomedical Engineering, The City College of New York of City University of New York, NY 10031, USA
    J Neural Eng 10:036018. 2013
  9. ncbi request reprint Cortical origins of response time variability during rapid discrimination of visual objects
    Adam D Gerson
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Neuroimage 28:342-53. 2005
  10. pmc Targeted transcranial direct current stimulation for rehabilitation after stroke
    Jacek P Dmochowski
    City College of New York, New York, NY, USA
    Neuroimage 75:12-9. 2013

Collaborators

Detail Information

Publications44

  1. ncbi request reprint Recipes for the linear analysis of EEG
    Lucas C Parra
    Department of Biomedical Engineering, City College of New York, New York, NY 10031, USA
    Neuroimage 28:326-41. 2005
    ..The general approach is shown to be consistent with the underlying physics of EEG, which specifies a linear mixing model of the underlying neural and non-neural current sources...
  2. ncbi request reprint Model of the effect of extracellular fields on spike time coherence
    Lucas C Parra
    Department of Biomedical Engineering, City College of New York, NY 10031, USA
    Conf Proc IEEE Eng Med Biol Soc 6:4584-7. 2004
    ..We discuss the potential relevance of such a common input as an external "clock" signal in a spatio-temporal code...
  3. ncbi request reprint Illusory percepts from auditory adaptation
    Lucas C Parra
    Biomedical Engineering Department, City College of New York, New York, NY 10031, USA
    J Acoust Soc Am 121:1632-41. 2007
    ..Together with the modeling results, this supports the hypothesis that the phantom percept is a consequence of a central adaptation mechanism confronted with a degraded sensory apparatus...
  4. doi request reprint On the maximization of information flow between spiking neurons
    Lucas C Parra
    Biomedical Engineering Department, City College of New York, New York, NY 10033, USA
    Neural Comput 21:2991-3009. 2009
    ..When trained on correlated spike trains, the network learns to extract independent spike trains, thereby uncovering the underlying statistical structure and creating a more efficient representation of the incoming spike trains...
  5. doi request reprint Impaired cochlear function correlates with the presence of tinnitus and its estimated spectral profile
    Xiang Zhou
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    Hear Res 277:107-16. 2011
    ..83 ± 0.09, N = 19). Thus, cochlear function is strongly associated with the tinnitus percept and measures of cochlear function using DPOAEs provide additional diagnostic information over perceptual thresholds alone...
  6. pmc Automated MRI segmentation for individualized modeling of current flow in the human head
    Yu Huang
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY, USA, 10031
    J Neural Eng 10:066004. 2013
    ..Also, accurate placement of many high-density electrodes on an individual scalp is a tedious procedure. The goal was to develop fully automated techniques to reduce the manual effort in such a modeling process...
  7. pmc Low-intensity electrical stimulation affects network dynamics by modulating population rate and spike timing
    Davide Reato
    Department of Biomedical Engineering, The City College of the City University of New York, New York 10031, USA
    J Neurosci 30:15067-79. 2010
    ....
  8. doi request reprint Validation of finite element model of transcranial electrical stimulation using scalp potentials: implications for clinical dose
    Abhishek Datta
    Neural Engineering Laboratory, Department of Biomedical Engineering, The City College of New York of City University of New York, NY 10031, USA
    J Neural Eng 10:036018. 2013
    ..The goal was to characterize these scalp voltages for the purpose of validating subject-specific finite element method (FEM) models of current flow...
  9. ncbi request reprint Cortical origins of response time variability during rapid discrimination of visual objects
    Adam D Gerson
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    Neuroimage 28:342-53. 2005
    ..This activity is consistent with the hypothesis that cortical networks involved in generating the late positive complexes may be the origins of the observed response time variability in rapid discrimination of visual objects...
  10. pmc Targeted transcranial direct current stimulation for rehabilitation after stroke
    Jacek P Dmochowski
    City College of New York, New York, NY, USA
    Neuroimage 75:12-9. 2013
    ..These results demonstrate that MRI-based models of current flow yield maximal stimulation of target structures, and as such, may aid in reliably assessing the efficacy of tDCS in neuro-rehabilitation...
  11. pmc Cellular effects of acute direct current stimulation: somatic and synaptic terminal effects
    Asif Rahman
    Department of Biomedical Engineering, The City College of the City University of New York, Convent Avenue at 140th Street, Steinman Hall, 4th Floor, T 454, New York, NY 10031, USA
    J Physiol 591:2563-78. 2013
    ..We conclude that during acute DCS the cellular targets responsible for modulation of synaptic efficacy are concurrently somata and axon terminals, with the direction of cortical current flow determining the relative influence...
  12. doi request reprint Optimized multi-electrode stimulation increases focality and intensity at target
    Jacek P Dmochowski
    Department of Biomedical Engineering, City College of New York City University of New York, New York, NY 10031, USA
    J Neural Eng 8:046011. 2011
    ....
  13. ncbi request reprint Cortically coupled computer vision for rapid image search
    Adam D Gerson
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    IEEE Trans Neural Syst Rehabil Eng 14:174-9. 2006
    ..The approach leverages the highly robust and invariant object recognition capabilities of the human visual system, using single-trial EEG analysis to efficiently detect neural signatures correlated with the recognition event...
  14. doi request reprint Spectrum separation resolves partial-volume effect of MRSI as demonstrated on brain tumor scans
    Yuzhuo Su
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY 10031, USA
    NMR Biomed 21:1030-42. 2008
    ..These results show that the proposed spectral analysis method can improve the effectiveness of MRSI as a diagnostic tool...
  15. pmc Transcranial electrical stimulation accelerates human sleep homeostasis
    Davide Reato
    Department of Biomedical Engineering, The City College of the City University of New York, New York, New York, USA
    PLoS Comput Biol 9:e1002898. 2013
    ..Together these results suggest a mechanistic link between electrical stimulation and accelerated synaptic homeostasis in human sleep...
  16. pmc On the role of electric field orientation in optimal design of transcranial current stimulation
    Jacek P Dmochowski
    City College of New York, New York, NY 10031, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:6426-9. 2012
    ..This suggests that identifying the desired electric field orientation at the region of interest is a crucial step in the development of rational electrical stimulation paradigms...
  17. pmc The point spread function of the human head and its implications for transcranial current stimulation
    Jacek P Dmochowski
    Department of Biomedical Engineering, City College of New York, New York, NY 10031, USA
    Phys Med Biol 57:6459-77. 2012
    ..Finally, theoretically optimal montages for targeting an infinitesimal point in the brain are shown...
  18. pmc Single-trial analysis of neuroimaging data: inferring neural networks underlying perceptual decision-making in the human brain
    Paul Sajda
    Department of Biomedical Engineering, Columbia University, New York, NY 10027, USA
    IEEE Rev Biomed Eng 2:97-109. 2009
    ..We discuss how single-trial analysis reveals aspects of the underlying decision-making networks that are unobservable using traditional trial-averaging methods...
  19. doi request reprint Sensitization to masked tones following notched-noise correlates with estimates of cochlear function using distortion product otoacoustic emissions
    Xiang Zhou
    Department of Biomedical Engineering, The City College of the City University of New York, Steinman Hall, Room T 401, Convent Avenue, 140th Street, New York, New York 10031, USA
    J Acoust Soc Am 127:970-6. 2010
    ....
  20. pmc Clinician accessible tools for GUI computational models of transcranial electrical stimulation: BONSAI and SPHERES
    Dennis Q Truong
    Department of Biomedical Engineering, The City College of New York, City University of New York, New York, NY, USA Electronic address
    Brain Stimul 7:521-4. 2014
    ..These open-source tES modeling platforms are designed go be upgraded and enhanced. Trade-offs between open-access approaches that balance ease of access, speed, and flexibility are discussed...
  21. doi request reprint EEG precursors of detected and missed targets during free-viewing search
    Joao C Dias
    Department of Biomedical Engineering, City College of New York, City University of New York, New York, NY, USA
    J Vis 13:13. 2013
    ....
  22. pmc An automated method for high-definition transcranial direct current stimulation modeling
    Yu Huang
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY 10031, USA
    Conf Proc IEEE Eng Med Biol Soc 2012:5376-9. 2012
    ..We anticipate that such an automated processing will become an indispensable tool to individualize transcranial direct current stimulation (tDCS) therapy...
  23. doi request reprint Effects of high-frequency stimulation on epileptiform activity in vitro: ON/OFF control paradigm
    Yuzhuo Su
    Department of Biomedical Engineering, The City College of New York, City University of New York, New York, New York 10031, USA
    Epilepsia 49:1586-93. 2008
    ..To determine the effects of high-frequency electrical stimulation on electrographic seizure activity during and after stimulation (ON-effect and OFF-effect)...
  24. pmc Animal models of transcranial direct current stimulation: Methods and mechanisms
    Mark P Jackson
    Department of Biomedical Engineering, The City College of the City University of New York, NY, USA
    Clin Neurophysiol 127:3425-3454. 2016
    ..Use of animal models of disease are summarized including pain, movement disorders, stroke, and epilepsy...
  25. doi request reprint Subject position affects EEG magnitudes
    Justin K Rice
    City College of the City University of New York, Room ST 403, 160 Convent Avenue, New York, NY, 10031, USA
    Neuroimage 64:476-84. 2013
    ....
  26. pmc Vocal exploration is locally regulated during song learning
    Primoz Ravbar
    Departments of Biology and Biomedical Engineering, City College of New York, City University of New York, New York, New York 10031, USA
    J Neurosci 32:3422-32. 2012
    ..We hypothesize that either AFP adjusts the gain of vocal exploration in fine timescales or that the sensitivity of RA premotor neurons to AFP/HVC inputs varies across song elements...
  27. ncbi request reprint Spike timing amplifies the effect of electric fields on neurons: implications for endogenous field effects
    Thomas Radman
    Department of Biomedical Engineering, City College of the City University of New York, New York, New York 10031, USA
    J Neurosci 27:3030-6. 2007
    ..g., gamma) in brain function and introduce a framework for considering the effects of environmental fields and design of low-intensity therapeutic neurostimulation technologies...
  28. doi request reprint Direct Current Stimulation Alters Neuronal Input/Output Function
    Belen Lafon
    Department of Biomedical Engineering, The City College of the City University of New York, New York, NY, USA Electronic address
    Brain Stimul . 2016
    ..Changes of the neuronal I/O function by DCS may underlie previous observations in animal models and human testing, yet have not been directly assessed...
  29. pmc Lasting modulation of in vitro oscillatory activity with weak direct current stimulation
    Davide Reato
    Department of Biomedical Engineering, The City College of the City University of New York, New York, New York
    J Neurophysiol 113:1334-41. 2015
    ..Future experimental studies using this novel in vitro preparation may be able to confirm or refute the proposed hypothesis. ..
  30. pmc Inter-Individual Variation during Transcranial Direct Current Stimulation and Normalization of Dose Using MRI-Derived Computational Models
    Abhishek Datta
    Neural Engineering Laboratory, Department of Biomedical Engineering, The City College of City University of New York New York, NY, USA Soterix Medical New York, NY, USA
    Front Psychiatry 3:91. 2012
    ..The current flow profile across all subjects and montages was influenced by details in cortical gyri/sulci. Conclusion: This data suggests that subject specific modeling can facilitate consistent and more efficacious tDCS...
  31. pmc Correlated components of ongoing EEG point to emotionally laden attention - a possible marker of engagement?
    Jacek P Dmochowski
    Department of Biomedical Engineering, City College of NewYork NewYork, NY, USA
    Front Hum Neurosci 6:112. 2012
    ....
  32. ncbi request reprint Smooth bilinear classification of EEG
    Mads Dyrholm
    City Coll, City Univ of New York, NY 10031, USA
    Conf Proc IEEE Eng Med Biol Soc 1:4249-52. 2006
    ..Investigation of the trained classifier encourages us to belief that the method can also be useful as a tool to interpret the activity in the data at hand with respect to experimental events...
  33. doi request reprint The New York Head-A precise standardized volume conductor model for EEG source localization and tES targeting
    Yu Huang
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY 10031, USA
    Neuroimage 140:150-62. 2016
    ..We release all model data online at neuralengr.com/nyhead/ to facilitate broad adoption. ..
  34. pmc Temporal regularity increases with repertoire complexity in the Australian pied butcherbird's song
    Eathan Janney
    Department of Psychology, Hunter College, CUNY, New York, NY, USA
    R Soc Open Sci 3:160357. 2016
    ..We discuss alternative musical, mechanistic and ecological explanations to this effect...
  35. pmc Direct Current Stimulation Modulates LTP and LTD: Activity Dependence and Dendritic Effects
    Greg Kronberg
    Department of Biomedical Engineering, The City College of New York, New York, NY 10031, USA Electronic address
    Brain Stimul 10:51-58. 2017
    ..These learning effects are thought to be mediated by altered synaptic plasticity. However, the effects of DCS during the induction of endogenous synaptic plasticity remain largely unexplored...
  36. pmc The Effects of Compensatory Auditory Stimulation and High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Tinnitus Perception - A Randomized Pilot Study
    Simon Henin
    Department of Biomedical Engineering, City College of New York, 160 Convent Avenue, New York, New York 10027, United States of America
    PLoS ONE 11:e0166208. 2016
    ..Tinnitus correlates with elevated hearing thresholds and reduced cochlear compression. We hypothesized that reduced peripheral input leads to elevated neuronal gain resulting in the perception of a phantom sound...
  37. pmc Fully automated whole-head segmentation with improved smoothness and continuity, with theory reviewed
    Yu Huang
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY, USA
    PLoS ONE 10:e0125477. 2015
    ..In addition, a review on the MRI segmentation using atlas and the MRF over the last 20 years is also provided, with the general mathematical framework clearly derived. ..
  38. pmc Audience preferences are predicted by temporal reliability of neural processing
    Jacek P Dmochowski
    1 Department of Biomedical Engineering, City College of New York, 160 Convent Avenue, New York, New York 10027, USA 2 Present address Department of Psychology, Stanford University, 450 Serra Mall, Stanford, California 94305, USA
    Nat Commun 5:4567. 2014
    ..Our findings suggest that stimuli which we judge favourably may be those to which our brains respond in a stereotypical manner shared by our peers. ..
  39. doi request reprint Simulating pad-electrodes with high-definition arrays in transcranial electric stimulation
    René Kempe
    Department of Biomedical Engineering, City College of the City University of New York, New York, NY 10031, USA Department of Biomedical Engineering, Hamburg University of Applied Sciences, Hamburg, Germany
    J Neural Eng 11:026003. 2014
    ..We provide an efficient tool to estimate current distributions for arbitrary pad configurations while obviating the need for complex simulation software...
  40. pmc Computational model of neuron-astrocyte interactions during focal seizure generation
    Davide Reato
    Department of Biomedical Engineering, The City College of the City University of New York New York, NY, USA
    Front Comput Neurosci 6:81. 2012
    ..Our model can be used to obtain mechanistic insights into the distinct contributions of the different signaling pathways to the generation and propagation of focal IDs...
  41. ncbi request reprint Nonnegative matrix factorization for rapid recovery of constituent spectra in magnetic resonance chemical shift imaging of the brain
    Paul Sajda
    Laboratory of Intelligent Imaging and Neural Computing, Department of Biomedical Engineering, Columbia University, 351 Engineering Terrace Building, Mail Code 8904, 1210 Amsterdam Ave, New York, NY 10027, USA
    IEEE Trans Med Imaging 23:1453-65. 2004
    ..We demonstrate the hierarchical procedure on 1H brain data and conclude that the computational efficiency of the algorithm makes it well-suited for use in diagnostic work-up...
  42. pmc The development of stimulus-specific auditory responses requires song exposure in male but not female zebra finches
    Kristen K Maul
    Department of Biology, The City College of New York, City University of New York, New York, USA
    Dev Neurobiol 70:28-40. 2010
    ..We suggest that early auditory experience with songs may be required to tune perception toward conspecific songs in males, whereas in females song selectivity develops even without prior exposure to song...
  43. ncbi request reprint Response error correction--a demonstration of improved human-machine performance using real-time EEG monitoring
    Lucas C Parra
    Sarnoff Corporation, Princeton, NJ 08540, USA
    IEEE Trans Neural Syst Rehabil Eng 11:173-7. 2003
    ..We are currently investigating the generalization of the overall approach to other tasks and stimulus paradigms...
  44. ncbi request reprint Varying complexity in tree-structured image distribution models
    Clay Spence
    Sarnoff Corporation, Princeton, NJ 08540, USA
    IEEE Trans Image Process 15:319-30. 2006
    ..In all cases, we compare with the HMT...