Genomes and Genes
Brian M Varisco
Affiliation: Cincinnati Children's Hospital Medical Center
- The pharmacology of acute lung injury in sepsisBrian Michael Varisco
Division of Critical Care, Cincinnati Children s Hospital Medical Center, MLC 2005, Cincinnati, OH 45229 3039, USA
Adv Pharmacol Sci 2011:254619. 2011..In this paper, we discuss the epidemiology and pathophysiology of ALI, commonly employed pharmacologic and nonpharmacologic treatments, and innovative therapeutic modalities that will likely be the focus of future trials...
- JNK suppresses pulmonary fibroblast elastogenesis during alveolar developmentSheng Liu
Cincinnati Children s Hospital Research Foundation, Cincinnati, OH, USA
Respir Res 15:34. 2014..JNK suppress elastin synthesis in the aorta and is important in a host of developmental processes. We sought to determine whether JNK suppresses pulmonary fibroblast elastogenesis during lung development...
- Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lungBrian M Varisco
Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229, USA
Am J Respir Cell Mol Biol 46:765-72. 2012..Thy-1 is important in the regulation of lipofibroblast differentiation in the developing lung...
- Stretch regulates expression and binding of chymotrypsin-like elastase 1 in the postnatal lungRashika Joshi
Division of Critical Care Medicine, Division of Developmental Biology, and Division of Pulmonary Biology, Department of Clinical Engineering, and Biomedical Research Internship for Minority Students Program, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA and Ohio State University College of Veterinary Medicine, Columbus, Ohio, USA
FASEB J 30:590-600. 2016..Joshi, R., Liu, S., Brown, M. D., Young, S. M., Batie, M., Kofron, J. M., Xu, Y., Weaver, T. E., Apsley, K., Varisco, B. M. Stretch regulates expression and binding of chymotrypsin-like elastase 1 in the postnatal lung. ..
- Wntless is required for peripheral lung differentiation and pulmonary vascular developmentBridget Cornett
The Perinatal Institute Division of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Cincinnati Children s Hospital Medical Center Research Foundation, Cincinnati, OH 45229, USA
Dev Biol 379:38-52. 2013..These studies provide a new framework for understanding the molecular mechanisms underlying normal pulmonary vasculature formation and the dysmorphic pulmonary vasculature development associated with congenital lung disease...