Satish K Madala

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis
    Satish K Madala
    1 Department of Pediatrics, Divisions of Pulmonary Medicine and
    Am J Respir Cell Mol Biol 50:777-86. 2014
  2. pmc Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati, OH, USA
    Respir Res 13:51. 2012
  3. pmc p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Physiol Lung Cell Mol Physiol 310:L175-86. 2016
  4. pmc Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Respir Cell Mol Biol 55:792-803. 2016
  5. pmc MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
    Satish K Madala
    Department of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Respir Cell Mol Biol 46:380-8. 2012
  6. pmc Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 9:e86536. 2014
  7. pmc IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function
    Brijendra Singh
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 11:e0161877. 2016
  8. pmc Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
    Vishwaraj Sontake
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 Department of Biochemistry, National Institute of Nutrition, Hyderabad 500007, India
    J Immunol 195:3978-91. 2015
  9. pmc Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pulm Med 2011:653524. 2011

Collaborators

  • George Thomas
  • Machiko Ikegami
  • Brijendra Singh
  • Mario Medvedovic
  • Vishwaraj Sontake
  • Stacey R Dillon
  • Kumar S Shanmukhappa
  • Gurjit H Khurana
  • Ramakrishna Edukulla
  • Anil G Jegga
  • William D Hardie
  • Geereddy B Reddy
  • Eric S White
  • Betsy A DiPasquale
  • Shiva K Shanmukhappa

Detail Information

Publications9

  1. pmc Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis
    Satish K Madala
    1 Department of Pediatrics, Divisions of Pulmonary Medicine and
    Am J Respir Cell Mol Biol 50:777-86. 2014
    ..In summary, fibrocytes are increased in the progressive, fibrotic lesions of TGF-α-transgenic mice and activate resident fibroblasts to cause severe lung disease. ..
  2. pmc Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati, OH, USA
    Respir Res 13:51. 2012
    ..However, the direct role of Fizz1 produced in the pulmonary epithelium has not been determined...
  3. pmc p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Physiol Lung Cell Mol Physiol 310:L175-86. 2016
    ..Together these studies demonstrate targeting the S6K pathway selectively modifies the progression of pulmonary fibrosis in the subpleural compartment of the lung. ..
  4. pmc Unique and Redundant Functions of p70 Ribosomal S6 Kinase Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Respir Cell Mol Biol 55:792-803. 2016
    ....
  5. pmc MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
    Satish K Madala
    Department of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Respir Cell Mol Biol 46:380-8. 2012
    ..These findings demonstrate that MEK inhibition prevents progression of established fibrosis in the TGF-α model, and provides proof of concept of targeting the MEK pathway in fibrotic lung disease...
  6. pmc Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 9:e86536. 2014
    ....
  7. pmc IL-31-Driven Skin Remodeling Involves Epidermal Cell Proliferation and Thickening That Lead to Impaired Skin-Barrier Function
    Brijendra Singh
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 11:e0161877. 2016
    ..In summary, our findings demonstrate an important role for IL-31 signaling in epidermal cell proliferation and thickening that together may lead to impaired skin-barrier function in pathological remodeling of the skin. ..
  8. pmc Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
    Vishwaraj Sontake
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 Department of Biochemistry, National Institute of Nutrition, Hyderabad 500007, India
    J Immunol 195:3978-91. 2015
    ..Thus, the results of this study demonstrate a novel association between fibrocyte-driven WT1(+) cell accumulation and severe fibrotic lung disease. ..
  9. pmc Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pulm Med 2011:653524. 2011
    ..These findings indicate that novel therapeutics will be required to treat individuals with SP-C deficient ILD/IPF...