Satish K Madala

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis
    Satish K Madala
    1 Department of Pediatrics, Divisions of Pulmonary Medicine and
    Am J Respir Cell Mol Biol 50:777-86. 2014
  2. pmc Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati, OH, USA
    Respir Res 13:51. 2012
  3. pmc p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Physiol Lung Cell Mol Physiol 310:L175-86. 2016
  4. pmc MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
    Satish K Madala
    Department of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Respir Cell Mol Biol 46:380-8. 2012
  5. pmc Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 9:e86536. 2014
  6. pmc Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
    Vishwaraj Sontake
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 Department of Biochemistry, National Institute of Nutrition, Hyderabad 500007, India
    J Immunol 195:3978-91. 2015
  7. pmc Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pulm Med 2011:653524. 2011

Collaborators

  • George Thomas
  • Machiko Ikegami
  • Vishwaraj Sontake
  • Eric S White
  • Mario Medvedovic
  • Betsy A DiPasquale
  • William D Hardie
  • Geereddy B Reddy
  • Shiva K Shanmukhappa

Detail Information

Publications7

  1. pmc Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis
    Satish K Madala
    1 Department of Pediatrics, Divisions of Pulmonary Medicine and
    Am J Respir Cell Mol Biol 50:777-86. 2014
    ..In summary, fibrocytes are increased in the progressive, fibrotic lesions of TGF-α-transgenic mice and activate resident fibroblasts to cause severe lung disease. ..
  2. pmc Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati, OH, USA
    Respir Res 13:51. 2012
    ..However, the direct role of Fizz1 produced in the pulmonary epithelium has not been determined...
  3. pmc p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Am J Physiol Lung Cell Mol Physiol 310:L175-86. 2016
    ..Together these studies demonstrate targeting the S6K pathway selectively modifies the progression of pulmonary fibrosis in the subpleural compartment of the lung. ..
  4. pmc MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation
    Satish K Madala
    Department of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Am J Respir Cell Mol Biol 46:380-8. 2012
    ..These findings demonstrate that MEK inhibition prevents progression of established fibrosis in the TGF-α model, and provides proof of concept of targeting the MEK pathway in fibrotic lung disease...
  5. pmc Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, United States of America
    PLoS ONE 9:e86536. 2014
    ....
  6. pmc Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease
    Vishwaraj Sontake
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229 Department of Biochemistry, National Institute of Nutrition, Hyderabad 500007, India
    J Immunol 195:3978-91. 2015
    ..Thus, the results of this study demonstrate a novel association between fibrocyte-driven WT1(+) cell accumulation and severe fibrotic lung disease. ..
  7. pmc Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice
    Satish K Madala
    Division of Pulmonary Medicine, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Pulm Med 2011:653524. 2011
    ..These findings indicate that novel therapeutics will be required to treat individuals with SP-C deficient ILD/IPF...