Trent Hummel

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. doi request reprint A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas
    Trent R Hummel
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave MLC 7051, Cincinnati, OH, 45229, USA
    J Neurooncol 127:53-61. 2016
  2. pmc A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study
    Trent R Hummel
    Division of Oncology, Cincinnati Children s Hospital Medical Center, Cancer and Blood Diseases Institute, Cincinnati, Ohio 45229, USA
    Pediatr Blood Cancer 60:1452-7. 2013
  3. doi request reprint Pharmacotherapeutic management of pediatric gliomas : current and upcoming strategies
    Trent R Hummel
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Paediatr Drugs 15:29-42. 2013
  4. doi request reprint Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review
    Trent R Hummel
    Cancer and Blood Diseases Institute, Division of Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati OH 45229 3039, USA
    J Pediatr Hematol Oncol 34:e232-6. 2012
  5. doi request reprint Response of NF1-related plexiform neurofibroma to high-dose carboplatin
    Trent Hummel
    Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Pediatr Blood Cancer 56:488-90. 2011
  6. pmc Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
    Lindsey M Hoffman
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Acta Neuropathol Commun 4:13. 2016
  7. pmc Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
    Lindsey M Hoffman
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA
    Acta Neuropathol Commun 4:1. 2016
  8. doi request reprint Patterns of progression in pediatric patients with high-grade glioma or diffuse intrinsic pontine glioma treated with Bevacizumab-based therapy at diagnosis
    Ralph Salloum
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA
    J Neurooncol 121:591-8. 2015
  9. ncbi request reprint Response of NF1-related plexiform neurofibroma to High-Dose Carboplatin
    Trent Hummel
    Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Pediatr Blood Cancer 56:488-90. 2011

Collaborators

Detail Information

Publications9

  1. doi request reprint A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas
    Trent R Hummel
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave MLC 7051, Cincinnati, OH, 45229, USA
    J Neurooncol 127:53-61. 2016
    ..3K27M (n = 2 DIPG) or G34R (n = 1 HGG) mutations. QOL scores improved over the course of therapy. A bevacizumab-based regimen is feasible and tolerable in newly diagnosed children and young adults with HGG and DIPG. ..
  2. pmc A pediatric phase 1 trial of vorinostat and temozolomide in relapsed or refractory primary brain or spinal cord tumors: a Children's Oncology Group phase 1 consortium study
    Trent R Hummel
    Division of Oncology, Cincinnati Children s Hospital Medical Center, Cancer and Blood Diseases Institute, Cincinnati, Ohio 45229, USA
    Pediatr Blood Cancer 60:1452-7. 2013
    ....
  3. doi request reprint Pharmacotherapeutic management of pediatric gliomas : current and upcoming strategies
    Trent R Hummel
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH 45229, USA
    Paediatr Drugs 15:29-42. 2013
    ..Further research is required to understand the biology of pediatric gliomas as well as the use of molecularly targeted agents, especially in patients with surgically unresectable tumors...
  4. doi request reprint Clinical heterogeneity of desmoplastic infantile ganglioglioma: a case series and literature review
    Trent R Hummel
    Cancer and Blood Diseases Institute, Division of Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati OH 45229 3039, USA
    J Pediatr Hematol Oncol 34:e232-6. 2012
    ..Such adverse outcomes, combined with the recognition that DIG represents a heterogeneous disease, underscore the need for an expanded biological and molecular investigation...
  5. doi request reprint Response of NF1-related plexiform neurofibroma to high-dose carboplatin
    Trent Hummel
    Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Pediatr Blood Cancer 56:488-90. 2011
    ..Here, we present a case in which we describe the use of high-dose carboplatin to treat the patient's testicular seminoma which resulted in the decrease in size of a PN in a patient with NF1...
  6. pmc Erratum: Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
    Lindsey M Hoffman
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Acta Neuropathol Commun 4:13. 2016
    ....
  7. pmc Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics
    Lindsey M Hoffman
    Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA
    Acta Neuropathol Commun 4:1. 2016
    ..Validation was performed using Sanger sequencing, Droplet Digital polymerase-chain reaction, immunohistochemistry, and fluorescent in-situ hybridization...
  8. doi request reprint Patterns of progression in pediatric patients with high-grade glioma or diffuse intrinsic pontine glioma treated with Bevacizumab-based therapy at diagnosis
    Ralph Salloum
    Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA
    J Neurooncol 121:591-8. 2015
    ..Based on these data, we postulate that BVZ may lead to a higher incidence of distant and diffuse disease in newly-diagnosed children with HGG or DIPG who received BVZ-based therapy...
  9. ncbi request reprint Response of NF1-related plexiform neurofibroma to High-Dose Carboplatin
    Trent Hummel
    Division of Hematology Oncology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio
    Pediatr Blood Cancer 56:488-90. 2011
    ..Pediatr Blood Cancer 2011;56:488-490. © 2010 Wiley-Liss, Inc...