Vidya Chidambaran

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. pmc Propofol: a review of its role in pediatric anesthesia and sedation
    Vidya Chidambaran
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2001, Cincinnati, OH, 45229, USA
    CNS Drugs 29:543-63. 2015
  2. doi request reprint Pediatric acute and surgical pain management: recent advances and future perspectives
    Vidya Chidambaran
    Departments of Anesthesia and Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Int Anesthesiol Clin 50:66-82. 2012
  3. ncbi request reprint Pharmacogenetics and anesthetic drugs
    Vidya Chidambaran
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Curr Clin Pharmacol 7:78-101. 2012
  4. pmc ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children
    Raja Venkatasubramanian
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center 3333 Burnet Avenue, MLC 2001, Cincinnati, OH 45229, USA
    Pharmacogenomics 15:1297-309. 2014
  5. pmc OCT1 genetic variants influence the pharmacokinetics of morphine in children
    Tsuyoshi Fukuda
    Division of Clinical Pharmacology, Cincinnati Children s Hospital Medical Center, OH, USA
    Pharmacogenomics 14:1141-51. 2013
  6. doi request reprint Morphine clearance in children: does race or genetics matter?
    Senthilkumar Sadhasivam
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Opioid Manag 8:217-26. 2012
  7. pmc Genetics of pain perception, COMT and postoperative pain management in children
    Senthilkumar Sadhasivam
    Clinical Anaesthesia and Paediatrics, Acute and Perioperative Pain Service, Department of Anaesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2001, Cincinnati, OH 45229, USA
    Pharmacogenomics 15:277-84. 2014
  8. ncbi request reprint Fatty acid amide hydrolase-morphine interaction influences ventilatory response to hypercapnia and postoperative opioid outcomes in children
    Vidya Chidambaran
    Department of Anesthesia, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA
    Pharmacogenomics . 2016
  9. doi request reprint Opioid-related adverse effects in children undergoing surgery: unequal burden on younger girls with higher doses of opioids
    Senthilkumar Sadhasivam
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, 45040, USA
    Pain Med 16:985-97. 2015
  10. pmc Population pharmacokinetic-pharmacodynamic modeling and dosing simulation of propofol maintenance anesthesia in severely obese adolescents
    Vidya Chidambaran
    Division of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Paediatr Anaesth 25:911-23. 2015

Collaborators

Detail Information

Publications16

  1. pmc Propofol: a review of its role in pediatric anesthesia and sedation
    Vidya Chidambaran
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2001, Cincinnati, OH, 45229, USA
    CNS Drugs 29:543-63. 2015
    ....
  2. doi request reprint Pediatric acute and surgical pain management: recent advances and future perspectives
    Vidya Chidambaran
    Departments of Anesthesia and Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Int Anesthesiol Clin 50:66-82. 2012
    ..Ongoing research provides hope that future integration of pharmacogenetics, metabolomics, and proteomics in clinical decision and analgesic selection/dosing processes will maximize analgesia and minimize adverse effects...
  3. ncbi request reprint Pharmacogenetics and anesthetic drugs
    Vidya Chidambaran
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229 3039, USA
    Curr Clin Pharmacol 7:78-101. 2012
    ....
  4. pmc ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children
    Raja Venkatasubramanian
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center 3333 Burnet Avenue, MLC 2001, Cincinnati, OH 45229, USA
    Pharmacogenomics 15:1297-309. 2014
    ..Large interindividual variability in morphine pharmacokinetics could contribute to variability in morphine analgesia and adverse events...
  5. pmc OCT1 genetic variants influence the pharmacokinetics of morphine in children
    Tsuyoshi Fukuda
    Division of Clinical Pharmacology, Cincinnati Children s Hospital Medical Center, OH, USA
    Pharmacogenomics 14:1141-51. 2013
    ..To study variations in intravenous morphine pharmacokinetics in children, we examined the influence of genetic polymorphisms in OCT1...
  6. doi request reprint Morphine clearance in children: does race or genetics matter?
    Senthilkumar Sadhasivam
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio, USA
    J Opioid Manag 8:217-26. 2012
    ....
  7. pmc Genetics of pain perception, COMT and postoperative pain management in children
    Senthilkumar Sadhasivam
    Clinical Anaesthesia and Paediatrics, Acute and Perioperative Pain Service, Department of Anaesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2001, Cincinnati, OH 45229, USA
    Pharmacogenomics 15:277-84. 2014
    ..Effective perioperative analgesia is lacking for children owing to interindividual variations and underdosing of opioids caused by fear of adverse effects. We investigated the role of COMT SNPs on postoperative pain management in children...
  8. ncbi request reprint Fatty acid amide hydrolase-morphine interaction influences ventilatory response to hypercapnia and postoperative opioid outcomes in children
    Vidya Chidambaran
    Department of Anesthesia, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA
    Pharmacogenomics . 2016
    ..Fatty acid amide hydrolase (FAAH) degrades anandamide, an endogenous cannabinoid. We hypothesized that FAAH variants will predict risk of morphine-related adverse outcomes due to opioid-endocannabinoid interactions...
  9. doi request reprint Opioid-related adverse effects in children undergoing surgery: unequal burden on younger girls with higher doses of opioids
    Senthilkumar Sadhasivam
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio, 45040, USA
    Pain Med 16:985-97. 2015
    ..The effects of the child's sex on opioid response have not been well studied. The aim of this study is to determine the effects of sex on opioid-related adverse effects in children undergoing tonsillectomy...
  10. pmc Population pharmacokinetic-pharmacodynamic modeling and dosing simulation of propofol maintenance anesthesia in severely obese adolescents
    Vidya Chidambaran
    Division of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Paediatr Anaesth 25:911-23. 2015
    ..This study was aimed at characterizing pharmacokinetics (PK) and pharmacodynamics (PD) of propofol in SO adolescents, using bispectral index (BIS), and toward developing PK/PD model-based dosing guidelines...
  11. pmc Genetic risk signatures of opioid-induced respiratory depression following pediatric tonsillectomy
    Jacek Biesiada
    Division of Biomedical Informatics, Department of Pediatrics, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Pharmacogenomics 15:1749-1762. 2014
    ..Original submitted 9 July 2014; Revision submitted 19 September 2014...
  12. doi request reprint Pharmacogenomics of opioids and perioperative pain management
    Senthilkumar Sadhasivam
    Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, MLC 2001, Cincinnati, OH 45229, USA
    Pharmacogenomics 13:1719-40. 2012
    ....
  13. doi request reprint Risk predictors of opioid-induced critical respiratory events in children: naloxone use as a quality measure of opioid safety
    Vidya Chidambaran
    Department of Anesthesia and Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA
    Pain Med 15:2139-49. 2014
    ..Naloxone administration triggered by OIRD has been used to monitor safety of opioid therapy in adults. We used this trigger as a quality measure of opioid safety in hospitalized children to identify risk predictors of OIRD...
  14. doi request reprint Anesthesia- and opioids-related malpractice claims following tonsillectomy in USA: LexisNexis claims database 1984-2012
    Rajeev Subramanyam
    Department of Anesthesia, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Paediatr Anaesth 24:412-20. 2014
    ..We have reviewed malpractice claims involving fatal and nonfatal injuries following tonsillectomy with an emphasis on anesthesia- and opioid-related claims and their characteristics...
  15. pmc Race and unequal burden of perioperative pain and opioid related adverse effects in children
    Senthilkumar Sadhasivam
    Division of Human Genetics, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Pediatrics 129:832-8. 2012
    ..Adult studies suggest pain management is influenced by patient's race. The objective of this study is to evaluate the influence of race on perioperative pain treatment in children...