Sheila M Bell

Summary

Affiliation: Cincinnati Children's Hospital Medical Center
Country: USA

Publications

  1. ncbi request reprint Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly
    Sheila M Bell
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Dev Dyn 233:313-25. 2005
  2. pmc Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium
    Sheila M Bell
    Perinatal Institute of Cincinnati Children s Hospital Medical Center, Division of Neonatology Perinatal Pulmonary Biology, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 358:79-90. 2011
  3. ncbi request reprint The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons
    Ronald R Waclaw
    Division of Developmental Biology, Department of Pediatrics, Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Neuron 49:503-16. 2006
  4. pmc Kruppel-like factor 5 is required for perinatal lung morphogenesis and function
    Huajing Wan
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Development 135:2563-72. 2008
  5. doi request reprint R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
    Sheila M Bell
    Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Development 135:1049-58. 2008
  6. ncbi request reprint Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling
    William J Scott
    Division of Developmental Biology and The Department of Pediatrics, Children s Hospital Medical Center and the University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Reprod Toxicol 19:479-85. 2005
  7. pmc Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium
    Sheila M Bell
    Perinatal Institute, Divisions of Neonatology Perinatal Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 375:128-39. 2013
  8. pmc Sp8 is crucial for limb outgrowth and neuropore closure
    Sheila M Bell
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 100:12195-200. 2003
  9. doi request reprint Microarray analysis of murine limb bud ectoderm and mesoderm after exposure to cadmium or acetazolamide
    Claire M Schreiner
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Birth Defects Res A Clin Mol Teratol 85:588-98. 2009
  10. pmc Forkhead Box m1 transcription factor is required for perinatal lung function
    Tanya V Kalin
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 105:19330-5. 2008

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Shh signaling in limb bud ectoderm: potential role in teratogen-induced postaxial ectrodactyly
    Sheila M Bell
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
    Dev Dyn 233:313-25. 2005
    ..We postulate that teratogen exposure alters the ability of Shh to signal to the ectoderm and present microarray and reverse transcriptase-polymerase chain reaction data, indicating that Shh signaling could occur in the limb bud ectoderm...
  2. pmc Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium
    Sheila M Bell
    Perinatal Institute of Cincinnati Children s Hospital Medical Center, Division of Neonatology Perinatal Pulmonary Biology, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 358:79-90. 2011
    ..Deletion of Klf5 from the developing bladder urothelium blocked epithelial cell differentiation, impaired bladder morphogenesis and function causing hydroureter and hydronephrosis at birth...
  3. ncbi request reprint The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons
    Ronald R Waclaw
    Division of Developmental Biology, Department of Pediatrics, Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
    Neuron 49:503-16. 2006
    ....
  4. pmc Kruppel-like factor 5 is required for perinatal lung morphogenesis and function
    Huajing Wan
    Division of Pulmonary Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
    Development 135:2563-72. 2008
    ..KLF5 regulates genes controlling paracrine interactions during lung morphogenesis, as well as those regulating the maturation of the respiratory epithelium that is required for lung function after birth...
  5. doi request reprint R-spondin 2 is required for normal laryngeal-tracheal, lung and limb morphogenesis
    Sheila M Bell
    Section of Neonatology, Perinatal and Pulmonary Biology, Cincinnati Children s Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA
    Development 135:1049-58. 2008
    ..Interbreeding the Rspo2(Tg) and Lrp6(-) alleles resulted in more severe defects consisting of marked lung hypoplasia and absence of tracheal-bronchial rings, laryngeal structures and all limb skeletal elements...
  6. ncbi request reprint Cadmium-induced postaxial forelimb ectrodactyly: association with altered sonic hedgehog signaling
    William J Scott
    Division of Developmental Biology and The Department of Pediatrics, Children s Hospital Medical Center and the University of Cincinnati, Cincinnati, OH 45229 3039, USA
    Reprod Toxicol 19:479-85. 2005
    ..Yet the expression of Shh and its translation are not affected by Cd(2+) exposure. We propose that teratogen exposure affects the processing of Shh in the cells in which it is made...
  7. pmc Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium
    Sheila M Bell
    Perinatal Institute, Divisions of Neonatology Perinatal Pulmonary Biology, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Dev Biol 375:128-39. 2013
    ..These studies indicate a novel requirement for KLF5 to initiate morphogenesis of the early endoderm into a compartmentalized intestinal epithelium comprised of villi and terminally differentiated cells...
  8. pmc Sp8 is crucial for limb outgrowth and neuropore closure
    Sheila M Bell
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 100:12195-200. 2003
    ..These observations indicate that Sp8 functions downstream of Wnt3, Fgf10, and Bmpr1a in the signaling cascade that mediates AER formation...
  9. doi request reprint Microarray analysis of murine limb bud ectoderm and mesoderm after exposure to cadmium or acetazolamide
    Claire M Schreiner
    Division of Developmental Biology, Cincinnati Children s Hospital Medical Center, and Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio 45229, USA
    Birth Defects Res A Clin Mol Teratol 85:588-98. 2009
    ..This malformation, postaxial, right-sided forelimb ectrodactyly, is thought to arise via an alteration of hedgehog signaling...
  10. pmc Forkhead Box m1 transcription factor is required for perinatal lung function
    Tanya V Kalin
    Division of Pulmonary Biology, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Proc Natl Acad Sci U S A 105:19330-5. 2008
    ..Foxm1 is critical for surfactant homeostasis and lung maturation before birth and is required for adaptation to air breathing...
  11. ncbi request reprint Type V collagen controls the initiation of collagen fibril assembly
    Richard J Wenstrup
    Division of Human Genetics, Cincinnati Children s Hospital Research Foundation, 3333 Burnet Ave, ML 4006, Cincinnati, OH 45229, USA
    J Biol Chem 279:53331-7. 2004
    ..In addition, this fibril collagen is important in the determination of fibril structure and matrix organization...
  12. ncbi request reprint Asymmetric limb malformations in a new transgene insertional mutant, footless
    Sheila M Bell
    Division of Developmental Biology, Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    Mech Dev 120:597-605. 2003
    ..However, dysmorphology of the apical ectodermal ridge was observed in the mutant limb buds...
  13. ncbi request reprint The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase
    Marian L Miller
    Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, 3223 Eden Avenue, Cincinnati, OH 45267 0056, USA
    Cell Tissue Res 309:369-80. 2002
    ....
  14. ncbi request reprint Replicated anterior zeugopod (raz): a polydactylous mouse mutant with lowered Shh signaling in the limb bud
    Ottheinz Krebs
    Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig Maximilian University, Munich, Germany
    Development 130:6037-47. 2003
    ..We propose that the double anterior zeugopod and symmetrical central polydactyly are due to an increased and uniform concentration of the Gli3 repressor form because of lowered Shh signaling...