Children's Mercy Hospital

Summary

Organization: Children's Mercy Hospital
Country: USA

Top Publications

  1. doi Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
    Angels Navarro
    Department of Pediatrics, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, USA
    Am J Physiol Lung Cell Mol Physiol 300:L32-42. 2011
  2. doi Angiomatoid fibrous histiocytoma with t(2;22)(q33;q12.2) and EWSR1 gene rearrangement
    Lei Shao
    Department of Pathology, Children s Mercy Hospitals and Clinics, School of Medicine, University of Missouri Kansas City, Kansas City, MO, USA
    Pediatr Dev Pathol 12:143-6. 2009
  3. doi Single-dose pharmacokinetics of oral and intravenous pantoprazole in children and adolescents
    Gregory L Kearns
    Division of Pediatric Pharmacology and Medical Toxicology, The Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    J Clin Pharmacol 48:1356-65. 2008
  4. doi The impact of home cleaning on quality of life for homes with asthmatic children
    Charles S Barnes
    The Department of Allergy, Asthma, and Immunology, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Allergy Asthma Proc 29:197-204. 2008
  5. doi Antral inflammatory cells, gastric emptying, and electrogastrography in pediatric functional dyspepsia
    Craig A Friesen
    Section of Gastroenterology, The Children s Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Dig Dis Sci 53:2634-40. 2008
  6. pmc Medical treatment of pediatric urolithiasis
    Uri S Alon
    Bone and Mineral Disorders Clinic, Children s Mercy Hospital and Clinics, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 24:2129-35. 2009
  7. ncbi Emerging cutaneous infections in the premature neonate
    Kimberly A Horii
    Section of Dermatology, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Adv Dermatol 23:177-95. 2007
  8. ncbi Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype
    A Gaedigk
    Section of Developmental Pharmacology and Experimental Therapeutics, Children s Mercy Hospital and Clinics, Kansas City, Missouri, USA
    Clin Pharmacol Ther 81:817-20. 2007
  9. ncbi Atypical fibroxanthoma and squamous cell carcinoma of the conjunctiva in xeroderma pigmentosum
    Lei Shao
    Department of Pathology, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Dev Pathol 10:149-52. 2007
  10. ncbi The future of emergency care of children: mind the gaps
    Jane F Knapp
    Office of Graduate Medical Education, Division of Emergency Medicine, Children s Mercy Hospital and Clinics, Kansas City, MO 64108, USA
    Ambul Pediatr 7:147-9. 2007

Detail Information

Publications62

  1. doi Polarized migration of lymphatic endothelial cells is critically dependent on podoplanin regulation of Cdc42
    Angels Navarro
    Department of Pediatrics, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, USA
    Am J Physiol Lung Cell Mol Physiol 300:L32-42. 2011
    ..Taken together, the results indicate that polarized migration of lymphatic endothelial cells in response to VEGF is mediated via a pathway of podoplanin regulation of small GTPase activities, in particular Cdc42...
  2. doi Angiomatoid fibrous histiocytoma with t(2;22)(q33;q12.2) and EWSR1 gene rearrangement
    Lei Shao
    Department of Pathology, Children s Mercy Hospitals and Clinics, School of Medicine, University of Missouri Kansas City, Kansas City, MO, USA
    Pediatr Dev Pathol 12:143-6. 2009
    ..We present a case of AFH in the inguinal region of a 12-year-old girl. The tumor showed characteristic histological features, t(2;22)(q33;q12.2), and EWSR gene rearrangement by fluorescence in situ hybridization...
  3. doi Single-dose pharmacokinetics of oral and intravenous pantoprazole in children and adolescents
    Gregory L Kearns
    Division of Pediatric Pharmacology and Medical Toxicology, The Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    J Clin Pharmacol 48:1356-65. 2008
    ..The pharmacokinetic profile of oral and intravenous pantoprazole was similar in children ages 2 to 16 years. The doses used here were safe and well tolerated in this population...
  4. doi The impact of home cleaning on quality of life for homes with asthmatic children
    Charles S Barnes
    The Department of Allergy, Asthma, and Immunology, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Allergy Asthma Proc 29:197-204. 2008
    ..Emphasis on cleaning and cleaning education combined with hypochlorite-based cleaning supplies resulted in significantly improved QOL for families with asthmatic children...
  5. doi Antral inflammatory cells, gastric emptying, and electrogastrography in pediatric functional dyspepsia
    Craig A Friesen
    Section of Gastroenterology, The Children s Mercy Hospital and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Dig Dis Sci 53:2634-40. 2008
    ....
  6. pmc Medical treatment of pediatric urolithiasis
    Uri S Alon
    Bone and Mineral Disorders Clinic, Children s Mercy Hospital and Clinics, University of Missouri at Kansas City, 64108, USA
    Pediatr Nephrol 24:2129-35. 2009
    ..This review discusses the current options of medical treatment of pediatric urolithiasis...
  7. ncbi Emerging cutaneous infections in the premature neonate
    Kimberly A Horii
    Section of Dermatology, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Adv Dermatol 23:177-95. 2007
    ..Fungal and bacterial infections should always be included in the differential diagnosis of unusual-appearing skin lesions in the premature neonate since prompt evaluation and aggressive therapy is paramount in this high-risk population...
  8. ncbi Identification and characterization of CYP2D6*56B, an allele associated with the poor metabolizer phenotype
    A Gaedigk
    Section of Developmental Pharmacology and Experimental Therapeutics, Children s Mercy Hospital and Clinics, Kansas City, Missouri, USA
    Clin Pharmacol Ther 81:817-20. 2007
    ..The rationale for this study was to resolve the discordance and to describe the novel non-functional allelic variant of CYP2D6 and its frequency in populations of different ethnic backgrounds...
  9. ncbi Atypical fibroxanthoma and squamous cell carcinoma of the conjunctiva in xeroderma pigmentosum
    Lei Shao
    Department of Pathology, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Dev Pathol 10:149-52. 2007
    ..We describe a unique case of a 6-year-old African American boy with XP who developed an atypical fibroxanthoma and 2 squamous cell carcinomas in the conjunctiva. The clinical and histopathologic findings of AFX are discussed...
  10. ncbi The future of emergency care of children: mind the gaps
    Jane F Knapp
    Office of Graduate Medical Education, Division of Emergency Medicine, Children s Mercy Hospital and Clinics, Kansas City, MO 64108, USA
    Ambul Pediatr 7:147-9. 2007
  11. pmc Chronic kidney disease in children: the global perspective
    Bradley A Warady
    Department of Pediatrics, Section of Nephrology, The Childrens Mercy Hospital, Kansas City, MO, USA
    Pediatr Nephrol 22:1999-2009. 2007
    ..Additional efforts to define the epidemiology of pediatric CKD worldwide are necessary if a better understanding of the full extent of the problem, areas for study, and the potential impact of intervention is desired...
  12. ncbi Neurologic complications in children hospitalized with influenza: characteristics, incidence, and risk factors
    Jason G Newland
    Division of Infectious Diseases, Children s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Pediatr 150:306-10. 2007
    ..To determine the characteristics, incidence, and risk factors for influenza-related neurologic complications (INC)...
  13. ncbi Child and provider restraints in ambulances: knowledge, opinions, and behaviors of emergency medical services providers
    Timothy D Johnson
    Division of Emergency Medicine, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Acad Emerg Med 13:886-92. 2006
    ..Information about emergency medical services (EMS) provider knowledge, opinions, and behaviors regarding occupant restraint is lacking...
  14. ncbi Sodium ferric gluconate complex maintenance therapy in children on hemodialysis
    Bradley A Warady
    The Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Nephrol 21:553-60. 2006
    ..0 mg/kg, not to exceed 125 mg, with subsequent adjustments made according to TSAT and/or serum ferritin levels...
  15. doi Neuroimaging-use trends in nonacute pediatric headache before and after clinical practice parameters
    William D Graf
    Sections of aNeurology, Children s Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA
    Pediatrics 122:e1001-5. 2008
    ..The objective of this study was to determine trends in diagnostic neuroimaging-use rates in nonacute pediatric headache before and after publication of clinical practice guidelines...
  16. doi Treatment strategies for methicillin-resistant Staphylococcus aureus infections in pediatrics
    Jason G Newland
    Department of Pediatrics, University of Missouri Kansas City, Kansas City, Missouri, USA
    Paediatr Drugs 10:367-78. 2008
    ..In other invasive MRSA infections, such as pneumonia and musculoskeletal infections, the empiric treatment of choice is clindamycin. Finally, newer agents and additional treatment options are discussed...
  17. doi Variations in psychological profile among children with recurrent abdominal pain
    Jennifer Verrill Schurman
    Section of Developmental and Behavioral Pediatrics, The Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    J Clin Psychol Med Settings 15:241-51. 2008
    ..Distinct psychological profiles appear to exist for children with RAP. Targeting treatments to these profiles may improve the effectiveness and efficiency with which health professionals address pediatric abdominal pain...
  18. doi Prognostic factors in pediatric acute myeloid leukemia
    Mohamed Radhi
    Children s Mercy Hospital, Kansas City, MO 64108, USA
    Curr Hematol Malig Rep 5:200-6. 2010
    ..This review provides a detailed analysis of most clinically relevant factors associated with disease outcome in childhood AML...
  19. doi Lifetime cardiovascular risk of childhood obesity
    Geetha Raghuveer
    Children s Mercy Hospital and Clinics, and The University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Am J Clin Nutr 91:1514S-1519S. 2010
    ..The effect of risk factor modification on the vasculature will continue to be a resource for the direction of evidence-based therapy in obese children...
  20. doi Clinical events after surgical splenectomy in children with sickle cell anemia
    Ram Kalpatthi
    Division of Pediatric Hematology and Oncology, The Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Pediatr Surg Int 26:495-500. 2010
    ..We seek to investigate the true prevalence of sepsis and other complications of splenectomy in this patient population...
  21. doi Initial laparoscopic appendectomy versus initial nonoperative management and interval appendectomy for perforated appendicitis with abscess: a prospective, randomized trial
    Shawn D St Peter
    Center for Prospective Clinical Trials, The Children s Mercy Hospital, Kansas City, MO, USA
    J Pediatr Surg 45:236-40. 2010
    ..Therefore, we conducted a randomized trial comparing these 2 management strategies...
  22. ncbi Defining the late implementation of extracorporeal membrane oxygenation (ECMO) by identifying increased mortality risk using specific physiologic cut-points in neonatal and pediatric respiratory patients
    Gary Grist
    Section of Cardiovascular Surgery, The Children s Mercy Hospitals and Clinics, Kansas City, Missouri 64108, USA
    J Extra Corpor Technol 41:213-9. 2009
    ..This study describes specific physiologic markers taken soon after ECMO initiation that correlate with mortality. These markers, if assessed earlier, may allow for a more timely ECMO implementation and higher survival...
  23. ncbi Innate immunity as a key element in host defense against methicillin resistant Staphylococcus aureus
    C J Harrison
    Children s Mercy Hospital and Clinics, University of Missouri at Kansas City, Kansas City, MO 64060, USA
    Minerva Pediatr 61:503-14. 2009
    ..The balance between these and similar innate immune responses and bacterial virulence factors likely determines whether MRSA colonization/exposure results in infection of skin or soft tissue...
  24. ncbi Noninvasive radial artery tonometry augmentation index and urinary albumin/creatinine levels in early adolescents with type 1 diabetes mellitus
    L Kurt Midyett
    Section of Endocrinology Diabetes, Children s Mercy Hospital and Clinics, Kansas City, MO, USA
    J Pediatr Endocrinol Metab 22:531-7. 2009
    ..Forty-five adolescents with DM1 and 42 controls between the ages of 12 and 14 years were recruited. Radial artery stiffness and urinary albumin/creatinine ratios of the adolescents with DM1 were not different from controls...
  25. ncbi Adrenocortical neoplasms in young children: age as a prognostic factor
    Atif Ali Ahmed
    Department of Pathology and Laboratory Medicine, Children s Mercy Hospitals, 2401 Gillham Road, Kansas City, MO 64108, USA
    Ann Clin Lab Sci 39:277-82. 2009
    ..Because of the discrepancy between pathology and clinical outcome, adrenocortical tumors in this age group should be classified as neoplasms of unknown malignant potential...
  26. pmc Refining the 22q11.2 deletion breakpoints in DiGeorge syndrome by aCGH
    D C Bittel
    Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO 64108, USA
    Cytogenet Genome Res 124:113-20. 2009
    ..2 deletion or DiGeorge syndrome...
  27. doi Personalized medicine: reality and reality checks
    J Steven Leeder
    Division of Clinical Pharmacology and MedicalToxicology, Children s Mercy Hospitals and Clinics, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Ann Pharmacother 43:963-6. 2009
    ..The reality is that personalized medicine is upon us; open discourse and periodic reality checks will be necessary as we confront it...
  28. doi Hematologic characterization and chromosomal localization of the novel dominantly inherited mouse hemolytic anemia, neonatal anemia (Nan)
    Robert A White
    Department of Pediatrics, Children s Mercy Hospitals and Clinics, Kansas City, MO 64108, USA
    Blood Cells Mol Dis 43:141-8. 2009
    ..The identification of the Nan gene will likely uncover a novel protein that contributes to the stability of the EMS and may identify a new mutation for HS...
  29. doi Pediatric organ donation: a national survey examining consent rates and characteristics of donor hospitals
    Patricia A Webster
    Critical Care Medicine Section, Children s Mercy Hospital, Kansas City, MO, USA
    Pediatr Crit Care Med 10:500-4. 2009
    ..To characterize the eligible pediatric donor pool in the United States by age, consent rate, location, and cause of donor loss...
  30. pmc Thoracoscopic decortication vs tube thoracostomy with fibrinolysis for empyema in children: a prospective, randomized trial
    Shawn D St Peter
    Center for Prospective Clinical Trials, Department of Pediatric Surgery, Children s Mercy Hospital, Kansas City, MO 64108, USA
    J Pediatr Surg 44:106-11; discussion 111. 2009
    ..Therefore, we conducted a prospective, randomized trial comparing VATS to fibrinolytic therapy in children with empyema...
  31. ncbi Recurrence of proteinuria following renal transplantation in congenital nephrotic syndrome of the Finnish type
    Tarak Srivastava
    Section of Nephrology, The Children s Mercy Hospital, 2401 Gillham Road, Kansas City, Missouri 64108, USA, and Department of Biochemistry, University of Oulu, Finland
    Pediatr Nephrol 21:711-8. 2006
    ..This is the first report of increased Palb activity in recurrence of proteinuria following transplantation in NPHS1. We speculate the role of increased Palb activity in the recurrence of proteinuria following transplantation in NPHS1...
  32. ncbi Nondiabetic consequences of obesity on kidney
    Tarak Srivastava
    Section of Pediatric Nephrology, Children s Mercy Hospitals and Clinics and University of Missouri, Kansas City, MO 64108, USA
    Pediatr Nephrol 21:463-70. 2006
    ..The purpose of this review is to highlight the nondiabetic consequences of obesity on kidney for the pediatric nephrology community as we begin to address the obesity epidemic in children...
  33. ncbi Diagnosing asthma in young children
    Jay M Portnoy
    Section of Allergy, Asthma, and Immunology, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    Curr Allergy Asthma Rep 2:447-52. 2002
    ..Routine use of clinically useful criteria for making the diagnosis, as outlined in this review, may help to simplify the process of making an early diagnosis of asthma...
  34. ncbi Prominent pruritic periumbilical papules: allergic contact dermatitis to nickel
    Vidya Sharma
    Section of Dermatology, Children s Mercy Hospital, Missouri 64108, USA
    Pediatr Dermatol 19:106-9. 2002
    ..We speculated that this was an ACD to nickel and performed patch tests in 9 (24%) of these patients. All 9 (100%) patients had positive patch test results for nickel, thus confirming the diagnosis...
  35. ncbi Effect of rapid diagnosis of influenza virus type a on the emergency department management of febrile infants and toddlers
    Vidya Sharma
    Department of Pediatrics, Children s Mercy Hospital, 2401 Gilham Rd, Kansas City, MO 64108, USA
    Arch Pediatr Adolesc Med 156:41-3. 2002
    ..To our knowledge, the effect on other diagnostic testing in an emergency department (ED) has not been examined...
  36. ncbi Nonenhanced limited CT in children suspected of having appendicitis: prospective comparison of attending and resident interpretations
    L H Lowe
    Department of Radiology, Children s Mercy Hospital and University of Missouri, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Radiology 221:755-9. 2001
    ..To prospectively compare resident and attending radiologic interpretations of nonenhanced limited computed tomographic (CT) scans obtained in children suspected of having appendicitis...
  37. ncbi Do hair care practices affect the acquisition of tinea capitis? A case-control study
    V Sharma
    Department of Pediatrics, Children s Mercy Hospital, 2401 Gilham Rd, Kansas City, MO 64108, USA
    Arch Pediatr Adolesc Med 155:818-21. 2001
    ..To determine the influences of hair-grooming practices and environmental factors as risk factors for the acquisition of tinea capitis (TC) in children...
  38. ncbi Immunotherapy for inhalant allergies. Guidelines for why, when, and how to use this treatment
    J M Portnoy
    Section of Allergy, Asthma, and Immunology, Children s Mercy Hospital, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Postgrad Med 109:89-90, 93-4, 99-100 passim. 2001
    ..In this article, Dr Portnoy discusses the role of immunotherapy in patients with symptoms triggered by airborne allergens...
  39. ncbi Allergenic materials in the house dust of allergy clinic patients
    C Barnes
    Section of Allergy Immunology, The Children s Mercy Hospital, Kansas City, MO 64108, USA
    Ann Allergy Asthma Immunol 86:517-23. 2001
    ..Comparisons are made between household allergen levels of children seen for asthma and children seen for other reasons...
  40. ncbi Inflammation and cystic fibrosis pulmonary disease
    M J Kennedy
    Division of Pharmacotherapy, School of Pharmacy, University of North Carolina at Chapel Hill, USA
    Pharmacotherapy 21:593-603. 2001
    ....
  41. ncbi Growth during and after a trial of growth hormone releasing hormone 1-29 in children with idiopathic short stature or growth hormone neurosecretory dysfunction
    I D Schwartz
    Section of Endocrinology Diabetes, The Children s Mercy Hospital, and The University of Missouri Kansas City School of Medicine, Missouri, USA
    J Pediatr Endocrinol Metab 13:645-50. 2000
    ..Despite prior reports to the contrary, GHND patients do not experience a sustained increased in growth rate upon discontinuation of GHRH...
  42. ncbi Prevention of premature birth: do pediatricians have a role?
    R T Hall
    Division of Human Development, Children s Mercy Hospital, Kansas City, Missouri 64108 4698, USA
    Pediatrics 105:1137-40. 2000
    ....
  43. ncbi Updates in wound management for the pediatrician
    J F Knapp
    Department of Pediatrics, University of Missouri Kansas City School of Medicine, USA
    Pediatr Clin North Am 46:1201-13. 1999
    ..Antibiotic prophylaxis is seldom needed. Human and animal bites raise special concerns in the assessment for primary repair and prophylactic antibiotic use...
  44. ncbi Autosomal dominant inheritance of multicystic dysplastic kidney
    T Srivastava
    Section of Pediatric Nephrology, Children s Mercy Hospital, Kansas City, MO 64108, USA
    Pediatr Nephrol 13:481-3. 1999
    ..The MCDK in the children continues to involute on follow-up urinary tract ultrasonography. The inheritance of MCDK appears to be autosomal dominant in this family...
  45. ncbi Bilateral nephrectomy reverses hypothyroidism in congenital nephrotic syndrome
    V Chadha
    Section of Pediatric Nephrology, The Children s Mercy Hospital, Kansas City, MO 64108, USA
    Pediatr Nephrol 13:209-11. 1999
    ..Abatement of massive proteinuria enables discontinuation of thyroid supplementation, and a transient rise in TSH in the early post-nephrectomy stage should be potentially expected...
  46. ncbi Developmental and pediatric pharmacogenomics
    J Steven Leeder
    Section of Developmental Pharmacology and Experimental Therapeutics, Division of Pediatric Pharmacology and Medical Toxicology, Children s Mercy Hospital and Clinics, Kansas City, MO, USA
    Pharmacogenomics 4:331-41. 2003
    ..Thus, there is considerable potential for large-scale pharmacogenomic technologies to impact the development and utilization of new therapeutic strategies in children...
  47. ncbi Vagal nerve stimulation in refractory epilepsy: the first 100 patients receiving vagal nerve stimulation at a pediatric epilepsy center
    Jerome V Murphy
    Neurology Section, Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Arch Pediatr Adolesc Med 157:560-4. 2003
    ..To determine the outcome of intermittent left vagal nerve stimulation on the first 100 consecutive patients treated at our pediatric epilepsy center...
  48. ncbi Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis
    Zhixing Li
    Renal Division, Department of Medicine, Brigham and Women s Hospital Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
    Biochem Biophys Res Commun 306:623-8. 2003
    ..Analysis of expression in in vitro cell culture models suggests that Debt91 is an immediate early gene up-regulated during growth factor-induced branching tubulogenesis...
  49. ncbi Use of aromatase inhibitors in children with short stature
    Joseph Cernich
    Section of Endocrinology, Department of Pediatrics, Children s Mercy Hospitals and Clinics and the University of Missouri Kansas City School of Medicine, USA
    Pediatr Endocrinol Rev 2:2-7. 2004
    ..Other studies have evaluated the effects on bone mineral density, lipid metabolism and adrenal function in children. This review summarizes the studies in the pediatric population and some of the metabolic effects in adults...
  50. ncbi CYP2D6*36 gene arrangements within the cyp2d6 locus: association of CYP2D6*36 with poor metabolizer status
    Andrea Gaedigk
    Section of Developmental Pharmacology and Experimental Therapeutics, Children s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA
    Drug Metab Dispos 34:563-9. 2006
    ..Given a combined frequency of between 0.5 and 3% in African Americans and Asians, genotyping for CYP2D6*36 should improve the accuracy of genotype-based phenotype prediction in these populations...
  51. ncbi Human immunodeficiency virus postexposure prophylaxis in child and adolescent victims of sexual assault
    Robert D Schremmer
    Division of Emergency Medical Services, Children s Mercy Hospitals and Clinics, Kansas City, MO 64108, USA
    Pediatr Emerg Care 21:502-6. 2005
    ....
  52. ncbi Laparoscopic patch repair of diaphragmatic hernias with Surgisis
    George W Holcomb
    Department of Surgery, Children s Mercy Hospital, Kansas City, MO 64108 4698, USA
    J Pediatr Surg 40:E1-5. 2005
    ..In most of the reports, prosthetic mesh has not been used, and when used, it has been nonabsorbable in nature. Most of these case reports have documented only a few months of clinical follow-up...
  53. ncbi Prader-Willi syndrome: clinical genetics, cytogenetics and molecular biology
    Douglas C Bittel
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, and University of Missouri Kansas City School of Medicine, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Expert Rev Mol Med 7:1-20. 2005
    ..Here, we describe the clinical presentation of PWS, review the current understanding of causative cytogenetic and molecular genetic mechanisms, and discuss future directions for research...
  54. ncbi Chronic gastritis is not associated with gastric dysrhythmia or delayed solid emptying in children with dyspepsia
    Craig A Friesen
    Gastroenterology, Children s Mercy Hospital, Kansas City, Missouri 64108, USA
    Dig Dis Sci 50:1012-8. 2005
    ..Chronic gastritis and gastric dysrhythmia may simply be two separate and distinct mechanisms resulting in the clinical entity of dyspepsia...
  55. pmc Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations
    M G Butler
    Section of Medical Genetics and Molecular Medicine, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, MO, USA
    J Med Genet 42:318-21. 2005
    ..We suggest that PTEN gene testing be considered for patients with autistic behaviour and extreme macrocephaly. The gene findings may impact on recurrence risks as well as medical management for the patient...
  56. ncbi How frequent are asthma exacerbations in a pediatric primary care setting and do written asthma action plans help in their management?
    Chitra Dinakar
    Department of Allergy, Asthma, and Immunology, Children s Mercy Hospital and Clinics, Kansas City, Missouri 64108, USA
    J Asthma 41:807-12. 2004
    ..We aim to determine exacerbation frequency and usefulness of the asthma action plan in managing exacerbations that occur in a pediatric primary care setting...
  57. ncbi Surveys: a tool to provoke thought and identify areas of need
    Alan S Gamis
    Division of Hematology Oncology, Children s Mercy Hospital, 2401 Gillham Rd, Kansas City, MO 64108, USA
    Pediatr Blood Cancer 44:205-6. 2005
  58. ncbi Safety of infliximab treatment in pediatric patients with inflammatory bowel disease
    Craig A Friesen
    Section of Gastroenterology, The Children s Mercy Hospital and Clinics, Kansas City, Missouri 64108, USA
    J Pediatr Gastroenterol Nutr 39:265-9. 2004
    ..Infliximab appears to be efficacious in the treatment of pediatric Crohn disease (CD). There are few large-scale pediatric studies on the complications of infliximab therapy...
  59. ncbi Preschool outcome of less than 801-gram preterm infants compared with full-term siblings
    Howard W Kilbride
    Section of Neonatal Medicine, Department of Pediatrics, Children s Mercy Hospitals and Clinics, University of Missouri Kansas City School of Medicine, Kansas City, Missouri 64108, USA
    Pediatrics 113:742-7. 2004
    ..The objective of this study was to clarify the effects of prematurity separate from environmental factors on growth and neurodevelopmental outcomes by comparing ELBW children with their full-term siblings...
  60. ncbi Enteritis necroticans with recurrent enterocutaneous fistulae caused by Clostridium perfringens in a child with cyclic neutropenia
    Ding You Li
    Children s Mercy Hospital, Kansas City, Missouri 64108, USA
    J Pediatr Gastroenterol Nutr 38:213-5. 2004
  61. ncbi Antibiotic treatment for urinary tract infections in pediatric patients
    S Hellerstein
    Section of Nephrology, The Children s Mercy Hospital, University of Missouri Kansas City, Kansas City, MO 64108, USA
    Minerva Pediatr 55:395-406. 2003
    ..If the response is satisfactory and the culture shows an organism susceptible to the antibiotic used, complete 5 to 7 days of treatment with the oral antibiotic...
  62. ncbi Investigation of terbinafine as a CYP2D6 inhibitor in vivo
    S M Abdel-Rahman
    Children s Mercy Hospital, and the Department of Pediatrics, Pharmacy Practice, Pharmacology, and the Pharmaceutical Sciences, University of Missouri Kansas City, 64108, USA
    Clin Pharmacol Ther 65:465-72. 1999
    ..This prospective open-label study was designed to confirm our previous finding that terbinafine may inhibit CYP2D6...

Research Grants26

  1. Chronic Renal Insufficiency in NAPRTCS Patients
    Bradley Warady; Fiscal Year: 2007
    ..abstract_text> ..
  2. FUNGAL PROTEIN/GLYCOPROTEIN EXPRESSION IN TINEA CAPITIS
    Susan Abdel Rahman; Fiscal Year: 2003
    ..abstract_text> ..
  3. Evaluating Trichophyton tonsurans Carriage and Infection
    Susan Abdel Rahman; Fiscal Year: 2006
    ..abstract_text> ..
  4. CHILDREN'S CENTER FOR CLINICAL PHARMACOLOGY STUDIES
    Gregory Kearns; Fiscal Year: 2007
    ..abstract_text> ..
  5. Ontogeny of Drug Bioactivation and Idiosyncratic ADRs
    JAMES LEEDER; Fiscal Year: 2007
    ..abstract_text> ..
  6. PATHOGENESIS OF ANTICONVULSANT HYPERSENSITIVITY SYNDROME
    JAMES LEEDER; Fiscal Year: 2003
    ..It is anticipated that the basic experimental paradigm employed for these studies can also be applied to other idiosyncratic toxicities with suspected drug bioactivation and immune etiologies. ..
  7. Exogenous and Endogenous Biomarkers of CYP2D6 Variability in Pediatrics
    YVONNE SARAH LIN; Fiscal Year: 2010
    ..Ultimately, the goal of the research is to personalize the use of medications in children by selecting the appropriate dose of the correct medication for individual patients. ..
  8. Tools for mapping transcriptional networks
    Uri Alon; Fiscal Year: 2006
    ..We expect that the analysis tools and concepts developed in E. coli will be very useful in mapping complex regulatory circuits in other cell types. ..
  9. TLR's, Nitric Oxide and Chronic Lung Disease
    William Truog; Fiscal Year: 2005
    ..Its results may also open up intriguing pathways for treatments aimed at selective diminution of pulmonary inflammation. ..
  10. Development of Novel Therapeutic Strategy for Sickle Ce*
    EMFEMWONKIEKIE IYAMU; Fiscal Year: 2007
    ..Such an environment maximizes the potential for the P.I. to establish a scientific niche from which an academic career can be constructed. ..
  11. Sex, SLE, and Signal Transduction
    Jill Jacobson; Fiscal Year: 2005
    ..abstract_text> ..
  12. Effect of Diet on Drug Metabolism in Infants
    Michael Blake; Fiscal Year: 2003
    ..abstract_text> ..
  13. Sequence Based FISH Analysis of Philadelphia Chromosomes
    JOAN KNOLL; Fiscal Year: 2003
    ..Our long range goal is to classify patients based on the sites of translocation and deletion size, and then to determine if the disease complications can be attributed to the loss of specific genes adjacent to ABL1. ..