S Michele Owen

Summary

Affiliation: Centers for Disease Control and Prevention
Country: USA

Publications

  1. doi request reprint Testing for acute HIV infection: implications for treatment as prevention
    S Michele Owen
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Curr Opin HIV AIDS 7:125-30. 2012
  2. doi request reprint Performance of an alternative laboratory-based algorithm for HIV diagnosis in a high-risk population
    Kevin P Delaney
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E 46, Atlanta, GA 30333, USA
    J Clin Virol 52:S5-10. 2011
  3. pmc Performance of a fourth-generation HIV screening assay and an alternative HIV diagnostic testing algorithm
    Muazzam Nasrullah
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    AIDS 27:731-7. 2013
  4. doi request reprint Comparative evaluation of Aptima HIV-1 Qualitative RNA assay performance using plasma and serum specimens from persons with established HIV-1 infection
    Steven F Ethridge
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd MS E46, Atlanta, GA 30333, USA
    J Clin Virol 52:S63-6. 2011
  5. pmc Rapid detection and differentiation of antibodies to HIV-1 and HIV-2 using multivalent antigens and magnetic immunochromatography testing
    Timothy C Granade
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop A 25, Atlanta, GA 30333, USA
    Clin Vaccine Immunol 17:1034-9. 2010
  6. doi request reprint Performance of an alternative laboratory-based algorithm for diagnosis of HIV infection utilizing a third generation immunoassay, a rapid HIV-1/HIV-2 differentiation test and a DNA or RNA-based nucleic acid amplification test in persons with established H
    Laura G Wesolowski
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE MS E 46, Atlanta, GA 30333, USA
    J Clin Virol 52:S45-9. 2011
  7. doi request reprint Performance of the Alere Determine™ HIV-1/2 Ag/Ab Combo Rapid Test with specimens from HIV-1 seroconverters from the US and HIV-2 infected individuals from Ivory Coast
    Silvina Masciotra
    Laboratory Branch, Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    J Clin Virol 58:e54-8. 2013
  8. doi request reprint Comparison of HIV oral fluid and plasma antibody results during early infection in a longitudinal Nigerian cohort
    Wei Luo
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD and TB Prevention, Atlanta, GA 30333, United States Electronic address
    J Clin Virol 58:e113-8. 2013
  9. doi request reprint Comparison of alternative interpretive criteria for the HIV-1 Western blot and results of the Multispot HIV-1/HIV-2 Rapid Test for classifying HIV-1 and HIV-2 infections
    Muazzam Nasrullah
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Mailstop E46, Atlanta, GA 30333, USA
    J Clin Virol 52:S23-7. 2011
  10. doi request reprint Evaluation of supplemental testing with the Multispot HIV-1/HIV-2 Rapid Test and APTIMA HIV-1 RNA Qualitative Assay to resolve specimens with indeterminate or negative HIV-1 Western blots
    Laurie Linley
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, United States Electronic address
    J Clin Virol 58:e108-12. 2013

Collaborators

Detail Information

Publications31

  1. doi request reprint Testing for acute HIV infection: implications for treatment as prevention
    S Michele Owen
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Curr Opin HIV AIDS 7:125-30. 2012
    ..The aim of this study is to give an overview of the recent literature related to HIV testing with an emphasis on detecting acute HIV infection. Testing technology as well as implications for treatment as prevention will be discussed...
  2. doi request reprint Performance of an alternative laboratory-based algorithm for HIV diagnosis in a high-risk population
    Kevin P Delaney
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS E 46, Atlanta, GA 30333, USA
    J Clin Virol 52:S5-10. 2011
    ..Recently, an alternative diagnostic algorithm was proposed to more accurately identify early HIV-1 infection and differentiate between HIV-1 and HIV-2 infection...
  3. pmc Performance of a fourth-generation HIV screening assay and an alternative HIV diagnostic testing algorithm
    Muazzam Nasrullah
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    AIDS 27:731-7. 2013
    ....
  4. doi request reprint Comparative evaluation of Aptima HIV-1 Qualitative RNA assay performance using plasma and serum specimens from persons with established HIV-1 infection
    Steven F Ethridge
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd MS E46, Atlanta, GA 30333, USA
    J Clin Virol 52:S63-6. 2011
    ....
  5. pmc Rapid detection and differentiation of antibodies to HIV-1 and HIV-2 using multivalent antigens and magnetic immunochromatography testing
    Timothy C Granade
    Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop A 25, Atlanta, GA 30333, USA
    Clin Vaccine Immunol 17:1034-9. 2010
    ..MICT can provide a rapid, low-cost method of determining HIV antibody status requiring no subjective interpretations...
  6. doi request reprint Performance of an alternative laboratory-based algorithm for diagnosis of HIV infection utilizing a third generation immunoassay, a rapid HIV-1/HIV-2 differentiation test and a DNA or RNA-based nucleic acid amplification test in persons with established H
    Laura G Wesolowski
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE MS E 46, Atlanta, GA 30333, USA
    J Clin Virol 52:S45-9. 2011
    ..An alternative diagnostic algorithm has been proposed to detect early HIV-1 infection and differentiate HIV-1 from HIV-2...
  7. doi request reprint Performance of the Alere Determine™ HIV-1/2 Ag/Ab Combo Rapid Test with specimens from HIV-1 seroconverters from the US and HIV-2 infected individuals from Ivory Coast
    Silvina Masciotra
    Laboratory Branch, Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    J Clin Virol 58:e54-8. 2013
    ..The Alere Determine™ HIV-1/2 Ag/Ab Combo (Determine Combo) RT detects and distinguishes HIV p24 Antigen (Ag) from Antibody (Ab) to HIV-1+HIV-2 and thus has the potential to improve diagnosis of acute HIV infection...
  8. doi request reprint Comparison of HIV oral fluid and plasma antibody results during early infection in a longitudinal Nigerian cohort
    Wei Luo
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD and TB Prevention, Atlanta, GA 30333, United States Electronic address
    J Clin Virol 58:e113-8. 2013
    ..Oral fluid (OF) testing is a less-invasive alternative to blood-based testing for HIV. The performance of HIV OF tests has not been extensively evaluated in serially collected paired specimens from seroconverters...
  9. doi request reprint Comparison of alternative interpretive criteria for the HIV-1 Western blot and results of the Multispot HIV-1/HIV-2 Rapid Test for classifying HIV-1 and HIV-2 infections
    Muazzam Nasrullah
    Division of HIV AIDS Prevention, National Center for HIV, Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Mailstop E46, Atlanta, GA 30333, USA
    J Clin Virol 52:S23-7. 2011
    ..HIV-1 and HIV-2 infections may be identified using assays designed to differentiate HIV-1 and HIV-2 antibody reactivity...
  10. doi request reprint Evaluation of supplemental testing with the Multispot HIV-1/HIV-2 Rapid Test and APTIMA HIV-1 RNA Qualitative Assay to resolve specimens with indeterminate or negative HIV-1 Western blots
    Laurie Linley
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, United States Electronic address
    J Clin Virol 58:e108-12. 2013
    ..The use of Western blot (WB) as a supplemental test after reactive sensitive initial assays can lead to inconclusive or misclassified HIV test results, delaying diagnosis...
  11. doi request reprint Evaluation of the CDC proposed laboratory HIV testing algorithm among men who have sex with men (MSM) from five US metropolitan statistical areas using specimens collected in 2011
    Silvina Masciotra
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    J Clin Virol 58:e8-e12. 2013
    ..Discordant results in the proposed algorithm are resolved by nucleic acid-amplification testing (NAAT)...
  12. doi request reprint Evaluation of the performance of the Abbott ARCHITECT HIV Ag/Ab Combo Assay
    Pollyanna Chavez
    Division of HIV AIDS Prevention, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Virol 52:S51-5. 2011
    ..One such assay, the ARCHITECT(®) HIV Ag/Ab Combo Assay (ARCHITECT), has recently been approved by the Food and Drug Administration (FDA) for use in the United States...
  13. doi request reprint Development and characterization of a bead-based, multiplex assay for estimation of recent HIV type 1 infection
    Kelly A Curtis
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    AIDS Res Hum Retroviruses 28:188-97. 2012
    ....
  14. doi request reprint A rapid real-time PCR assay for the detection of HIV-1 proviral DNA using double-stranded primer
    Chou Pong Pau
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, United States
    J Virol Methods 164:55-62. 2010
    ..This assay may be useful as an alternative confirmation test in a variety of HIV testing venues...
  15. pmc Isothermal amplification using a chemical heating device for point-of-care detection of HIV-1
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 7:e31432. 2012
    ....
  16. doi request reprint Reference panel of cloned HIV-2 plasmid DNA for nucleic acid assay development, evaluation, and quality monitoring
    Ae S Youngpairoj
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    J Clin Virol 61:293-7. 2014
    ..A major limitation in the development of novel HIV-2 diagnostic assays is the lack of reference materials that can be used to evaluate, optimize, and monitor assay performance...
  17. pmc Inter-laboratory assessment of a prototype multiplex kit for determination of recent HIV-1 infection
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 8:e77765. 2013
    ..We recently described the development of a customized, HIV-1-specific Bio-Plex assay that allows for the measurement of HIV-specific antibody levels and avidity to multiple analytes for improved HIV-1 incidence estimates...
  18. pmc Evaluation of a multiplex assay for estimation of HIV-1 incidence
    Kelly A Curtis
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 8:e64201. 2013
    ..We sought to further optimize a previously described bead-based, HIV-1-specific multiplex assay with the capability of measuring multiple immune responses for determining recent infection...
  19. doi request reprint Evaluation of an alternative HIV diagnostic algorithm using specimens from seroconversion panels and persons with established HIV infections
    Silvina Masciotra
    Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Atlanta, GA 30333, USA
    J Clin Virol 52:S17-22. 2011
    ..Concordant positive results indicate HIV-positive specimens and discordant results are resolved by nucleic acid amplification testing (NAAT)...
  20. doi request reprint Performance evaluation of the CHEMBIO DPP® (dual path platform) HIV-1/2 assay in early and established infections
    Silvina Masciotra
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States Electronic address
    J Clin Virol 70:97-100. 2015
    ..S. that also received the Clinical Laboratory Improvement Amendments (CLIA) waiver for use with oral fluid and fingerstick and venous whole blood...
  21. pmc Nucleic acid testing by public health referral laboratories for public health laboratories using the U.S. HIV diagnostic testing algorithm
    Laura G Wesolowski
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS E 46, Atlanta, GA 30333, USA Electronic address
    J Clin Virol 65:6-10. 2015
    ..HIV laboratory testing algorithm do not have a nucleic acid test (NAT), which is needed when the third- or fourth-generation HIV screening immunoassay is reactive and the antibody-based supplemental test is non-reactive or indeterminate...
  22. pmc Real-Time Detection of HIV-2 by Reverse Transcription-Loop-Mediated Isothermal Amplification
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Clin Microbiol 52:2674-6. 2014
    ....
  23. pmc Detection of Acute HIV-1 Infection by RT-LAMP
    Donna L Rudolph
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, United States of America
    PLoS ONE 10:e0126609. 2015
    ..In addition, early knowledge of HIV status could lead to reduced high-risk behavior at a time when individuals are at a higher risk for transmitting the virus. ..
  24. doi request reprint Longitudinal analysis of HIV-1-specific antibody responses
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    AIDS Res Hum Retroviruses 30:1099-105. 2014
    ..As expected, IgG3 reactivity declined with disease progression and decreasing CD4(+) T cell count in the MSM cohort; however, 37% of the study subjects exhibited relatively high IgG3 levels late in the course of infection...
  25. doi request reprint HIV reverse-transcriptase drug resistance mutations during early infection reveal greater transmission diversity than in envelope sequences
    Jonathan T Lipscomb
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia
    J Infect Dis 210:1827-37. 2014
    ..We screened for DRMs during early-acute viremia and examined the diversity in reverse transcriptase (RT) relative to envelope (env) in cases of transmitted drug resistance...
  26. pmc Evaluation of dried blood spots with a multiplex assay for measuring recent HIV-1 infection
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America
    PLoS ONE 9:e107153. 2014
    ..The correlation in assay measures between plasma and DBS indicate that the sample types can be used interchangeably with the Bio-Plex format, without negatively impacting the misclassification rate of the assay. ..
  27. doi request reprint Sequence-specific detection method for reverse transcription, loop-mediated isothermal amplification of HIV-1
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Med Virol 81:966-72. 2009
    ....
  28. doi request reprint Evaluation of the performance characteristics of 6 rapid HIV antibody tests
    Kevin P Delaney
    Division of HIV AIDS Prevention Surveillance and Epidemiology, National Center for HIV, Viral Hepatitis, STD and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA, USA
    Clin Infect Dis 52:257-63. 2011
    ..Since 2002, the US Food and Drug Administration has approved 6 rapid human immunodeficiency virus (HIV) tests for use in the United States. To date, there has been no direct comparison of the performance of all 6 tests...
  29. doi request reprint Delayed maturation of antibody avidity but not seroconversion in rhesus macaques infected with simian HIV during oral pre-exposure prophylaxis
    Kelly A Curtis
    Laboratory Branch, Division of HIV AIDS Prevention, National Center for HIV AIDS, Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Acquir Immune Defic Syndr 57:355-62. 2011
    ....
  30. pmc Repeat confirmatory testing for persons with discordant whole blood and oral fluid rapid HIV test results: findings from post marketing surveillance
    Laura G Wesolowski
    Division of HIV AIDS Prevention, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    PLoS ONE 3:e1524. 2008
    ..Previous reports have not described whether repeat testing adequately resolves the HIV-infection status of persons with discordant results...
  31. doi request reprint Rapid detection of HIV-1 p24 antigen using magnetic immuno-chromatography (MICT)
    Shon Workman
    Centers for Disease Control and Prevention, National Center for HIV AIDS, Atlanta, GA 30333, United States
    J Virol Methods 160:14-21. 2009
    ..MICT could provide a simple, low-cost, and portable method for rapid HIV-1 p24 detection in a variety of testing environments...