C Noel Bairey Merz

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. ncbi request reprint Assessment of patients at intermediate cardiac risk
    Noel Bairey Merz
    Preventive and Rehabilitative Cardiac Center and the Women s Health Program, Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center Research Institute, Los Angeles, California 90048, USA
    Am J Cardiol 96:2J-10J. 2005
  2. pmc A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve
    C Noel Bairey Merz
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, CA, USA
    Eur Heart J 37:1504-13. 2016
  3. pmc Brachial artery constriction during brachial artery reactivity testing predicts major adverse clinical outcomes in women with suspected myocardial ischemia: results from the NHLBI-sponsored women's ischemia Syndrome Evaluation (WISE) Study
    Tara L Sedlak
    Department of Medicine, Vancouver General Hospital, Vancouver, British Columbia, Canada
    PLoS ONE 8:e74585. 2013
  4. pmc Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation
    Michael A Pacanowski
    Department of Pharmacy Practice and Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, FL, USA
    J Transl Med 6:11. 2008
  5. pmc Psychosocial stress and cardiovascular disease: pathophysiological links
    C Noel Bairey Merz
    Cedars Sinai Medical Center, University of California Los Angeles, School of Medicine, USA
    Behav Med 27:141-7. 2002
  6. ncbi request reprint Summary and conclusions
    Noel Bairey Merz
    Preventive and Rehabilitative Cardiac Center and the Women s Health Program, Division of Cardiology, Department of Medicine, Cedars Sinai Medical Research Institute, Los Angeles, California 90048, USA
    Am J Cardiol 96:40J-41J. 2005
  7. ncbi request reprint Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular cor
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 47:S21-9. 2006
  8. pmc Importance of socioeconomic status as a predictor of cardiovascular outcome and costs of care in women with suspected myocardial ischemia. Results from the National Institutes of Health, National Heart, Lung and Blood Institute-sponsored Women's Ischemia
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    J Womens Health (Larchmt) 17:1081-92. 2008
  9. pmc Timing of hormone therapy, type of menopause, and coronary disease in women: data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    Chrisandra L Shufelt
    Division of Cardiology, Heart Institute and Department of Medicine, Cedars Sinai Medical Center, 444 S San Vicente Blvd, Los Angeles, CA 90048, USA
    Menopause 18:943-50. 2011
  10. ncbi request reprint The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome Evaluation
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif, USA
    Circulation 114:894-904. 2006

Detail Information

Publications86

  1. ncbi request reprint Assessment of patients at intermediate cardiac risk
    Noel Bairey Merz
    Preventive and Rehabilitative Cardiac Center and the Women s Health Program, Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center Research Institute, Los Angeles, California 90048, USA
    Am J Cardiol 96:2J-10J. 2005
    ..Detailed case studies are presented that illustrate the use of these assessment tools in patients at intermediate risk...
  2. pmc A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and myocardial perfusion reserve
    C Noel Bairey Merz
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, CA, USA
    Eur Heart J 37:1504-13. 2016
    ..The aim of this study was to mechanistically test short-term late sodium current inhibition (ranolazine) in such subjects on angina, myocardial perfusion reserve index, and diastolic filling...
  3. pmc Brachial artery constriction during brachial artery reactivity testing predicts major adverse clinical outcomes in women with suspected myocardial ischemia: results from the NHLBI-sponsored women's ischemia Syndrome Evaluation (WISE) Study
    Tara L Sedlak
    Department of Medicine, Vancouver General Hospital, Vancouver, British Columbia, Canada
    PLoS ONE 8:e74585. 2013
    ..Limited brachial artery (BA) flow-mediated dilation during brachial artery reactivity testing (BART) has been linked to increased cardiovascular risk. We report on the phenomenon of BA constriction (BAC) following hyperemia...
  4. pmc Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation
    Michael A Pacanowski
    Department of Pharmacy Practice and Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, FL, USA
    J Transl Med 6:11. 2008
    ..Adrenergic gene polymorphisms are associated with cardiovascular and metabolic phenotypes. We investigated the influence of adrenergic gene polymorphisms on cardiovascular risk in women with suspected myocardial ischemia...
  5. pmc Psychosocial stress and cardiovascular disease: pathophysiological links
    C Noel Bairey Merz
    Cedars Sinai Medical Center, University of California Los Angeles, School of Medicine, USA
    Behav Med 27:141-7. 2002
    ....
  6. ncbi request reprint Summary and conclusions
    Noel Bairey Merz
    Preventive and Rehabilitative Cardiac Center and the Women s Health Program, Division of Cardiology, Department of Medicine, Cedars Sinai Medical Research Institute, Los Angeles, California 90048, USA
    Am J Cardiol 96:40J-41J. 2005
  7. ncbi request reprint Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular cor
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 47:S21-9. 2006
    ..Additionally, innovative cardiovascular imaging techniques will be discussed. Finally, we identify critical areas of further inquiry needed to advance this new gender-specific IHD understanding into improved outcomes for women...
  8. pmc Importance of socioeconomic status as a predictor of cardiovascular outcome and costs of care in women with suspected myocardial ischemia. Results from the National Institutes of Health, National Heart, Lung and Blood Institute-sponsored Women's Ischemia
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    J Womens Health (Larchmt) 17:1081-92. 2008
    ..For women, who are more likely to live in poverty, defining the clinical and economic impact of socioeconomic factors may aid in defining redistributive policies to improve healthcare quality...
  9. pmc Timing of hormone therapy, type of menopause, and coronary disease in women: data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    Chrisandra L Shufelt
    Division of Cardiology, Heart Institute and Department of Medicine, Cedars Sinai Medical Center, 444 S San Vicente Blvd, Los Angeles, CA 90048, USA
    Menopause 18:943-50. 2011
    ..The aim of this study was to assess the relationship of the timing of hormone therapy (HT) use with angiographic coronary artery disease (CAD) and cardiovascular disease (CVD) events in women with natural versus surgical menopause...
  10. ncbi request reprint The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome Evaluation
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif, USA
    Circulation 114:894-904. 2006
    ..Few data exist regarding the type and intensity of resource consumption in women with chest pain after coronary angiography...
  11. pmc Relations between endogenous androgens and estrogens in postmenopausal women with suspected ischemic heart disease
    Glenn D Braunstein
    Department of Medicine, Room 2119, Plaza Level, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 93:4268-75. 2008
    ..If so, then epidemiologic studies that examine the association between androgens and pathological processes should adjust the results for the independent effect of estrogens...
  12. ncbi request reprint Electrocardiographic predictors of cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE) study
    Brian Triola
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Am Coll Cardiol 46:51-6. 2005
    ..We sought to analyze the value of infrequently measured parameters of the 12-lead electrocardiogram (ECG) in predicting cardiovascular events in women with suspected myocardial ischemia who were referred for cardiac catheterization...
  13. pmc A randomized controlled trial of low-dose hormone therapy on myocardial ischemia in postmenopausal women with no obstructive coronary artery disease: results from the National Institutes of Health/National Heart, Lung, and Blood Institute-sponsored Women'
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am Heart J 159:987.e1-7. 2010
    ..We postulate that a 12-week duration of low-dose hormone replacement therapy is associated with myocardial ischemia and endothelial dysfunction...
  14. pmc Safety of coronary reactivity testing in women with no obstructive coronary artery disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) study
    Janet Wei
    Division of Cardiology, Women s Heart Center, Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    JACC Cardiovasc Interv 5:646-53. 2012
    ..This study evaluated the safety of coronary reactivity testing (CRT) in symptomatic women with evidence of myocardial ischemia and no obstructive coronary artery disease (CAD)...
  15. pmc Comorbid depression and anxiety symptoms as predictors of cardiovascular events: results from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) study
    Thomas Rutledge
    VA San Diego Healthcare Syste, University of California, San Diego, San Diego, California, USA
    Psychosom Med 71:958-64. 2009
    ..Although these symptoms commonly co-occur in medical patients, little is known about combined effects of depression and anxiety on CVD risk...
  16. ncbi request reprint Depression, the metabolic syndrome and cardiovascular risk
    Viola Vaccarino
    Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
    Psychosom Med 70:40-8. 2008
    ..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
  17. pmc Cardiovascular Disease and 10-Year Mortality in Postmenopausal Women with Clinical Features of Polycystic Ovary Syndrome
    C Noel Bairey Merz
    1 Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California
    J Womens Health (Larchmt) 25:875-81. 2016
    ..Women with polycystic ovary syndrome (PCOS) have greater cardiac risk factor clustering but the link with mortality is incompletely described...
  18. pmc Red versus white wine as a nutritional aromatase inhibitor in premenopausal women: a pilot study
    Chrisandra Shufelt
    Women s Heart Center, The Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Womens Health (Larchmt) 21:281-4. 2012
    ..Aromatase inhibitors (AIs) prevent the conversion of androgens to estrogen and occur naturally in grapes, grape juice, and red, but not white wine. We tested whether red wine is a nutritional AI in premenopausal women...
  19. pmc Sex hormones and the QT interval: a review
    Tara Sedlak
    Women s Heart Center, Division of Cardiology, Department of Medicine, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, 444 S San Vicente Boulevard, Los Angeles, CA 90048, USA
    J Womens Health (Larchmt) 21:933-41. 2012
    ..Further, we review the potential mechanisms and pathophysiology of sex hormones on the QT interval...
  20. ncbi request reprint Depression is associated with cardiac symptoms, mortality risk, and hospitalization among women with suspected coronary disease: the NHLBI-sponsored WISE study
    Thomas Rutledge
    University of California, San Diego, CA, USA
    Psychosom Med 68:217-23. 2006
    ..In this study, we examined the association between depression measured in terms of symptom severity and treatment history, cardiac symptom presentation, and clinical outcomes among a sample of women with suspected myocardial ischemia...
  21. pmc Provocative testing for coronary reactivity and spasm
    Melody Zaya
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, California
    J Am Coll Cardiol 63:103-9. 2014
    ..Numerous agents have been historically described for provocative testing. We provide a review of published data for the role of provocation testing in the diagnosis of coronary spasm...
  22. pmc Differing Relations to Early Atherosclerosis between Vitamin C from Supplements vs. Food in the Los Angeles Atherosclerosis Study: A Prospective Cohort Study
    Megha Agarwal
    Women s Heart Center, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Open Cardiovasc Med J 6:113-21. 2012
    ..To determine the relationship of vitamin c intake from supplements vs food on early atherosclerosis detected by carotid intima media thickness (IMT)...
  23. pmc A pilot randomized, single-blind, placebo-controlled trial of traditional acupuncture for vasomotor symptoms and mechanistic pathways of menopause
    Jeannette M Painovich
    Department of Medicine, Cedars Sinai Heart Institute, Los Angeles, CA 90048, USA
    Menopause 19:54-61. 2012
    ....
  24. doi request reprint Diastolic dysfunction measured by cardiac magnetic resonance imaging in women with signs and symptoms of ischemia but no obstructive coronary artery disease
    Janet Wei
    Barbara Streisand Women s Heart Center, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, United States
    Int J Cardiol 220:775-80. 2016
    ..The relationship between CMD and diastolic function measured by cardiac magnetic resonance imaging (CMR) is not well described...
  25. pmc Smoking status and common carotid artery intima-medial thickness among middle-aged men and women based on ultrasound measurement: a cohort study
    Amy Z Fan
    Prevention Research Center, Pacific Institute for Research and Evaluation, Berkeley, CA, USA
    BMC Cardiovasc Disord 6:42. 2006
    ..Cigarette smoking is an established causal factor for atherosclerosis. However, the smoking effect on different echogenic components of carotid arterial wall measured by ultrasound is not well elucidated...
  26. pmc Carotid artery distensibility and hormone therapy and menopause: the Los Angeles Atherosclerosis Study
    Chrisandra Shufelt
    1Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, and Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 2University of Pittsburgh, Pittsburgh, PA 3Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, AL 4Department of Obstetrics and Gynecology, Wake Forest School of Medicine, Winston Salem, NC 5Departments of Obstetrics and Gynecology and Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 6Department of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA
    Menopause 23:150-7. 2016
    ..We prospectively studied distensibility and hormone therapy use at different menopause stages...
  27. ncbi request reprint Progression of carotid intima-media thickness and plasma antioxidants: the Los Angeles Atherosclerosis Study
    James H Dwyer
    Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Arterioscler Thromb Vasc Biol 24:313-9. 2004
    ..We assessed the association between atherosclerotic progression, measured by carotid intima-media thickness (IMT), and plasma levels of oxygenated and hydrocarbon carotenoids, tocopherols, retinol, and ascorbic acid...
  28. pmc Total estrogen time and obstructive coronary disease in women: insights from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE)
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Womens Health (Larchmt) 18:1315-22. 2009
    ..The aim of this study was to evaluate the relationships between detailed measurements of endogenous and exogenous estrogen exposure time with angiographic CAD and major adverse cardiovascular events...
  29. ncbi request reprint Past oral contraceptive use and angiographic coronary artery disease in postmenopausal women: data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute and Medical Center, Los Angeles, California, USA
    Fertil Steril 85:1425-31. 2006
    ..To evaluate past oral contraceptive use and angiographic coronary artery disease in women...
  30. ncbi request reprint Validation of the accuracy of pretest and exercise test scores in women with a low prevalence of coronary disease: the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) study
    Anthony P Morise
    Section of Cardiology, Department of Medicine, West Virginia University School of Medicine, Morgantown, WVa, USA
    Am Heart J 147:1085-92. 2004
    ..Pretest and exercise test scores derived for use in women without known CAD have not been tested in women with a low prevalence of CAD...
  31. ncbi request reprint Exercise treadmill testing using a modified exercise protocol in women with suspected myocardial ischemia: findings from the National Heart, Lung and Blood Institute-sponsored Women's Ischemia Syndrome Evaluation (WISE)
    Jannet F Lewis
    WISE Clinical Centers, Division of Cardiology, University of Florida, Gainesville, Fla, USA
    Am Heart J 149:527-33. 2005
    ..As part of the WISE, a modified protocol was examined with the intention of improving reliability of exercise testing...
  32. doi request reprint Stable angina in women: lessons from the National Heart, Lung and Blood Institute-sponsored Women’s Ischemia Syndrome Evaluation
    C Noel Bairey Merz
    Women s Heart Center, Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Cardiovasc Med (Hagerstown) 12:85-7. 2011
    ..Continued research is indicated to devise therapeutic regimens to improve symptom burden and reduce risk in women with IHD...
  33. pmc Diabetes mellitus, hypothalamic hypoestrogenemia, and coronary artery disease in premenopausal women (from the National Heart, Lung, and Blood Institute sponsored WISE study)
    Bina Ahmed
    Department of Medicine, Division of Cardiology, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Cardiol 102:150-4. 2008
    ..The presence of both DM and HHE predicted a greater burden of angiographic CAD. Prospective research is warranted to better understand causal relations between DM, endogenous hormones, and MACE in premenopausal women...
  34. doi request reprint Heart failure hospitalization in women with signs and symptoms of ischemia: A report from the women's ischemia syndrome evaluation study
    May Bakir
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, CA, USA
    Int J Cardiol 223:936-939. 2016
    ..We sought to verify and characterize the HF hospitalizations...
  35. ncbi request reprint Cholesterol-lowering medication, cholesterol level, and reproductive hormones in women: the Women's Ischemia Syndrome Evaluation (WISE)
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    Am J Med 113:723-7. 2002
    ..We also sought to evaluate this association, independent of statin use, particularly among premenopausal women of childbearing age...
  36. ncbi request reprint Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 47:S4-S20. 2006
    ....
  37. ncbi request reprint Hypoestrogenemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE study
    C Noel Bairey Merz
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 41:413-9. 2003
    ..We sought to evaluate hypoestrogenemia of hypothalamic origin and its association with angiographic coronary artery disease (CAD) in premenopausal women...
  38. pmc Contraceptive hormone use and cardiovascular disease
    Chrisandra L Shufelt
    Women s Heart Center, Division of Cardiology, Department of Medicine, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 53:221-31. 2009
    ....
  39. ncbi request reprint Ethnic differences in the prognostic value of stress technetium-99m tetrofosmin gated single-photon emission computed tomography myocardial perfusion imaging
    Leslee J Shaw
    Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 45:1494-504. 2005
    ..This study was designed to evaluate the differential prognostic value of gated single-photon emission computed tomographic imaging (SPECT) imaging in an ethnically diverse multicenter registry...
  40. ncbi request reprint The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Am Coll Cardiol 47:S36-43. 2006
    ..Our objective was to determine the prognostic value of estimated metabolic equivalents (METs) based on self-reported functional capacity by the Duke Activity Status Index (DASI) in symptomatic women...
  41. pmc Proceedings from the scientific symposium: Sex differences in cardiovascular disease and implications for therapies
    C Noel Bairey Merz
    Women s Heart Center, Cedars Sinai Heart Institute, 444 S San Vincente Boulevard, Los Angeles, CA 90048, USA
    J Womens Health (Larchmt) 19:1059-72. 2010
    ....
  42. ncbi request reprint New insights into ischemic heart disease in women
    Antonio Bellasi
    Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA 30306, USA
    Cleve Clin J Med 74:585-94. 2007
    ..Needed is a strategy for detecting and assessing coronary disease specifically in women. This review highlights recent evidence on sex differences in coronary artery disease...
  43. pmc Nonacute coronary syndrome anginal chest pain
    Megha Agarwal
    Women s Heart Center, Heart Institute, Cedars Sinai Medical Center, 444 South San Vicente Boulevard, Suite 600, Los Angeles, CA 90048, USA
    Med Clin North Am 94:201-16. 2010
    ..This review focuses on the pathophysiology, diagnosis, and treatment of stable, non-ACS anginal chest pain...
  44. ncbi request reprint Social networks are associated with lower mortality rates among women with suspected coronary disease: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation study
    Thomas Rutledge
    University of California, San Diego, San Diego, California, USA
    Psychosom Med 66:882-8. 2004
    ..To examine the association between social relationships measured by the Social Network Scale and coronary artery disease (CAD) risk and mortality among a sample of women with suspected CAD...
  45. pmc The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE)
    Vera Bittner
    Department of Medicine, University of Alabama at Birmingham, USA
    Am Heart J 157:548-55. 2009
    ..The prognostic utility of the TG/HDL-C ratio, a marker for insulin resistance and small dense low-density lipoprotein particles, is unknown among high-risk women...
  46. pmc Towards elimination of the dark-rim artifact in first-pass myocardial perfusion MRI: removing Gibbs ringing effects using optimized radial imaging
    Behzad Sharif
    Biomedical Imaging Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California, USA
    Magn Reson Med 72:124-36. 2014
    ..A major source of DRAs is the "Gibbs ringing" effect. We propose an optimized radial acquisition strategy aimed at eliminating ringing-induced DRAs in FPP...
  47. doi request reprint Diastolic dysfunction: improved understanding using emerging imaging techniques
    Daniel Daneshvar
    Cedars Sinai Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am Heart J 160:394-404. 2010
    ....
  48. ncbi request reprint Gender differences in the link between depression and cardiovascular disease
    Tasneem Z Naqvi
    Division of Cardiology, Cedars Sinai Research Institute, Cedars Sinai Medical Center, University of California School of Medicine, Los Angeles, California, USA
    Psychosom Med 67:S15-8. 2005
    ..Whether effective treatment of depression lowers cardiac mortality remains to be proven...
  49. ncbi request reprint Effects of a randomized controlled trial of transcendental meditation on components of the metabolic syndrome in subjects with coronary heart disease
    Maura Paul-Labrador
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles 90048, USA
    Arch Intern Med 166:1218-24. 2006
    ..The aim of this study was to evaluate the efficacy of transcendental meditation (TM) on components of the metabolic syndrome and CHD...
  50. pmc DHEA-S levels and cardiovascular disease mortality in postmenopausal women: results from the National Institutes of Health--National Heart, Lung, and Blood Institute (NHLBI)-sponsored Women's Ischemia Syndrome Evaluation (WISE)
    Chrisandra Shufelt
    Heart Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 95:4985-92. 2010
    ..Low levels have been associated with increased cardiovascular disease (CVD) risk and all-cause mortality, although these results have not been consistently replicated, particularly in women...
  51. pmc Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute sponsored W
    Leslee J Shaw
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 93:1276-84. 2008
    ..Women with polycystic ovary syndrome (PCOS) have a greater clustering of cardiac risk factors. However, the link between PCOS and cardiovascular (CV) disease is incompletely described...
  52. ncbi request reprint Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE study
    Viola Vaccarino
    Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
    J Am Coll Cardiol 50:2044-50. 2007
    ..The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD)...
  53. pmc A randomized controlled trial of acupuncture in stable ischemic heart disease patients
    Puja K Mehta
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, CA, United States
    Int J Cardiol 176:367-74. 2014
    ..We evaluated the impact of traditional acupuncture (TA) on cardiac autonomic function measured by HRV in SIHD patients...
  54. doi request reprint Coronary microvascular dysfunction: sex-specific risk, diagnosis, and therapy
    Jenna Dean
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Cedars Sinai Medical Center, 127 South San Vicente Boulevard, A3600, Los Angeles, CA 90048, USA
    Nat Rev Cardiol 12:406-14. 2015
    ..In this Review, we discuss the prevalence, presentation, diagnosis, and treatment of coronary microvascular dysfunction, with a particular emphasis on ischaemic heart disease in women. ..
  55. doi request reprint Female-specific factors for IHD: across the reproductive lifespan
    Chrisandra Shufelt
    Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, 8631 W Third Street, Los Angeles, CA, 90048, USA
    Curr Atheroscler Rep 17:481. 2015
    ..Research continues to decipher the impact of estrogen decline at this stage and the effect of menopause hormone therapy as they relate to the cardiovascular health of menopausal women. ..
  56. pmc Hormone therapy dose, formulation, route of delivery, and risk of cardiovascular events in women: findings from the Women's Health Initiative Observational Study
    Chrisandra L Shufelt
    From the 1Barbra Streisand Women s Heart Center, Cedars Sinai Heart Institute, Los Angeles, CA 2Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 3National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 4MedStar Health Research Institute, Hyattsville, MD 5University of Florida College of Medicine Jacksonville, Jacksonville, FL 6Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 7George Washington University School of Medicine and Health Sciences, Washington, DC 8Atlanta VA Medical Center, Decatur, GA 9Division of Endocrinology and Metabolism, Department of Medicine, Emory University School of Medicine, Atlanta, GA and 10Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA
    Menopause 21:260-6. 2014
    ..This study directly compared different estrogen doses, routes of delivery, and HT formulations in postmenopausal women in relation to the risk of coronary heart disease (CHD), stroke, CVD mortality, total CVD, and all-cause mortality...
  57. ncbi request reprint Leisure time physical activity and early atherosclerosis: the Los Angeles Atherosclerosis Study
    Cheryl K Nordstrom
    Department of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Med 115:19-25. 2003
    ..We examined the relation between physical activity and 3-year progression of carotid atherosclerosis...
  58. pmc Effects of simvastatin on cardiac neural and electrophysiologic remodeling in rabbits with hypercholesterolemia
    Yen Bin Liu
    Department of Internal Medicine, Division of Cardiology, National Taiwan University Hospital and National Taiwan University School of Medicine, UCLA, Los Angeles, California, USA
    Heart Rhythm 6:69-75. 2009
    ..Significant cardiac neural and electrophysiologic remodeling occurs with hypercholesterolemia (HC). Whether simvastatin can reverse HC-induced remodeling is unclear...
  59. ncbi request reprint Physician attitudes and practices and patient awareness of the cardiovascular complications of diabetes
    C Noel Bairey Merz
    Preventive Cardiac Center and Women s Health Program, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 40:1877-81. 2002
    ..Studies were conducted to: 1) assess physicians' attitudes and practices in managing cardiovascular disease (CVD) risks in diabetes; and 2) determine the awareness of CVD risks among diabetic patients...
  60. ncbi request reprint The association of hormone replacement therapy and coronary calcium as determined by electron beam tomography
    Enrique F Schisterman
    Departments of Imaging Division of Nuclear Medicine, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Womens Health Gend Based Med 11:631-8. 2002
    ..Examination of the association between coronary calcium (CC), a marker of atherosclerotic plaque burden, and the use of HRT in postmenopausal women may help address this paradox...
  61. ncbi request reprint Some thoughts on the vasculopathy of women with ischemic heart disease
    Carl J Pepine
    Division of Cardiovascular Medicine, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    J Am Coll Cardiol 47:S30-5. 2006
    ..A better understanding of these findings should provide direction for new algorithms to improve management of the vasculopathy underlying IHD in women...
  62. ncbi request reprint Carotid wall thickness and years since bilateral oophorectomy: the Los Angeles Atherosclerosis Study
    Kathleen M Dwyer
    Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, 98103, USA
    Am J Epidemiol 156:438-44. 2002
    ....
  63. ncbi request reprint Migraines, angiographic coronary artery disease and cardiovascular outcomes in women
    Bina Ahmed
    Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif, USA
    Am J Med 119:670-5. 2006
    ..There are conflicting data regarding the association between migraines and cardiovascular events. We evaluated the relationship between migraine headaches, angiographic coronary artery disease, and cardiovascular events in women...
  64. ncbi request reprint APOE polymorphism and angiographic coronary artery disease severity in the Women's Ischemia Syndrome Evaluation (WISE) study
    Qi Chen
    Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA 15261, USA
    Atherosclerosis 169:159-67. 2003
    ..These data support the hypothesis that the APOE*4 allele is an independent risk factor not only for the presence of CAD and hyperlipidemia, but also for the angiographic severity of CAD in white women with a family history of disease...
  65. ncbi request reprint Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease
    Qi Chen
    Department of Human Genetics, University of Pittsburgh, PA 15261, USA
    Circulation 107:3146-51. 2003
    ..We examined the association of 3 polymorphisms in the lectin-like oxidized LDL receptor-1 (LOX1 or OLR1) gene with coronary artery disease in the Women's Ischemia Syndrome Evaluation (WISE) study population...
  66. ncbi request reprint Effects of intensive versus moderate lipid-lowering therapy on myocardial ischemia in older patients with coronary heart disease: results of the Study Assessing Goals in the Elderly (SAGE)
    Prakash Deedwania
    UCSF School of Medicine, San Francisco, Calif, USA
    Circulation 115:700-7. 2007
    ..However, no studies to date have assessed intensive versus moderate statin therapy in older patients with stable coronary syndromes...
  67. ncbi request reprint Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study
    Carl J Pepine
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
    J Womens Health (Larchmt) 16:481-8. 2007
    ..Accordingly, we investigated the relationship between blood phytoestrogen levels and coronary reactivity in women with suspected myocardial ischemia referred for coronary angiography...
  68. ncbi request reprint Anger, hostility, and cardiac symptoms in women with suspected coronary artery disease: the Women's Ischemia Syndrome Evaluation (WISE) Study
    David S Krantz
    Department of Medical and Clinical Psychology, Uniformed Services University of Health Sciences, Bethesda, Maryland 20814, USA
    J Womens Health (Larchmt) 15:1214-23. 2006
    ..To determine the relationship of anger and hostility to angiographic coronary artery disease (CAD), symptoms, and functional status among women with suspected CAD...
  69. ncbi request reprint Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women: a report from the Women's Ischemia Syndrome Evaluation
    Oscar C Marroquin
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
    Circulation 109:714-21. 2004
    ..The interrelationship between metabolic status and CAD on cardiovascular risk in women is not known...
  70. ncbi request reprint Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)
    Gregory O von Mering
    University of Florida College of Medicine, Gainesville, Fla 32610 0277, USA
    Circulation 109:722-5. 2004
    ..Coronary vascular dysfunction has been linked to atherosclerosis and adverse cardiovascular outcomes in men, but these relationships have not been firmly established in women...
  71. ncbi request reprint Effects of oral magnesium therapy on exercise tolerance, exercise-induced chest pain, and quality of life in patients with coronary artery disease
    Michael Shechter
    The Heart Institute, Sheba Medical Center, Tel Hashomer, Israel
    Am J Cardiol 91:517-21. 2003
    ....
  72. ncbi request reprint Hormone replacement, race, and psychological health in women: a report from the NHLBI-Sponsored WISE Study
    Marian B Olson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Womens Health (Larchmt) 13:325-32. 2004
    ..We hypothesized that both groups of women would have fewer symptoms of depression and lower hostility scores associated with HRT use...
  73. ncbi request reprint Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women's Ischaemia Syndrome Evaluation (WISE) study
    B Delia Johnson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA, USA
    Eur Heart J 27:1408-15. 2006
    ..This study compared CV outcomes in women with persistent chest pain (PChP) vs. those without PChP...
  74. pmc Psychosocial stress and cardiovascular disease Part 2: effectiveness of the Transcendental Meditation program in treatment and prevention
    Kenneth G Walton
    Center for Natural Medicine and Prevention, Fairfield, IA 52556, USA
    Behav Med 28:106-23. 2002
    ..The magnitudes of these effects compare favorably with those of conventional interventions for secondary prevention...
  75. ncbi request reprint Hypertension, menopause, and coronary artery disease risk in the Women's Ischemia Syndrome Evaluation (WISE) Study
    Gretchen L Gierach
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Am Coll Cardiol 47:S50-8. 2006
    ..We evaluated whether the relationship between hypertension, other cardiac risk factors, and coronary artery disease (CAD) is modulated by menopausal status and/or age...
  76. pmc Lipid-lowering medication use and aggression scores in women: a report from the NHLBI-sponsored WISE study
    Marian B Olson
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Womens Health (Larchmt) 17:187-94. 2008
    ..The aim of this study was to examine the association between the use of lipid-lowering medication and aggressive responding, hostility, cynicism, and depression scores in women undergoing coronary angiography...
  77. ncbi request reprint Symptoms, myocardial ischaemia and quality of life in women: results from the NHLBI-sponsored WISE Study
    Marian B Olson
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Eur Heart J 24:1506-14. 2003
    ..Our goal was to evaluate health-related quality of life (QOL) in women undergoing angiography for suspected ischaemia...
  78. ncbi request reprint Obesity distribution and reproductive hormone levels in women: a report from the NHLBI-sponsored WISE Study
    Marian B Olson
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Womens Health (Larchmt) 15:836-42. 2006
    ..The purpose of this study was to evaluate body mass index (BMI) and waist circumference and the association of obesity distribution with blood estrogen levels (estradiol, bioavailable estradiol, and estrone)...
  79. ncbi request reprint Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease: results from the National Institutes of Health-National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)
    B Delia Johnson
    Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Circulation 109:2993-9. 2004
    ..The prognostic implications of these findings are unknown...
  80. ncbi request reprint Hemoglobin level is an independent predictor for adverse cardiovascular outcomes in women undergoing evaluation for chest pain: results from the National Heart, Lung, and Blood Institute Women's Ischemia Syndrome Evaluation Study
    Christopher B Arant
    University of Florida College of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida 32610 0277, USA
    J Am Coll Cardiol 43:2009-14. 2004
    ..This study was designed to investigate the relationship between hemoglobin level (Hgb) and adverse cardiovascular outcomes in women with suspected ischemia...
  81. ncbi request reprint Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)
    B Delia Johnson
    Graduate School of Public Health, University of Pittsburgh, Parran 127, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Circulation 109:726-32. 2004
    ..However, prior studies have yielded inconsistent results, and the independent predictive value of SAA for coronary artery disease (CAD) severity and cardiovascular events remains unclear...
  82. ncbi request reprint President's page: the promise of prevention: so, why aren't all cardiologists "preventive"?
    Michael J Wolk
    J Am Coll Cardiol 44:2082-4. 2004
  83. ncbi request reprint Angina with "normal" coronary arteries: a changing philosophy
    Raffaele Bugiardini
    Department of Internal Medicine, Cardio Angiology and Hepatology, University of Bologna, Bologna, Italy
    JAMA 293:477-84. 2005
    ..Many women with angina are told that they have no significant heart disease following demonstration of normal or near-normal coronary arteries and are offered no specific treatment beyond reassurance...
  84. ncbi request reprint Toward optimal health: the experts discuss cardiovascular disease. Interviewed by Jodi R. Godfrey
    C Noel Bairey Merz
    J Womens Health (Larchmt) 14:4-10. 2005
  85. ncbi request reprint Impaired coronary vascular reactivity and functional capacity in women: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE) Study
    Eileen Handberg
    Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
    J Am Coll Cardiol 47:S44-9. 2006
    ..We investigated the relationship between coronary vascular reactivity and functional capacity as assessed from the Duke Activity Status Index (DASI) in a cohort of women evaluated for suspected ischemia...
  86. ncbi request reprint Comparison of SWAN and WISE menopausal status classification algorithms
    Janet M Johnston
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Womens Health (Larchmt) 15:1184-94. 2006
    ..Most epidemiological studies, including the Study of Women's Health Across the Nation (SWAN), classify women based on self-reported bleeding history...