Xiuqing Guo

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. pmc Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene
    Michelle R Jones
    Division of Endocrinology, Diabetes and Metabolism, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 94:5034-8. 2009
  2. pmc Application of Bayesian regression with singular value decomposition method in association studies for sequence data
    Soonil Kwon
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    BMC Proc 5:S57. 2011
  3. ncbi request reprint The linkage information content value of polymorphism genetic markers in model-free linkage analysis
    Xiuqing Guo
    Division of Medical Genetics, Department of Medicine and Pediatrics, Spielberg Pediatrics Research Center, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    Hum Hered 53:45-8. 2002
  4. ncbi request reprint Cosegregation of albuminuria and blood pressure: the Insulin Resistance Atherosclerosis (IRAS) family study
    Xiuqing Guo
    Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Am J Hypertens 18:823-7. 2005
  5. ncbi request reprint Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study
    Xiuqing Guo
    Medical Genetics Institutes, Cedars Sinai Medical Center, 8700 Beverly Blvd, 665W, Los Angeles, CA 90048, USA
    Diabetes 55:1723-30. 2006
  6. ncbi request reprint Hypertension genes are genetic markers for insulin sensitivity and resistance
    Xiuqing Guo
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    Hypertension 45:799-803. 2005
  7. pmc Replication of calpain-10 genetic association with carotid intima-media thickness
    Mark O Goodarzi
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 205:503-5. 2009
  8. ncbi request reprint Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait
    Mark O Goodarzi
    Medical Genetics Institute, Department of Pediatrics, Steven Spielberg Pediatric Research Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Diabetes 54:1222-7. 2005
  9. ncbi request reprint Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Diabetes 54:1228-32. 2005
  10. ncbi request reprint The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Becker B 128, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 90:4816-23. 2005

Detail Information

Publications45

  1. pmc Independent confirmation of association between metabolic phenotypes of polycystic ovary syndrome and variation in the type 6 17beta-hydroxysteroid dehydrogenase gene
    Michelle R Jones
    Division of Endocrinology, Diabetes and Metabolism, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 94:5034-8. 2009
    ..Type 6 17beta-hydroxysteroid dehydrogenase (HSD17B6) gene expression is increased in PCOS ovarian theca. Previous genetic study of HSD17B6 reported significant association of rs898611 with PCOS risk and metabolic phenotypes...
  2. pmc Application of Bayesian regression with singular value decomposition method in association studies for sequence data
    Soonil Kwon
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    BMC Proc 5:S57. 2011
    ....
  3. ncbi request reprint The linkage information content value of polymorphism genetic markers in model-free linkage analysis
    Xiuqing Guo
    Division of Medical Genetics, Department of Medicine and Pediatrics, Spielberg Pediatrics Research Center, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    Hum Hered 53:45-8. 2002
    ..In this paper, we give corrected LIC values for full sib, grandparent-grandchild, first cousin and avuncular pairs, and indicate the availability of a computer program to calculate them...
  4. ncbi request reprint Cosegregation of albuminuria and blood pressure: the Insulin Resistance Atherosclerosis (IRAS) family study
    Xiuqing Guo
    Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Am J Hypertens 18:823-7. 2005
    ..Our aim in this study was to examine the familial aggregation of albuminuria and its phenotypic, genetic, and environmental correlations with BP in nondiabetic individuals of Hispanic (HA) and African American (AA) ethnicity...
  5. ncbi request reprint Genome-wide linkage of plasma adiponectin reveals a major locus on chromosome 3q distinct from the adiponectin structural gene: the IRAS family study
    Xiuqing Guo
    Medical Genetics Institutes, Cedars Sinai Medical Center, 8700 Beverly Blvd, 665W, Los Angeles, CA 90048, USA
    Diabetes 55:1723-30. 2006
    ..Therefore, a quantitative trait locus at 3q27, likely distinct from the APM1 gene, contributes to the variation of plasma adiponectin levels in the Hispanic-American population...
  6. ncbi request reprint Hypertension genes are genetic markers for insulin sensitivity and resistance
    Xiuqing Guo
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, Calif 90048, USA
    Hypertension 45:799-803. 2005
    ..Our data support the hypothesis that genes in the blood pressure pathway may play a role in insulin resistance in Mexican Americans...
  7. pmc Replication of calpain-10 genetic association with carotid intima-media thickness
    Mark O Goodarzi
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 205:503-5. 2009
    ..A prior study in Hispanics found association of haplotypes in the diabetes gene calpain-10 (CAPN10) with carotid artery intima-media thickness (CIMT). This study sought to replicate this association in an independent cohort...
  8. ncbi request reprint Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait
    Mark O Goodarzi
    Medical Genetics Institute, Department of Pediatrics, Steven Spielberg Pediatric Research Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Diabetes 54:1222-7. 2005
    ..We postulated that the processes of insulin action and insulin clearance in skeletal muscle are highly regulated and that AMPD1 function may play an important role in these phenomena...
  9. ncbi request reprint Association of the diabetes gene calpain-10 with subclinical atherosclerosis: the Mexican-American Coronary Artery Disease Study
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Diabetes 54:1228-32. 2005
    ..The fact that the diabetes gene CAPN10 also influences the risk for atherosclerosis shows that inherited factors may underlie the frequent co-occurrence of these two conditions...
  10. ncbi request reprint The 3' untranslated region of the lipoprotein lipase gene: haplotype structure and association with post-heparin plasma lipase activity
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Becker B 128, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 90:4816-23. 2005
    ..Haplotypes comprising six single nucleotide polymorphisms (SNPs) (intron 7 to intron 9) of the lipoprotein lipase (LPL) gene appear to influence risk for atherosclerosis and insulin resistance in Mexican-Americans...
  11. pmc Genome-wide linkage analysis using cross-sectional and longitudinal traits for body mass index in a subsample of the Framingham Heart Study
    Xiaohui Li
    Division of Medical Genetics, Medical Genetics Birth Defects Center, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles California, USA
    BMC Genet 4:S35. 2003
    ..There may be a QTL on chromosome 16 that contributes to BMI and this locus, and maybe others, is more likely to affect BMI during early adulthood...
  12. ncbi request reprint Haplotypes in the lipoprotein lipase gene influence fasting insulin and discovery of a new risk haplotype
    Mark O Goodarzi
    Cedars Sinai Medical Center, Division of Endocrinology, Diabetes, and Metabolism, 8700 Beverly Boulevard, Becker B 131, Los Angeles, California 90048, USA
    J Clin Endocrinol Metab 92:293-6. 2007
    ..The most common haplotype (haplotype 1) was protective, whereas the fourth most common haplotype (haplotype 4) conferred risk for insulin resistance and atherosclerosis...
  13. ncbi request reprint Carotid intima-media thickness (cIMT) cosegregates with blood pressure and renal function in hypertensive Hispanic families
    Yi Chun Chen
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Atherosclerosis 198:160-5. 2008
    ..Since cIMT is correlated with hypertension and microalbuminuria, we tested the hypothesis that there is a genetic basis for the observed relationship between cIMT, blood pressure (BP), and renal function within high risk families...
  14. ncbi request reprint Lipoprotein lipase is a gene for insulin resistance in Mexican Americans
    Mark O Goodarzi
    Division of Medical Genetics, Department of Pediatrics, Steven Spielberg Pediatric Research Center, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Diabetes 53:214-20. 2004
    ..3 mg/min). This haplotype-based genetic analysis provides compelling evidence that variation in the LPL gene plays a role in determining insulin resistance in this ethnic group with a high prevalence of the insulin resistance syndrome...
  15. ncbi request reprint SORCS1: a novel human type 2 diabetes susceptibility gene suggested by the mouse
    Mark O Goodarzi
    Cedars Sinai Medical Center, Division of Endocrinology, Diabetes, and Metabolism, 8700 Beverly Blvd, Becker B 131, Los Angeles, CA 90048, USA
    Diabetes 56:1922-9. 2007
    ..Thus, we sought to determine whether variation in the human SORCS1 gene was associated with diabetes-related traits...
  16. pmc Fasting insulin reflects heterogeneous physiological processes: role of insulin clearance
    Mark O Goodarzi
    Cedars Sinai Medical Center, Division of Endocrinology, Diabetes and Metabolism, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA
    Am J Physiol Endocrinol Metab 301:E402-8. 2011
    ..One of the most associated traits was insulin clearance, which has implications for studies that have used fasting insulin as a surrogate for insulin resistance...
  17. pmc Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Fertil Steril 95:1736-41.e1-11. 2011
    ..To evaluate association with polycystic ovary syndrome (PCOS) of 295 variants in 39 genes central to metabolic insulin signaling and glycogen synthase kinase 3β (GSK-3β) regulation, followed by replication efforts...
  18. ncbi request reprint Determination and use of haplotypes: ethnic comparison and association of the lipoprotein lipase gene and coronary artery disease in Mexican-Americans
    Mark O Goodarzi
    Division of Medical Genetics, Department of Medicine, Cedars Sinai Medical Center and UCLA, Los Angeles, California, USA
    Genet Med 5:322-7. 2003
    ..To illustrate an approach of deriving haplotypes for genetic association studies, using the lipoprotein lipase (LPL) gene and coronary artery disease...
  19. ncbi request reprint Management of deformational plagiocephaly: repositioning versus orthotic therapy
    John M Graham
    Medical Genetics Institute, Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Pediatr 146:258-62. 2005
    ..We compare positioning with orthotic therapy in 298 consecutive infants referred for correction of head asymmetry...
  20. pmc Preliminary evidence of glycogen synthase kinase 3 beta as a genetic determinant of polycystic ovary syndrome
    Mark O Goodarzi
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    Fertil Steril 87:1473-6. 2007
    ..In each racial group, we observed that a specific, although different, GSK3B haplotype was associated with increased frequency of PCOS, suggesting that GSK3beta contributes to the pathophysiology and inherited basis of PCOS...
  21. pmc Adiponectin, Insulin Sensitivity and Diabetic Retinopathy in Latinos With Type 2 Diabetes
    Jane Z Kuo
    Department of Ophthalmology J Z K, Shiley Eye Center, UC San Diego, La Jolla, California 92093 Pathway Genomics Corporation J Z K, San Diego, California 92121 Institute for Translational Genomics and Population Sciences X G, K R, Y H, J I R, Y D I C, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, California 90502 Department of Ophthalmology and Visual Sciences R K, B E K, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53726 Section of Diabetes and Metabolism P G, E I, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, California 90502 Division of Endocrinology, Diabetes, and Metabolism M O G, Cedars Sinai Medical Center, Los Angeles, California 90048
    J Clin Endocrinol Metab 100:3348-55. 2015
    ..We hypothesized that similar mechanisms could have a role in the development of diabetic retinopathy (DR), an important microvascular complication in Latinos with type 2 diabetes...
  22. pmc Insulin sensitivity and insulin clearance are heritable and have strong genetic correlation in Mexican Americans
    Mark O Goodarzi
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA Medical Genetics Research Institute, Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California, USA
    Obesity (Silver Spring) 22:1157-64. 2014
    ..The GUARDIAN (Genetics UndeRlying DIAbetes in HispaNics) consortium is described, along with heritability estimates and genetic and environmental correlations of insulin sensitivity and metabolic clearance rate of insulin (MCRI)...
  23. pmc Body adiposity index versus body mass index and other anthropometric traits as correlates of cardiometabolic risk factors
    Charlene T Lichtash
    Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 8:e65954. 2013
    ..We also compared BAI with BMI to determine which index is a better predictor of PBF...
  24. pmc Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    Dermot P B McGovern
    Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Hum Mol Genet 19:3468-76. 2010
    ..001). These findings strongly implicate this locus in CD susceptibility and highlight the role of the mucus layer in the development of CD...
  25. pmc Systemic soluble tumor necrosis factor receptors 1 and 2 are associated with severity of diabetic retinopathy in Hispanics
    Jane Z Kuo
    Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Ophthalmology 119:1041-6. 2012
    ..To investigate the associations of serum amyloid A (SAA) protein and soluble tumor necrosis factor receptors 1 and 2 (sTNF-R1 and sTNF-R2) with diabetic retinopathy (DR) in Hispanics...
  26. pmc Power of linkage analysis using traits generated from simulated longitudinal data of the Framingham Heart Study
    Dai Wang
    Division of Medical Genetics, Medical Genetics Birth Defect Center, Cedars Sinai Research Institute, Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, California 90048 USA
    BMC Genet 4:S28. 2003
    ..We found that using longitudinal traits based on multiple follow-ups may not be more powerful than using cross-sectional traits for genetic linkage analysis...
  27. ncbi request reprint Correlation of adrenocorticotropin steroid levels between women with polycystic ovary syndrome and their sisters
    Mark O Goodarzi
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Am J Obstet Gynecol 196:398.e1-5; discussion 398.e5-6. 2007
    ..The purpose of this study was to assess the sibling correlation of adrenocorticotropic hormone-stimulated steroid hormone levels between probands with polycystic ovary syndrome and their sisters...
  28. pmc Insulin Clearance Is Associated with Hepatic Lipase Activity and Lipid and Adiposity Traits in Mexican Americans
    Artak Labadzhyan
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 11:e0166263. 2016
    ..03). MCRI and apolipoprotein A-I exhibited a positive independent correlation (P = 0.035). These results generate a hypothesis that lipid and adiposity associated traits related to liver function may play a role in insulin clearance...
  29. pmc Evaluating gene x gene and gene x smoking interaction in rheumatoid arthritis using candidate genes in GAW15
    Ling Mei
    Department of Medical Genetics, Cedars Sinai Medical Center, 8700 Beverly Boulevard, 665 West Tower, Los Angeles, California 90048, USA
    BMC Proc 1:S17. 2007
    ..The strongest evidence of association was identified between the PTPN22 gene and RA status, which was consistently detected in single SNP association, gene x gene interaction and gene x smoking interaction analyses...
  30. pmc Heritability patterns in hand osteoarthritis: the role of osteophytes
    Mariko L Ishimori
    Division of Rheumatology, Cedars Sinai Medical Center, 8700 Beverly Blvd, B 131, Los Angeles, CA 90048, USA
    Arthritis Res Ther 12:R180. 2010
    ..The objective of the present study was to assess heritability of clinical and radiographic features of hand osteoarthritis (OA) in affected patients and their siblings...
  31. pmc Application of Bayesian classification with singular value decomposition method in genome-wide association studies
    Soonil Kwon
    Medical Genetics Institute, Cedars Sinai Medical Center, 8635 West Third Street, Los Angeles, CA 90048, USA
    BMC Proc 3:S9. 2009
    ..We have applied the BCSVD method here to the rheumatoid arthritis data distributed by GAW16 Problem 1 and demonstrated that the BCSVD method works well for analyzing GWAS data...
  32. pmc Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys
    Ning Xu
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 6:e27286. 2011
    ..This pilot study suggests that excess fetal androgen exposure in female nonhuman primates may predispose to PCOS via alteration of the epigenome, providing a novel avenue to understand PCOS in humans...
  33. pmc Identifying association under a previous linkage peak on chromosome 16 for body mass index using cross-sectional and longitudinal data of the Framingham Heart Study
    Xiaohui Li
    Medical Genetics Institute, Cedars Sinai Medical Center, 8635 West Third Street, Suite 1150, Los Angeles, California 90048 USA
    BMC Proc 3:S101. 2009
    ..4 Mbp, QTLD p = 0.0003).These results suggest the existence of genes/DNA variations in these regions that contribute to BMI variation...
  34. ncbi request reprint Variants in the 5alpha-reductase type 1 and type 2 genes are associated with polycystic ovary syndrome and the severity of hirsutism in affected women
    Mark O Goodarzi
    Department of Ob Gyn and Center for Androgen Related Disorders, Cedars Sinai Medical Center, 8635 West Third Street, Suite 160W, Los Angeles, CA 90048, USA
    J Clin Endocrinol Metab 91:4085-91. 2006
    ..Despite the importance of dihydrotestosterone in androgen action, polymorphisms in the genes for the two isoforms of 5alpha-reductase (SRD5A1 and SRD5A2) have not been evaluated as risk factors for polycystic ovary syndrome (PCOS)...
  35. doi request reprint TNFRSF1B Is Associated with ANCA in IBD
    Dalin Li
    Department of Medicine, F Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars Sinai Medical Center, Los Angeles, California Mount Sinai Hospital, Toronto, Ontario, Canada The Susan and Leonard Feinstein IBD Clinical Center, East New York, New York and Institute for Translational Genomics and Population Science, Los Angeles BioMedical Research Institute and Department of Pediatrics, Harbor UCLA Medical Center, Torrance, California
    Inflamm Bowel Dis 22:1346-52. 2016
    ..033). This finding indicates the functional role of identified TNFRSF1B variant in IBD serology and may be reflective of the underlying biological mechanisms that determine clinical expression and/or response to certain therapies. ..
  36. pmc Novel loci associated with increased risk of sudden cardiac death in the context of coronary artery disease
    Adriana Huertas-Vazquez
    The Heart Institute, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 8:e59905. 2013
    ..The objective of this study was to identify novel DNA variation associated with SCD in the context of coronary artery disease (CAD)...
  37. pmc Genetic predictors of medically refractory ulcerative colitis
    Talin Haritunians
    Medical Genetics Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Inflamm Bowel Dis 16:1830-40. 2010
    ..The aim of this study was to use a genome-wide association study (GWAS) in a well-characterized cohort of UC patients to identify genetic variation that contributes to MR-UC...
  38. pmc Application of an iterative Bayesian variable selection method in a genome-wide association study of rheumatoid arthritis
    Soonil Kwon
    Medical Genetics Institute, Cedars Sinai Medical Center, 8635 West Third Street, Suite 665, Los Angeles, California 90048, USA
    BMC Proc 1:S109. 2007
    ..When n > p, the iterative Bayesian variable selection performs better than stepwise variable selection does...
  39. doi request reprint Loss of the Y chromosome: an age-related or clonal phenomenon in acute myelogenous leukemia/myelodysplastic syndrome?
    Anna K Wong
    Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Arch Pathol Lab Med 132:1329-32. 2008
    ..A prior publication suggests that loss of the Y chromosome in more than 75% of cells may indicate a clonal phenomenon that could be a marker for hematologic disease...
  40. ncbi request reprint Deformational brachycephaly in supine-sleeping infants
    John M Graham
    Medical Genetics Institute, Ahmanson Department of Pediatrics, Steven Spielberg Pediatric Research Center, Burns and Allen Research Institute, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr 146:253-7. 2005
    ..Medical dictionaries and anthropologic sources define brachycephaly as a cranial index (CI = width divided by length x 100%) greater than 81%. We examine the impact of supine sleeping on CI and compare orthotic treatment with repositioning...
  41. ncbi request reprint Genetic heterogeneity in familial renal magnesium wasting
    Vitaly Kantorovich
    Burns and Allen Research Institute, University of Southern California, School of Medicine, Los Angeles, California 90033, USA
    J Clin Endocrinol Metab 87:612-7. 2002
    ..In conclusion, our data demonstrate locus heterogeneity for the phenotype of isolated renal Mg wasting with hypomagnesemia and suggest that hypomagnesemia, at least in this pedigree, may be associated with low bone mass...
  42. ncbi request reprint C-reactive protein gene polymorphism 1009A>G is associated with serum CRP levels in Chinese men: a TCVGHAGE study
    Wayne H H Sheu
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
    Clin Chim Acta 382:117-23. 2007
    ..Since the relation between CRP concentration and cardiovascular diseases occurs across ethnicities, we determined whether CRP gene variants affect fasting hs-CRP concentrations in a cohort of Chinese men...
  43. ncbi request reprint Associations of adiponectin with body fat distribution and insulin sensitivity in nondiabetic Hispanics and African-Americans
    Anthony J G Hanley
    Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada M5S 3E2
    J Clin Endocrinol Metab 92:2665-71. 2007
    ....
  44. doi request reprint Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment
    Ronald M Krauss
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Circulation 117:1537-44. 2008
    ..We hypothesized that single nucleotide polymorphisms in the gene encoding HMGCR, a rate-limiting enzyme in cholesterol synthesis and the direct enzymatic target of statins, contribute to variation in statin response...
  45. ncbi request reprint Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND)
    Jeffrey R Schelling
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Wolstein Research Building, Rm 1300, 10900 Euclid Ave, Cleveland, OH 44106 7281, USA
    Diabetes 57:235-43. 2008
    ..Glomerular filtration rate (GFR), which characterizes diabetic nephropathy, was employed as a quantitative trait in a preliminary whole-genome scan...