Philip K Frykman

Summary

Affiliation: Cedars-Sinai Medical Center
Country: USA

Publications

  1. pmc Evaluation of a video telescopic operating microscope (VITOM) for pediatric surgery and urology: a preliminary report
    Philip K Frykman
    Division of Pediatric Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Laparoendosc Adv Surg Tech A 23:639-43. 2013
  2. pmc Hirschsprung-associated enterocolitis: prevention and therapy
    Philip K Frykman
    Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Semin Pediatr Surg 21:328-35. 2012
  3. doi request reprint Experience with a new 3-mm laparoscope in complex neonatal minimally invasive surgery: a preliminary report
    Philip K Frykman
    Division of Pediatric Surgery, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Laparoendosc Adv Surg Tech A 18:439-42. 2008
  4. pmc Murine model of Hirschsprung-associated enterocolitis II: Surgical correction of aganglionosis does not eliminate enterocolitis
    Lifu Zhao
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 45:206-11; discussion 211-2. 2010
  5. pmc Murine model of Hirschsprung-associated enterocolitis. I: phenotypic characterization with development of a histopathologic grading system
    Zhi Cheng
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 45:475-82. 2010
  6. pmc Splenic lymphopenia in the endothelin receptor B-null mouse: implications for Hirschsprung associated enterocolitis
    Zhi Cheng
    The Pediatric Surgery Laboratory, Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, 8635 W Third Street Suite 650 W, Los Angeles, CA 90048, USA
    Pediatr Surg Int 27:145-50. 2011
  7. pmc Distinct phenotypes of children with perianal perforating Crohn's disease
    Scott S Short
    Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 48:1301-5. 2013
  8. doi request reprint Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis
    Farokh R Demehri
    Division of Pediatric Surgery, C S Mott Children s Hospital, University of Michigan, Ann Arbor, MI, USA
    J Pediatr Surg 51:81-6. 2016
  9. pmc A novel corrective pullthrough surgery in a mouse model of Hirschsprung's disease
    Lifu Zhao
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 44:759-66. 2009
  10. pmc Enterocolitis causes profound lymphoid depletion in endothelin receptor B- and endothelin 3-null mouse models of Hirschsprung-associated enterocolitis
    Philip K Frykman
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Eur J Immunol 45:807-17. 2015

Collaborators

Detail Information

Publications18

  1. pmc Evaluation of a video telescopic operating microscope (VITOM) for pediatric surgery and urology: a preliminary report
    Philip K Frykman
    Division of Pediatric Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Laparoendosc Adv Surg Tech A 23:639-43. 2013
    ..This study was designed to evaluate VITOM as a potential substitute for loupes in complex open pediatric procedures and to explore VITOM as an effective intraoperative teaching modality for open surgery...
  2. pmc Hirschsprung-associated enterocolitis: prevention and therapy
    Philip K Frykman
    Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Semin Pediatr Surg 21:328-35. 2012
    ..The chapter also details approaches to diagnose Hirschsprung-associated enterocolitis as well as to exclude other etiologies...
  3. doi request reprint Experience with a new 3-mm laparoscope in complex neonatal minimally invasive surgery: a preliminary report
    Philip K Frykman
    Division of Pediatric Surgery, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Laparoendosc Adv Surg Tech A 18:439-42. 2008
    ..Our experience with the new 3-mm telescope is superb for the demands of complex neonatal endosurgical procedures...
  4. pmc Murine model of Hirschsprung-associated enterocolitis II: Surgical correction of aganglionosis does not eliminate enterocolitis
    Lifu Zhao
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 45:206-11; discussion 211-2. 2010
    ..The genetic and molecular mechanisms underlying these disorders are largely unknown...
  5. pmc Murine model of Hirschsprung-associated enterocolitis. I: phenotypic characterization with development of a histopathologic grading system
    Zhi Cheng
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 45:475-82. 2010
    ..The aim of the study was to characterize enterocolitis in the Ednrb-null (Ednrb-/-) mouse with aganglionosis of the colon and to develop and validate a semiquantitative histopathologic grading system to assess enterocolitis...
  6. pmc Splenic lymphopenia in the endothelin receptor B-null mouse: implications for Hirschsprung associated enterocolitis
    Zhi Cheng
    The Pediatric Surgery Laboratory, Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, 8635 W Third Street Suite 650 W, Los Angeles, CA 90048, USA
    Pediatr Surg Int 27:145-50. 2011
    ..The aim of the study was to describe and characterize a novel small spleen phenotype with splenic lymphopenia in the Ednrb-null (Ednrb-/-) mouse with aganglionosis known to also develop enterocolitis...
  7. pmc Distinct phenotypes of children with perianal perforating Crohn's disease
    Scott S Short
    Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 48:1301-5. 2013
    ..It is unknown whether children who present with PF at the time of diagnosis have a different course than those that develop PF while on therapy...
  8. doi request reprint Altered fecal short chain fatty acid composition in children with a history of Hirschsprung-associated enterocolitis
    Farokh R Demehri
    Division of Pediatric Surgery, C S Mott Children s Hospital, University of Michigan, Ann Arbor, MI, USA
    J Pediatr Surg 51:81-6. 2016
    ..As SCFAs play a critical role in colonic mucosal preservation, we hypothesized that fecal SCFA composition is altered in children with HAEC...
  9. pmc A novel corrective pullthrough surgery in a mouse model of Hirschsprung's disease
    Lifu Zhao
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 44:759-66. 2009
    ..The study aimed to develop a mouse model of post-pullthrough Hirschsprung's disease that will allow investigation of mechanisms that cause postoperative complications...
  10. pmc Enterocolitis causes profound lymphoid depletion in endothelin receptor B- and endothelin 3-null mouse models of Hirschsprung-associated enterocolitis
    Philip K Frykman
    Division of Pediatric Surgery and The Pediatric Surgery Laboratory, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Eur J Immunol 45:807-17. 2015
    ....
  11. pmc Characterization of Bacterial and Fungal Microbiome in Children with Hirschsprung Disease with and without a History of Enterocolitis: A Multicenter Study
    Philip K Frykman
    Division of Pediatric Surgery, Departments of Surgery, Cedars Sinai Medical Center, Los Angeles, California, United States of America Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California, United States of America
    PLoS ONE 10:e0124172. 2015
    ..These findings suggest a dysbiosis in the gut microbial ecosystem of HAEC patients, such that there may be dominance of fungi and bacteria predisposing patients to development of HAEC. ..
  12. pmc Late onset of necrotizing enterocolitis in the full-term infant is associated with increased mortality: results from a two-center analysis
    Scott S Short
    Division of Pediatric Surgery, Children s Hospital Los Angeles, and the Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Pediatr Surg 49:950-3. 2014
    ..The effect of timing of onset of necrotizing enterocolitis (NEC) on outcomes has not been determined for the full-term infant. In this study we aimed to characterize the full-term NEC population and to evaluate onset of NEC...
  13. ncbi request reprint A Study of VITOM in Pediatric Surgery and Urology: Evaluation of Technology Acceptance and Usability by Operating Team and Surgeon Musculoskeletal Discomfort
    Philip K Frykman
    1 Division of Pediatric Surgery, Cedars Sinai Medical Center, Los Angeles, California
    J Laparoendosc Adv Surg Tech A . 2016
    ..We studied operating team acceptability of Video Telescopic Monitor (VITOM®) exoscope by exploring the ease of use of the device in two centers. We also assessed factors affecting surgeon musculoskeletal discomfort...
  14. pmc Is routine preoperative screening echocardiogram indicated in all children with congenital duodenal obstruction?
    Scott S Short
    Division of Pediatric Surgery, Children s Hospital Los Angeles, 4650 Sunset Blvd MS 100, Los Angeles, CA, 90027, USA
    Pediatr Surg Int 30:609-14. 2014
    ..We aimed to identify and characterize CHD in children with DO to determine if appropriately selected patients could forego preoperative echocardiogram...
  15. doi request reprint Laparoscopic common bile duct exploration in children is associated with decreased cost and length of stay: results of a two-center analysis
    Scott S Short
    Cedars Sinai Medical Center, Los Angeles, CA, USA
    J Pediatr Surg 48:215-20. 2013
    ....
  16. doi request reprint Duodenal necrosis secondary to a closed-loop bowel obstruction with novel reconstruction
    Massimo Arcerito
    Department of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    J Pediatr Surg 47:394-6. 2012
    ..This case highlights an alternative strategy for reestablishing gastrointestinal and biliopancreatic continuity while avoiding more complex procedures...
  17. pmc Colorectal infantile myofibromatosis: an unusual cause of rectal prolapse and sigmoid colo-colonic intussusception: a case report
    Deepti Dhall
    Department of Pathology and Laboratory Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Cases J 1:397. 2008
    ..Infantile myofibromatosis is a rare mesenchymal disorder of infancy that can extensively involve the viscera including the gastrointestinal tract...
  18. doi request reprint Spectral imaging for precise surgical intervention in Hirschsprung's disease
    Philip K Frykman
    Division of Pediatric Surgery, Department of Surgery, Cedars Sinai Medical Center, Los Angeles CA 90048, USA
    J Biophotonics 1:97-103. 2008
    ..These studies showed translational proof of concept that spectral imaging could be used during operations, in real time, to help surgeons precisely distinguish normal from abnormal tissue without requiring traditional biopsy...