Christopher G Wilson

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Adenosine A2A receptors interact with GABAergic pathways to modulate respiration in neonatal piglets
    Christopher G Wilson
    Department of Pediatrics, Case Western Reserve University School of Medicine, Division of Neonatology, Suite 3100, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 141:201-11. 2004
  2. pmc Developmental changes in brainstem neurons regulating lower airway caliber
    Amitai Z Kohn
    Department of Pediatrics, Case Western Reserve University, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    Pediatr Res 65:509-13. 2009
  3. pmc Vagal afferents modulate cytokine-mediated respiratory control at the neonatal medulla oblongata
    Kannan V Balan
    Department of Pediatrics, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 178:458-64. 2011
  4. pmc Effect of intermittent hypercapnia on respiratory control in rat pups
    Justin A Steggerda
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Neonatology 97:117-23. 2010
  5. ncbi request reprint Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats
    Catherine A Mayer
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, Ohio, USA
    J Appl Physiol (1985) 100:91-7. 2006
  6. pmc Intrapulmonary lipopolysaccharide exposure upregulates cytokine expression in the neonatal brainstem
    Kannan V Balan
    Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106 6010, USA
    Acta Paediatr 101:466-71. 2012
  7. ncbi request reprint Modeling of sleep-induced changes in airway function: implication for nocturnal worsening of bronchial asthma
    Musa A Haxhiu
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Adv Exp Med Biol 605:469-74. 2008
  8. pmc Airway inflammation and central respiratory control: results from in vivo and in vitro neonatal rat
    Kenneth Gresham
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, United States
    Respir Physiol Neurobiol 178:414-21. 2011
  9. ncbi request reprint Role of inhibitory neurotransmitter interactions in the pathogenesis of neonatal apnea: implications for management
    Richard J Martin
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, OH 44106 6010, USA
    Semin Perinatol 28:273-8. 2004
  10. pmc Lung inflammation induces IL-1β expression in hypoglossal neurons in rat brainstem
    Anjum Jafri
    Department of Pediatrics, Division of Neonatology, Rainbow Babies and Children s Hospital, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 188:21-8. 2013

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Adenosine A2A receptors interact with GABAergic pathways to modulate respiration in neonatal piglets
    Christopher G Wilson
    Department of Pediatrics, Case Western Reserve University School of Medicine, Division of Neonatology, Suite 3100, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 141:201-11. 2004
    ..These findings offer new insight into the mechanism whereby xanthine therapy diminishes apnea of prematurity...
  2. pmc Developmental changes in brainstem neurons regulating lower airway caliber
    Amitai Z Kohn
    Department of Pediatrics, Case Western Reserve University, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106, USA
    Pediatr Res 65:509-13. 2009
    ..We speculate that exposure to injurious agents in early postnatal life may inhibit natural remodeling and thereby enhance later vulnerability to airway hyperreactivity...
  3. pmc Vagal afferents modulate cytokine-mediated respiratory control at the neonatal medulla oblongata
    Kannan V Balan
    Department of Pediatrics, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 178:458-64. 2011
    ....
  4. pmc Effect of intermittent hypercapnia on respiratory control in rat pups
    Justin A Steggerda
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Neonatology 97:117-23. 2010
    ..05). We speculate that prior hypercapnic exposure may increase peripheral chemoreceptor response to subsequent hypoxic exposures and result in perturbed neonatal respiratory control...
  5. ncbi request reprint Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats
    Catherine A Mayer
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, Ohio, USA
    J Appl Physiol (1985) 100:91-7. 2006
    ..These findings demonstrate an important mechanism by which xanthine therapy alleviates apnea of prematurity...
  6. pmc Intrapulmonary lipopolysaccharide exposure upregulates cytokine expression in the neonatal brainstem
    Kannan V Balan
    Rainbow Babies and Children s Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106 6010, USA
    Acta Paediatr 101:466-71. 2012
    ..LPS increased brainstem IL-1β and vagotomy blunted this response. There was an attenuated ventilatory response to hypoxia and increased brainstem IL-1β expression after LPS...
  7. ncbi request reprint Modeling of sleep-induced changes in airway function: implication for nocturnal worsening of bronchial asthma
    Musa A Haxhiu
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio 44106, USA
    Adv Exp Med Biol 605:469-74. 2008
    ....
  8. pmc Airway inflammation and central respiratory control: results from in vivo and in vitro neonatal rat
    Kenneth Gresham
    Department of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, United States
    Respir Physiol Neurobiol 178:414-21. 2011
    ....
  9. ncbi request reprint Role of inhibitory neurotransmitter interactions in the pathogenesis of neonatal apnea: implications for management
    Richard J Martin
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, OH 44106 6010, USA
    Semin Perinatol 28:273-8. 2004
  10. pmc Lung inflammation induces IL-1β expression in hypoglossal neurons in rat brainstem
    Anjum Jafri
    Department of Pediatrics, Division of Neonatology, Rainbow Babies and Children s Hospital, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 188:21-8. 2013
    ..LPS-induced brainstem expression of neuronal IL-1β mRNA and protein may have implications for our understanding of the vulnerability of neonatal respiratory control in response to a peripheral proinflammatory stimulus...
  11. doi request reprint Apnea of prematurity
    Richard J Martin
    Department of Pediatrics, Case Western Reserve University, Cleveland, Ohio, USA
    Compr Physiol 2:2923-31. 2012
    ....
  12. pmc Mutation in the myelin proteolipid protein gene alters BK and SK channel function in the caudal medulla
    Catherine A Mayer
    Department of Pediatrics, Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, United States
    Respir Physiol Neurobiol 169:303-14. 2009
    ..These results provide evidence that Plp mutation specifically alters neuronal excitability through calcium-dependent potassium channels in nTS...
  13. ncbi request reprint Effect of supplemental oxygen on reinitiation of breathing after neonatal resuscitation in rat pups
    G Bradley Bookatz
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Cleveland, Ohio 44106 6010, USA
    Pediatr Res 61:698-702. 2007
    ..Our findings indicate that even modest hyperoxic resuscitation will result in a delayed onset of respiration compared with normoxic gas, via a mechanism that may involve both hyperoxemic and hypocapnic inhibition of chemoreceptors...
  14. pmc BACE1 deficiency causes altered neuronal activity and neurodegeneration
    Xiangyou Hu
    Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Neurosci 30:8819-29. 2010
    ..The knowledge from this study is crucial for the development of BACE1 inhibitors for Alzheimer's therapy and to the applicative study of epilepsy...
  15. pmc Arrest of 5HT neuron differentiation delays respiratory maturation and impairs neonatal homeostatic responses to environmental challenges
    Jeffery T Erickson
    Case Western Reserve University School of Medicine, Department of Neurosciences, 10900 Euclid Avenue, Cleveland, OH 44106, USA
    Respir Physiol Neurobiol 159:85-101. 2007
    ....
  16. pmc The relationship between patterns of intermittent hypoxia and retinopathy of prematurity in preterm infants
    Juliann M Di Fiore
    Department of Pediatrics, Rainbow Babies and Children s Hospital, Case Western Reserve University, Cleveland, Ohio, USA
    Pediatr Res 72:606-12. 2012
    ..Animal models suggest that patterns of IH events may play a role in ROP severity as well. We hypothesize that specific IH event patterns are associated with ROP in preterm infants...
  17. doi request reprint Drive latencies in hypoglossal motoneurons indicate developmental change in the brainstem respiratory network
    Christopher Fietkiewicz
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH 44106, USA
    J Neural Eng 8:065011. 2011
    ..Through simulations, we show the effects on the preBötC of different network characteristics such as clustering and common inputs...
  18. ncbi request reprint Allergic lung inflammation affects central noradrenergic control of cholinergic outflow to the airways in ferrets
    Christopher G Wilson
    Department of Pediatrics, Case Western Reserve University, School of Medicine, Cleveland, OH 44106 6010, USA
    J Appl Physiol (1985) 103:2095-104. 2007
    ....
  19. pmc Cardio-ventilatory coupling in young healthy resting subjects
    Lee Friedman
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA
    J Appl Physiol (1985) 112:1248-57. 2012
    ..CVC for the R-to-I interval was unrelated to two separate measures of respiratory sinus arrhythmia (RSA), suggesting that these two forms of coupling (CVC and RSA) are independent...
  20. pmc Periodicity, mixed-mode oscillations, and quasiperiodicity in a rhythm-generating neural network
    Christopher A Del Negro
    Cellular and Systems Neurobiology Section, Laboratory of Neural Control, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA
    Biophys J 82:206-14. 2002
    ....
  21. ncbi request reprint A GABAergic inhibitory microcircuit controlling cholinergic outflow to the airways
    Constance T Moore
    Deparment of Physiology and Biophysics, Howard University College of Medicine, Washington, DC 20059, USA
    J Appl Physiol 96:260-70. 2004
    ..We conclude that a tonically active monosynaptic GABAergic circuit utilizing symmetric synapses regulates the discharge of AVPNs...
  22. ncbi request reprint Respiratory network complexity in neonatal rat in vivo and in vitro
    Hui Jing Yu
    State University of New York at Stony Brook, Department of Physiology and Biophysics, USA
    Adv Exp Med Biol 605:393-8. 2008
    ..We suggest that additional studies be conducted to identify the precise mechanisms responsible for the differences in central inspiratory neural network complexity between these two neonatal rat preparations...
  23. ncbi request reprint Brain stem excitatory and inhibitory signaling pathways regulating bronchoconstrictive responses
    Musa A Haxhiu
    Dept of Physiology and Biophysics, Howard University College of Medicine, 520 W St NW, Washington, DC 20059, USA
    J Appl Physiol (1985) 98:1961-82. 2005
    ..Hence a better understanding of these normal and altered central neural circuits and mechanisms could potentially improve the design of therapeutic interventions and the treatment of airway obstructive diseases...
  24. ncbi request reprint An astrocyte toxin influences the pattern of breathing and the ventilatory response to hypercapnia in neonatal rats
    John K Young
    Department of Anatomy, Howard University College of Medicine, Washington, DC 20059, USA
    Respir Physiol Neurobiol 147:19-30. 2005
    ....
  25. ncbi request reprint Sleep networks and the anatomic and physiologic connections with respiratory control
    Musa A Haxhiu
    Specialized Neuroscience Research Program, Department of Physiology and Biophysics, Howard University College of Medicine, 520 W St N W, Washington, DC 20059, USA
    Front Biosci 8:d946-62. 2003
    ..Pharmacological corrections of alterations of these transmitter specific converging systems might be an avenue for treatment of sleep related airway disorders such as sleep apnea and worsening of asthma...
  26. doi request reprint Functional imaging, spatial reconstruction, and biophysical analysis of a respiratory motor circuit isolated in vitro
    Hidehiko Koizumi
    Cellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Neurosci 28:2353-65. 2008
    ....