John L Johnson

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. ncbi request reprint Impact of human immunodeficiency virus type-1 infection on the initial bacteriologic and radiographic manifestations of pulmonary tuberculosis in Uganda. Makerere University-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Int J Tuberc Lung Dis 2:397-404. 1998
  2. ncbi request reprint Effect of Mycobacterium vaccae (SRL172) immunotherapy on radiographic healing in tuberculosis
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106 5083, USA
    Int J Tuberc Lung Dis 8:1348-54. 2004
  3. ncbi request reprint Randomized trial of adjunctive interleukin-2 in adults with pulmonary tuberculosis
    John L Johnson
    Division of Infectious Diseases, Department of Medicine, Case Western Reserve University, Room E 202, Tuberculosis Research Unit, 10900 Euclid Avenue, Cleveland, OH 44106 4984, USA
    Am J Respir Crit Care Med 168:185-91. 2003
  4. ncbi request reprint Aspiration pneumonia. Recognizing and managing a potentially growing disorder
    John L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Room E 202, Tuberculosis Research Unit, 10900 Euclid Ave, Cleveland, OH 44106 4984, USA
    Postgrad Med 113:99-102, 105-6, 111-2. 2003
  5. ncbi request reprint Manifestations of hemoptysis. How to manage minor, moderate, and massive bleeding
    John L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Room E 202, Tuberculosis Research Unit, 10900 Euclid Ave, Cleveland, OH 44106 4984, USA
    Postgrad Med 112:101-6, 108-9, 113. 2002
  6. ncbi request reprint Slowly resolving and nonresolving pneumonia. Questions to ask when response is delayed
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4984, USA
    Postgrad Med 108:115-22; quiz 13. 2000
  7. pmc Efficacy of an unsupervised 8-month rifampicin-containing regimen for the treatment of pulmonary tuberculosis in HIV-infected adults. Uganda-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Int J Tuberc Lung Dis 4:1032-40. 2000
  8. ncbi request reprint Instability of tuberculin and Candida skin test reactivity in HIV-infected Ugandans. The Uganda-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA
    Am J Respir Crit Care Med 158:1790-6. 1998
  9. ncbi request reprint Adult tuberculosis overview: African versus Western perspectives
    J L Johnson
    Department of Medicine, Case Western Reserve University and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Curr Opin Pulm Med 6:180-6. 2000
  10. ncbi request reprint Pleural effusions in cardiovascular disease. Pearls for correlating the evidence with the cause
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106 4984, USA
    Postgrad Med 107:95-101; quiz 257. 2000

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Impact of human immunodeficiency virus type-1 infection on the initial bacteriologic and radiographic manifestations of pulmonary tuberculosis in Uganda. Makerere University-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Int J Tuberc Lung Dis 2:397-404. 1998
    ..TB Treatment Centre, Kampala, Uganda...
  2. ncbi request reprint Effect of Mycobacterium vaccae (SRL172) immunotherapy on radiographic healing in tuberculosis
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio 44106 5083, USA
    Int J Tuberc Lung Dis 8:1348-54. 2004
    ....
  3. ncbi request reprint Randomized trial of adjunctive interleukin-2 in adults with pulmonary tuberculosis
    John L Johnson
    Division of Infectious Diseases, Department of Medicine, Case Western Reserve University, Room E 202, Tuberculosis Research Unit, 10900 Euclid Avenue, Cleveland, OH 44106 4984, USA
    Am J Respir Crit Care Med 168:185-91. 2003
    ..One patient in each arm relapsed. IL-2 did not enhance bacillary clearance or improvement in symptoms in human immunodeficiency virus-seronegative adults with drug-susceptible tuberculosis...
  4. ncbi request reprint Aspiration pneumonia. Recognizing and managing a potentially growing disorder
    John L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Room E 202, Tuberculosis Research Unit, 10900 Euclid Ave, Cleveland, OH 44106 4984, USA
    Postgrad Med 113:99-102, 105-6, 111-2. 2003
    ....
  5. ncbi request reprint Manifestations of hemoptysis. How to manage minor, moderate, and massive bleeding
    John L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Room E 202, Tuberculosis Research Unit, 10900 Euclid Ave, Cleveland, OH 44106 4984, USA
    Postgrad Med 112:101-6, 108-9, 113. 2002
    ..Massive hemoptysis may recur without warning. Prompt workup and treatment are required for all patients...
  6. ncbi request reprint Slowly resolving and nonresolving pneumonia. Questions to ask when response is delayed
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 4984, USA
    Postgrad Med 108:115-22; quiz 13. 2000
    ..He also discusses reasonable timing of further studies and the usefulness of radiography and fiberoptic bronchoscopy...
  7. pmc Efficacy of an unsupervised 8-month rifampicin-containing regimen for the treatment of pulmonary tuberculosis in HIV-infected adults. Uganda-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Int J Tuberc Lung Dis 4:1032-40. 2000
    ..National Tuberculosis Treatment Centre, Mulago Hospital, Kampala, Uganda...
  8. ncbi request reprint Instability of tuberculin and Candida skin test reactivity in HIV-infected Ugandans. The Uganda-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Division of Infectious Diseases, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, Ohio, USA
    Am J Respir Crit Care Med 158:1790-6. 1998
    ....
  9. ncbi request reprint Adult tuberculosis overview: African versus Western perspectives
    J L Johnson
    Department of Medicine, Case Western Reserve University and University Hospitals of Cleveland, Ohio 44106 4984, USA
    Curr Opin Pulm Med 6:180-6. 2000
    ..The purpose of this review is to provide a synopsis of recent developments in these areas and to serve as a reference source for interested readers...
  10. ncbi request reprint Pleural effusions in cardiovascular disease. Pearls for correlating the evidence with the cause
    J L Johnson
    Division of Infectious Diseases, Case Western Reserve University School of Medicine, Cleveland, OH 44106 4984, USA
    Postgrad Med 107:95-101; quiz 257. 2000
    ..Prompt diagnostic thoracentesis is indicated whenever atypical features are present and other diagnoses are under consideration...
  11. ncbi request reprint Randomized controlled trial of Mycobacterium vaccae immunotherapy in non-human immunodeficiency virus-infected ugandan adults with newly diagnosed pulmonary tuberculosis. The Uganda-Case Western Reserve University Research Collaboration
    J L Johnson
    Department of Medicine, Division of Infectious Diseases, Case Western Reserve University, Tuberculosis Research Unit, Cleveland, OH 44106 4984, USA
    J Infect Dis 181:1304-12. 2000
    ..04) after initiation of tuberculosis treatment. These data provide evidence of an early increase in sputum culture conversion and greater radiographic improvement among patients who received M. vaccae. Further studies are warranted...
  12. pmc Shortening treatment in adults with noncavitary tuberculosis and 2-month culture conversion
    John L Johnson
    Tuberculosis Research Unit, Department of Medicine, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, Ohio 44106 5083, USA
    Am J Respir Crit Care Med 180:558-63. 2009
    ..Cavitary disease and delayed culture conversion have been associated with relapse. Combining patient characteristics and measures of bacteriologic response might allow treatment shortening with current drugs in some patients...
  13. ncbi request reprint Mechanisms of apoptosis of T-cells in human tuberculosis
    Christina S Hirsch
    Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106 4984, USA
    J Clin Immunol 25:353-64. 2005
    ..001). These findings may indicate that, during TB, predisposition of CD4 T-cells to apoptosis may involve both low expression of Bcl-2, and excessive expression of TGF-beta TNF-alpha and FasL...
  14. ncbi request reprint A study of the safety, immunology, virology, and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis
    Robert S Wallis
    Department of Medicine, Case Western Reserve University, Cleveland, OH, USA
    AIDS 18:257-64. 2004
    ..This phase 1 study examined the safety, microbiology, immunology, and virology of TNF blockade using etanercept (soluble TNF receptor, Enbrel) during the initial treatment of HIV-associated tuberculosis...
  15. pmc Effects of tuberculosis, race, and human gene SLCO1B1 polymorphisms on rifampin concentrations
    Marc Weiner
    Division of Infectious Diseases, University of Texas Health Science Center San Antonio and South Texas Veterans Health Care System, San Antonio, Texas 78229 4404, USA
    Antimicrob Agents Chemother 54:4192-200. 2010
    ....
  16. pmc Weight gain and response to treatment for multidrug-resistant tuberculosis
    Ma Tarcela Gler
    Tropical Disease Foundation, Makati City, Philippines Division of TB Elimination, Centers for Disease Control and Prevention, Atlanta, Georgia Tuberculosis Research Unit, Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio
    Am J Trop Med Hyg 89:943-9. 2013
    ..1; 95% confidence interval [CI], 1.05 to 4.4). Baseline weight and degree of weight change during the first 6 months of treatment can help identify persons who are more likely to have poor outcomes and require other interventions...
  17. pmc Persistent replication of human immunodeficiency virus type 1 despite treatment of pulmonary tuberculosis in dually infected subjects
    Harriet Mayanja Kizza
    Case Western Reserve University, Department of Medicine, Cleveland Clinic Foundation, Cleveland, OH 44106 4984, USA
    Clin Diagn Lab Immunol 12:1298-304. 2005
    ..Concurrent institution of highly active antiretroviral treatment needs to be evaluated in patients dually infected with pulmonary TB and HIV-1...
  18. ncbi request reprint Whole blood bactericidal activity during treatment of pulmonary tuberculosis
    Robert S Wallis
    Department of Medicine, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103, USA
    J Infect Dis 187:270-8. 2003
    ..018), both of which are indicative of prognosis. These findings indicate that measurement of WBA may have a role in assessing the sterilizing activity of new anti-TB drugs...
  19. pmc Evaluation of time to detection of Mycobacterium tuberculosis in broth culture as a determinant for end points in treatment trials
    Marc Weiner
    Department of Medicine, University of Texas Health Science Center San Antonio, VAMC, Division of Infectious Diseases 111, 7400 Merton Minter Blvd, San Antonio TX 78229 4404, USA
    J Clin Microbiol 48:4370-6. 2010
    ..Time to detection in an analysis-of-covariance model was associated with lung cavities, less intensive treatment, and differences in the bactericidal effects of treatment regimens...
  20. pmc Human immunodeficiency virus type 1 (HIV-1) quasispecies at the sites of Mycobacterium tuberculosis infection contribute to systemic HIV-1 heterogeneity
    Kalonji R Collins
    Division of Infectious Diseases, Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Virol 76:1697-706. 2002
    ..Collectively, these findings suggest that HIV-1 quasispecies in the M. tuberculosis-infected pleural space may leak into the systemic circulation and lead to increased systemic HIV-1 heterogeneity during TB...
  21. pmc Effect of improving the quality of radiographic interpretation on the ability to predict pulmonary tuberculosis relapse
    Jason E Stout
    Division of Infectious Diseases and International Health, Department of Medicine, 3306 Duke University Medical Center, Durham, NC 27710, USA
    Acad Radiol 17:157-62. 2010
    ....
  22. pmc Comparison of MGIT and Myco/F lytic liquid-based blood culture systems for recovery of Mycobacterium tuberculosis from pleural fluid
    Elizabeth Harausz
    Division of Infectious Disease and HIV Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    J Clin Microbiol 53:1391-4. 2015
    ..The time to positivity is shorter in the MGIT system (12.7 versus 20.7 days, respectively; P=0.007). The Myco/F lytic culture system may be an alternative to the MGIT system for diagnosing pleural tuberculosis...
  23. ncbi request reprint Prosthetic joint infection: when to suspect it, how to manage it
    Lucileia Teixeira
    Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Geriatrics 62:18-22. 2007
    ..Successful outcomes require expert orthopedic surgical management and prolonged antibiotic therapy. Treatment should be individualized according to the specific pathogen and clinical circumstances...
  24. ncbi request reprint Osteomyelitis in diabetic foot ulcers. Prompt diagnosis can avert amputation
    Matthew K Schinabeck
    Division of Infectious Diseases, University Hospitals of Cleveland, OH, USA
    Postgrad Med 118:11-5. 2005
    ..Here, Drs Schinabeck and Johnson review the clinical, laboratory, and radiologic findings critical to making an early diagnosis of osteomyelitis...
  25. doi request reprint Effect of Isoniazid Therapy for Latent TB Infection on QuantiFERON-TB Gold In-Tube Responses in Adults With Positive Tuberculin Skin Test Results in a High TB Incidence Area
    John L Johnson
    Tuberculosis Research Unit, Department of Medicine, Case Western Reserve University School of Medicine, and University Hospitals Case Medical Center, Cleveland, OH Electronic address
    Chest 145:612-617. 2014
    ....
  26. ncbi request reprint Capacity building for the clinical investigation of AIDS malignancy in East Africa
    Jackson Orem
    Fogarty AIDS International Training and Research Program, Case School of Medicine, Case Western Reserve University, Cleveland, OH, USA
    Cancer Detect Prev 29:133-45. 2005
    ..To build capacity in the resource-poor setting to support the clinical investigation and treatment of AIDS-related malignancies in a region of the world hardest hit by the AIDS pandemic...
  27. pmc Sputum cytokine levels in patients with pulmonary tuberculosis as early markers of mycobacterial clearance
    Rodrigo Ribeiro-Rodrigues
    Universidade Federal do Espirito Santo, Núcleo Doenças Infecciosas, Vitoria, ES, Brazil
    Clin Diagn Lab Immunol 9:818-23. 2002
    ..These data indicate that sputum cytokines correlate with disease activity during active TB of the lung and may serve as potential early markers for sputum conversion and response to anti-TB therapy...
  28. ncbi request reprint Recent advances in the diagnosis and management of tuberculosis
    Jennifer J Furin
    Division of Social Medicine and Health Inequalities, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Curr Opin Pulm Med 11:189-94. 2005
    ..Tuberculosis (TB) remains one of the leading infectious killers of adults in the world today. This paper will review recent advances and understanding in the epidemiology, diagnosis, and management of TB...
  29. pmc Population pharmacokinetics of levofloxacin, gatifloxacin, and moxifloxacin in adults with pulmonary tuberculosis
    Charles A Peloquin
    Infectious Disease Pharmacokinetics Laboratory, National Jewish Medical and Research Center, Denver, CO 80206, USA
    Antimicrob Agents Chemother 52:852-7. 2008
    ..All three quinolones showed favorable pharmacokinetic and pharmacodynamic indices, with the most favorable results in this population being seen with levofloxacin at the comparative doses used...
  30. ncbi request reprint Moxifloxacin versus ethambutol in the first 2 months of treatment for pulmonary tuberculosis
    William J Burman
    Denver Public Health and the Department of Medicine, University of Colorado Health Sciences National Jewish Medical and Research Center, Denver, Colorado, USA
    Am J Respir Crit Care Med 174:331-8. 2006
    ..Moxifloxacin has promising preclinical activity against Mycobacterium tuberculosis, but has not been evaluated in multidrug treatment of tuberculosis in humans...
  31. pmc Cavitary disease and quantitative sputum bacillary load in cases of pulmonary tuberculosis
    Moises Palaci
    Núcleo de Doenças Infecciosas Centro de Ciências da Saúde, Universidade Federal do Espirito Santo, Av Marechal Campos, 1468 Maruipe, Vitoria, Brazil
    J Clin Microbiol 45:4064-6. 2007
    ..Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease...
  32. ncbi request reprint A randomized, double-blind, placebo-controlled trial of the use of prednisolone as an adjunct to treatment in HIV-1-associated pleural tuberculosis
    Alison M Elliott
    Uganda Virus Research Institute, Entebbe
    J Infect Dis 190:869-78. 2004
    ..We examined the effect that prednisolone has on survival in HIV-1-associated pleural tuberculosis...
  33. ncbi request reprint Rifampicin-containing regimens for the treatment of latent tuberculosis infection also prevented diarrheal illnesses in HIV-infected Ugandan adults
    John L Johnson
    AIDS 18:706-8. 2004
  34. ncbi request reprint Whither Mycobacterium vaccae--encore
    P Bernard Fourie
    Medical Research Council, Pretoria, South Africa
    Lancet 360:1032-3. 2002
  35. pmc Digital clubbing in tuberculosis--relationship to HIV infection, extent of disease and hypoalbuminemia
    Henry Ddungu
    Department of Medicine, Makerere University and Mulago Hospital, Kampala, Uganda
    BMC Infect Dis 6:45. 2006
    ..The prevalence of clubbing in patients with pulmonary TB and its association with Human Immunodeficiency Virus (HIV), severity of disease, and nutritional status was assessed...