Firouz Daneshgari

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. doi request reprint History and development of an integrated model of care for female pelvic medicine and surgery
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Surgery, Urology Institute, Cleveland, OH Department of Urology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH Electronic address
    Urology 83:965-8. 2014
  2. pmc Diabetic bladder dysfunction: current translational knowledge
    Firouz Daneshgari
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA
    J Urol 182:S18-26. 2009
  3. pmc Animal models of diabetic uropathy
    Firouz Daneshgari
    Department of Urology and Female Pelvic Surgery, State University of New York, Upstate Medical University, Syracuse, New York, USA
    J Urol 182:S8-13. 2009
  4. pmc Stem cell homing factor, CCL7, expression in mouse models of stress urinary incontinence
    Adonis K Hijaz
    From the Department of Urology, Case Western Reserve University Urology Institute, University Hospitals Case Medical Center, Cleveland, OH, Center for Clinical Investigation, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan and Department of Urology, Lanzhou University Second Hospital, Lanzhou, China
    Female Pelvic Med Reconstr Surg 19:356-61. 2013
  5. pmc Uroplakin peptide-specific autoimmunity initiates interstitial cystitis/painful bladder syndrome in mice
    Kenan Izgi
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America Department of Clinical Chemistry, Cleveland State University, Cleveland, Ohio, United States of America
    PLoS ONE 8:e72067. 2013
  6. pmc Diabetes slows the recovery from urinary incontinence due to simulated childbirth in female rats
    Ja Hong Kim
    Glickman Urological Institute, Department of Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Regul Integr Comp Physiol 293:R950-5. 2007
  7. doi request reprint External urethral sphincter activity in diabetic rats
    Guiming Liu
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurourol Urodyn 27:429-34. 2008
  8. doi request reprint Lower urogenital tract anatomical and functional phenotype in lysyl oxidase like-1 knockout mice resembles female pelvic floor dysfunction in humans
    Una J Lee
    Glickman Urological and Kidney Institute, Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, OH, USA
    Am J Physiol Renal Physiol 295:F545-55. 2008
  9. ncbi request reprint Robotic abdominal sacrocolpopexy/sacrouteropexy repair of advanced female pelvic organ prolaspe (POP): utilizing POP-quantification-based staging and outcomes
    Firouz Daneshgari
    The Cleveland Clinic, Glickman Urological Institute, Cleveland, OH, USA
    BJU Int 100:875-9. 2007
  10. ncbi request reprint Time dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function
    Firouz Daneshgari
    Glickman Urological Institute, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Urol 176:380-6. 2006

Collaborators

Detail Information

Publications65

  1. doi request reprint History and development of an integrated model of care for female pelvic medicine and surgery
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Surgery, Urology Institute, Cleveland, OH Department of Urology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH Department of Obstetrics and Gynecology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH Electronic address
    Urology 83:965-8. 2014
    ....
  2. pmc Diabetic bladder dysfunction: current translational knowledge
    Firouz Daneshgari
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA
    J Urol 182:S18-26. 2009
    ..The most common, bothersome lower urinary tract complication of diabetes mellitus is diabetic cystopathy or diabetic bladder dysfunction. We reviewed the current translational knowledge of diabetic bladder dysfunction...
  3. pmc Animal models of diabetic uropathy
    Firouz Daneshgari
    Department of Urology and Female Pelvic Surgery, State University of New York, Upstate Medical University, Syracuse, New York, USA
    J Urol 182:S8-13. 2009
    ..Animal models have the potential to reveal mechanisms and aid in the development of treatment strategies...
  4. pmc Stem cell homing factor, CCL7, expression in mouse models of stress urinary incontinence
    Adonis K Hijaz
    From the Department of Urology, Case Western Reserve University Urology Institute, University Hospitals Case Medical Center, Cleveland, OH, Center for Clinical Investigation, Case Western Reserve University, University Hospitals Case Medical Center, Cleveland, OH Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan and Department of Urology, Lanzhou University Second Hospital, Lanzhou, China
    Female Pelvic Med Reconstr Surg 19:356-61. 2013
    ....
  5. pmc Uroplakin peptide-specific autoimmunity initiates interstitial cystitis/painful bladder syndrome in mice
    Kenan Izgi
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America Department of Clinical Chemistry, Cleveland State University, Cleveland, Ohio, United States of America
    PLoS ONE 8:e72067. 2013
    ..Our study demonstrates the creation of a more specific experimental autoimmune cystitis model that is the first inducible model for IC/PBS that manifests all of the major symptoms of this debilitating condition. ..
  6. pmc Diabetes slows the recovery from urinary incontinence due to simulated childbirth in female rats
    Ja Hong Kim
    Glickman Urological Institute, Department of Biomedical Engineering, The Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA
    Am J Physiol Regul Integr Comp Physiol 293:R950-5. 2007
    ..In conclusion, these findings suggest that DM causes increased severity and delayed functional recovery from the effects of simulated childbirth...
  7. doi request reprint External urethral sphincter activity in diabetic rats
    Guiming Liu
    Department of Biomedical Engineering, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    Neurourol Urodyn 27:429-34. 2008
    ..To examine the temporal effects of diabetes on the bladder and the external urethral sphincter (EUS) activity in rats...
  8. doi request reprint Lower urogenital tract anatomical and functional phenotype in lysyl oxidase like-1 knockout mice resembles female pelvic floor dysfunction in humans
    Una J Lee
    Glickman Urological and Kidney Institute, Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, OH, USA
    Am J Physiol Renal Physiol 295:F545-55. 2008
    ..The increase in elastin clusters in the urethra of LOXL1-KO mice with POP suggests that elastin disorganization may lead to functional abnormalities. We conclude that LOXL1 warrants further investigation in the pathphysiology of FPFD...
  9. ncbi request reprint Robotic abdominal sacrocolpopexy/sacrouteropexy repair of advanced female pelvic organ prolaspe (POP): utilizing POP-quantification-based staging and outcomes
    Firouz Daneshgari
    The Cleveland Clinic, Glickman Urological Institute, Cleveland, OH, USA
    BJU Int 100:875-9. 2007
    ..To assess the management of advanced pelvic organ prolapse (POP) with robotic-assisted abdominal sacrocolpopexy (RASC) and evaluate outcomes using the POP quantification scale (POP-Q)...
  10. ncbi request reprint Time dependent changes in diabetic cystopathy in rats include compensated and decompensated bladder function
    Firouz Daneshgari
    Glickman Urological Institute, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    J Urol 176:380-6. 2006
    ..While bladder filling and voiding problems have been reported, the precise functional changes in diabetic bladders remain unclear. We investigated time dependent changes in bladder function in streptozotocin induced diabetic rats...
  11. doi request reprint Voiding function in obese and type 2 diabetic female rats
    Gregory Gasbarro
    Research Service, Louis B Stokes Veterans Affairs Medical Center, Cleveland, Ohio, USA
    Am J Physiol Renal Physiol 298:F72-7. 2010
    ..Voiding dysfunction was evident in both obese groups but with no significant differences due to DMII, suggesting that voiding dysfunction in DMII may be attributable at least in part to chronic obesity...
  12. pmc Autoimmunity to uroplakin II causes cystitis in mice: a novel model of interstitial cystitis
    Cengiz Z Altuntas
    Department of Urology, University Hospitals, Case Western Reserve University, Cleveland, OH 44106, USA
    Eur Urol 61:193-200. 2012
    ..The pathophysiology of interstitial cystitis (IC) is unknown. Deficits in urothelial cell layers and autoimmune mechanisms may play a role...
  13. ncbi request reprint A mouse model of simulated birth trauma induced stress urinary incontinence
    Yi Hao Lin
    Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Neurourol Urodyn 27:353-8. 2008
    ....
  14. doi request reprint Robotic-assisted urethrolysis for urethral obstruction after retropubic bladder neck suspension-a case series report
    Bogdan Orasanu
    1 Department of Urology, University Hospitals Case Medical Center, Cleveland, Ohio
    J Endourol 28:214-8. 2014
    ..We report methods and results of performing robotic-assisted urethrolysis in patients with urethral obstruction after Burch colposuspension...
  15. ncbi request reprint Complications and troubleshooting of two-stage sacral neuromodulation therapy: a single-institution experience
    Adonis Hijaz
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA
    Urology 68:533-7. 2006
    ..The purpose of this study was to identify these events and their causes and management in our large single-institution experience...
  16. pmc A novel murine model of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) induced by immunization with a spermine binding protein (p25) peptide
    Cengiz Z Altuntas
    Department of Urology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA
    Am J Physiol Regul Integr Comp Physiol 304:R415-22. 2013
    ..This autoimmune prostatitis model provides a useful tool for exploring the pathophysiology and new treatments...
  17. pmc Efficacy of neuroselective and site-specific nociceptive stimuli of rat bladder
    Yasuhiro Yamada
    Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan
    Urology 79:483.e7-12. 2012
    ..To evaluate the organ specificity of sine wave electrical stimulation of the bladder through assessment of the expression of Fos-immunoreactive (IR) cells in rat spinal cord regions...
  18. doi request reprint Temporal diabetes and diuresis-induced alteration of nerves and vasculature of the urinary bladder in the rat
    Guiming Liu
    Department of Urology, Case Western Reserve University, Cleveland, OH 44106, USA
    BJU Int 107:1988-93. 2011
    ..To characterize the temporal changes of the nerves and vasculature of the bladder in diabetic rats...
  19. ncbi request reprint Temporal differences in bladder dysfunction caused by diabetes, diuresis, and treated diabetes in mice
    Firouz Daneshgari
    Glickman Urological Institute, and Department of Quantitative Health Sciences, Cleveland Clinic Foundation, 9500 Euclid Ave, ND50, Cleveland, OH 44195, USA
    Am J Physiol Regul Integr Comp Physiol 290:R1728-35. 2006
    ..Long-term insulin replacement effectively reversed most changes in bladder function. These results suggest that the transition from a compensated to a decompensated bladder dysfunction occurs 9-12 wk after induction of DM in mice by STZ...
  20. pmc Chronic pelvic allodynia is mediated by CCL2 through mast cells in an experimental autoimmune cystitis model
    Fuat Bicer
    Urology Institute, University Hospitals Case Medical Center and Department of Urology, Case Western Reserve University School of Medicine, Cleveland, Ohio Department of Clinical Chemistry, Cleveland State University, Cleveland, Ohio
    Am J Physiol Renal Physiol 308:F103-13. 2015
    ..These results show that UPK3A 65-84 immunization causes chronic visceral allodynia and suggest that it is mediated by CCL2-driven mast cell accumulation in the bladder. ..
  21. doi request reprint Successful induction of stress urinary incontinence in mice by vaginal distension does not depend on the estrous cycle
    Yexiang Huang
    Urology Institute, University Hospitals Case Medical Center, and Department of Urology, Case Western Reserve University School of Medicine, Cleveland, OH Department of Urology, The First Affiliated Hospital, China Medical University, Shenyang, China
    Urology 83:958.e1-6. 2014
    ..To determine if the performance of vaginal distension (VD) in different estrous cycle phases affects the successful induction of stress urinary incontinence in mice...
  22. pmc Pubo-urethral ligament transection causes stress urinary incontinence in the female rat: a novel animal model of stress urinary incontinence
    John C Kefer
    Glickman Urological Institute, Lerner Research Institute, The Cleveland Clinic, Cleveland, Ohio, USA
    J Urol 179:775-8. 2008
    ..We created a novel model of pubo-urethral ligament deficiency in the rat and validated our model through comparison with an established model of stress urinary incontinence...
  23. ncbi request reprint Role of sling integrity in the restoration of leak point pressure in the rat vaginal sling model
    Adonis Hijaz
    Glickman Urological Institute, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Urol 174:771-5. 2005
    ..We also examined the long-term effects of the sling on bladder function in a recently validated rat model of vaginal sling...
  24. ncbi request reprint Sacral neuromodulation in the older woman
    Sarah E McAchran
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Clin Obstet Gynecol 50:735-44. 2007
    ....
  25. ncbi request reprint Bladder and urethral function in pelvic organ prolapsed lysyl oxidase like-1 knockout mice
    Guiming Liu
    Glickman Urological Institute and Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA
    BJU Int 100:414-8. 2007
    ..To examine bladder and urethral function in pelvic organ prolapsed lysyl oxidase like-1 (LOXL1) knockout mice...
  26. doi request reprint Rate of de novo stress urinary incontinence after urethal diverticulum repair
    Una J Lee
    Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Urology 71:849-53. 2008
    ..Our objective was to determine the rate of de novo stress urinary incontinence (SUI) after urethral diverticulum repair...
  27. doi request reprint Pubo-urethral ligament injury causes long-term stress urinary incontinence in female rats: an animal model of the integral theory
    John C Kefer
    Glickman Urological Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA
    J Urol 181:397-400. 2009
    ..We examined the long-term effects of pubo-urethral ligament deficiency as a potential model of stress urinary incontinence compared to an established model of stress urinary incontinence...
  28. pmc Expression of monocyte chemotactic protein 3 following simulated birth trauma in a murine model of obesity
    Gino J Vricella
    Department of Urology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44113, USA
    Urology 76:1517.e12-7. 2010
    ..To determine the effect of obesity on simulated birth trauma in leptin-deficient obese mice as measured by relative monocyte chemotactic protein 3 (MCP-3) expression...
  29. ncbi request reprint Patient related risk factors for recurrent stress urinary incontinence surgery in women treated at a tertiary care center
    Firouz Daneshgari
    Glickman Urological Institute and Lerner Research Institute, and Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Urol 176:1493-9. 2006
    ..We examined patient related risk factors for recurrent stress urinary incontinence in women treated at a tertiary referral center...
  30. pmc Functional and morphological alterations of the urinary bladder in type 2 diabetic FVB(db/db) mice
    Liyang Wu
    Department of Surgery, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA Department of Urology, Beijing Chao Yang Hospital, Capital Medical University, Beijing, PRC
    J Diabetes Complications 30:778-85. 2016
    ..Diabetic bladder dysfunction (DBD) has been extensively studied in animal models of type 1 diabetes. We aimed to examine the functional and morphological alterations of the urinary bladder in a type 2 diabetes model, FVB(db/db) mice...
  31. pmc Mesenchymal stem cell therapy in a rat model of birth-trauma injury: functional improvements and biodistribution
    Zhina Sadeghi
    Urology Institute, University Hospitals of Case Medical Center, Department of Urology, Case Western Reserve University, 11100 Euclid Avenue, Cleveland, OH, 44106, USA
    Int Urogynecol J 27:291-300. 2016
    ..We evaluated the potential role of human mesenchymal stem cells (hMSCs) in improvement of urinary continence following birth-trauma injury...
  32. pmc Bladder function in mice with inducible smooth muscle-specific deletion of the manganese superoxide dismutase gene
    Guiming Liu
    Department of Urology, Case Western Reserve University School of Medicine, Cleveland, Ohio
    Am J Physiol Cell Physiol 309:C169-78. 2015
    ..This novel model can be used for exploring the mechanistic role of oxidative stress in organs rich in SM in different pathological conditions. ..
  33. pmc Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder
    Cengiz Z Altuntas
    Urology Institute, Univ Hospitals Case Medical Center Dept of Urology, Case Western Reserve Univ School of Medicine 11100 Euclid Ave, Lakeside Bldg, Ste 4554, Cleveland, OH 44106, USA
    Am J Physiol Renal Physiol 303:F1363-9. 2012
    ..Our results suggest that bladder remodeling corresponding to EAE severity may be due to enhanced expression of CTGF and increased growth of connective tissue...
  34. pmc Calcineurin and Akt expression in hypertrophied bladder in STZ-induced diabetic rat
    Guiming Liu
    Glickman Urological and Kidney Institute and Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    Exp Mol Pathol 92:210-6. 2012
    ..Our results suggest that the Cn, but not the Akt signaling pathway may be involved in the development of bladder hypertrophy...
  35. ncbi request reprint The impact of cesarean delivery on pelvic floor dysfunction in lysyl oxidase like-1 knockout mice
    Arlan Marcus Gustilo-Ashby
    From the Center for Urogynecology and Reconstructive Surgery, Obstetrics, Gynecology and Women s Health Institute, Cleveland Clinic, Cleveland, OH Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH Research Service, Department of Veterans Affairs Medical Center, Louis Stokes Cleveland, Cleveland, OH and Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH
    Female Pelvic Med Reconstr Surg 16:21-30. 2010
    ..The objective of this study was to test the hypothesis that tissue changes associated with vaginal delivery lead to pelvic floor dysfunction as a result of abnormal elastic fiber homeostasis...
  36. pmc The minimum important differences for the urinary scales of the Pelvic Floor Distress Inventory and Pelvic Floor Impact Questionnaire
    Matthew D Barber
    Obstetrics, Gynecology, and Women s Health Institute, Cleveland Clinic, Cleveland, OH, USA
    Am J Obstet Gynecol 200:580.e1-7. 2009
    ....
  37. pmc Collagen remodeling and suburethral inflammation might account for preserved anti-incontinence effects of cut polypropylene sling in rat model
    Chi Chiung Grace Chen
    Department of Obstetrics and Gynecology, Cleveland Clinic, Cleveland, Ohio, USA
    Urology 73:415-20. 2009
    ..To determine whether the inflammatory responses or collagen remodeling in suburethral tissue could have contributed to the preserved anti-incontinence effects of a cut polypropylene sling...
  38. ncbi request reprint Advancing the understanding of pathophysiological rationale for the treatment of stress urinary incontinence in women: the 'trampoline theory'
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    BJU Int 98:8-14; discussion 15-6. 2006
  39. ncbi request reprint Advances in geriatric female pelvic surgery
    Humphrey Atiemo
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
    BJU Int 98:90-4; discussion 95-6. 2006
  40. ncbi request reprint Open and unresolved clinical questions in female pelvic medicine and reconstructive surgery
    Michael Albo
    Department of Urology, University of California San Diego, San Diego, CA, USA
    BJU Int 98:110-6. 2006
  41. pmc Animal models of female stress urinary incontinence
    Adonis Hijaz
    Department of Urology, Case Western Reserve University, Cleveland, Ohio, USA
    J Urol 179:2103-10. 2008
    ....
  42. pmc Temporal morphological and functional impact of complete urinary diversion on the bladder: a model of bladder disuse in rats
    Guiming Liu
    Department of Urology, Case Western Reserve University, Cleveland, Ohio 44106, USA
    J Urol 184:2179-85. 2010
    ..Urinary diversion has been used as a surgical option for some bladder diseases. We developed a urinary diversion model in the rat and examined the effects of urinary diversion on the bladder...
  43. ncbi request reprint Applications of neuromodulation of the lower urinary tract in female urology
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Int Braz J Urol 32:262-72. 2006
    ..In addition, we will discuss some of the newer developments in SNS such as Bion device and the future direction in integration of SNS in female urology...
  44. ncbi request reprint Reliability and agreement of urodynamics interpretations in a female pelvic medicine center
    James L Whiteside
    Department of Quantitative Health Sciences, Center for Female Pelvic Medicine, Cleveland Clinic Foundation, Ohio, USA
    Obstet Gynecol 108:315-23. 2006
    ..To estimate the reliability and interobserver consistency of urodynamic interpretations of female bladder and urethral function...
  45. doi request reprint Complications of mid urethral slings: important outcomes for future clinical trials
    Firouz Daneshgari
    Department of Urology and Female Pelvic Surgery, Upstate Medical University, Syracuse, New York 13210, USA
    J Urol 180:1890-7. 2008
    ..Mid urethral slings are becoming the first line surgical treatment for stress urinary incontinence in women. We reviewed the complications of mid urethral sling placement and their potential pathophysiology...
  46. ncbi request reprint Long-term efficacy of a vaginal sling procedure in a rat model of stress urinary incontinence
    Adonis Hijaz
    Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Urol 173:1817-9. 2005
    ..We examined the long-term efficacy of a newly created vaginal sling procedure for the restoration of leak point pressure (LPP) in a rat model of stress urinary incontinence (SUI)...
  47. pmc Bladder dysfunction in mice with experimental autoimmune encephalomyelitis
    Cengiz Z Altuntas
    Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Neuroimmunol 203:58-63. 2008
    ..Our study is the first to show and characterize micturition abnormalities in EAE mice thereby providing a most useful model system for understanding and treating neurogenic bladder...
  48. doi request reprint Differences in urinary incontinence between Hispanic and non-Hispanic white women: a population-based study
    Firouz Daneshgari
    Glickman Urological Institute, The Cleveland Clinic, Cleveland, OH OH 44195, USA
    BJU Int 101:575-9. 2008
    ..To compare the prevalence of urinary incontinence (UI) between Hispanic and non-Hispanic White women in a population-based study...
  49. ncbi request reprint Temporal diabetes- and diuresis-induced remodeling of the urinary bladder in the rat
    Guiming Liu
    Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Physiol Regul Integr Comp Physiol 291:R837-43. 2006
    ..Diabetes-induced diuresis caused adaptive physical changes in rat bladder by 4 days after induction; remodeling was observed by 2-3 wk after induction and remained stable from 3 to 9 wk...
  50. ncbi request reprint Effects of cold storage on the function and morphology of isolated urinary bladder in rat
    Guiming Liu
    Glickman Urological Institute and Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Neurourol Urodyn 25:381-7. 2006
    ..We investigated the effects of 24- and 48-hr storage at 4 degrees C in Krebs solution on the function and morphology of isolated, rat urinary bladders...
  51. pmc Efficacy of a novel device for assessment of autonomic sensory function in the rat bladder
    Robert Abouassaly
    Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Urol 179:1167-72. 2008
    ..We developed and tested the efficacy of an implantable bladder device which, when combined with the Neurometer, can be used to assess fiber specific afferent bladder sensation in the rat...
  52. pmc Outcomes following vaginal prolapse repair and mid urethral sling (OPUS) trial--design and methods
    John Wei
    Department of Urology, University of Michigan, Ann Arbor, Michigan, USA
    Clin Trials 6:162-71. 2009
    ....
  53. pmc Obesity-initiated metabolic syndrome promotes urinary voiding dysfunction in a mouse model
    Qiqi He
    Department of Urology, Case Western Reserve University and University Hospitals Case Medical Center, Cleveland, Ohio
    Prostate 76:964-76. 2016
    ..Nevertheless, there is lack of suitable animal model(s) which could illustrate an association linking obesity to LUTS. We examined the lower urinary tract function in an obesity-initiated MetS mouse model...
  54. pmc Assessment of bladder sensation in mice with a novel device
    Fuat Bicer
    Urology Institute, University Hospitals Case Medical Center, Cleveland, OH Department of Urology, Case Western Reserve University School of Medicine, Cleveland, OH
    Urology 84:490.e1-6. 2014
    ..To develop and test the efficacy of an implantable bladder electrode device that can be used with the Neurometer electrodiagnostic stimulator to assess fiber-specific afferent bladder sensation in the mouse...
  55. ncbi request reprint Efficacy of a vaginal sling procedure in a rat model of stress urinary incontinence
    Adonis Hijaz
    Glickman Urological Institute and Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Urol 172:2065-8. 2004
    ..We validated the efficacy of the vaginal sling procedure for the restoration of leak point pressure (LPP) in the rat model of stress urinary incontinence (SUI)...
  56. ncbi request reprint Alterations in neurogenically mediated contractile responses of urinary bladder in rats with diabetes
    Guiming Liu
    Glickman Urological Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am J Physiol Renal Physiol 288:F1220-6. 2005
    ..In conclusion, neurogenically mediated bladder contraction is altered in the diabetic rat. Diabetic-related changes do not parallel diuretic-induced changes, indicating that the pathogenesis of DBD needs further exploration...
  57. doi request reprint Advanced maternal age as a risk factor for stress urinary incontinence: a review of the literature
    Adonis Hijaz
    Department of Urology, Case Western Reserve University, University Hospitals of Case Medical Center, Cleveland, OH 44106, USA
    Int Urogynecol J 23:395-401. 2012
    ..However, long-term studies did not confirm this observation. Whether this finding is suggestive of a true biologic signal that is lost with competing risk factors over time warrants further research...
  58. ncbi request reprint Future directions in pelvic neuromodulation
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A100, Cleveland, OH 44195, USA
    Urol Clin North Am 32:113-5, viii. 2005
    ..The aim of this research is to determine ifa less invasive, more selective stimulation or an event-driven (detrusor overactivity ora desire for micturition) stimulus would allow for a more improved and durable response...
  59. ncbi request reprint Robotic and laparoscopic female pelvic floor reconstruction
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, The Cleveland Clinic, Cleveland, OH 44195, USA
    BJU Int 98:62-8; discussion 69. 2006
  60. pmc Pudendal nerve injury reduces urethral outlet resistance in diabetic rats
    Hui Q Pan
    Cleveland Clinic, Cleveland, OH 44195, USA
    Am J Physiol Renal Physiol 299:F1443-50. 2010
    ..AGEs were significantly elevated in diabetic rats. PNC relieves a functional outlet obstruction in diabetic rats. AGEs are elevated in diabetic rats and could play a role in urinary dysfunction and recovery from PNC...
  61. ncbi request reprint Diabetic uropathy
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Semin Nephrol 26:182-5. 2006
    ..In order to decrease the number and severity of diabetic urologic complications, early recognition and a more comprehensive understanding of how diabetes impacts the genitourinary tract is imperative...
  62. pmc Diabetic bladder dysfunction
    Guiming Liu
    Urology Institute, University Hospitals Case Medical Center, and Department of Urology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA Email
    Chin Med J (Engl) 127:1357-64. 2014
    ..To review studies on diabetic bladder dysfunction (DBD), a common and bothersome complication of diabetes mellitus...
  63. ncbi request reprint Management of ureteral injuries associated with vaginal surgery for pelvic organ prolapse
    Ja Hong Kim
    Glickman Urological Institute, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Int Urogynecol J Pelvic Floor Dysfunct 17:531-5. 2006
    ..The present study illustrates the application of our treatment algorithm based on the time of presentation and the patient condition...
  64. ncbi request reprint Surgical innovations in pelvic organ prolapse and incontinence
    Humphrey Atiemo
    Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, The Cleveland Clinic, 9500 Euclid Avenue A100, Cleveland, OH 44195, USA
    Clin Geriatr Med 22:605-21. 2006
    ..This article examines the current medical and surgical innovations for POP and UI that have the potential to improve the patient's quality of life...
  65. ncbi request reprint Current indications for neuromodulation
    Firouz Daneshgari
    Center for Female Pelvic Medicine and Reconstructive Surgery, Glickman Urological Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Urol Clin North Am 32:37-40, vi. 2005
    ..Currently, neuromodulation may consist of the use of nerve stimulation and injectable therapies. This article concentrates on nerve stimulation...