Jill S Barnholtz-Sloan

Summary

Affiliation: Case Western Reserve University
Country: USA

Publications

  1. pmc A multi-center population-based case-control study of ovarian cancer in African-American women: the African American Cancer Epidemiology Study (AACES)
    Joellen M Schildkraut
    Duke Cancer Institute, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
    BMC Cancer 14:688. 2014
  2. pmc Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine Cleveland, OH, USA
    Front Genet 2:37. 2011
  3. pmc Splitting random forest (SRF) for determining compact sets of genes that distinguish between cancer subtypes
    Xiaowei Guan
    Case Comprehensive Cancer Center, 11100 Euclid Avenue, Cleveland, OH, USA
    J Clin Bioinforma 2:13. 2012
  4. pmc A nomogram for individualized estimation of survival among patients with brain metastasis
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Neuro Oncol 14:910-8. 2012
  5. pmc Assessing the impact of global versus local ancestry in association studies
    Sun Jung Kang
    Department of Epidemiology and Biostatistics, Division of Genetic and Molecular Epidemiology, Case Western Reserve University School of Medicine, Wolstein Research Building, 2103 Cornell Road, Cleveland, Ohio 44106 USA
    BMC Proc 3:S107. 2009
  6. ncbi request reprint Meningiomas: causes and risk factors
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 5065, USA
    Neurosurg Focus 23:E2. 2007
  7. doi request reprint Incidence trends of invasive cervical cancer in the United States by combined race and ethnicity
    Jill Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Cancer Causes Control 20:1129-38. 2009
  8. ncbi request reprint Racial/ethnic differences in survival among elderly patients with a primary glioblastoma
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106 5065, USA
    J Neurooncol 85:171-80. 2007
  9. pmc FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Carcinogenesis 31:1417-23. 2010
  10. pmc Decision tree-based modeling of androgen pathway genes and prostate cancer risk
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Cancer Epidemiol Biomarkers Prev 20:1146-55. 2011

Research Grants

  1. Analysis of Ethnic Admixture in Lung Cancer
    Jill Barnholtz Sloan; Fiscal Year: 2006

Detail Information

Publications65

  1. pmc A multi-center population-based case-control study of ovarian cancer in African-American women: the African American Cancer Epidemiology Study (AACES)
    Joellen M Schildkraut
    Duke Cancer Institute, Department of Community and Family Medicine, Duke University Medical Center, Durham, NC, USA
    BMC Cancer 14:688. 2014
    ..To study the epidemiology of OVCA in this population, we started a collaborative effort in 10 sites in the US. Here we describe the study and highlight the challenges of conducting a study of a lethal disease in a minority population...
  2. pmc Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine Cleveland, OH, USA
    Front Genet 2:37. 2011
    ..We show that genetic associations by race are modified by interaction between individual SNPs and PS...
  3. pmc Splitting random forest (SRF) for determining compact sets of genes that distinguish between cancer subtypes
    Xiaowei Guan
    Case Comprehensive Cancer Center, 11100 Euclid Avenue, Cleveland, OH, USA
    J Clin Bioinforma 2:13. 2012
    ..The goal is to improve the prediction accuracy while considering sparsity...
  4. pmc A nomogram for individualized estimation of survival among patients with brain metastasis
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Neuro Oncol 14:910-8. 2012
    ..An estimated 24%-45% of patients with cancer develop brain metastases. Individualized estimation of survival for patients with brain metastasis could be useful for counseling patients on clinical outcomes and prognosis...
  5. pmc Assessing the impact of global versus local ancestry in association studies
    Sun Jung Kang
    Department of Epidemiology and Biostatistics, Division of Genetic and Molecular Epidemiology, Case Western Reserve University School of Medicine, Wolstein Research Building, 2103 Cornell Road, Cleveland, Ohio 44106 USA
    BMC Proc 3:S107. 2009
    ....
  6. ncbi request reprint Meningiomas: causes and risk factors
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106 5065, USA
    Neurosurg Focus 23:E2. 2007
    ..Gaining a better understanding of the origin of this disease is essential so that treatments and outcomes can be improved and prevention strategies can be developed...
  7. doi request reprint Incidence trends of invasive cervical cancer in the United States by combined race and ethnicity
    Jill Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Cancer Causes Control 20:1129-38. 2009
    ..To better understand national patterns of invasive cervical cancer (ICC) incidence by race and ethnicity in order to develop appropriate ICC prevention policies...
  8. ncbi request reprint Racial/ethnic differences in survival among elderly patients with a primary glioblastoma
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106 5065, USA
    J Neurooncol 85:171-80. 2007
    ....
  9. pmc FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Carcinogenesis 31:1417-23. 2010
    ..Several new haplotypes were associated with breast cancer in AA and younger women, particularly the FGFR2 GTGT haplotype. These results highlight the need to conduct GWAS among younger women and in a variety of racial-ethnic populations...
  10. pmc Decision tree-based modeling of androgen pathway genes and prostate cancer risk
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106 5065, USA
    Cancer Epidemiol Biomarkers Prev 20:1146-55. 2011
    ..e., decision trees), and to evaluate whether these interactive effects add information about prostate cancer risk prediction beyond that of "traditional" risk factors...
  11. doi request reprint Ancestry estimation and correction for population stratification in molecular epidemiologic association studies
    Jill S Barnholtz-Sloan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH 44106 5065, USA
    Cancer Epidemiol Biomarkers Prev 17:471-7. 2008
  12. pmc Completeness of required site-specific factors for brain and CNS tumors in the Surveillance, Epidemiology and End Results (SEER) 18 database (2004-2012, varying)
    Quinn T Ostrom
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Wearn 152, Cleveland, OH, 44106, USA
    J Neurooncol 130:31-42. 2016
    ..It is critical that cancer registries continue to collect established and emerging prognostic and predictive factors...
  13. doi request reprint Risk of subsequent primary malignancies after dermatofibrosarcoma protuberans diagnosis: a national study
    David E Kurlander
    Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Am Acad Dermatol 68:790-6. 2013
    ..Patients frequently live many years after diagnosis of dermatofibrosarcoma protuberans (DFSP)...
  14. pmc ENVE: a novel computational framework characterizes copy-number mutational landscapes in colorectal cancers from African American patients
    Vinay Varadan
    Division of General Medical Sciences Oncology, Case Western Reserve University, Cleveland, OH 44106 USA Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106 USA Case Western Reserve University, 2103 Cornell Road, Wolstein Research Building, Cleveland, OH 44106 USA
    Genome Med 7:69. 2015
    ..ENVE is downloadable at https://github.com/ENVE-Tools/ENVE...
  15. pmc A variable age of onset segregation model for linkage analysis, with correction for ascertainment, applied to glioma
    Xiangqing Sun
    Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Cancer Epidemiol Biomarkers Prev 21:2242-51. 2012
    ..We propose a 2-step model-based approach, with correction for ascertainment, to linkage analysis of a binary trait with variable age of onset and apply it to a set of multiplex pedigrees segregating for adult glioma...
  16. pmc Aberrant vimentin methylation is characteristic of upper gastrointestinal pathologies
    Helen Moinova
    Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
    Cancer Epidemiol Biomarkers Prev 21:594-600. 2012
    ..We now examine vimentin methylation in neoplasia of the upper gastrointestinal tract...
  17. pmc Years of potential life lost for brain and CNS tumors relative to other cancers in adults in the United States, 2010
    Chaturia Rouse
    Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, Ohio C R Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio H G, Q T O, J S B S Central Brain Tumor Registry of the United States, Hinsdale, Illinois H G, Q T O, C K, J S B S
    Neuro Oncol 18:70-7. 2016
    ..In this study, we examine the impact of death due to brain and other central nervous system (CNS) tumors compared to other common cancers in adults by investigating the YPLL of adults in the United States...
  18. doi request reprint Incidence of vestibular schwannomas in the United States
    Varun R Kshettry
    Department of Neurosurgery, Neurological Institute, Cleveland Clinic, 9500 Euclid Ave, S40, Cleveland, OH, 44195, USA
    J Neurooncol 124:223-8. 2015
    ..09 per 100,000 population. Incidence increases with age up to the 65-74 year old age group. Incidence is higher in Asian Pacific Islanders and lower in African Americans and Hispanics. ..
  19. pmc Years of life lived with disease and years of potential life lost in children who die of cancer in the United States, 2009
    Peter M de Blank
    Department of Pediatric Hematology Oncology, Rainbow Babies and Children s Hospital, 11100 Euclid Ave, Cleveland, Ohio Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, Ohio
    Cancer Med 4:608-19. 2015
    ..YPLL and YLLD complement traditional indicators of mortality and help place CNS tumors in the context of other childhood malignancies...
  20. pmc The descriptive epidemiology of atypical teratoid/rhabdoid tumors in the United States, 2001-2010
    Quinn T Ostrom
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio Q T O, Y C, H G, Y W, J S B S Central Brain Tumor Registry of the United States, Hinsdale, Illinois Q T O, Y C, H G, Y W, C K, J S B S Division of Pediatric Hematology Oncology, Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio P M d B The Ohio State University, Columbus, Ohio A O Case Western Reserve University, Cleveland, Ohio P F Department of Pathology, University Hospitals Case Medical Center, Cleveland, Ohio M L C Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Emory University Hospital, Atlanta, Georgia D J B
    Neuro Oncol 16:1392-9. 2014
    ..Its data were used to describe the incidence, associated trends, and relative survival after diagnosis of atypical teratoid/rhabdoid tumor...
  21. pmc Variation in age at cancer diagnosis in familial versus nonfamilial Barrett's esophagus
    Amitabh Chak
    Division of Gastroenterology, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Cancer Epidemiol Biomarkers Prev 21:376-83. 2012
    ..In this study, we determine whether cancers develop at an earlier age in multiplex Familial Barrett's Esophagus (FBE) kindreds, defined by 3 or more members affected by Barrett's esophagus (BE) or esophageal adenocarcinoma (EAC)...
  22. pmc Completeness and concordancy of WHO grade assignment for brain and central nervous system tumors in the United States, 2004-2011
    Ryan L Lym
    Case Western Reserve University School of Medicine, 11100 Euclid Avenue, Cleveland, OH, USA
    J Neurooncol 123:43-51. 2015
    ..Data collection on grade has improved in completeness and concordancy over time. Efforts to further improve collection of this variable are essential for clinical care and the epidemiological surveillance of CNS tumors...
  23. doi request reprint Descriptive Epidemiology of Spinal Meningiomas in the United States
    Varun R Kshettry
    Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, OH Cleveland Clinic Lerner College of Medicine, Cleveland, OH Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH and Central Brain Tumor Registry of the United States, Hinsdale, IL
    Spine (Phila Pa 1976) 40:E886-9. 2015
    ..Cross-sectional study of US cancer registry data...
  24. doi request reprint Incidence and Survival of Primary Dermatofibrosarcoma Protuberans in the United States
    Kathryn L Kreicher
    Departments of Dermatology, and Plastic Surgery, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio Department of Epidemiology and Biostatistics, Case Comprehensive Cancer Center, Cleveland, Ohio
    Dermatol Surg 42:S24-31. 2016
    ..Dermatofibrosarcoma protuberans (DFSP) is a rare cutaneous sarcoma for which data on risk factors, incidence, and survival are limited...
  25. pmc Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs
    Stephen P Fink
    Department of Medicine and Case Comprehensive Cancer Center, Case Western Reserve University and Case Medical Center, Cleveland, OH 44106, USA
    Carcinogenesis 36:291-8. 2015
    ..These findings suggest that sulindac may be the most effective agent for colon cancer prevention in humans with low 15-PGDH, but its use may also be associated with inflammatory lesions in the colon...
  26. pmc Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011
    Quinn T Ostrom
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH USA Central Brain Tumor Registry of the United States, Hinsdale, IL USA
    Neuro Oncol 16:x1-x36. 2015
    ..This report aims to serve as a useful resource for researchers, clinicians, patients, and families...
  27. doi request reprint Epidemiology of gliomas
    Quinn T Ostrom
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 11100 Euclid Ave Wearn 152, Cleveland, OH, 44106 5065, USA
    Cancer Treat Res 163:1-14. 2015
    ..The following chapter provides an overview of the current state of research in the epidemiology of intracranial glioma. ..
  28. pmc Molecular subtypes of glioblastoma are relevant to lower grade glioma
    Xiaowei Guan
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio, United States of America
    PLoS ONE 9:e91216. 2014
    ..The intent was to evaluate the relevance of known glioblastoma (GBM) expression and methylation based subtypes to grade II and III gliomas (ie. lower grade gliomas)...
  29. doi request reprint Risk and survival of cutaneous melanoma diagnosed subsequent to a previous cancer
    Geoffrey B Yang
    Comprehensive Cancer Center, Case Western Reserve School of Medicine, Cleveland, OH 44106, USA
    Arch Dermatol 147:1395-402. 2011
    ..To understand the risk of cutaneous melanoma (CM) following a previous cancer...
  30. pmc Identifying stage-specific protein subnetworks for colorectal cancer
    Sinan Erten
    Department of Electrical Engineering and Computer Science, Case Western Reserve University, Cleveland, OH, USA
    BMC Proc 6:S1. 2012
    ..These algorithms use protein-protein interaction (PPI) networks as an integrative framework and identify subnetworks that are coordinately dysregulated in the phenotype of interest...
  31. pmc Incidence patterns for primary malignant spinal cord gliomas: a Surveillance, Epidemiology, and End Results study
    Steven Hsu
    Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA
    J Neurosurg Spine 14:742-7. 2011
    ....
  32. pmc Reproductive and hormonal risk factors for ductal carcinoma in situ of the breast
    Lynette S Phillips
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA
    Cancer Epidemiol Biomarkers Prev 18:1507-14. 2009
    ..51; 95% CI, 0.25-1.04). Our results support the theory that comedo-type DCIS may share hormonal and reproductive risk factors with IBC, whereas the etiology of non-comedo DCIS deserves further investigation...
  33. ncbi request reprint An independently validated nomogram for individualized estimation of survival among patients with newly diagnosed glioblastoma: NRG Oncology RTOG 0525 and 0825
    Haley Gittleman
    Case Western Reserve University, Cleveland, Ohio H G, D L, S S, L, M M, A E S, D T, J S B S Cleveland Clinic Foundation, Cleveland, Ohio M W K, M A V Ohio State University, Columbus, Ohio A C National Institutes of Health Clinical Center, Bethesda, Maryland M R G Department of Neurology and Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, USA A B L, T J C W MD Anderson Cancer Center, Houston, Texas E P S, M P P Barrow Neurological Institute, Arizona Oncology Services Foundation, Phoenix, Arizona E Y Tel Aviv Medical Center, Tel Aviv University, Tel Aviv, Israel D T B NRG Oncology Statistics and Data Management Center, Philadelphia, Pennsylvania P Z Miami Cancer Institute, Miami, Florida M P M
    Neuro Oncol . 2016
    ....
  34. doi request reprint A Trial Online Educational Melanoma Program Aimed at the Hispanic Population Improves Knowledge and Behaviors
    Carly J Roman
    Case Western Reserve University School of Medicine, Cleveland, Ohio Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio Department of Dermatology, University Hospitals Case Medical Center, Cleveland, Ohio
    Dermatol Surg 42:672-6. 2016
    ..Hispanic individuals who suffer from melanoma are diagnosed later and have a worse prognosis. Because the Hispanic population is one of the fastest growing in the United States, it is important to spread awareness of melanoma...
  35. doi request reprint Complete prevalence of malignant primary brain tumors registry data in the United States compared with other common cancers, 2010
    Adah S Zhang
    Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio A S Z Department of Statistical Sciences, Sandia National Laboratories, Albuquerque, New Mexico A S Z Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio Q T O, L R, D M P, J S B Central Brain Tumor Registry of the United States CBTRUS, Hinsdale, Illinois Q T O, C K, J S B Brain Tumor and Neuro Oncology Center, University Hospitals Case Medical Center, Cleveland, Ohio L R Rose Ella Burkhardt Brain Tumor and Neuro Oncology Center, Neurological Institute, Cleveland Clinic, Cleveland, Ohio D M P
    Neuro Oncol . 2016
    ....
  36. pmc Descriptive epidemiology of World Health Organization grades II and III intracranial meningiomas in the United States
    Varun R Kshettry
    Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio V R K, G H B Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio Q T O, C K, J S B S Central Brain Tumor Registry of the United States, Hinsdale, Illinois Q T O, C K, J S B S Department of Neurosurgery, Brigham and Women s Hospital, Harvard School of Medicine, Boston, Massachusetts O A M Brain Tumor and Neuro Oncology Center, Cleveland Clinic, Cleveland, Ohio G H B
    Neuro Oncol 17:1166-73. 2015
    ..Our purpose was to provide a modern, population-based study of the descriptive epidemiology of WHO II and III meningiomas in the United States...
  37. pmc Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival
    Stephen P Fink
    Department of Medicine, Case Western Reserve University and Case Medical Center, Cleveland, OH, USA
    Oncotarget 6:30500-15. 2015
    ..We present CEMIP as a candidate prognostic marker for colon cancer and a potential therapeutic target. ..
  38. pmc Colonic 15-PGDH levels are stable across distance and time and are not perturbed by aspirin intervention
    Stephen P Fink
    Department of Medicine, Case Western Reserve University and Case Medical Center, 10900 Euclid Ave, Wolstein Research Building, Rm 3 128, Cleveland, OH 44106 7285, USA
    Dig Dis Sci 58:2615-22. 2013
    ....
  39. pmc Gene interaction enrichment and network analysis to identify dysregulated pathways and their interactions in complex diseases
    Yu Liu
    Center for Proteomics and Bioinformatics, Case Western Reserve University, Cleveland, OH 44106, USA
    BMC Syst Biol 6:65. 2012
    ..However, the dynamics of the interactions with respect to disease have been less well studied (i.e., properties of components ii and iii)...
  40. pmc RNA Sequencing Identifies Transcriptionally Viable Gene Fusions in Esophageal Adenocarcinomas
    Andrew E Blum
    Division of General Medical Sciences Oncology, Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio
    Cancer Res 76:5628-5633. 2016
    ..Cancer Res; 76(19); 5628-33. ©2016 AACR...
  41. pmc A Cross-sectional Study of KLKB1 and PRCP Polymorphisms in Patient Samples with Cardiovascular Disease
    Haley R Gittleman
    Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH, USA
    Front Med (Lausanne) 3:17. 2016
    ....
  42. doi request reprint Epidemiology of Anorectal Melanoma in the United States: 1992 to 2011
    Adrienne Callahan
    Department of Dermatology, University Hospitals Case Medical Center, Cleveland, Ohio Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, Maryland and Case Comprehensive Cancer Center, Cleveland, Ohio
    Dermatol Surg 42:94-9. 2016
    ..Anorectal melanoma is a rare type of malignant melanoma and thus the epidemiology of patients with this tumor has been poorly defined...
  43. pmc Identification of variants in primary and recurrent glioblastoma using a cancer-specific gene panel and whole exome sequencing
    Selene M Virk
    Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA
    PLoS ONE 10:e0124178. 2015
    ....
  44. pmc Pharmacogenomic approach to identify drug sensitivity in small-cell lung cancer
    Gary Wildey
    Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, United States of America
    PLoS ONE 9:e106784. 2014
    ..Taken together, this study outlines an approach to predict drug sensitivity in SCLC to novel targeted therapeutics. ..
  45. pmc Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010
    Haley R Gittleman
    Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio Central Brain Tumor Registry of the United States CBTRUS, Hinsdale, Illinois
    Cancer 121:102-12. 2015
    ..In this analysis, the authors examined trends in the incidence of the most common cancers and CNST between 2000 and 2010...
  46. pmc Family history of cancer in benign brain tumor subtypes versus gliomas
    Quinn T Ostrom
    Department of Anthropology, Case Western Reserve University Cleveland, OH, USA
    Front Oncol 2:19. 2012
    ..Conclusion: The results suggest that benign brain tumor may have an association with family history of cancer. More studies are warranted to disentangle the potential genetic and/or environmental causes for these diseases...
  47. doi request reprint Current state of our knowledge on brain tumor epidemiology
    Quinn T Ostrom
    Department of Anthropology, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
    Curr Neurol Neurosci Rep 11:329-35. 2011
    ..Recently studies of genetic risk factors for brain tumors have expanded to genome-wide association studies. In addition, genome-wide studies of somatic genetic changes in tumors show correlation with clinical outcomes...
  48. ncbi request reprint Racial differences in survival after diagnosis with primary malignant brain tumor
    Jill S Barnholtz-Sloan
    Department of Internal Medicine, Division of Hematology Oncology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Cancer 98:603-9. 2003
    ..The objective of this study was to examine racial differences in survival after diagnosis with primary malignant brain tumor in a population-based sample of patients while adjusting for prognostic variables that differ by race...
  49. ncbi request reprint Relative survival rates and patterns of diagnosis analyzed by time period for individuals with primary malignant brain tumor, 1973-1997
    Jill S Barnholtz-Sloan
    Department of Internal Medicine, Division of Hematology Oncology, Wayne State University School of Medicine, and the Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    J Neurosurg 99:458-66. 2003
    ....
  50. ncbi request reprint Survival analysis of distant prostate cancer by decade (1973-1997) in the Detroit Metropolitan Surveillance, Epidemiology and End Results (SEER) Program registry: has outcome improved? (United States)
    Jill S Barnholtz-Sloan
    Division of Hematology Oncology, Department of Internal Medicine, Wayne State University School of Medicine and The Barbara Ann Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Cancer Causes Control 14:681-5. 2003
    ..The purpose of this study is to examine differences in survival after diagnosis with distant stage prostate cancer by decade of diagnosis...
  51. doi request reprint Patterns of care and outcomes among elderly individuals with primary malignant astrocytoma
    Jill S Barnholtz-Sloan
    H Lee Moffitt Cancer Center and Research Institute, College of Public Health, University of South Florida, Tampa, Florida, USA
    J Neurosurg 108:642-8. 2008
    ..The odds of undergoing various combinations of treatments and the associations with outcome were calculated by tumor type and age and adjusted by various predictors...
  52. ncbi request reprint Pediatric brain tumors in non-Hispanics, Hispanics, African Americans and Asians: differences in survival after diagnosis
    Jill S Barnholtz-Sloan
    H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, 33612, MRC CANCONT Tampa, FL 33612, USA
    Cancer Causes Control 16:587-92. 2005
    ..The objective of this study was to assess racial differences in survival of children with brain tumors, focusing on Hispanics, African Americans and Asians compared to Non-Hispanics...
  53. ncbi request reprint A population-based study of racial and ethnic differences in survival among women with invasive cervical cancer: analysis of Surveillance, Epidemiology, and End Results data
    Divya A Patel
    Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Gynecol Oncol 97:550-8. 2005
    ....
  54. ncbi request reprint Incidence trends in primary malignant penile cancer
    Jill S Barnholtz-Sloan
    Division of Cancer Prevention and Control, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA
    Urol Oncol 25:361-7. 2007
    ..To examine trends in the incidence of primary, malignant penile cancer in the United States...
  55. ncbi request reprint Informativeness of the CODIS STR loci for admixture analysis
    Jill S Barnholtz-Sloan
    H Lee Moffitt Cancer Center and Research Institute Tampa, FL 33612, USA
    J Forensic Sci 50:1322-6. 2005
    ..We conclude that the FBI CODIS Core STR set is valid for admixture analysis, but not the most precise. We recommend using a combination of the most informative markers from the HGDP-CEPH and Shriver loci sets...
  56. pmc Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium
    Melissa L Bondy
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:1953-68. 2008
    ..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address...
  57. ncbi request reprint Ethnic differences in survival among women with ovarian carcinoma
    Jill S Barnholtz-Sloan
    Epidemiology Section, Population Studies and Prevention Program, Karmanos Cancer Institute, Detroit, Michigan 48201, USA
    Cancer 94:1886-93. 2002
    ..The objective of this study was to examine ethnic differences in survival after ovarian carcinoma in a population-based sample of women...
  58. ncbi request reprint Admixture effects in the traditional linkage analysis of admixed families
    Jill S Barnholtz-Sloan
    Karmanos Cancer Institute, Population Studies and Prevention Program, Wayne State University, Detroit, Michigan 48201, USA
    Ethn Dis 12:411-9. 2002
    ..If one or both of these assumptions are violated, incorrect inference for linkage could result...
  59. pmc Analysis of gene x environment interactions in sibships using mixed models
    Jill S Barnholtz-Sloan
    Department of Internal Medicine Oncology, Wayne State University School of Medicine and Karmanos Cancer Institute, 110 East Warren, Detroit, Michigan, USA
    BMC Genet 4:S18. 2003
    ....
  60. ncbi request reprint Examining population stratification via individual ancestry estimates versus self-reported race
    Jill S Barnholtz-Sloan
    Cancer Prevention and Control Program, H Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, Florida 33612, USA
    Cancer Epidemiol Biomarkers Prev 14:1545-51. 2005
    ..This study suggests that significant population substructure differences exist that self-reported race alone does not capture and that individual ancestry may be confounded with disease status and/or a candidate gene risk genotype...
  61. ncbi request reprint Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System
    Jill S Barnholtz-Sloan
    Karmanos Cancer Institute, Wayne State University School of Medicine, 110 E Warren, Detroit, MI 48201, USA
    J Clin Oncol 22:2865-72. 2004
    ..The purpose of this study was to calculate population-based incidence proportions (IPs) of brain metastases from single primary lung, melanoma, breast, renal, or colorectal cancer...
  62. ncbi request reprint Survival of women diagnosed with malignant, mixed mullerian tumors of the ovary (OMMMT)
    Jill S Barnholtz-Sloan
    Division of Hematology Oncology, Department of Internal Medicine, Wayne State University School of Medicine and Karmanos Cancer Institute, Detroit, MI 48201, USA
    Gynecol Oncol 93:506-12. 2004
    ..To analyze the survival of women with malignant, mixed mullerian tumors of the ovary (OMMMT) compared to women with epithelial ovarian cancer (EOC)...
  63. pmc Susceptibility scoring in family-based association testing
    Laila M Poisson
    Department of Biostatistics and Research Epidemiology, Henry Ford Health Sciences Center, Detroit, Michigan, USA
    BMC Genet 4:S49. 2003
    ..Tests are available to include multiple siblings, unaffected offspring, and to adjust for environmental covariates. We explore a susceptibility residual method of adjustment for covariates...
  64. doi request reprint Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology Consortium
    Faith G Davis
    Division of Epidemiology Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA
    Cancer Epidemiol Biomarkers Prev 17:484-9. 2008
    ..It is essential that epidemiologists and neuropathologists collaborate to develop appropriate study designs and protocols for specific hypothesis and populations...

Research Grants1

  1. Analysis of Ethnic Admixture in Lung Cancer
    Jill Barnholtz Sloan; Fiscal Year: 2006
    ..These projects will give me experience in developing methodology in statistical genetics and genetic epidemiology, while also helping me to better understand etiology of disease. ..