Robert M Hazen
Affiliation: Carnegie Institution of Washington
- Chiral selection on inorganic crystalline surfacesRobert M Hazen
Carnegie Institution of Washington and NASA Astrobiology Institute, 5251 Broad Branch Road NW, Washington DC 20015, USA
Nat Mater 2:367-74. 2003..Here we review experimental and theoretical approaches to chiral selection on inorganic crystalline surfaces - research that is poised to open this new frontier in understanding and exploiting surface-molecule interactions...
- Microbial activity at gigapascal pressuresAnurag Sharma
Geophysical Laboratory, Carnegie Institution of Washington, 5251 Broad Branch Road, N W, Washington, DC 20015, USA
Science 295:1514-6. 2002..1 MPa). Evidence of microbial viability and activity at these extreme pressures expands by an order of magnitude the range of conditions representing the habitable zone in the solar system...
- Adsorption of nucleic acid components on rutile (TiO(2)) surfacesH James Cleaves
Geophysical Laboratory, Carnegie Institution of Washington, 5251 Broad Branch Rd NW, Washington, DC 20015, USA
Astrobiology 10:311-23. 2010..The conformations of the molecules bound to rutile surfaces appear to favor specific interactions, which in turn may allow identification of the most favorable mineral surfaces for nucleic acid adsorption...
- Attachment of L-glutamate to rutile (alpha-TiO(2)): a potentiometric, adsorption, and surface complexation studyCaroline M Jonsson
Department of Earth and Planetary Sciences, Johns Hopkins University, Baltimore, Maryland 21218, USA
Langmuir 25:12127-35. 2009..Overall, our results serve as a basis for a better quantitative understanding of how and under what conditions acidic amino acids bind to oxide mineral surfaces...
- The emergence of patterning in lifes origin and evolutionRobert M Hazen
Carnegie Institution, Washington, DC 20015, USA
Int J Dev Biol 53:683-92. 2009....
- Mineral surfaces, geochemical complexities, and the origins of lifeRobert M Hazen
Geophysical Laboratory, Carnegie Institution of Washington, Washington, DC 20015, USA
Cold Spring Harb Perspect Biol 2:a002162. 2010..Thus, mineral surfaces may have contributed centrally to the linked prebiotic problems of containment and organization by promoting the transition from a dilute prebiotic "soup" to highly ordered local domains of key biomolecules...
- Functional information and the emergence of biocomplexityRobert M Hazen
Geophysical Laboratory, Carnegie Institution, 5251 Broad Branch Road NW, Washington, DC 20015 1305, USA
Proc Natl Acad Sci U S A 104:8574-81. 2007..In each case we observe evidence for several distinct solutions with different maximum degrees of function, features that lead to steps in plots of information versus degree of function...
- Hydrothermal reactions of pyruvic acid: synthesis, selection, and self-assembly of amphiphilic moleculesRobert M Hazen
Carnegie Institution and NASA Astrobiology Institute, 5251 Broad Branch Road NW, Washington, DC 20015 1305, USA
Orig Life Evol Biosph 37:143-52. 2007..These results suggest that a robust family of prebiotic reaction pathways produces similar products over a range of geochemical and astrochemical environments...
- The first contribution of capillary electrophoresis to the study of abiotic origins of homochirality: investigation of the enantioselective adsorption of 3-carboxy adipic acid on mineralsMaría Castro-Puyana
Department of Analytical Chemistry, Faculty of Chemistry, University of Alcala, Alcala de Henares, Madrid, Spain
Electrophoresis 29:1548-55. 2008..Results showed that an enantioselective adsorption of the enantiomers of 3-carboxy adipic acid on minerals took place...
- Debating evidence for the origin of life on EarthJeffrey L Bada
Science 315:937-9; author reply 937-9. 2007
- Sequence analysis of trimer isomers formed by montmorillonite catalysis in the reaction of binary monomer mixturesGözen Ertem
Geophysical Laboratory and NASA Astrobiology Institute, Washington, DC, USA
Astrobiology 7:715-22. 2007..These results lend support to Bernal's hypothesis that minerals may have played a significant role in the chemical processes that led to the origin of life by catalyzing the formation of phosphodiester bonds in RNA-like oligomers...