John Doyle

Summary

Affiliation: California Institute of Technology
Country: USA

Publications

  1. doi request reprint Even Noisy Responses Can Be Perfect If Integrated Properly
    John C Doyle
    Computing and Mathematical Sciences, Electrical Engineering, and Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA Electronic address
    Cell Syst 2:73-5. 2016
  2. ncbi request reprint Bow ties, metabolism and disease
    Marie Csete
    Emory Anesthiology Research Labs, 1462 Clifton Rd NE, Room 420, Atlanta GA 30322, USA
    Trends Biotechnol 22:446-50. 2004
  3. pmc Motifs, control, and stability
    John Doyle
    Department of Control and Dynamical Systems, California Institute of Technology, Pasadena, California, United States of America
    PLoS Biol 3:e392. 2005
  4. pmc MathSBML: a package for manipulating SBML-based biological models
    Bruce E Shapiro
    Jet Propulsion Laboratory, California Institute of Technology, Mail Stop 126 347, 4800 Oak Grove Drive, Pasadena, CA 91109, USA
    Bioinformatics 20:2829-31. 2004
  5. ncbi request reprint Rules of engagement
    John Doyle
    California Institute of Technology, Pasadena, California 91125 8100, USA
    Nature 446:860. 2007
  6. pmc Wildfires, complexity, and highly optimized tolerance
    Max A Moritz
    Department of Environmental Science, Policy, and Management, University of California, Berkeley, 94720, USA
    Proc Natl Acad Sci U S A 102:17912-7. 2005
  7. ncbi request reprint Some protein interaction data do not exhibit power law statistics
    Reiko Tanaka
    Bio Mimetic Control Research Center, RIKEN, Nagoya 223 8522, Japan
    FEBS Lett 579:5140-4. 2005
  8. ncbi request reprint Metabolic syndrome and robustness tradeoffs
    Hiroaki Kitano
    Sony Computer Science Laboratories, Inc 3 14 13, Higashi Gotanda, Shinagawa, Tokyo 141 0022 Japan
    Diabetes 53:S6-S15. 2004
  9. ncbi request reprint Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration
    Herbert M Sauro
    Keck Graduate Institute, Claremont, California 91711, USA
    OMICS 7:355-72. 2003
  10. pmc Mutation, specialization, and hypersensitivity in highly optimized tolerance
    Tong Zhou
    Department of Physics, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 99:2049-54. 2002

Collaborators

Detail Information

Publications10

  1. doi request reprint Even Noisy Responses Can Be Perfect If Integrated Properly
    John C Doyle
    Computing and Mathematical Sciences, Electrical Engineering, and Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA Electronic address
    Cell Syst 2:73-5. 2016
    ..Integral feedback for perfect adaptation is a ubiquitous strategy in engineering and biology. Long studied in deterministic settings, it can now be understood in the context of the fully stochastic systems that are prevalent in biology. ..
  2. ncbi request reprint Bow ties, metabolism and disease
    Marie Csete
    Emory Anesthiology Research Labs, 1462 Clifton Rd NE, Room 420, Atlanta GA 30322, USA
    Trends Biotechnol 22:446-50. 2004
    ..Large-scale organizational frameworks such as the bow tie are necessary starting points for higher-resolution modeling of complex biologic processes..
  3. pmc Motifs, control, and stability
    John Doyle
    Department of Control and Dynamical Systems, California Institute of Technology, Pasadena, California, United States of America
    PLoS Biol 3:e392. 2005
  4. pmc MathSBML: a package for manipulating SBML-based biological models
    Bruce E Shapiro
    Jet Propulsion Laboratory, California Institute of Technology, Mail Stop 126 347, 4800 Oak Grove Drive, Pasadena, CA 91109, USA
    Bioinformatics 20:2829-31. 2004
    ..By accessing the full breadth of Mathematica functionality, MathSBML is fully extensible to SBML models of any size or complexity...
  5. ncbi request reprint Rules of engagement
    John Doyle
    California Institute of Technology, Pasadena, California 91125 8100, USA
    Nature 446:860. 2007
  6. pmc Wildfires, complexity, and highly optimized tolerance
    Max A Moritz
    Department of Environmental Science, Policy, and Management, University of California, Berkeley, 94720, USA
    Proc Natl Acad Sci U S A 102:17912-7. 2005
    ..Understanding these mechanisms may provide new insights into the structure of ecological systems and be key in evaluating fire management strategies and sensitivities to climate change...
  7. ncbi request reprint Some protein interaction data do not exhibit power law statistics
    Reiko Tanaka
    Bio Mimetic Control Research Center, RIKEN, Nagoya 223 8522, Japan
    FEBS Lett 579:5140-4. 2005
    ..We explain the source of this error using numerically generated data from analytic formulas, where there are no sampling or noise ambiguities...
  8. ncbi request reprint Metabolic syndrome and robustness tradeoffs
    Hiroaki Kitano
    Sony Computer Science Laboratories, Inc 3 14 13, Higashi Gotanda, Shinagawa, Tokyo 141 0022 Japan
    Diabetes 53:S6-S15. 2004
    ..A detailed molecular interaction map for adipocyte, hepatocyte, skeletal muscle cell, and pancreatic beta-cell cross-talk in the metabolic syndrome can be viewed at http://www.systems-biology.org/001/003.html...
  9. ncbi request reprint Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration
    Herbert M Sauro
    Keck Graduate Institute, Claremont, California 91711, USA
    OMICS 7:355-72. 2003
    ....
  10. pmc Mutation, specialization, and hypersensitivity in highly optimized tolerance
    Tong Zhou
    Department of Physics, University of California, Santa Barbara, CA 93106, USA
    Proc Natl Acad Sci U S A 99:2049-54. 2002
    ..Although the model is a severe abstraction of biology, it produces a surprisingly wide variety of micro- and macroevolutionary features strikingly similar to real biological evolution...