Affiliation: Brigham Young University
- Recombination estimation under complex evolutionary models with the coalescent composite-likelihood methodAntonio Carvajal-Rodriguez
Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah, USA
Mol Biol Evol 23:817-27. 2006..In such cases, the use of more complex models slightly increases performance in some occasions, especially in the case of the LPT. Thus, our results provide for a more robust application of the estimation of recombination rates...
- Recombination favors the evolution of drug resistance in HIV-1 during antiretroviral therapyAntonio Carvajal-Rodriguez
Department of Microbiology and Molecular Biology, Brigham Young University, 84602 Provo, UT, USA
Infect Genet Evol 7:476-83. 2007..Our results suggest that recombination plays an important role in the evolution of drug resistance in HIV-1 under various realistic scenarios. These findings could be taken into account in order to develop optimal HIV-1 drug treatments...
- Disease progression and evolution of the HIV-1 env gene in 24 infected infantsAntonio Carvajal-Rodriguez
Department of Biology, Brigham Young University, 84602 Provo, UT, USA
Infect Genet Evol 8:110-20. 2008..Overall, the results obtained confirm that viral adaptation in the C2V3C3 region of the env gene is related to disease progression, although the statistical characterization of such pattern seems rather difficult...
- JMATING: a software for the analysis of sexual selection and sexual isolation effects from mating frequency dataAntonio Carvajal-Rodriguez
Department of Microbiology and Molecular Biology, Brigham Young University, Provo, Utah 84602, USA
BMC Evol Biol 6:40. 2006..However, there is no available software that implements all these statistical estimators and their corresponding tests for the study of mating behaviour...