- ClC chloride channelsJ A Mindell
Howard Hughes Medical Institute and Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA
Genome Biol 2:REVIEWS3003. 2001..The medical importance of ClC channels - four inherited diseases have been blamed on familial ClC dysfunction to date - highlights their diverse physiological functions and provides strong motivation for further study...
- Projection structure of a ClC-type chloride channel at 6.5 A resolutionJ A Mindell
Department of Biochemistry, Howard Hughes Medical Institute, Basic Medical Science Research Center, Brandeis University, Waltham, Massachusetts 02454, USA
Nature 409:219-23. 2001..Cryo-electron microscopic analysis of these crystals yields a projection structure at 6.5 A resolution, which shows off-axis water-filled pores within the dimeric channel complex...
- A decade of CLC chloride channels: structure, mechanism, and many unsettled questionsM Maduke
Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02454, USA
Annu Rev Biophys Biomol Struct 29:411-38. 2000..New approaches, including structural analyses, will be crucial to an understanding of ClC architecture and function...