James Z Chen

Summary

Affiliation: Brandeis University
Country: USA

Publications

  1. ncbi request reprint SIGNATURE: a single-particle selection system for molecular electron microscopy
    James Z Chen
    Howard Hughes Medical Institute, W M Keck Institute for Cellular Visualization, Department of Biochemistry, Brandeis University, Waltham, MA 22454 9110, USA
    J Struct Biol 157:168-73. 2007
  2. pmc A dose-rate effect in single-particle electron microscopy
    James Z Chen
    Howard Hughes Medical Institute, Rosenstiel Center MS029, Brandeis University, 415 South Street, Waltham, MA 02545 9110, USA
    J Struct Biol 161:92-100. 2008
  3. pmc Beam-induced motion of vitrified specimen on holey carbon film
    Axel F Brilot
    Department of Biochemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, MS029, 415 South Street, Waltham, MA 02454, USA
    J Struct Biol 177:630-7. 2012
  4. pmc Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM
    James Z Chen
    Rosenstiel Basic Medical Research Center, Brandeis University, Waltham, MA 02454, USA
    Proc Natl Acad Sci U S A 106:10644-8. 2009
  5. pmc High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus
    Carsten Sachse
    Howard Hughes Medical Institute, Brandeis University MS029, 415 South Street, Waltham, MA 02454, USA
    J Mol Biol 371:812-35. 2007
  6. ncbi request reprint Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism
    Fadel A Samatey
    Dynamic NanoMachine Project, ICORP, JST, 1 3 Yamadaoka, Suita, Osaka 565 0871, Japan
    Nature 431:1062-8. 2004

Collaborators

Detail Information

Publications6

  1. ncbi request reprint SIGNATURE: a single-particle selection system for molecular electron microscopy
    James Z Chen
    Howard Hughes Medical Institute, W M Keck Institute for Cellular Visualization, Department of Biochemistry, Brandeis University, Waltham, MA 22454 9110, USA
    J Struct Biol 157:168-73. 2007
    ..The system design emphasizes both functionality and usability. This software has been released to the EM community and has been successfully applied to macromolecular structural analyses...
  2. pmc A dose-rate effect in single-particle electron microscopy
    James Z Chen
    Howard Hughes Medical Institute, Rosenstiel Center MS029, Brandeis University, 415 South Street, Waltham, MA 02545 9110, USA
    J Struct Biol 161:92-100. 2008
    ..The improvement in image quality, especially for multiple-exposure data collection, will help single-particle cryo-EM to reach higher resolution...
  3. pmc Beam-induced motion of vitrified specimen on holey carbon film
    Axel F Brilot
    Department of Biochemistry, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, MS029, 415 South Street, Waltham, MA 02454, USA
    J Struct Biol 177:630-7. 2012
    ..We show how alignment and averaging of movie frames can be used to restore high-resolution detail in images affected by beam-induced motion...
  4. pmc Molecular interactions in rotavirus assembly and uncoating seen by high-resolution cryo-EM
    James Z Chen
    Rosenstiel Basic Medical Research Center, Brandeis University, Waltham, MA 02454, USA
    Proc Natl Acad Sci U S A 106:10644-8. 2009
    ..The Ca(2+)-stabilized VP7 intratrimer contact region, which presents important neutralizing epitopes, is unaltered upon capsid binding...
  5. pmc High-resolution electron microscopy of helical specimens: a fresh look at tobacco mosaic virus
    Carsten Sachse
    Howard Hughes Medical Institute, Brandeis University MS029, 415 South Street, Waltham, MA 02454, USA
    J Mol Biol 371:812-35. 2007
    ..Overall, the observed differences suggest that the new model represents a different, more stable state of the virus, compared with the earlier published model...
  6. ncbi request reprint Structure of the bacterial flagellar hook and implication for the molecular universal joint mechanism
    Fadel A Samatey
    Dynamic NanoMachine Project, ICORP, JST, 1 3 Yamadaoka, Suita, Osaka 565 0871, Japan
    Nature 431:1062-8. 2004
    ..The model reveals the intricate molecular interactions and a plausible switching mechanism for the hook to be flexible in bending but rigid against twisting for its universal joint function...