Affiliation: Boston University
- Genetic and epigenetic aspects of breast cancer progression and therapyShannon Byler
Cancer Center, L913, Department of Medicine, Boston University School of Medicine, 72 E Concord St, Boston, MA 02118, U S A
Anticancer Res 34:1071-7. 2014..Overall, breast cancer subtypes may have a similar epigenetic signal that promotes cancer development, and treatment may be most effective if both epigenetic and genetic differences are targeted. ..
- Cancer development, progression, and therapy: an epigenetic overviewSibaji Sarkar
Cancer Center, L913, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, Boston, MA 02118, USA
Int J Mol Sci 14:21087-113. 2013..Adopting epigenetic alteration as a new hallmark of cancer is a logical and necessary step that will further encourage the development of novel epigenetic biomarkers and therapeutics. ..
- Demethylation and re-expression of epigenetically silenced tumor suppressor genes: sensitization of cancer cells by combination therapySibaji Sarkar
Cancer Center, Boston University School of Medicine, Boston, MA 02118, USA
Epigenomics 5:87-94. 2013..In particular, we will consider how a combination therapy that includes epigenetic drugs could possibly kill cancer progenitor cells and reduce the chance of relapse following chemotherapy...
- Anti-breast cancer effects of histone deacetylase inhibitors and calpain inhibitorMegan A Mataga
Cancer Center, Boston University School of Medicine, 72 East Concord Street, L 913, Boston, MA 02118, USA
Anticancer Res 32:2523-9. 2012....
- MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expressionKripa Patel
Cancer Center, Boston University School of Medicine, Boston, MA, United States
Cancer Lett 347:54-64. 2014..Our study thus identified a mechanism by which STAT3 signaling can be inhibited in pancreatic cancer cells by modifying let-7 expression. ..
- Enhanced cytotoxicity from deoxyguanosine-enriched T-oligo in prostate cancer cellsAndrew M Rankin
Cancer Center and Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA
Nucleic Acid Ther 23:311-21. 2013....