Chad L Mayer

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals
    Chad L Mayer
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Toxins (Basel) 4:1261-87. 2012
  2. pmc Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns
    Chad L Mayer
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA
    Front Immunol 6:155. 2015
  3. pmc Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury
    Caitlin S L Parello
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, 670 Albany Street, Boston, MA 02118, USA
    Toxins (Basel) 7:170-86. 2015
  4. pmc Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy
    Benjamin C Lee
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Blood 122:803-6. 2013

Collaborators

Detail Information

Publications4

  1. pmc Shiga toxins and the pathophysiology of hemolytic uremic syndrome in humans and animals
    Chad L Mayer
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Toxins (Basel) 4:1261-87. 2012
    ..The emergence of new strains with rapidly aggressive virulence makes clinical and research initiatives in this field a high public health priority...
  2. pmc Pro-Coagulant Endothelial Dysfunction Results from EHEC Shiga Toxins and Host Damage-Associated Molecular Patterns
    Chad L Mayer
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA, USA
    Front Immunol 6:155. 2015
    ..Together, these data suggest a potential role Stx to produce DAMPs, and DAMPs to produce endothelial injury and a pro-thrombotic environment...
  3. pmc Shiga toxin 2-induced endoplasmic reticulum stress is minimized by activated protein C but does not correlate with lethal kidney injury
    Caitlin S L Parello
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, 670 Albany Street, Boston, MA 02118, USA
    Toxins (Basel) 7:170-86. 2015
    ..These data indicate that Stx2 induces renal ER stress and apoptosis in murine models of Stx2-induced kidney injury, but decreasing these processes alone was not sufficient to alter survival outcome. ..
  4. pmc Quiescent complement in nonhuman primates during E coli Shiga toxin-induced hemolytic uremic syndrome and thrombotic microangiopathy
    Benjamin C Lee
    Department of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, MA 02118, USA
    Blood 122:803-6. 2013
    ....