M W Logue

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
    Badri Vardarajan
    Department of Medicine Biomedical Genetics, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Mol Neurodegener 8:10. 2013
  2. pmc Using linkage analysis of large pedigrees to guide association analyses
    Seung Hoan Choi
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Proc 5:S79. 2011
  3. pmc Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families
    Mark W Logue
    Biomedical Genetics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Med Genet B Neuropsychiatr Genet 159:274-80. 2012
  4. doi request reprint Computation of the posterior probability of linkage using 'high effect' genetic model priors
    M W Logue
    Genetics Program, Boston University School of Medicine, 715 Albany St L320D, Boston, MA 02118, USA
    Hum Hered 66:25-34. 2008
  5. pmc Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, USA
    Hum Hered 57:10-20. 2004
  6. ncbi request reprint A new method for computing the multipoint posterior probability of linkage
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Hum Hered 57:90-9. 2004
  7. ncbi request reprint The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker
    Xinqun Yang
    Center for Statistical Genetics Research, The University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 59:210-9. 2005
  8. ncbi request reprint Model selection and Bayesian methods in statistical genetics: summary of group 11 contributions to Genetic Analysis Workshop 15
    Michael D Swartz
    Department of Epidemiology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Genet Epidemiol 31:S96-102. 2007
  9. ncbi request reprint The incorporation of prior genomic information does not necessarily improve the performance of Bayesian linkage methods: an example involving sex-specific recombination and the two-point PPL
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 60:196-205. 2005
  10. pmc A model-integrated multipoint Bayesian analysis of hypertension in the Framingham Heart Study data finds little evidence of linkage
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 4:S75. 2003

Collaborators

Detail Information

Publications12

  1. pmc Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts
    Badri Vardarajan
    Department of Medicine Biomedical Genetics, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Mol Neurodegener 8:10. 2013
    ..Here, we reevaluated tau pathologies in the same TgCRND8 mouse model as the previous studies...
  2. pmc Using linkage analysis of large pedigrees to guide association analyses
    Seung Hoan Choi
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue, Boston, MA 02118, USA
    BMC Proc 5:S79. 2011
    ..5% of the exome. This result suggests that incorporating linkage results from large multiplex families might greatly increase the efficiency of sequencing to detect trait-associated alleles in complex disease...
  3. pmc Multivariate analysis of anxiety disorders yields further evidence of linkage to chromosomes 4q21 and 7p in panic disorder families
    Mark W Logue
    Biomedical Genetics, Boston University School of Medicine, Boston, Massachusetts 02118, USA
    Am J Med Genet B Neuropsychiatr Genet 159:274-80. 2012
    ..More generally, this suggests that analyses including multiple aspects of psychopathology may lead to greater consistency across datasets...
  4. doi request reprint Computation of the posterior probability of linkage using 'high effect' genetic model priors
    M W Logue
    Genetics Program, Boston University School of Medicine, 715 Albany St L320D, Boston, MA 02118, USA
    Hum Hered 66:25-34. 2008
    ..However, much of the parameter space corresponds to models that seem unlikely to yield substantial evidence for linkage: for example, models with very high phenocopy rates...
  5. pmc Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ, USA
    Hum Hered 57:10-20. 2004
    ..2003). Our results indicate that using samples selected for components of the autism phenotype may be a useful adjunct to autism genetics...
  6. ncbi request reprint A new method for computing the multipoint posterior probability of linkage
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    Hum Hered 57:90-9. 2004
    ..This version, which we call the imputed PPL, is shown to be superior to previously developed versions...
  7. ncbi request reprint The posterior probability of linkage allowing for linkage disequilibrium and a new estimate of disequilibrium between a trait and a marker
    Xinqun Yang
    Center for Statistical Genetics Research, The University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 59:210-9. 2005
    ..The estimate of D' also behaves well even in relatively small, heterogeneous samples...
  8. ncbi request reprint Model selection and Bayesian methods in statistical genetics: summary of group 11 contributions to Genetic Analysis Workshop 15
    Michael D Swartz
    Department of Epidemiology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Genet Epidemiol 31:S96-102. 2007
    ..These group contributions exhibit the value of framing genetic problems in terms of model selection, and highlight the impact of variable selection for gene mapping...
  9. ncbi request reprint The incorporation of prior genomic information does not necessarily improve the performance of Bayesian linkage methods: an example involving sex-specific recombination and the two-point PPL
    Mark W Logue
    Program in Public Health Genetics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Hum Hered 60:196-205. 2005
    ..We present a two-point PPL allowing for unequal male and female recombination fractions, thetaM and thetaF, and consider alternative priors on thetaM, thetaF...
  10. pmc A model-integrated multipoint Bayesian analysis of hypertension in the Framingham Heart Study data finds little evidence of linkage
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa, USA
    BMC Genet 4:S75. 2003
    ..While the PPL analysis of this data remains inconclusive, Bayesian methodology gives us a clear mechanism for using the information gained here in further studies...
  11. ncbi request reprint Bayesian analysis of a previously published genome screen for panic disorder reveals new and compelling evidence for linkage to chromosome 7
    Mark W Logue
    Division of Statistical Genetics, Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    Am J Med Genet B Neuropsychiatr Genet 121:95-9. 2003
    ..The results for the remainder of the genome are consistently low. The two loci identified here are also supported by independent evidence from other studies...
  12. pmc A major susceptibility locus for specific language impairment is located on 13q21
    Christopher W Bartlett
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Piscataway, NJ 08854 8095, USA
    Am J Hum Genet 71:45-55. 2002
    ..86, genomic P value <.06 under the recessive language impairment model). Our findings underscore the utility of traditional LOD-score-based methods in finding genes for complex diseases, specifically, SLI...