Ching Ti Liu

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin
    Ching Ti Liu
    Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA Electronic address
    Am J Hum Genet 99:56-75. 2016
  2. pmc Multi-ethnic fine-mapping of 14 central adiposity loci
    Ching Ti Liu
    Department of Biostatistics, Boston University, Boston, MA, USA
    Hum Mol Genet 23:4738-44. 2014
  3. pmc Comparison of statistical approaches to rare variant analysis for quantitative traits
    Han Chen
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Proc 5:S113. 2011
  4. pmc Assessment of gene-by-sex interaction effect on bone mineral density
    Ching Ti Liu
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston, MA 02118, USA
    J Bone Miner Res 27:2051-64. 2012
  5. pmc Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study
    Ching Ti Liu
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    J Bone Miner Res 27:954-8. 2012
  6. pmc Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies
    Alisa K Manning
    School of Public Health, Boston University, 715 Albany Street, Boston, Massachusetts 02118, USA
    BMC Proc 3:S81. 2009
  7. pmc Visceral Adipose Tissue Is Associated With Bone Microarchitecture in the Framingham Osteoporosis Study
    Ching Ti Liu
    Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA
    J Bone Miner Res 32:143-150. 2017
  8. doi request reprint Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study
    Yi Hsiang Hsu
    The Institute for Aging Research Hebrew SeniorLife and the Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Hum Mol Genet . 2016
  9. pmc Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies
    Jaeyoung Hong
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    Genet Epidemiol 40:284-92. 2016
  10. pmc Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
    Soo Lim
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 229:149-54. 2013

Detail Information

Publications12

  1. pmc Trans-ethnic Meta-analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucose and Insulin
    Ching Ti Liu
    Department of Biostatistics, School of Public Health, Boston University, Boston, MA 02118, USA Electronic address
    Am J Hum Genet 99:56-75. 2016
    ....
  2. pmc Multi-ethnic fine-mapping of 14 central adiposity loci
    Ching Ti Liu
    Department of Biostatistics, Boston University, Boston, MA, USA
    Hum Mol Genet 23:4738-44. 2014
    ..We annotated variants using information from the ENCODE Consortium and Roadmap Epigenomics Project to prioritize variants for possible functionality...
  3. pmc Comparison of statistical approaches to rare variant analysis for quantitative traits
    Han Chen
    Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA
    BMC Proc 5:S113. 2011
    ....
  4. pmc Assessment of gene-by-sex interaction effect on bone mineral density
    Ching Ti Liu
    Department of Biostatistics, Boston University School of Public Health, 801 Massachusetts Avenue CT3, Boston, MA 02118, USA
    J Bone Miner Res 27:2051-64. 2012
    ..If they exist, gene-by-sex interactions for BMD probably have weak effects, accounting for less than 0.08% of the variation in these traits per implicated SNP. © 2012 American Society for Bone and Mineral Research...
  5. pmc Heritability of prevalent vertebral fracture and volumetric bone mineral density and geometry at the lumbar spine in three generations of the Framingham study
    Ching Ti Liu
    Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA
    J Bone Miner Res 27:954-8. 2012
    ....
  6. pmc Incorporating biological knowledge in the search for gene x gene interaction in genome-wide association studies
    Alisa K Manning
    School of Public Health, Boston University, 715 Albany Street, Boston, Massachusetts 02118, USA
    BMC Proc 3:S81. 2009
    ..012)...
  7. pmc Visceral Adipose Tissue Is Associated With Bone Microarchitecture in the Framingham Osteoporosis Study
    Ching Ti Liu
    Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA
    J Bone Miner Res 32:143-150. 2017
    ..2016 American Society for Bone and Mineral Research...
  8. doi request reprint Targeted sequencing of genome wide significant loci associated with bone mineral density (BMD) reveals significant novel and rare variants: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) targeted sequencing study
    Yi Hsiang Hsu
    The Institute for Aging Research Hebrew SeniorLife and the Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Hum Mol Genet . 2016
    ..We performed fine-mapping by targeted sequencing at WLS, MEF2C, ARHGAP1/F2 and JAG1 loci prioritized by eQTL and bioinformatic approaches among 56 BMD loci from our previous GWAS meta-analysis...
  9. pmc Evaluation of a Two-Stage Approach in Trans-Ethnic Meta-Analysis in Genome-Wide Association Studies
    Jaeyoung Hong
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, United States of America
    Genet Epidemiol 40:284-92. 2016
    ..These results suggest that prior clustering in the two-stage approach can be an effective and efficient intermediate step in meta-analysis to account for the multiethnic heterogeneity. ..
  10. pmc Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
    Soo Lim
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 229:149-54. 2013
    ..We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits...
  11. pmc Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
    Geoffrey A Walford
    Diabetes Research Center Diabetes Unit, Massachusetts General Hospital, Boston, MA Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA Department of Medicine, Harvard Medical School, Boston, MA
    Diabetes 65:3200-11. 2016
    ..In conclusion, we identified two novel loci and replicated known variants associated with insulin sensitivity. Further studies are needed to clarify the causal variant and function at the BCL2 and FAM19A2 loci. ..
  12. doi request reprint Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
    Carrie M Nielson
    School of Public Health, Oregon Health and Science University, Portland, OR, USA
    J Bone Miner Res 31:2085-2097. 2016
    ..These results may help elucidate vertebral bone biology and novel approaches to reducing vertebral fracture incidence. © 2016 American Society for Bone and Mineral Research...