Karl C K Kuban
Affiliation: Boston University School of Medicine
- The breadth and type of systemic inflammation and the risk of adverse neurological outcomes in extremely low gestation newbornsKarl C K Kuban
Department of Pediatrics, Boston Medical Center, Boston, Massachusetts Electronic address
Pediatr Neurol 52:42-8. 2015....
- Systemic inflammation and cerebral palsy risk in extremely preterm infantsKarl C K Kuban
Department of Pediatrics, Boston Medical Center, Boston, MA, USA
J Child Neurol 29:1692-8. 2014..Repeated elevations of inflammation-related proteins during the first 2 postnatal weeks are associated with increased risk of cerebral palsy. ..
- Positive screening on the Modified Checklist for Autism in Toddlers (M-CHAT) in extremely low gestational age newbornsKarl C K Kuban
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA 02118, USA
J Pediatr 154:535-540.e1. 2009..To test the hypothesis that children born preterm are more likely to screen positive on the M-CHAT for an autism spectrum disorder...
- Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational ageKarl C K Kuban
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, Massachusetts, USA
J Child Neurol 24:63-72. 2009..Nearly half the cerebral palsy identified at 2 years is not preceded by a neonatal brain ultrasound abnormality...
- An algorithm for identifying and classifying cerebral palsy in young childrenKarl C K Kuban
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
J Pediatr 153:466-72. 2008....
- Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic studyKarl C K Kuban
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, MA 02118, USA
J Child Neurol 20:829-31. 2005..It provides an effective means to evaluate interobserver variability, offers a route for feedback, and creates an opportunity to reevaluate variability, both immediately and at periodic intervals...
- Developmental correlates of head circumference at birth and two years in a cohort of extremely low gestational age newbornsKarl C K Kuban
Division of Pediatric Neurology, Department of Pediatrics, Boston Medical Center, Boston University, Boston, MA, USA
J Pediatr 155:344-9.e1-3. 2009..To evaluate the developmental correlates of microcephaly evident at birth and at 2 years in a cohort born at extremely low gestational age...
- The Modified Checklist for Autism in Toddlers in extremely low gestational age newborns: individual items associated with motor, cognitive, vision and hearing limitationsRHIANNON J LUYSTER
Laboratories of Cognitive Neuroscience, Division of Developmental Medicine, Harvard Medical School, Boston, MA 02215, USA
Paediatr Perinat Epidemiol 25:366-76. 2011..The strong association between impaired sensory or motor function and M-CHAT results among extremely low gestational age children suggests that such impairments might give rise to false positive M-CHAT screening...
- Inflammation-initiating illnesses, inflammation-related proteins, and cognitive impairment in extremely preterm infantsT MICHAEL O'SHEA
Division of Neonatology, Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
Brain Behav Immun 29:104-12. 2013..We conclude that elevated blood concentrations of inflammation-related proteins provide information about the risk of impaired cognitive function at age 2 years that supplements information provided by inflammation-associated illnesses...
- Systemic inflammation, intraventricular hemorrhage, and white matter injuryAlan Leviton
1Department of Neurology, Children s Hospital, Boston, MA, USA
J Child Neurol 28:1637-45. 2013..Each entity is associated with inflammation, but the combination has a stronger inflammatory signal than hemorrhage alone. ..
- Neonatal cranial ultrasound lesions and developmental delays at 2 years of age among extremely low gestational age childrenT MICHAEL O'SHEA
Wake Forest University Health Sciences, Department of Pediatrics, Medical Center Boulevard, Winston Salem, NC 27157, USA
Pediatrics 122:e662-9. 2008..Studies of the relationship between ultrasound images from preterm newborns and developmental delay most often are based on small samples defined by birth weight and exclude infants not testable with standardized assessments...
- SNAP-II and SNAPPE-II and the risk of structural and functional brain disorders in extremely low gestational age newborns: the ELGAN studyOlaf Dammann
Division of Newborn Medicine, Floating Hospital for Children at Tufts Medical Center, Boston, Mass 02111, USA
Neonatology 97:71-82. 2010..Illness severity measures predict death and illnesses in the newborn. It is unknown how well they predict brain lesions evident on ultrasound scans or neurodevelopmental dysfunctions in preterm infants...
- Early blood gas abnormalities and the preterm brainAlan Leviton
Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
Am J Epidemiol 172:907-16. 2010..Findings suggest that individual blood gas derangements do not increase brain damage risk. Rather, the multiple derangements associated with indicators of brain damage might be indicators of immaturity/vulnerability and illness severity...
- Blood protein concentrations in the first two postnatal weeks associated with early postnatal blood gas derangements among infants born before the 28th week of gestation. The ELGAN StudyAlan Leviton
Department of Neurology, Children s Hospital Boston, and Harvard Medical School, Boston, MA 02115, USA
Cytokine 56:392-8. 2011..To explore the relationships between blood gas derangements and blood concentrations of inflammation-related proteins shortly after preterm birth...
- Elevated concentrations of inflammation-related proteins in postnatal blood predict severe developmental delay at 2 years of age in extremely preterm infantsT MICHAEL O'SHEA
Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
J Pediatr 160:395-401.e4. 2012..To evaluate the hypothesis that elevated levels of inflammation-related proteins in early postnatal blood predict impaired mental and motor development in extremely preterm infants...
- The clustering of disorders in infants born before the 28th week of gestationAlan Leviton
Neurology Department, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Acta Paediatr 99:1795-800. 2010..To see whether disorders prevalent in infants born extremely preterm cluster...
- Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?Linda J Van Marter
Newborn Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Arch Dis Child Fetal Neonatal Ed 96:F20-9. 2011..To evaluate the relationships among cerebral palsy (CP) phenotypes and bronchopulmonary dysplasia (BPD) severity and, in the process, to generate hypotheses regarding causal pathways linking BPD to CP...
- Early cranial ultrasound lesions predict microcephaly at age 2 years in preterm infantsKalpathy S Krishnamoorthy
Department of Neurology Pediatrics, Massachusetts General Hospital, Boston, Massachusetts, Harvard Medical School, Harvard University, Boston, Massachusetts, USA
J Child Neurol 26:188-94. 2011..Focal white-matter lesion (echolucent lesion) and diffuse white-matter damage (ventriculomegaly) predict an increased risk of microcephaly...
- Birth weight- and fetal weight-growth restriction: impact on neurodevelopmentIris G Streimish
Newborn Medicine, Newton Wellesley Hospital, Newton, MA, USA
Early Hum Dev 88:765-71. 2012..The newborn classified as growth-restricted on fetal weight curves, but not on birth weight curves, is classified prenatally as small for gestational age (SGA), but postnatally as appropriate for gestational age (AGA)...
- Microbiologic and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy. the ELGAN studyAlan Leviton
Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatr Res 67:95-101. 2010..Organism recovery does not seem to be needed for placenta inflammation to predict diparetic CP...
- Behaviour at eight years in children with surgically corrected transposition: The Boston Circulatory Arrest TrialDavid C Bellinger
Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Cardiol Young 19:86-97. 2009..Children with congenitally malformed hearts who underwent reparative surgery in infancy using a strategy of severe haemodilution and alpha stat are at increased risk of behavioural problems in middle childhood...
- Neurodevelopment of extremely preterm infants who had necrotizing enterocolitis with or without late bacteremiaCamilia R Martin
Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard University, Boston, MA, USA
J Pediatr 157:751-6.e1. 2010..To evaluate neurodevelopment after necrotizing enterocolitis (NEC) and late bacteremia, alone and together...
- Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniquesJane E Stewart
Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
J Perinatol 22:37-45. 2002....
- Systemic hypotension and white-matter damage in preterm infantsOlaf Dammann
Children s Hospital, Boston, MA 02115, USA
Dev Med Child Neurol 44:82-90. 2002..In sum, these results do not support the hypothesis that systemic hypotension contributes to echolucency among preterm infants...
- Factors associated with microcephaly at school age in a very-low-birthweight populationClaudia A Chiriboga
Division of Pediatric Neurology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Dev Med Child Neurol 45:796-801. 2003..In multivariate analyses predicting IQ at age 7 years, microcephaly was found to modify the association between neonatal lung disease and IQ...
- Antecedents of inflammation biomarkers in preterm newborns on days 21 and 28Alan Leviton
Neuroepidemiology Unit, Department of Neurology, Boston Children s Hospital, Harvard Medical School, Boston, MA, USA
Acta Paediatr 105:274-80. 2016..The purpose of this study was to identify some of the antecedents of systemic inflammation evident during postnatal weeks three and four...
- Weight Status in the First 2 Years of Life and Neurodevelopmental Impairment in Extremely Low Gestational Age NewbornsMandy B Belfort
Department of Pediatric Newborn Medicine, Brigham and Women s Hospital, Boston, MA
J Pediatr 168:30-35.e2. 2016..To examine the extent to which weight gain and weight status in the first 2 years of life relate to the risk of neurodevelopmental impairment in extremely preterm infants...
- Association of Duchenne muscular dystrophy with autism spectrum disorderJoyce Y Wu
Division of Pediatric Neurology, David Geffen School of Medicine, Mattel Children s Hospital at UCLA, Los Angeles, CA, USA
J Child Neurol 20:790-5. 2005....
- Perinatal infection, fetal inflammatory response, white matter damage, and cognitive limitations in children born pretermOlaf Dammann
Neuroepidemiology Unit, Department of Neurology, Children s Hospital, Boston, Massachusetts 02115, USA
Ment Retard Dev Disabil Res Rev 8:46-50. 2002..We conclude that the relationship between antenatal infection and cognitive limitations deserves much further attention by researchers interested in the prevention of this undesirable outcome of prematurity...
- Brain disorders associated with corticotropin-releasing hormone expression in the placenta among children born before the 28th week of gestationAlan Leviton
Boston Children s Hospital and Harvard Medical School, Boston, MA, USA
Acta Paediatr 105:e7-e11. 2016..To evaluate the relationship between placenta corticotropin-releasing hormone (CRH) expression and brain structure and function abnormalities in extremely preterm newborns...
- Length of stay after infant heart surgery is related to cognitive outcome at age 8 yearsJane W Newburger
Department of Cardiology, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Pediatr 143:67-73. 2003..To test the hypothesis that postoperative length of stay (LOS) after infant heart surgery might be an easily measured surrogate marker for various events that culminate in later adverse cognitive outcome...