Alana T Brennan

Summary

Affiliation: Boston University
Country: USA

Publications

  1. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
  2. pmc Relationship between renal dysfunction, nephrotoxicity and death among HIV adults on tenofovir
    Alana Brennan
    Center for Global Health and Development, Boston University, Massachusetts, USA
    AIDS 25:1603-9. 2011
  3. pmc Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment
    Alana T Brennan
    Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:2027-36. 2011
  4. pmc The importance of clinic attendance in the first six months on antiretroviral treatment: a retrospective analysis at a large public sector HIV clinic in South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Int AIDS Soc 13:49. 2010
  5. doi request reprint Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
  6. pmc Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa
    Matthew P Fox
    Centre for Global Health and Development, Boston University, Boston, MA, USA
    Int J Epidemiol 42:430-9. 2013
  7. pmc Gender differences in mortality and CD4 count response among virally suppressed HIV-positive patients
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Womens Health (Larchmt) 22:113-20. 2013
  8. pmc The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:619-31. 2013
  9. pmc The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:19065. 2014
  10. pmc Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa
    Mhairi Maskew
    1Department of Medicine, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Int Assoc Physicians AIDS Care (Chic) 11:57-65. 2012

Detail Information

Publications18

  1. pmc Increases in regimen durability associated with the introduction of tenofovir at a large public-sector clinic in Johannesburg, South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Faculty of Health Sciences, Department of Internal Medicine, School of Clinical Medicine, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 16:18794. 2013
    ..We evaluated changes over time in regimen durability at the Themba Lethu Clinic, Johannesburg, South Africa...
  2. pmc Relationship between renal dysfunction, nephrotoxicity and death among HIV adults on tenofovir
    Alana Brennan
    Center for Global Health and Development, Boston University, Massachusetts, USA
    AIDS 25:1603-9. 2011
    ..We analyzed the relationship between renal dysfunction at tenofovir initiation, nephrotoxicity and mortality...
  3. pmc Outcomes of stable HIV-positive patients down-referred from a doctor-managed antiretroviral therapy clinic to a nurse-managed primary health clinic for monitoring and treatment
    Alana T Brennan
    Health Economics and Epidemiology Research Office, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    AIDS 25:2027-36. 2011
    ....
  4. pmc The importance of clinic attendance in the first six months on antiretroviral treatment: a retrospective analysis at a large public sector HIV clinic in South Africa
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Int AIDS Soc 13:49. 2010
    ..Adherence to care and treatment are essential for HIV-infected individuals to benefit from antiretroviral therapy (ART). We sought to quantify the effects on treatment outcomes of missing visits soon after initiating ART...
  5. doi request reprint Impact of choice of NRTI in first-line antiretroviral therapy: a cohort analysis of stavudine vs. tenofovir
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 19:490-8. 2014
    ..We examined treatment outcomes over 24 months amongst patients initiated on tenofovir-based vs. stavudine-based first-line regimens...
  6. pmc Cohort profile: the Themba Lethu Clinical Cohort, Johannesburg, South Africa
    Matthew P Fox
    Centre for Global Health and Development, Boston University, Boston, MA, USA
    Int J Epidemiol 42:430-9. 2013
    ..The data collected include demographics, clinical visit data, laboratory data, medication history and clinical diagnoses. Requests for collaborations on analyses can be submitted to our data centre...
  7. pmc Gender differences in mortality and CD4 count response among virally suppressed HIV-positive patients
    Mhairi Maskew
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Womens Health (Larchmt) 22:113-20. 2013
    ..We investigated the gender differences in treatment response among HIV-positive patients virally suppressed within 6 months of treatment initiation...
  8. pmc The interplay between CD4 cell count, viral load suppression and duration of antiretroviral therapy on mortality in a resource-limited setting
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA, USA Health Economics and Epidemiology Research Office, University of the Witwatersrand, Johannesburg, South Africa
    Trop Med Int Health 18:619-31. 2013
    ..To examine the interaction between CD4 cell count, viral load suppression and duration of antiretroviral therapy (ART) on mortality...
  9. pmc The relation between efavirenz versus nevirapine and virologic failure in Johannesburg, South Africa
    Kate Shearer
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:19065. 2014
    ..We investigated this hypothesis in a cohort of HIV-positive patients at a large HIV treatment clinic in South Africa...
  10. pmc Poorer ART outcomes with increasing age at a large public sector HIV clinic in Johannesburg, South Africa
    Mhairi Maskew
    1Department of Medicine, Clinical HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    J Int Assoc Physicians AIDS Care (Chic) 11:57-65. 2012
    ..As the current HIV-positive population ages, the absolute number of patients >50 years on treatment is increasing...
  11. doi request reprint Tenofovir stock shortages have limited impact on clinic- and patient-level HIV treatment outcomes in public sector clinics in South Africa
    Alana T Brennan
    Department of Global Health, Boston University School of Public Health, Boston, MA, USA
    Trop Med Int Health . 2016
    ..Using data from four public sector clinics in South Africa, we sought to investigate provider- and patient-level outcomes, to understand how the 2012 tenofovir stock shortage affected the HIV care and monitoring of ART patients...
  12. pmc Poor CD4 recovery and risk of subsequent progression to AIDS or death despite viral suppression in a South African cohort
    Simbarashe Takuva
    Clinical HIV Research Unit, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    J Int AIDS Soc 17:18651. 2014
    ..The prognostic role of CD4 response in the first six months of treatment in patients achieving early viral suppression during HIV treatment is unclear...
  13. pmc Rates and cost of hospitalization before and after initiation of antiretroviral therapy in urban and rural settings in South Africa
    Gesine Meyer-Rath
    Center for Global Health and Development, Boston University, Boston, MA, USA
    J Acquir Immune Defic Syndr 62:322-328. 2013
    ..Raising ART eligibility thresholds could avoid the high cost of hospitalization before and immediately after ART initiation...
  14. pmc Treatment outcomes of HIV-positive patients on first-line antiretroviral therapy in private versus public HIV clinics in Johannesburg, South Africa
    Faith Moyo
    Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
    Clin Epidemiol 8:37-47. 2016
    ..While many studies have investigated patient-level causes of poor treatment outcomes, data on the effect of health systems on ART outcomes are scarce...
  15. doi request reprint A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children
    Alana T Brennan
    aDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA bHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Epidemiology, Boston University School of Public Health dDepartment of Pediatrics, Boston University School of Medicine, Boston, Massachusetts, USA
    AIDS 30:2351-60. 2016
    ..Conduct a meta-analysis examining differential all-cause mortality rates between HIV-exposed uninfected (HEU) infants and children as compared with their HIV-unexposed uninfected (HUU) counterparts...
  16. doi request reprint Mortality in the First 3 Months on Antiretroviral Therapy Among HIV-Positive Adults in Low- and Middle-income Countries: A Meta-analysis
    Alana T Brennan
    Center for Global Health and Development, Boston University, Boston, MA Health Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa andDepartments of Epidemiology Global Health, Boston University School of Public Health, Boston, MA
    J Acquir Immune Defic Syndr 73:1-10. 2016
    ..Continued financial investments by multinational partners and the implementation of creative interventions to mitigate multidimensional complex barriers of accessing care and treatment for HIV are needed. ..
  17. ncbi request reprint Has the phasing out of stavudine in accordance with changes in WHO guidelines led to a decrease in single-drug substitutions in first-line antiretroviral therapy for HIV in sub-Saharan Africa?
    Alana T Brennan
    aDepartment of Global Health, Boston University, Boston, Massachusetts, USA bHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cDepartment of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA dCentre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa eDepartment of Infectious Diseases, Bern University Hospital, University of Bern fInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland gThe Desmond Tutu HIV Centre, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town hDivision of Infectious Diseases, Department of Medicine, University of Stellenbosch and Tygerberg Academic Hospital, Cape Town iAfrica Center for Health and Population Studies, University of Kwazulu Natal jKheth Impilo AIDS Free Living, Cape Town kDepartment of Health, Provincial Government of the Western Cape, Cape Town, South Africa lCenter for Infectious Disease Research in Zambia, Lusaka, Zambia mIndiana University School of Medicine, Indianapolis nRichard M Fairbanks School of Public Health, Indiana University, Indianapolis, Indiana, USA oINSERM U1027,
    AIDS 31:147-157. 2017
    ....
  18. pmc Effect of antiretroviral therapy on patients' economic well being: five-year follow-up
    Sydney Rosen
    aCenter for Global Health and Development, Boston University, Boston, Massachusetts, USA bHealth Economics and Epidemiology Research Office, Department of Internal Medicine, School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cBrown University, School of Public Health, Providence, Rhode Island, USA
    AIDS 28:417-24. 2014
    ..Evaluate the effect of antiretroviral therapy (ART) on South African HIV patients' economic well being, as indicated by symptoms, normal activities, employment, and external support, during the first 5 years on treatment...