Ronald J Pettis

Summary

Affiliation: BD Biosciences
Country: USA

Publications

  1. ncbi request reprint Microneedle delivery: clinical studies and emerging medical applications
    Ronald J Pettis
    BD Technologies, P O Box 12016, 21 Davis Drive, Research Triangle Park, NC 27709, USA
    Ther Deliv 3:357-71. 2012
  2. doi request reprint Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:443-50. 2011
  3. pmc Pharmacokinetics and postprandial glycemic excursions following insulin lispro delivered by intradermal microneedle or subcutaneous infusion
    Elaine McVey
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    J Diabetes Sci Technol 6:743-54. 2012
  4. doi request reprint Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs
    Alfred J Harvey
    BD Technologies, 21 Davis Drive, Research Triangle Park, North Carolina 27709, USA
    Pharm Res 28:107-16. 2011
  5. pmc Intradermal insulin infusion achieves faster insulin action than subcutaneous infusion for 3-day wear
    Christopher James Rini
    BD Technologies, Durham, NC, USA
    Drug Deliv Transl Res 5:332-45. 2015
  6. doi request reprint Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:435-42. 2011
  7. pmc Evaluation of Intradermal and Subcutaneous Infusion Set Performance Under 24-Hour Basal and Bolus Conditions
    Elaine McVey
    BD Technologies, Research Triangle Park, NC, USA MaxPoint Interactive, Morrisville, NC, USA
    J Diabetes Sci Technol 9:1282-91. 2015
  8. pmc Intrinsic fibrillation of fast-acting insulin analogs
    R Jeremy Woods
    BD Technologies, Durham, North Carolina 27709, USA
    J Diabetes Sci Technol 6:265-76. 2012
  9. pmc Characterizing normal-use temperature conditions of pumped insulin
    Joshua K Herr
    Becton Dickinson Technologies, Research Triangle Park, NC, USA
    J Diabetes Sci Technol 8:850-4. 2014
  10. ncbi request reprint Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    John A Mikszta
    BD Technologies, Research Triangle Park, North Carolina, USA
    Nat Med 8:415-9. 2002

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Microneedle delivery: clinical studies and emerging medical applications
    Ronald J Pettis
    BD Technologies, P O Box 12016, 21 Davis Drive, Research Triangle Park, NC 27709, USA
    Ther Deliv 3:357-71. 2012
    ..This review summarizes the various aspects of microneedle clinical evaluation to date and identifies areas requiring further clinical evaluation...
  2. doi request reprint Microneedle-based intradermal versus subcutaneous administration of regular human insulin or insulin lispro: pharmacokinetics and postprandial glycemic excursions in patients with type 1 diabetes
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:443-50. 2011
    ....
  3. pmc Pharmacokinetics and postprandial glycemic excursions following insulin lispro delivered by intradermal microneedle or subcutaneous infusion
    Elaine McVey
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    J Diabetes Sci Technol 6:743-54. 2012
    ..We compared the PK and pharmacodynamic (PD) effects of insulin lispro administered before two daily standardized solid mixed meals (breakfast and lunch), using microneedle-based ID or traditional subcutaneous (SC) delivery...
  4. doi request reprint Microneedle-based intradermal delivery enables rapid lymphatic uptake and distribution of protein drugs
    Alfred J Harvey
    BD Technologies, 21 Davis Drive, Research Triangle Park, North Carolina 27709, USA
    Pharm Res 28:107-16. 2011
    ..The purpose of this research was to examine the pharmacokinetics (PK) of drug uptake for microneedle-based intradermal (ID) delivery of several classes of protein drugs compared to standard subcutaneous (SC) administration...
  5. pmc Intradermal insulin infusion achieves faster insulin action than subcutaneous infusion for 3-day wear
    Christopher James Rini
    BD Technologies, Durham, NC, USA
    Drug Deliv Transl Res 5:332-45. 2015
    ..5 or 0-2 h time period. Intradermal delivery of insulin is a viable delivery route alternative providing reduced time for insulin absorption with less intra-subject variability and lower glycemic response. ..
  6. doi request reprint Intradermal microneedle delivery of insulin lispro achieves faster insulin absorption and insulin action than subcutaneous injection
    Ronald J Pettis
    BD Technologies, Research Triangle Park, North Carolina 27709, USA
    Diabetes Technol Ther 13:435-42. 2011
    ..This study compared insulin lispro (IL) pharmacokinetics (PK) and pharmacodynamics (PD) delivered via microneedle intradermal (ID) injection with subcutaneous (SC) injection under euglycemic glucose clamp conditions...
  7. pmc Evaluation of Intradermal and Subcutaneous Infusion Set Performance Under 24-Hour Basal and Bolus Conditions
    Elaine McVey
    BD Technologies, Research Triangle Park, NC, USA MaxPoint Interactive, Morrisville, NC, USA
    J Diabetes Sci Technol 9:1282-91. 2015
    ..This study sought to assess the function and delivery reliability of intradermal (ID) infusion sets used with commercial insulin pumps...
  8. pmc Intrinsic fibrillation of fast-acting insulin analogs
    R Jeremy Woods
    BD Technologies, Durham, North Carolina 27709, USA
    J Diabetes Sci Technol 6:265-76. 2012
    ....
  9. pmc Characterizing normal-use temperature conditions of pumped insulin
    Joshua K Herr
    Becton Dickinson Technologies, Research Triangle Park, NC, USA
    J Diabetes Sci Technol 8:850-4. 2014
    ..Results from this study could be utilized to develop more accurate stability and compatibility testing procedures for new insulin formulations and/or delivery devices. ..
  10. ncbi request reprint Improved genetic immunization via micromechanical disruption of skin-barrier function and targeted epidermal delivery
    John A Mikszta
    BD Technologies, Research Triangle Park, North Carolina, USA
    Nat Med 8:415-9. 2002
    ..Together, the results provide the first in vivo use of microfabricated devices to breach the skin barrier and deliver vaccines topically, suggesting significant clinical and practical advantages over existing technologies...