Pascal O Zinn
Affiliation: Baylor College of Medicine
- Imaging genomic mapping of an invasive MRI phenotype predicts patient outcome and metabolic dysfunction: a TCGA glioma phenotype research group projectRivka R Colen
Department of Diagnostic Radiology, M, d, Anderson Cancer Center, 1400 Pressler St Unit 1482, Rm FCT 16, 5037, Houston, TX 77030, USA
BMC Med Genomics 7:30. 2014..We thus seek to identify those genomic abnormalities associated with a highly aggressive and invasive GBM imaging-phenotype...
- Extent of resection and radiotherapy in GBM: A 1973 to 2007 surveillance, epidemiology and end results analysis of 21,783 patientsPascal O Zinn
Department of Neurosurgery, Baylor College of Medicine, Houston, TX, USA
Int J Oncol 42:929-34. 2013..However, across all age groups multimodality treatment with surgery and RT continues to provide the largest survival benefit compared to either treatment alone and, thus, should be pursued whenever feasible...
- A novel volume-age-KPS (VAK) glioblastoma classification identifies a prognostic cognate microRNA-gene signaturePascal O Zinn
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, United States of America
PLoS ONE 7:e41522. 2012..Thus, we present for the first time a biologically relevant, and clinically applicable tumor Volume, patient Age, and KPS (VAK) GBM classification that can easily and non-invasively be determined upon patient admission...
- Radiogenomic mapping of edema/cellular invasion MRI-phenotypes in glioblastoma multiformePascal O Zinn
Department of Genetics, MD Anderson Cancer Center, University of Texas, Houston, Texas, United States of America
PLoS ONE 6:e25451. 2011..Here, we present the first comprehensive radiogenomic analysis using quantitative MRI volumetrics and large-scale gene- and microRNA expression profiling in GBM...
- REST regulates oncogenic properties of glioblastoma stem cellsMohamed M Kamal
Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
Stem Cells 30:405-14. 2012..Thus, based on our results, we propose that a novel function of REST is to maintain self-renewal and other oncogenic properties of GSCs and that REST can play a major role in mediating tumorigenicity in GBM...
- Imaging Genomics in GliomasPascal O Zinn
From the Department of Diagnostic Radiology, University of Texas, MD Anderson Cancer Center and Department of Neurosurgery, Baylor College of Medicine, Houston, TX
Cancer J 21:225-34. 2015..This article reviews the fundamentals of imaging genomics in glioma, its role in noninvasive genomic detection, and its future potential in personalized treatment planning. ..
- Glioblastoma: imaging genomic mapping reveals sex-specific oncogenic associations of cell deathRivka R Colen
From the Department of Radiology, University of Texas MD Anderson Cancer Center, 1400 Pressler St, Unit 1482, Houston, TX 77030 R R C, J W, S K S, P O Z Department of Biomedical Informatics, Emory University, Atlanta, Ga D A G and Department of Neurosurgery, Baylor College of Medicine, Houston, Tex P O Z
Radiology 275:215-27. 2015..To identify the molecular profiles of cell death as defined by necrosis volumes at magnetic resonance (MR) imaging and uncover sex-specific molecular signatures potentially driving oncogenesis and cell death in glioblastoma (GBM)...
- Imaging Genomics of Glioblastoma: Biology, Biomarkers, and BreakthroughsSafwan Moton
From the Department of Diagnostic and Radiology, University of Texas, MD Anderson Cancer Center Department of Neurosurgery and Baylor College of Medicine and Department of Cancer Systems Imaging, University of Texas, MD Anderson Cancer Center, Houston, TX
Top Magn Reson Imaging 24:155-63. 2015....
- Imaging genomics of Glioblastoma: state of the art bridge between genomics and neuroradiologyMohamed G ElBanan
Department of Diagnostic Radiology, MD Anderson Cancer Center, University of Texas, 1400 Pressler Street, Houston, TX 77030, USA
Neuroimaging Clin N Am 25:141-53. 2015..This article discusses the basics of imaging genomics of GBM, its role in treatment decision-making, and its future potential in noninvasive genomic identification. ..
- Posterior leukoencephalopathy following repair of an ileocecal anastomosis breakdown: a case report and review of the literaturePascal O Zinn
Department of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA 02115, USA
J Med Case Reports 5:20. 2011..abstract:..