Christine Beeton

Summary

Affiliation: Baylor College of Medicine
Country: USA

Publications

  1. pmc Erratum to: Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes.
    Zolt n Peth
    Arthritis Res Ther 18:122. 2016
  2. pmc Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
  3. pmc Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases
    Christine Beeton
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Inflamm Allergy Drug Targets 10:313-21. 2011
  4. pmc KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis
    Mark R Tanner
    Baylor College of Medicine, Houston, Texas
    Arthritis Rheumatol 67:96-106. 2015
  5. pmc Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes
    Zoltán Pethő
    Department of Molecular Physiology and Biophysics, Mail Stop BCM335, Room S409A, Baylor College of Medicine, Houston, TX, 77030, USA
    Arthritis Res Ther 18:103. 2016
  6. pmc Functional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblasts
    Rajeev B Tajhya
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Death Dis 7:e2426. 2016
  7. pmc Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation
    Redwan Huq
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Sci Rep 6:33808. 2016
  8. pmc Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes
    Shyny Koshy
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 8:e76740. 2013
  9. pmc KCa1.1 potassium channels regulate key proinflammatory and invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis
    Xueyou Hu
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 287:4014-22. 2012
  10. pmc Characterization of a novel MR-detectable nanoantioxidant that mitigates the recall immune response
    Taeko Inoue
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
    NMR Biomed 29:1436-44. 2016

Collaborators

  • Frank T Horrigan
  • Gyorgy Panyi
  • Heike Wulff
  • Percio S Gulko
  • Raymond S Norton
  • Redwan Huq
  • Rajeev B Tajhya
  • Mark R Tanner
  • Xueyou Hu
  • Teresina Laragione
  • Taeko Inoue
  • Fatima S Khan
  • Shyny Koshy
  • Errol L G Samuel
  • Zoltán Pethő
  • James M Tour
  • Zolt n Peth
  • Robia G Pautler
  • George G Rodney
  • B Vijayalakshmi Ayyar
  • Chang Seok Lee
  • Iskander I Ismailov
  • Liang Sun
  • Patricia Yotnda
  • Gary Stinnett
  • Joel R Neilson
  • William K A Sikkema
  • Natee Kongchan
  • Rutvik S Patel
  • Paul C Porter
  • David B Corry
  • Lizanne G Nilewski
  • Simone H Ruano
  • Lubov T Timchenko
  • Deric M Griffin
  • Tabassum J Majid
  • Thomas Lee
  • Johanna Lanner
  • M Zouhair Atassi
  • Keke Dong
  • Amy Hanna
  • Cheng Long
  • Alla Lyfenko
  • Ted Tran
  • Dimitra K Georgiou
  • Viktor Yarotskyy
  • Pumin Zhang
  • Mary E Dickinson
  • Susan L Hamilton
  • Robert T Dirksen
  • Mark Knoblauch
  • Michael W Swank
  • Ross A Poche
  • Adan Dagnino-Acosta
  • Michael W Pennington
  • DanLi Wu
  • Karlie R Jones

Detail Information

Publications13

  1. pmc Erratum to: Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes.
    Zolt n Peth
    Arthritis Res Ther 18:122. 2016
  2. pmc Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function
    Chang Seok Lee
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030 USA
    Skelet Muscle 5:4. 2015
    ..1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through CaV1.1 during sustained muscle activity plays a functional role in mammalian skeletal muscle has not been assessed...
  3. pmc Analogs of the sea anemone potassium channel blocker ShK for the treatment of autoimmune diseases
    Christine Beeton
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Inflamm Allergy Drug Targets 10:313-21. 2011
    ..They are currently undergoing further evaluation as potential immunomodulators for the treatment of autoimmune diseases...
  4. pmc KCa1.1 inhibition attenuates fibroblast-like synoviocyte invasiveness and ameliorates disease in rat models of rheumatoid arthritis
    Mark R Tanner
    Baylor College of Medicine, Houston, Texas
    Arthritis Rheumatol 67:96-106. 2015
    ..The purpose of this study was to define the importance of KCa1.1 (BK, Maxi-K, Slo1, KCNMA1) channel expression and function in FLS and to establish these channels as potential new targets for RA therapy...
  5. pmc Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes
    Zoltán Pethő
    Department of Molecular Physiology and Biophysics, Mail Stop BCM335, Room S409A, Baylor College of Medicine, Houston, TX, 77030, USA
    Arthritis Res Ther 18:103. 2016
    ..Identification of the regulatory subunits of KCa1.1 expressed by RA-FLS may therefore provide the opportunity for generating a selective target for RA treatment...
  6. pmc Functional KCa1.1 channels are crucial for regulating the proliferation, migration and differentiation of human primary skeletal myoblasts
    Rajeev B Tajhya
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USA
    Cell Death Dis 7:e2426. 2016
    ..Our results identify KCa1.1 channels as crucial regulators of skeletal myogenesis and suggest these channels as novel therapeutic targets in DM1...
  7. pmc Preferential uptake of antioxidant carbon nanoparticles by T lymphocytes for immunomodulation
    Redwan Huq
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    Sci Rep 6:33808. 2016
    ..Our results suggest the preferential targeting of PEG-HCCs to T lymphocytes as a novel approach for T lymphocyte immunomodulation in autoimmune diseases without affecting other immune cells...
  8. pmc Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes
    Shyny Koshy
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, United States of America
    PLoS ONE 8:e76740. 2013
    ..This results in a TRAM-34-induced increased ability of A-NK cells to reduce in vivo tumor growth. Taken together, our results suggest that targeting KCa3.1 on NK cells with selective blockers may be beneficial in cancer immunotherapy. ..
  9. pmc KCa1.1 potassium channels regulate key proinflammatory and invasive properties of fibroblast-like synoviocytes in rheumatoid arthritis
    Xueyou Hu
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas 77030, USA
    J Biol Chem 287:4014-22. 2012
    ..Our findings indicate a regulatory role of KCa1.1 channels in RA-FLS function and suggest this channel as a potential target for the treatment of RA...
  10. pmc Characterization of a novel MR-detectable nanoantioxidant that mitigates the recall immune response
    Taeko Inoue
    Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, USA
    NMR Biomed 29:1436-44. 2016
    ..PEG-HCCs can be modified to allow for both in vitro and in vivo visualization using MRI. © 2016 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd. ..
  11. pmc Antigenic sites on the HN domain of botulinum neurotoxin A stimulate protective antibody responses against active toxin
    B Vijayalakshmi Ayyar
    Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
    Sci Rep 5:15776. 2015
    ..These results are the first to describe and dissect the protective activity of the BoNT/A HN domain. ..