Affiliation: Barrow Neurological Institute
- Centrally administered pertussis toxin inhibits microglia migration to the spinal cord and prevents dissemination of disease in an EAE mouse modelJun xiang Yin
Department of Neurology, Barrow Neurological Institute, Phoenix, Arizona, United States of America
PLoS ONE 5:e12400. 2010..This study was designed to investigate the effects of PTx administered intracerebroventricularly (icv) in preventing downstream immune cell infiltration and demyelination of the spinal cord...
- APOE ε4 is associated with exacerbation of cognitive decline in patients with multiple sclerosisJiong Shi
Division of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ, USA
Cogn Behav Neurol 24:128-33. 2011..In this follow-up study, we have assessed whether APOE ε4 status exacerbates progression of cognitive deficits in MS...
- APOE epsilon 4 allele is associated with cognitive impairment in patients with multiple sclerosisJ Shi
Division of Neurology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
Neurology 70:185-90. 2008..Its role in multiple sclerosis (MS) is less clear, though studies indicate that 40% to 60% of patients with MS have evidence of cognitive impairment...
- A new EAE model of brain demyelination induced by intracerebroventricular pertussis toxinC B Zhao
Department of Neurology, Barrow Neurological Institute, 500 W Thomas Road, Suite 720, Phoenix, AZ 85013, USA
Biochem Biophys Res Commun 370:16-21. 2008..We thus generated a highly reproducible model with remarkable histological similarities to the predominant demyelinating brain lesions seen in MS...
- Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's diseaseR P Friedland
Department of Neurology, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA
Ann N Y Acad Sci 903:123-8. 2000..These findings suggest that the transgenic mouse may be used as a model for evaluation of A beta imaging methods...
- Senescent ventricular dysfunction: issues related to cardiopulmonary bypassD F Larson
Circulatory Sciences Graduate Perfusion Program, Sarver Heart Center, Tucson, Arizona, USA
J Extra Corpor Technol 32:142-7. 2000....
- Association between apolipoprotein CI HpaI polymorphism and sporadic Alzheimer's disease in ChineseJ Shi
Department of Medical Genetics, West China Hospital, Sichuan University, Chengdu, China
Acta Neurol Scand 109:140-5. 2004..To investigate into the relationship of apolipoprotein CI (ApoCI) polymorphism with sporadic Alzheimer's disease (AD) in Chinese...
- A polymorphism in the angiotensin 1-converting enzyme gene is associated with damage to cerebral cortical white matter in Alzheimer's diseaseJ Tian
Clinical Neuroscience Research Group, Department of Medicine, University of Manchester, Manchester, M13 9PT, UK
Neurosci Lett 354:103-6. 2004....
- Cyclooxygenase-2 gene polymorphisms in an Australian population: association of the -1195G > A promoter polymorphism with mild asthmaJ Shi
Lung Institute of Western Australia and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, WA, Australia
Clin Exp Allergy 38:913-20. 2008..Single nucleotide polymorphisms (SNPs) of the COX-2 gene may influence gene transcription and PG production in the asthmatic airway...
- Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's diseaseA M Shiarli
Clinical Neuroscience Research Group, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Salford, UK
Neuropathol Appl Neurobiol 32:374-87. 2006....
- Genetic associations between cathepsin D exon 2 C-->T polymorphism and Alzheimer's disease, and pathological correlations with genotypeY Davidson
Clinical Neuroscience Research Group, University of Manchester, Greater Manchester Neurosciences Centre, Hope Hospital, Stott Lane, Salford M6 8HD, Manchester, UK
J Neurol Neurosurg Psychiatry 77:515-7. 2006....
- Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopyJ Shi
Cooperative Research Centre for Asthma, Australia
Eur Respir J 26:249-56. 2005..22TT genotype confers a small protective effect against atopy. Potential associations with aspirin-intolerant asthma were identified and warrant further investigation in a larger population of aspirin-intolerant asthma patients...
- A functional polymorphism in the promoter region of the cyclooxygenase-2 gene is not associated with asthma and atopy in an Australian populationJ Shi
Asthma and Allergy Research Institute Inc and Centre for Asthma, Allergy and Respiratory Research, The University of Western Australia, Perth, Australia
Clin Exp Allergy 34:1714-8. 2004..We hypothesized that this polymorphism, which may result in decreased COX-2 transcription, could be associated with more severe asthma, and/or aspirin-intolerant asthma (AIA)...
- Association between apolipoprotein E e4 allele and arteriosclerosis, cerebral amyloid angiopathy, and cerebral white matter damage in Alzheimer's diseaseJ Tian
Clinical Neuroscience Research Group, University of Manchester, Hope Hospital, Salford, Manchester M6 8HD, UK
J Neurol Neurosurg Psychiatry 75:696-9. 2004....
- Isolation, characterization, and chromosomal location of the mouse enamelysin geneJ Caterina
National Institute of Dental and Craniofacial Research, Bethesda, Maryland 20892, USA
Genomics 62:308-11. 1999..It is expressed exclusively in ameloblasts and odontoblasts. The mouse enamelysin gene (Mmp20) is made up of 10 exons spanning approximately 65 kb within the MMP gene cluster at the centromeric end of chromosome 9...
- Cloning and characterization of nnrR, whose product is required for the expression of proteins involved in nitric oxide metabolism in Rhodobacter sphaeroides 2.4.3I E Tosques
Department of Microbiology, Cornell University, Ithaca, New York 14853, USA
J Bacteriol 178:4958-64. 1996..sphaeroides 2.4.1. The likely effector of NnrR activity, as determined on the basis of work detailed in this paper and other studies, is discussed...