A A Skripchenko

Summary

Affiliation: American Red Cross
Country: USA

Publications

  1. doi request reprint Maintenance of storage properties of pediatric aliquots of apheresis platelets in fluoroethylene propylene containers
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Rockville, Maryland 20855, USA
    Transfusion 53:872-7. 2013
  2. doi request reprint A rest period before agitation may improve some in vitro apheresis platelet parameters during storage
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Rockville, MD, USA
    Transfusion 52:1433-8. 2012
  3. doi request reprint Mitochondrial dysfunction of platelets stored in first- and second-generation containers is, in part, associated with elevated carbon dioxide levels
    Andrey Skripchenko
    American Red Cross Biomedical Services and Holland Laboratory, Rockville, Maryland, USA
    Transfusion 51:371-9. 2011
  4. doi request reprint Periods without agitation diminish platelet mitochondrial function during storage
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 50:390-9. 2010
  5. doi request reprint Platelet products prepared by different methods of sedimentation undergo platelet activation differently during storage
    Andrey Skripchenko
    The American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 48:1469-77. 2008
  6. ncbi request reprint Inactivation of WBCs in RBC suspensions by photoactive phenothiazine dyes: comparison of dimethylmethylene blue and MB
    A A Skripchenko
    Product Development Department, Jerome Holland Laboratory, American Red Cross, Rockville, Maryland 20855 2734, USA
    Transfusion 40:968-75. 2000
  7. ncbi request reprint In vivo recovery and survival of red cells after photodynamic treatment with thiopyrylium and red light using a canine model
    A Skripchenko
    Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Vox Sang 92:157-9. 2007
  8. ncbi request reprint Thiazole orange, a DNA-binding photosensitizer with flexible structure, can inactivate pathogens in red blood cell suspensions while maintaining red cell storage properties
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 46:213-9. 2006
  9. ncbi request reprint Chalcogenoxanthylium photosensitizers for the photodynamic purging of blood-borne viral and bacterial pathogens
    Stephen J Wagner
    American Red Cross, Holland Laboratory for the Biomedical Sciences, Rockville, MD 20855, USA
    Bioorg Med Chem 13:5927-35. 2005
  10. ncbi request reprint Use of a red cell band 3-ligand/antioxidant to improve red cell storage properties following virucidal phototeatment with chalcogenoxanthylium photosensitizers
    Stephen J Wagner
    Blood Components Department, American Red Cross Holland Laboratory for the Biomedical Sciences, Rockville, MD, USA
    Photochem Photobiol 82:1595-600. 2006

Detail Information

Publications24

  1. doi request reprint Maintenance of storage properties of pediatric aliquots of apheresis platelets in fluoroethylene propylene containers
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Rockville, Maryland 20855, USA
    Transfusion 53:872-7. 2013
    ..Gas-permeable fluoroethylene propylene (FEP) containers have been used in the storage of cell therapy preparations and are available in multiple sizes as single containers but have not been evaluated for PLT storage...
  2. doi request reprint A rest period before agitation may improve some in vitro apheresis platelet parameters during storage
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Rockville, MD, USA
    Transfusion 52:1433-8. 2012
    ..It is possible that a rest period may help to disperse PLT aggregates. It is not established whether apheresis PLTs require a rest period before agitation and what the length of this period should be...
  3. doi request reprint Mitochondrial dysfunction of platelets stored in first- and second-generation containers is, in part, associated with elevated carbon dioxide levels
    Andrey Skripchenko
    American Red Cross Biomedical Services and Holland Laboratory, Rockville, Maryland, USA
    Transfusion 51:371-9. 2011
    ..The aim of this study was to evaluate mitochondrial function of PLTs stored in first- and second-generation bags with different gas permeabilities...
  4. doi request reprint Periods without agitation diminish platelet mitochondrial function during storage
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 50:390-9. 2010
    ..The aim of this study was to evaluate the influence of periods without agitation on PLT mitochondrial function, blood gases, and activation...
  5. doi request reprint Platelet products prepared by different methods of sedimentation undergo platelet activation differently during storage
    Andrey Skripchenko
    The American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 48:1469-77. 2008
    ....
  6. ncbi request reprint Inactivation of WBCs in RBC suspensions by photoactive phenothiazine dyes: comparison of dimethylmethylene blue and MB
    A A Skripchenko
    Product Development Department, Jerome Holland Laboratory, American Red Cross, Rockville, Maryland 20855 2734, USA
    Transfusion 40:968-75. 2000
    ..The present study compares WBC photoinactivation in buffy coat after DMMB or MB phototreatment under virucidal conditions...
  7. ncbi request reprint In vivo recovery and survival of red cells after photodynamic treatment with thiopyrylium and red light using a canine model
    A Skripchenko
    Holland Laboratory for the Biomedical Sciences, American Red Cross, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Vox Sang 92:157-9. 2007
    ..255 +/- 63 h, respectively). Results suggest that thiopyrylium phototreatment does not negatively affect canine RBC in vivo recovery...
  8. ncbi request reprint Thiazole orange, a DNA-binding photosensitizer with flexible structure, can inactivate pathogens in red blood cell suspensions while maintaining red cell storage properties
    Andrey Skripchenko
    American Red Cross Biomedical Services, Holland Laboratory, Blood Components Development, Rockville, Maryland 20855, USA
    Transfusion 46:213-9. 2006
    ....
  9. ncbi request reprint Chalcogenoxanthylium photosensitizers for the photodynamic purging of blood-borne viral and bacterial pathogens
    Stephen J Wagner
    American Red Cross, Holland Laboratory for the Biomedical Sciences, Rockville, MD 20855, USA
    Bioorg Med Chem 13:5927-35. 2005
    ..Photocleavage experiments with plasmid DNA and the chalcogenoxanthylium dyes suggested the genomic material contained in the virus and in the bacteria as one possible target for the photodynamic action of some of these dyes...
  10. ncbi request reprint Use of a red cell band 3-ligand/antioxidant to improve red cell storage properties following virucidal phototeatment with chalcogenoxanthylium photosensitizers
    Stephen J Wagner
    Blood Components Department, American Red Cross Holland Laboratory for the Biomedical Sciences, Rockville, MD, USA
    Photochem Photobiol 82:1595-600. 2006
    ....
  11. ncbi request reprint Use of a flow-cell system to investigate virucidal dimethylmethylene blue phototreatment in two RBC additive solutions
    Stephen Wagner
    Jerome H Holland Laboratory for the Biomedical Sciences, American Red Cross Biomedical Services, Rockville, Maryland 20855, USA
    Transfusion 42:1200-5. 2002
    ..A flow-cell system was developed to rapidly treat larger volumes of oxygenated 45 percent Hct RBCs with high-intensity red light...
  12. ncbi request reprint Quinacrine enhances vesicular stomatitis virus inactivation and diminishes hemolysis of dimethylmethylene blue-phototreated red cells
    Stephen J Wagner
    American Red Cross Biomedical Services, Jerome H Holland Laboratory for the Biomedical Sciences, Blood and Cell Therapy Development, Rockville, MD 20855, USA
    Photochem Photobiol 76:514-7. 2002
    ..These results collectively suggest that despite its recognized affinity for viral nucleic acid, DMMB also binds to RBC membranes and that the bound dye is, in part, responsible for photoinduced hemolysis...
  13. doi request reprint Influence of apheresis container size on the maintenance of platelet in vitro storage properties after a 30-h interruption of agitation
    Stephen J Wagner
    Blood Components Department, American Red Cross, Holland Laboratory, Rockville, MD 20855, USA
    Transfus Apher Sci 43:9-15. 2010
    ..17+/-06 and 0.37+/-0.09 pH units greater, n=4, respectively). Other measures showed either small differences or comparability of platelet in vitro parameters with storage in the two containers after an interruption of agitation...
  14. ncbi request reprint Calcium is a key constituent for maintaining the in vitro properties of platelets suspended in the bicarbonate-containing additive solution M-sol with low plasma levels
    Stephen J Wagner
    American Red Cross, Holland Laboratory, Rockville, Maryland 20855, USA
    Transfusion 50:1028-35. 2010
    ..PLTs suspended in M-sol, a bicarbonate-based experimental platelet additive solution (PAS), maintain in vitro PLT properties during storage with low levels of plasma (< or =5%)...
  15. ncbi request reprint Evaluation of the sensitivity of red blood cell markers to detect photodynamic membrane damage
    Stephen J Wagner
    Blood and Cell Therapy Development, American Red Cross, Biomedical Research and Development, Rockville, Maryland 20855, USA
    Transfusion 44:716-21. 2004
    ..This study compares the relative sensitivity of three assays for detecting RBC membrane damage...
  16. doi request reprint Evaluation of in vitro storage properties of prestorage pooled whole blood-derived platelets suspended in 100 percent plasma and treated with amotosalen and long-wavelength ultraviolet light
    Stephen J Wagner
    American Red Cross Biomedical Services, 15601 Crabbs Branch Way, Rockville, MD 20855, USA
    Transfusion 49:704-10. 2009
    ..This study investigated the in vitro PLT properties of amotosalen-PCT of leukoreduced pools of PLTs prepared by the PRP method and suspended in 100 percent plasma...
  17. ncbi request reprint Comparison of the in vitro properties of apheresis platelets during 7-day storage after interrupting agitation for one or three periods
    Stephen J Wagner
    Blood Components Department, American Red Cross, Holland Laboratory, Rockville, Maryland, USA
    Transfusion 48:2492-500. 2008
    ..We have previously conducted studies investigating maintenance of apheresis PLT in vitro quality measures during a single 24- or 30-hour interruption of agitation, but data are not available for multiple periods without agitation...
  18. ncbi request reprint Maintenance of platelet in vitro properties during 7-day storage in M-sol with a 30-hour interruption of agitation
    Stephen J Wagner
    Blood Components Department, American Red Cross, Holland Laboratory, Rockville, Maryland, USA
    Transfusion 48:2501-607. 2008
    ..A newly described bicarbonate-containing AS, M-sol, was compared to plasma for preservation of whole blood-derived PLT concentrates in which a 30-hour interruption of agitation was included...
  19. ncbi request reprint Use of a flexible thiopyrylium photosensitizer and competitive inhibitor for pathogen reduction of viruses and bacteria with retention of red cell storage properties
    Stephen J Wagner
    American Red Cross Biomedical Services, Holland Laboratory, Blood and Cell Therapy Development, Rockville, Maryland, USA
    Transfusion 45:752-60. 2005
    ....
  20. doi request reprint Inactivation of Leishmania donovani infantum and Trypanosoma cruzi in red cell suspensions with thiazole orange
    Stephen J Wagner
    American Red Cross, Holland Laboratory for the Biomedical Sciences, Blood Components Department, Rockville, Maryland 20855, USA
    Transfusion 48:1363-7. 2008
    ..The aim of this study is to further evaluate the ability of TO to inactivate pathogens by measuring its activity against the protozoa Leishmania donovani infantum and Trypanosoma cruzi...
  21. pmc Photoinactivation of Trypanosoma cruzi in red cell suspensions with thiopyrylium
    Stephen J Wagner
    American Red Cross Holland Laboratory, Rockville, MD 20855, USA
    Transfus Apher Sci 37:23-5. 2007
    ....
  22. ncbi request reprint The influence of simulated shipping conditions (24- or 30-hr interruption of agitation) on the in vitro properties of apheresis platelets during 7-day storage
    Stephen J Wagner
    Blood Components Department, American Red Cross, Holland Laboratory, Rockville, MD 20855, USA
    Transfusion 48:1072-80. 2008
    ..Studies have demonstrated maintenance of PLT quality of whole blood-derived PLT concentrates during a 24-hour interruption of agitation, but data are not available for apheresis PLTs in 100 percent plasma...
  23. ncbi request reprint "Switched-on" flexible chalcogenopyrylium photosensitizers. Changes in photophysical properties upon binding to DNA
    Tymish Y Ohulchanskyy
    Institute for Lasers, Photonics, and Biophotonics, Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, New York 14260, USA
    J Phys Chem B 111:9686-92. 2007
    ....
  24. ncbi request reprint Synthesis of analogues of a flexible thiopyrylium photosensitizer for purging blood-borne pathogens and binding mode and affinity studies of their complexes with DNA
    Ruel E McKnight
    Department of Chemistry, State University of New York at Geneseo, 1 College Circle, Geneseo, NY 14454, USA
    Bioorg Med Chem 15:4406-18. 2007
    ..The dyes were found to show mixed binding modes...