Stephen W Duffy
Affiliation: American Cancer Society
- The impact of organized mammography service screening on breast carcinoma mortality in seven Swedish countiesStephen W Duffy
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, PO Box 123, Lincoln s Inn Fields, London WC2A 3PX, United Kingdom
Cancer 95:458-69. 2002..e., nonattenders) after the initiation of organized screening...
- Overdiagnosis, sojourn time, and sensitivity in the Copenhagen mammography screening programAnne Helene Olsen
Cancer Research UK, Department of Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, Charterhouse Square, London, United Kingdom
Breast J 12:338-42. 2006..A modest overdiagnosis was estimated for the Copenhagen screening program, deriving almost exclusively from the first screen. The CIs were very broad, however, and estimates from larger datasets are warranted...
- Bayesian evaluation of breast cancer screening using data from two studiesJonathan P Myles
Department of Mathematics, Statistics and Epidemiology, Cancer Research UK, London, UK
Stat Med 22:1661-74. 2003..The method is applied to the synthesis of two studies of mammographic screening in women with a family history of breast cancer, one in Manchester and one in Kopparberg, Sweden...
- Breast cancer in limited-resource countries: early detection and access to careRobert A Smith
American Cancer Society, Atlanta, Georgia 30329, USA
Breast J 12:S16-26. 2006..Ideally, for complete evaluation, such projects require notification of deaths among breast cancer cases and staging of diagnosed tumors...
- The randomized trials of breast cancer screening: what have we learned?Robert A Smith
American Cancer Society, 1599 Clifton Road, NE, Atlanta, GA 30329, USA
Radiol Clin North Am 42:793-806, v. 2004..The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality...
- Prospective estimation of rates of change in mammographic parenchymal patterns: influence of age and of hormone replacement therapyJonathan P Myles
Cancer Research UK, Department of Mathematics, Statistics and Epidemiology, Wolfson Institute of Preventitive Medicine, Charterhouse Square, London EC1M 6BQ, UK
Breast 13:56-60. 2004..The probability of non-dense patterns and the rate of change to non-dense patterns are reduced with HRT use. Errors of classification are relatively rare, but are dependent on the age of the subject...
- Time-dependent effects on survival in breast carcinoma: results of 20 years of follow-up from the Swedish Two-County StudyJane Warwick
Department of Epidemiology, Mathematics, and Statistics, Cancer Research UK, Wolfson Institute of Preventive Medicine, London, UK
Cancer 100:1331-6. 2004..However, to the authors' knowledge, the effect of these factors in the longer term (>10 years after diagnosis) is not yet clear...
- Overdiagnosis and overtreatment of breast cancer: estimates of overdiagnosis from two trials of mammographic screening for breast cancerStephen W Duffy
Cancer Research UK Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
Breast Cancer Res 7:258-65. 2005..Our results suggest that overdiagnosis in mammography screening is a minor phenomenon, but further studies with very large numbers are required for more precise estimation...
- Tumor size and breast cancer detection: what might be the effect of a less sensitive screening tool than mammography?Stephen W Duffy
Cancer Research UK Center for Epidemiology, Mathematics, and Statistics, Wolfson Institute of Preventive Medicine, London, United Kingdom
Breast J 12:S91-5. 2006..Our findings suggest that a less sensitive tool might be expected to confer a breast cancer mortality reduction about half of that observed with mammography...
- Re: Efficacy of breast cancer screening in the community according to risk levelStephen W Duffy
J Natl Cancer Inst 97:1703; author reply 1703-4. 2005
- Some current issues in breast cancer screeningStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London EC1M 6BQ, UK
J Med Screen 12:128-33. 2005..This paper describes examples of approaches to the above issues, along with some important results...
- The mammographic screening trials: commentary on the recent work by Olsen and GøtzscheStephen W Duffy
CA Cancer J Clin 52:68-71. 2002
- The controversy over breast cancer screeningStephen W Duffy
Hosp Med 63:708-9. 2002
- Screening for breast cancerStephen W Duffy
Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary University of London, London EC1M 6BQ, UK
Surg Oncol Clin N Am 14:671-97. 2005....
- Some issues in screening for breast and other cancersStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London
J Med Screen 13:S28-34. 2006..There are some issues in screening for cancer, especially breast cancer, which are worthy of further study...
- Mammography service screening and mortality in breast cancer patients: 20-year follow-up before and after introduction of screeningLaszlo Tabar
Department of Mammography, Central Hospital, Falun, Sweden
Lancet 361:1405-10. 2003..We aimed to assess the long-term effect of mammographic screening on death from breast cancer, taking into account potential biases from self-selection, changes in breast cancer incidence, and classification of cause of death...
- Mammographic screening: a key factor in the control of breast cancerLaszlo Tabar
Department of Mammography, Central Hospital, Fallun, Sweden
Cancer J 9:15-27. 2003
- Update on effects of screening mammographyLaszlo Tabar
Lancet 360:337; author reply 339-40. 2002
- Are breast cancer screening programmes increasing rates of mastectomy? Observational studyEugenio Paci
Unit of Epidemiology, Centre for the Study and Prevention of Cancer CSPO, Via di S Salvi 12, 50135 Florence, Italy
BMJ 325:418. 2002
- Correcting for lead time and length bias in estimating the effect of screen detection on cancer survivalStephen W Duffy
Cancer Research UK Centre for Epidemiology, Mathematics and Statistics, Wolfson Institute for Preventive Medicine, London, United Kingdom
Am J Epidemiol 168:98-104. 2008..Here they demonstrate these methods using a series of 25,962 breast cancer cases (1988-2004) from the West Midlands, United Kingdom...
- Lymph node status and breast cancer-related lymphedemaAnand D Purushotham
King s College London, London, United Kingdom
Ann Surg 246:42-5. 2007..This study examines the association between nodal positivity and risk of developing breast cancer-related lymphedema (BCRL) in patients who underwent axillary lymph node dissection (ALND)...
- Single reading with computer-aided detection and double reading of screening mammograms in the United Kingdom National Breast Screening ProgramFiona J Gilbert
Department of Radiology, University of Aberdeen, Lilian Sutton Bldg, Foresterhill, Aberdeen, Scotland
Radiology 241:47-53. 2006..To retrospectively determine if the use of a computer-aided detection (CAD) system can improve the performance of single reading of screening mammograms to match that of double reading in the United Kingdom...
- Cancer screening in AsiaStephen W Duffy
J Med Screen 13:S1. 2006
- Commentary: axillary dissection in breast cancer updatedStephen W Duffy
Breast 14:83-4. 2005
- Mammographic parenchymal patterns and self-reported soy intake in Singapore Chinese womenRupert W Jakes
National Medical Research Council Clinical Trials and Epidemiology Research Unit, Singapore 169039
Cancer Epidemiol Biomarkers Prev 11:608-13. 2002..20-0.98). The association between high soy intake and a reduced risk of mammographic parenchymal patterns that are associated with high breast cancer risk may have important implications in breast cancer prevention...
- Prognosis of small hepatocellular carcinoma treated by percutaneous ethanol injection and transcatheter arterial chemoembolizationChao Sheng Liao
Department of Internal Medicine, Shin Kong Wu Ho Su Memorial Hospital, No 95, Wen Chang Road, Taipei, Taiwan, Republic of China
J Clin Epidemiol 55:1095-104. 2002..Our results suggest the optimal frequency of clinical surveillance of small HCC cases after treatment should take account of increased hazard rate with time and the roles of pretreatment clinico-pathologic variables...
- The Gothenburg Breast Screening TrialNils Bjurstam
Department of Radiology, Center for Breast Imaging, University Hospital of North Norway, Tromsø, Norway
Cancer 97:2387-96. 2003..Although there is evidence for a reduction in breast carcinoma mortality with mammographic screening, some doubts have been expressed, and there is still uncertainty regarding the age specific effects...
- Misclassification in a matched case-control study with variable matching ratio: application to a study of c-erbB-2 overexpression and breast cancerStephen W Duffy
Department of Epidemiology, Wolfson Institute of Preventive Medicine, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK
Stat Med 22:2459-68. 2003..An example is given from a study of risk factors for progression of benign breast disease to breast cancer, in which the risk factor is a biological marker measured with poor sensitivity...
- Imputation of a true endpoint from a surrogate: application to a cluster randomized controlled trial with partial information on the true endpointRichard M Nixon
MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge, CB2 2SR, UK
BMC Med Res Methodol 3:17. 2003..Data are only available for the true end point on a sub set of the practices, but there are surrogate data for almost all of the audited practices and for most of the remaining practices...
- A breast cancer prediction model incorporating familial and personal risk factorsJonathan Tyrer
Department of Epidemiology, Mathematics and Statistics, Cancer Research UK
Stat Med 23:1111-30. 2004..This risk was further refined based on the woman's personal history. The model has been incorporated into a computer program that gives a personalised risk estimate...
- Tamoxifen and breast density in women at increased risk of breast cancerJack Cuzick
Cancer Research UK, Department of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, Queen Mary College, University of London, London, UK
J Natl Cancer Inst 96:621-8. 2004..We investigated mammographic breast density in healthy women with an increased risk of breast cancer at baseline and during 54 months of tamoxifen treatment...
- Progression rates of colorectal cancer by Dukes' stage in a high-risk group: analysis of selective colorectal cancer screeningJau Min Wong
Department of Internal Medicine, College of Public Health, National Taiwan University Hospital, No 19 Hsuchow Road, Taipei 100, Taiwan
Cancer J 10:160-9. 2004..The progression rates of colorectal cancer by Dukes' stage in a high-risk group were estimated and applied to evaluate the efficacy of different screening regimens...
- Mammographic tumor features can predict long-term outcomes reliably in women with 1-14-mm invasive breast carcinomaLaszlo Tabar
Mammography Department, Central Hospital, Falun, Sweden
Cancer 101:1745-59. 2004..The radiologic images of 1-14-mm invasive breast carcinomas can be classified into 5 separate categories. The use of these mammographic indicators to predict patient outcome has important prognostic and therapeutic implications...
- Single reading with computer-aided detection for screening mammographyFiona J Gilbert
Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, Scotland, United Kingdom
N Engl J Med 359:1675-84. 2008..We conducted a trial to determine whether the performance of a single reader using a computer-aided detection system would match the performance achieved by two readers...