Ved P Sharma

Summary

Affiliation: Albert Einstein College of Medicine
Country: USA

Publications

  1. pmc Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells
    Ved P Sharma
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA Electronic address
    Curr Biol 23:2079-89. 2013
  2. pmc Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis
    Brian T Beaty
    Department of Anatomy and Structural Biology and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461
    J Cell Biol 205:737-51. 2014
  3. pmc Spatial regulation of RhoC activity defines protrusion formation in migrating cells
    Jose Javier Bravo-Cordero
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA
    J Cell Sci 126:3356-69. 2013
  4. pmc High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis
    Ved P Sharma
    Department of Anatomy and Structural Biology and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, USA
    Methods Mol Biol 1046:343-57. 2013
  5. pmc An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction
    Ved P Sharma
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA
    Methods Mol Biol 1172:115-23. 2014
  6. pmc MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma
    Lizandra Jimenez
    From the Departments of Pathology Ms Jimenez and Drs Harris, OW, Prystowsky, Childs, and Segall and Anatomy and Structural Biology Ms Jimenez and Drs Sharma, Condeelis, and Segall, Albert Einstein College of Medicine, Bronx, New York
    Arch Pathol Lab Med 139:1349-61. 2015
  7. pmc β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation
    Brian T Beaty
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, New York, NY 10461, USA
    Mol Biol Cell 24:1661-75, S1-11. 2013

Collaborators

Detail Information

Publications7

  1. pmc Tks5 and SHIP2 regulate invadopodium maturation, but not initiation, in breast carcinoma cells
    Ved P Sharma
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA Electronic address
    Curr Biol 23:2079-89. 2013
    ..Tks5 regulates invadopodium formation, but the precise timing during invadopodium lifetime (initiation, stabilization, maturation) when Tks5 plays a role is not known...
  2. pmc Talin regulates moesin-NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis
    Brian T Beaty
    Department of Anatomy and Structural Biology and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461
    J Cell Biol 205:737-51. 2014
    ..Thus, our findings provide a novel understanding of how intracellular pH is regulated and a molecular mechanism by which talin enhances tumor cell invasion and metastasis...
  3. pmc Spatial regulation of RhoC activity defines protrusion formation in migrating cells
    Jose Javier Bravo-Cordero
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA
    J Cell Sci 126:3356-69. 2013
    ..These findings provide a new insight into the dynamic plasticity in the amplitude and distribution of barbed ends, which can be modulated by fine-tuning RhoC activity by upstream GEFs and GAPs for directed cell motility. ..
  4. pmc High-resolution live-cell imaging and time-lapse microscopy of invadopodium dynamics and tracking analysis
    Ved P Sharma
    Department of Anatomy and Structural Biology and Gruss Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, NY, USA
    Methods Mol Biol 1046:343-57. 2013
    ..We also describe an ImageJ plugin that we have developed for tracking of invadopodia and lifetime analysis. ..
  5. pmc An in vitro one-dimensional assay to study growth factor-regulated tumor cell-macrophage interaction
    Ved P Sharma
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA
    Methods Mol Biol 1172:115-23. 2014
    ....
  6. pmc MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial Activity in Head and Neck Squamous Cell Carcinoma
    Lizandra Jimenez
    From the Departments of Pathology Ms Jimenez and Drs Harris, OW, Prystowsky, Childs, and Segall and Anatomy and Structural Biology Ms Jimenez and Drs Sharma, Condeelis, and Segall, Albert Einstein College of Medicine, Bronx, New York
    Arch Pathol Lab Med 139:1349-61. 2015
    ..Increasing miR-375 expression in HNSCC cell lines to levels found in normal cells results in suppressed invasive properties. HNSCC invasion is mediated in part by invadopodia-associated degradation of the extracellular matrix...
  7. pmc β1 integrin regulates Arg to promote invadopodial maturation and matrix degradation
    Brian T Beaty
    Department of Anatomy and Structural Biology, Albert Einstein College of Medicine of Yeshiva University, New York, NY 10461, USA
    Mol Biol Cell 24:1661-75, S1-11. 2013
    ..These results describe a fundamental role for β1 integrin in controlling actin polymerization-dependent invadopodial maturation and matrix degradation in metastatic tumor cells...